EP2799141A2 - Dispositif pour la manipulation de liquides à attacher à une bouteille - Google Patents

Dispositif pour la manipulation de liquides à attacher à une bouteille Download PDF

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Publication number
EP2799141A2
EP2799141A2 EP14002517.2A EP14002517A EP2799141A2 EP 2799141 A2 EP2799141 A2 EP 2799141A2 EP 14002517 A EP14002517 A EP 14002517A EP 2799141 A2 EP2799141 A2 EP 2799141A2
Authority
EP
European Patent Office
Prior art keywords
piston rod
sensor
piston
bottle
measuring strip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP14002517.2A
Other languages
German (de)
English (en)
Other versions
EP2799141A3 (fr
EP2799141B1 (fr
Inventor
Dieter Böhm
Wolfgang Ettig
Peter Mahler
Jürgen Schraut
Roland Wohner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brand GmbH and Co KG
Original Assignee
Brand GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brand GmbH and Co KG filed Critical Brand GmbH and Co KG
Priority to EP19158248.5A priority Critical patent/EP3508274B1/fr
Publication of EP2799141A2 publication Critical patent/EP2799141A2/fr
Publication of EP2799141A3 publication Critical patent/EP2799141A3/fr
Application granted granted Critical
Publication of EP2799141B1 publication Critical patent/EP2799141B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0203—Burettes, i.e. for withdrawing and redistributing liquids through different conduits
    • B01L3/0206—Burettes, i.e. for withdrawing and redistributing liquids through different conduits of the plunger pump type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/08—Ergonomic or safety aspects of handling devices
    • B01L2200/087—Ergonomic aspects
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B01L2200/146—Employing pressure sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/024—Storing results with means integrated into the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B01L2300/027—Digital display, e.g. LCD, LED
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/048—Function or devices integrated in the closure enabling gas exchange, e.g. vents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated

Definitions

  • the invention relates to a bottle attachment for handling liquids. These devices involve the accurate metering and delivery of fluids from a storage bottle or other storage container, with accurate metering in picking up a partial fluid volume from the storage bottle or the like into the device and / or dispensing a partial fluid volume out of the device to the outside into a container.
  • Bottle attachments of the type in question are in particular burettes and dispensers.
  • Such bottle top devices are widely used in chemistry, biology and pharmacy in the laboratory and in production.
  • liquid in the present context refers to liquids which are used extensively in chemistry, biology, pharmacy, etc. in the laboratory and in production, in particular liquids having a relative viscosity of up to about 300 (viscosity based on the viscosity of water under normal conditions ). It is therefore the fluid range from very fluid to slightly viscous.
  • a manually operated burette is used in titration to determine the unknown amount of a solute from the consumption of a reagent liquid of known concentration.
  • a burette is required to quickly and accurately dispense and display the particular amount of fluid.
  • High demands are placed on the precision of the liquid delivery as well as on the operator safety (General Catalog 600 "Laboratory Equipment from Brand” of BRAND GMBH + CO KG 09/01, No. 9963 00, " Burette Digital III ", pages 27 to 34 ).
  • the bottle top device is described in its operating position, that is mounted in its position on a storage bottle and aligned substantially vertically.
  • valve block there is regularly a suction valve, the sosstechnikskelt allowed to suck from the storage bottle by means of an intake manifold Approximately horizontally from the valve block from an exhaust line extends with a discharge valve therein. Since the discharge line protrudes approximately horizontally from the valve block and often still carries an additional switching valve, this is the side from which an operator works with the bottle top unit. This page will be referred to below as “front” or “front”. The opposite side is the “back” or “back”. In the case of a bottle-top device, a display with corresponding operating elements is regularly at the front.
  • a well-known bottle attachment for handling liquids (see the General Catalog 600 "burette Digital III", as stated above) is characterized in that the cylinder-piston assembly is covered by a closed top outer housing from above. This outer housing moves together with the piston rod relative to the cylinder upwards. To accomplish this, located on the cylinder a vertically extending rack, with a pinion on a drive shaft which is mounted in the outer housing, meshes.
  • the piston drive this bottle attachment device is designed for manual operation and therefore carries the drive shaft there at both ends outside the outer housing each have a manual control knob.
  • a bottle attachment in the form of a piston burette with digital display, in which a the piston drive, the display, a sensor assembly and an electronic control receiving housing is in a fixed, non-variable relative position to the valve block ( DE-C-35 01 909 ).
  • the outer housing is not closed, but the piston rod passes through the housing from bottom to top already in the lowest position of the piston in the cylinder.
  • the piston rod moves up out of the housing.
  • the teaching of the present invention is based on the problem to increase the accuracy of such a bottle attachment device.
  • the surface of the optically active measuring strip facing the sensor forms a plane which lies next to or on the longitudinal center axis of the piston rod as soon as possible.
  • the sensor detecting the magnetic field of the measuring strip is located next to or on the longitudinal central axis of the piston rod, ie is positioned.
  • the longitudinal center axis of the piston rod should lie between the sensor-facing surface of the measuring strip and the sensor itself when the piston rod is in the set position.
  • the teaching of the present invention is based on a further problem to provide a bottle top apparatus for handling liquids, which achieves a particularly high level of user-friendliness and operator safety.
  • the present invention solves the above-indicated problem with a bottle-top device having the features of claim 12.
  • the solution of claim 12 has a displacement of at least one actuating button of the display on the front of the outer housing on the top of the object. It can be arranged on the top of the outer housing depending on the space and requirements but also two or even more buttons.
  • the outer housing is closed on the top side and comprises the cylinder-piston arrangement from above.
  • the solution makes use of this fact known for decades to advantage for an optimized operation possibility of the bottle top attachment.
  • An operating button which is often used when working with the bottle top unit, can be actuated here by pressure from above. As a result, a quick and error-free operation is possible without a serious tilting moment is exerted on the bottle top unit and the storage bottle underneath. Unlike the arranged on the front of the outer case operating buttons thus no holding back the outer housing is required.
  • the actuating button arranged on the upper side of the outer housing may be a single, large-area button bordering the outer housing at the edge.
  • a circuit board is arranged, which carries a push button, which is actuated by the actuating button.
  • the board is then seated in a slot of the receiving compartment.
  • the board may be connected to the circuit board via a film hinge, which is preferably formed by a circuit film web.
  • the outer housing is provided with ventilation openings, which are arranged to achieve convection both centrally and / or down and up on the outer housing.
  • the piston drive is designed for manual operation and has a drive shaft which carries at one end or at each end outside of the outer housing a manual operation knob and that central ventilation openings are concealed under the hand operation knob or the hand operation knobs are arranged.
  • lower ventilation openings are arranged at the edge close to the valve block under at least one protective cap.
  • the solutions according to the invention which in particular increase operator safety, can be used in principle in the case of both previously treated types of bottle attachment devices, that is to say with a traveling outer housing and with an outer housing fixedly arranged on the valve block.
  • the term "fixed” in this context means that the outer housing is not moved relative to the valve block in this variant, when the piston of the cylinder-piston assembly is moved.
  • this outer housing may well be detachable from the valve block to perform repairs or cleaning or sterilization of the cylinder and / or the piston or other assemblies.
  • a displacement measuring strip is located directly on the piston rod, which extends axially in the direction of the piston rod ( DE-C-35 01 909 ).
  • the measuring strip is an optical scale and the sensor arrangement is an incident light system.
  • the measuring strip is part of a capacitive system, too which also includes the sensor. Opposing electrodes are arranged so that two pairs of measuring capacitances for measuring the relative movement between the measuring strip and the sensor are formed.
  • the piston rod carries a magnetic strip. Adjacent to the piston rod, a reading head is fixedly provided in the housing, which is aligned with the magnetic measuring strip and separated therefrom by a gap. An electronic control circuit is coupled to the read head, which reads the measurement information on the magnetic strip and injects appropriate pulses into the control circuit. This converts the pulses and controls a digital display, which in turn indicates the volume of liquid dispensed based on the relative movement between the piston and cylinder.
  • the section number of the displacement gauge is limited for mechanical reasons (typically a section is about 1 mm long), a much higher resolution of the measurements can only be achieved by directly evaluating the analog sinusoidal (and cosine) signals rather than merely to use their zero crossings.
  • One has a sinusoidal signal and a cosinusoidal signal, because one usually operates with two magnetic field sensitive encoders which are offset in pitch of the displacement gauge so as to emit two signals offset by a quarter of a period.
  • the previously indicated problem of optimizing the measuring system in devices of the type in question is achieved in that the sensor arrangement is arranged in a fully closed to the measuring strip receiving pocket.
  • the sensor arrangement can optionally be cast in the receiving pocket with potting compound in the rear, in order to ensure an optimum protective effect for the sensor arrangement.
  • a magnetic field-sensitive sensor arrangement is concerned with a correspondingly magnetized measuring strip.
  • An optical sensor arrangement uses an optical scale.
  • a suitable alternative has a wall portion of the receiving pocket, which is designed as a film.
  • This film should be extremely thin and have a low permeability to the gases occurring.
  • Such a thin film can even consist of transparent material, so that the sensor of the sensor arrangement can work optically.
  • the receiving pocket is provided with slot connections that allow an exact alignment of the receiving pocket on the measuring strip when installed in the device.
  • the senor is arranged in the receiving pocket at its side facing the measuring strip behind a thin-walled wall portion of the receiving pocket.
  • the sensor has been brought as close as possible to the gauge, without actually touching it, and while maintaining a gas-tight seal of the sensor assembly to the interior of the device.
  • the receiving pocket consists of a chemical-resistant plastic, in particular of PEEK.
  • the sensor of the sensor arrangement is expediently seated on a board inserted in the receiving pocket in an insertion guide, specifically on its front edge (see here the above explanations of the receiving pocket).
  • the above-mentioned problem is solved in that the sensor is designed as a magnetoresistive sensor system, in particular based on the AMR effect, and that the evaluation circuit has a largely highly integrated, cost-effective mixed-signal controller, the converted analog sensor signals directly via an interpolation software evaluates.
  • Mixed-signal controllers are microcontrollers that connect various electronic processing functions, which are also suitable for evaluating the sensor signals via interpolation software, with the functions of an A / D converter.
  • a mixed-signal microcontroller replaces a three-stage arrangement of A / D converter, processing stage with processing software and output stage.
  • Such a mixed-signal microcontroller is regularly far cheaper to use at the signal level of AMR sensors than a three-stage arrangement.
  • Microcontrollers are offered by different providers with different power spectra (see for example the Datasheet "MSP 430 x 33 x MIXED SIGNAL MICROCONTROLLERS", February 1998, Texas Instruments ). With a mixed-signal microcontoller you not only create a simple signal processing solution, but in particular a very low power consumption both during operation and when idle. (For detailed information, please refer to the relevant data sheets, in particular the previously mentioned data sheet.)
  • Mixed signal controllers can be realized in different versions, for example as PSoC (Programmable System on a Chip), as DSP (Digital Signal Processor) or as FPGA (Field Programmable Gate Array).
  • PSoC Programmable System on a Chip
  • DSP Digital Signal Processor
  • FPGA Field Programmable Gate Array
  • the latter has a purely digital input transducer, allowing a discrete upstream A / D converter to turn the overall arrangement into a mixed-signal controller of the type described.
  • the evaluation by means of the evaluation circuit with an ON / OFF duty cycle of about 0.1 to about 0.02, preferably between about 0.05 and about 0.03, in particular with an ON Time from about 0.6 ms to about 0.1 ms, in particular between about 0.3 ms and about 0.15 ms.
  • the interpolation software operates at an interpolation rate between 200 and 1,000, in particular between about 400 and about 600, preferably about 500
  • the device according to the invention a structure can be realized, which ensures safe operation and at the same time easy handling.
  • the power consumption of the measuring system is low and the cost of production are also lower than with traditional bottle-top devices.
  • the present bottle attachment device is particularly preferably a burette, so executed as a burette.
  • Fig. 1 shows a preferred embodiment of a bottle attachment according to the invention for handling liquids, here in the form of a burette.
  • Bottle-top dispensers emerge, for example, from the DE-U-88 00 844 and in particular the EP-A-0 542 241 , which will be discussed below.
  • FIG. 1 It has an outer housing 2 and is a total of a mounting assembly 3, here a cap, attached to a bottle neck of the storage bottle 1, screwed here.
  • a display 4 At the top of the outer housing 2, aligned in front, there is a display 4 with a display field 5, in particular for a digital display, preferably with LCD elements, as well as with actuating elements, in particular actuating buttons 6.
  • a discharge line 7 which is arranged in the illustrated embodiment in an angle-shaped holder 8 and closed at the end by means of a cap 9 for closing and as drip protection.
  • the illustrated bottle top unit has in the outer housing 2, first a valve block 10. At this is attached or integrally formed the already mentioned mounting assembly 3, with the fact of the valve block 10 is mounted on the storage bottle 1. At the same time then also the outer housing 2 is mounted on the storage bottle 1.
  • valve block 10 as a one-piece made of plastic, in particular made of chemical resistant plastic component, which is provided with a plurality of channels and internals.
  • the construction largely corresponds to the valve block ofaunaufsatzdispensers, from the EP-A-0 542 241 is known and belongs to the prior art.
  • the mounting assembly 3 is designed as compared to the valve block 10 freely rotatable cap.
  • a suction valve insert 11 to which an intake line 12, which is shown shortened here for simplicity, is connected to the bottom of the storage bottle 1 into it.
  • At the top closes to the intake valve insert 11 in the valve block 10 to an intake passage 13, from which at about half the height in Fig. 2 branched off to the right discharge channel 14.
  • a discharge valve insert 15 In a recess of the valve block 10 on the discharge channel 14 is a discharge valve insert 15. This is part of a valve block 10 attached to the valve body here 16 of a changeover valve 17. Downstream, the discharge line 7 connects to the changeover valve 17 in the holder 8.
  • the holder 8 is arcuate and leads the discharge line 7 in the same arc, so that the discharge opening facing downward. There it is closed with the cap 9.
  • the switching valve 17 has a valve body 16 rotatable about a vertical axis of rotation valve body 18, which also has a in Fig. 1 recognizable knob 19 can be adjusted by hand. Below the discharge valve insert 15 extends in the valve body 16, a return passage 20, which continues in the valve block 10 to a downwardly outgoing return line 21.
  • the switching valve 17 is switched to passage, so that the discharge channel 14 is connected to the discharge line 7.
  • the discharge channel 14 is connected to the return passage 20, so that liquid is conveyed in the circuit from the storage bottle 1 and the return line 21 back into the storage bottle 1. More specifically, for the entire background of this so - called “back - dosing”, please refer to the detailed explanations given in the EP-A-0 542 241 to get expelled.
  • the valve block 10 further includes near the back of a bottle venting line 22, which opens in a rearwardly, radially open plug receptacle 23.
  • a plug 24 closing this or a similar closure element, but having a small passage opening, so that the interior of the storage bottle 1 is connected via the bottle venting line 22 and this passage in the plug 24 with the ambient atmosphere.
  • a pressure equalization in the storage bottle 1 is possible.
  • existing valve block 10 is a preferably and also made of glass existing cylinder 26 fixed and sealed against the valve block 10 in a cylinder mount 25. Specifically, the cylinder 26 is compressed in the cylinder receptacle 25.
  • the illustrated bottle top unit While in the area of the valve block 10, the illustrated bottle top unit is designed according to the already extensively known and very well-proven prior art, the construction in the field of cylinder-piston arrangement is significantly different than before.
  • Fig. 2 combined with Fig. 3 and Fig. 4 makes it clear that initially a cylinder 26 surrounding, upwardly beyond the cylinder 26 also extending, supporting frame 30 is provided.
  • This frame 30 is connected at the lower end with the valve block 10 fixed in an axially precisely determined position, but in principle detachable from the valve block 10.
  • the solubility of the frame 30 from the valve block 10 is here realized by the fact that at the top of the valve block 10, an external thread is provided and that the frame 30 has a flange below, which is provided with a cap 31 with internal thread.
  • the larger illustration in the Fig. 3 and 4 makes it clear that the cap 31 is guided on the frame 30 and can escape upwards.
  • the frame 30 can thus be brought first with its lower edge in the desired position on the valve block 10. Then, while maintaining this position, the cap 31 can be screwed onto the external thread on the valve block 10 and the frame 30 can be fixed relative to the valve block 10.
  • the frame 30 It is also essential for the frame 30 that it also receives or carries the piston drive 29.
  • the piston drive 29 does not have to be part of the frame 30, in any case the frame 30 represents the supporting component for the piston drive 29 and determines its position relative to the valve block 10.
  • the frame 30 is expanded and extended block-like upwards there and has there various recesses for receiving various parts of the piston drive 29. This will be discussed later.
  • a releasably connected to the valve block 10 outer housing 2 is provided. This encloses the frame 30 on the outside, thus forming the outer shell of the bottle top unit and protects the internal components. It extends beyond the piston drive 29 on the frame 30 in any case slightly upwards and is closed in the illustrated and preferred embodiment above.
  • the illustrated and preferred embodiment can in Fig. 2 in conjunction with the Fig. 3 and 4 Furthermore, recognize that the cap 31 can not be operated easily here. Rather, it is provided for safety reasons and for reasons of accessibility in the outer housing 2, that the cap 31 can be operated only with a special tool 32. This tool 32 can be seen in Fig. 2 top left in a suspension at the back of the outer housing 2.
  • the small stroke of the piston 27 in the bottle cap device according to the invention facilitates the closed design of the outer housing 2, because the complete stroke of the piston rod 28 unwound within the outer housing 2 can be.
  • the outer housing 2 still does not have to be made excessively high. Also, it does not have to ride along with the piston rod 28 in whole or in part.
  • the construction according to the invention thus increases the operating safety of the bottle top unit.
  • the lower the bottle top unit the higher the stability of a stock bottle 1 equipped with such a bottle top unit.
  • the stroke quotient has a value of just under 2.0 in the illustrated embodiment for the nominal volume of 25 ml and a value of approximately 50 ml for the nominal volume 1.4. With a nominal volume of 100 ml, which would represent a rather unusually large arrangement, one would come to a value of about 1.0, which would mean an effective diameter of the piston 27 of about 50 mm.
  • the execution of the cylinder 26 as a calibrated glass tube with extremely high precision further increases the accuracy of the bottle top unit in total.
  • the use of a calibrated glass tube as a cylinder 26 is useful and expedient here because of the measures taken otherwise.
  • Fig. 3 and 4 show, moreover, that in the upper part of the frame 30, a drive shaft 33 of the piston drive 29 is mounted.
  • the primary objective of the invention is a manually actuated bottle attachment device with an electronic, in particular digital measured value acquisition and display.
  • the piston drive 29 is designed for manual actuation and the drive shaft 33 carries a manual operation knob 38 at one end or at each end outside the outer housing 2. It can be seen the two hand control knobs 38 left and right on the outer housing 2 in Fig. 1 ,
  • the geared connection between the drive shaft 33 and the pinion 35 is designed so that a rotation of the manual operation knob 38 causes a downward movement of the piston 27 forward and downward.
  • Ergonomic studies have shown that good dosing accuracy can be optimally associated with quickly picking up or dispensing large quantities of fluid when the maximum stroke of the piston 27 equals five to ten of the manual operation knob 38.
  • the design of the piston 27 in the cylinder 26 is important.
  • the piston 27 is made in one piece with the piston rod 28, or designed as a separate part and firmly attached to the piston rod 28, in particular screwed
  • the illustrated embodiment shows the piston rod 28, and screwed thereto by means of a central fastening screw 39, the piston 27, which here carries him a bottom side and circumferentially comprehensive slide piece 40 made of a very good sliding material, in particular PTFE.
  • the sliding piece 40 forms a cylinder 26 under pressure applied to the sliding ring 40a, which is deposited to generate pressure with a piston 27 supported on the spring ring 42 from a preferably also resistant to chemicals material.
  • the spring ring 42 is shown in the drawing as a hollow chamber ring, for example made of chemical-resistant elastomer material. It is essential that the sliding ring 40 a itself does not have to apply the force to achieve the sealing effect of the sliding piece 40 on the inner surface of the cylinder 26. This is taken over by the spring ring 42, which is adapted for it. Incidentally, it can scarcely be recognized in the drawing that the outer circumferential surface of the sliding ring 40a can still be structured in order to realize, for example, a multi-start scraper ring.
  • the piston 27 is not driven down against the valve block 10, but the piston rod 28 or the piston 27 up against a stop 43.
  • the stop 43 can be adjustable and should be removable in any case in order to be able to pull out the piston 27 together with the piston rod 28, for example for cleaning or sterilization measures. This measure makes it possible, even in the lowest position of the piston 27, to leave a small gap to the valve block 10 or to the bottom of the cylinder 26. Bumps here can not bother you then.
  • the stop 43 engages near the piston drive 29 on the piston 27 fixedly connected to the piston rod 28. As a result, the stop 43 and the point of force application of the piston drive 29 on the piston rod 28 are close to each other.
  • the frame 30 is not designed as an open frame, but as a substantially closed housing, which is the case in the present embodiment (see in particular Fig. 2 and Fig. 4 ), it is recommended that the frame 30 in any case with a front view section 44 or a corresponding window and, as provided here ( Fig. 5 ), to provide a rear sight 45 or a corresponding window. This allows you to look into the cylinder 26 from the front or the back.
  • a viewing cutout or a window in the frame would not be of any use if the outer casing 2 were not covered by the viewing cutout 44; 45 or window of the frame 30 would have a corresponding window 46 and 47, respectively.
  • a viewing window may optionally be UV-protective colored, for example in brown color.
  • the front window 46 in the outer housing 2 is also in Fig. 1 to recognize.
  • Ventilation openings 48 which expediently to achieve convection in the middle, z. B. concealed under the manual operation knob 38, or below near the valve block 10 and above the upper end of the outer housing 2 are arranged.
  • the illustrated and preferred embodiment shows that the overhead ventilation openings 48 are arranged on the head of the outer housing 2, preferably under an actuating button 49 arranged on the upper side.
  • a large-area actuator button 49 which is labeled here with the word "Clear”, that is, represents a zeroing button. Such is often used when working with a burette.
  • the actuating button 49 on the top of the outer housing 2 is designed as a push button. Their operation is thus carried out by pressure from the top of the outer housing 2. Thus, a quick and error-free operation is possible without affecting the bottle top unit and the storage bottle underneath 1 a serious tilting moment is exercised.
  • buttons 6 Unlike the arranged on the front of the outer housing 2 operation buttons 6 thus no holding back the outer housing 2 is required.
  • the large-area actuating button 49 offers the possibility of hiding the ventilation opening 48 thereunder. This shows Fig. 2 ,
  • the outer housing 2 has a front housing shell 51 and a rear housing shell 52 detachably connected thereto.
  • the front housing shell 51 is hooked behind the valve block 10 and firmly anchored in the middle (or top) of the frame 30. It is screwed there.
  • the rear housing shell 52 is suspended at the top of the front housing shell 51. Below it is on the valve block 10 by means of the plug 24, which sits in the plug receptacle 23 and belongs to the bottle venting line 22, fixed. Other fixation options are given, for example, here by a screw. Appropriately here is the simultaneous use of the plug 24, also because this is particularly well accessible from the back of the bottle top device. In Fig. 5 the rear housing shell 52 has been removed and accordingly also the plug 24 is missing.
  • FIG. 2 and Fig. 5 First, located in the outer housing 2, here in the front housing shell 51, more precisely attached to this, from the rear (as here), accessible from the front and / or from above, to the interior of the This receptacle 53 is used to hold electronic devices, in particular a populated circuit board 54. In the receptacle 53 is also the electronics of the display 4 including the display panel fifth
  • the receiving compartment 53 is under the actuating button 49 angularly into the rear housing shell 52 continues.
  • this is another board 55, which carries a pushbutton 56, which is actuated by the actuating button 49.
  • This further board 55 is connected in the illustrated and preferred embodiment of the circuit board 54 via a film hinge 57 and sits even in a slot 58 of the receiving tray 53.
  • the film hinge 57 is formed in the illustrated and preferred embodiment of a circuit film web.
  • the receptacle 53 could be completed to the front by a possibly also the display 4 and the operation buttons 6 carrying compartment cover 59. Then, the receptacle 53 could be equipped with removed compartment cover 59 from the outside.
  • the port 60 represents an external interface of the electronic devices that can be used in any conventional manner.
  • the ventilation opening 48 below the actuating button 49 of the ventilation of the receiving compartment 53 are in Fig. 5 indicated, laterally below the actuating button 49 lying ventilation openings for the ventilation of the interior of the outer housing 2 in the rest responsible.
  • the receiving tray 53 is at least in the rearwardly extending portion narrower than the outer casing 2 and is arranged centrally.
  • Fig. 5 combined with Fig. 2 in that two battery compartments 61, namely right and left of the receiving compartment 53, are arranged in the outer housing 2, and here also in the front housing shell 51, that is, attached thereto.
  • Each battery compartment 61 is closed by a cover 62 to the interior of the outer housing 2 in the rest.
  • the lid 62 is in Fig. 2 recognizable, he has a handling tab 63.
  • Fig. 5 you can see the battery compartments 61 without the lid 62 and without batteries.
  • the battery compartments 61 are sealed by the lid 62 against the vapors occurring in the outer housing 2.
  • the two in Fig. 5 recognizable battery compartments 61 leave between them a free space in which the piston rod 28 can go up. Accordingly, the wall of the receiving compartment 53 has a corresponding course here, which gives the piston rod 28 the necessary clearance.
  • the openable design of the outer housing 2 with the substantially fixed front housing shell 51 and the easily removable rear housing shell 52 is a simple way for the user to disassemble the cylinder-piston assembly, the piston 27 together with the piston rod 28 on the one hand and the cylinder 26 on the other hand to clean and also to change the piston 27 or the slide 40 if necessary.
  • the piston rod 28, preferably on the opposite side of the tooth row 34 carries an axially extending on the piston rod 28 gauge 64 and that adjacent to the piston rod 28, preferably in the upper part of the frame 30, a Sensor arrangement 65 is arranged with a sensor 66 aligned on the measuring strip 64.
  • a direct measured value recording on the piston rod 28 is provided, as it is basically known from the above-described prior art. Play in translation devices, as occurs in electromechanical data acquisition is systematically excluded here. This is particularly useful here if the other measures for stiffening the mechanical arrangement and increasing the accuracy are also taken.
  • the illustrated embodiment shows that the measuring strip 64 is aligned here on one side form-fitting manner on the piston rod 28.
  • the measuring strip 64 with a one-sided axial stop 67 in a pocket placed on the piston rod 28 and potted with a preferably chemical resistant potting compound 68.
  • a potting compound 68 is easier to perform chemical resistant than normal glue. It also has a sufficient inherent elasticity to accommodate the minimum displacements of the measuring strip 64 relative to the piston rod 28.
  • measuring strips 64 made of plastic and offset with magnetic powder can be used.
  • Fig. 12 the assembly with piston 27, piston rod 28 and measuring strip 64 is shown. Contrary to the execution after Fig. 2 the measuring strip 64 as in the embodiment according to Fig. 11 a / 11 b arranged in the piston rod 28 near the central axis of the piston 27. The gauge 64 also does not become as in the embodiment Fig. 2 held. In this embodiment, the measuring strip 64 sits vertically near the piston 27 on the stop 67. The upper opposite end of the measuring strip 64 is displaced by a spring element 28 a vertically downward on the stop 67. Both contact surfaces are inclined, so that the measuring strip 64 is held in the direction of its lateral abutment against the piston rod 28.
  • Fig. 12 keeps flexible the measuring strip 64 on the piston rod 28 by the spring element 28a. Temperature changes and different elongations have no influence on the attachment. In addition, the assembly of the measuring strip 64 without aids and / or a curing time is positive with respect to costs for production and repair.
  • the spring element 28a and the piston rod 28 are made in one piece.
  • the spring element 28a could also be a separate component, which is fastened to the piston rod 28 and consists of another material with good elastic properties.
  • the spring element could 28a are designed so that it holds the measuring strip 64 in the direction of its lateral abutment against the piston rod 28 in a form-fitting manner, for example by means of a molded-on bracket.
  • the displacement measuring strip 64 (measuring strip 64) is magnetized in sections spaced apart or partially magnetized in opposite directions, with a pitch of between 0.3 mm and 2.0 mm, preferably and as a compromise between resolution and cost approximately 1 , 0 mm.
  • the illustrated and so far preferred embodiment shows a particularly advantageous embodiment of a non-optical, in particular a magnetic field-sensitive sensor assembly 65.
  • This is located in a measuring strip 64 and the interior of the outer housing 2 out completely closed receiving pocket 69.
  • This is in the illustrated embodiment in the Used frame 30, namely screwed to this with slot connections 70.
  • the slot connections 70 allow the exact alignment of the receiving pocket 69 on the measuring strip 64.
  • the senor 66 of the sensor assembly 65 is arranged in the receiving pocket 69 on its side facing the measuring strip 64 behind a thin-walled wall portion 71
  • the purpose of the arrangement is to bring the sensor 66 as close as possible to the measuring strip 64, without actually touching it, and while maintaining a gas-tight seal of the sensor assembly 65 to the interior of the outer housing 2 out.
  • FIG Fig. 6, 7 and 8th Details of the sensor arrangement 65 with the sensor 66 in the receiving pocket 69 are shown in FIG Fig. 6, 7 and 8th shown.
  • the sensor 66 of the sensor arrangement 65 is seated on a board 74 inserted in the receiving pocket 69 in a slide-in guide 73, namely at the front edge thereof Fig. 3 and Fig. 6 on the left immediately adjacent to the thin wall portion 71.
  • the wall section 71 here has, for example, only a thickness of about 0.1 to 0.2 mm. If the pitch of the measuring strip 64 is selected to be larger, the distance between the sensor 66 and the measuring strip 64 can also be greater. Then easier to produce, in particular injection-moldable wall sections can be designed, which will regularly have a slightly larger wall thickness of about 0.5 mm.
  • the receiving pocket 69 consists here of a total of a chemical-resistant and pourable temperature-stable plastic material, in particular PEEK. Length and width of the receiving pocket 69 are about 20 mm, the thickness of about 8 to 10 mm.
  • the wall portion 71 of the receiving pocket 69 can not be made in one piece with the receiving pocket 69, but separately. It would then be attached to the receiving pocket 69.
  • the receiving pocket 69 may have an opening in the region of the wall section 71.
  • a gas-tight film can be welded onto such an opening or otherwise fixed with the aid of and without auxiliaries, the opening on the receiving pocket 69.
  • Such a gas-tight film usually has a thickness of about 10 microns to about 500 microns.
  • This film now forms the wall section 71, which separates the sensor 66 from the measuring strip 64 in a gastight manner. In this way one can come to a very small distance of 0.1 mm or less.
  • the sensor arrangement 65 also has on the board 74 the evaluation circuit 72 for evaluating the output signals of the sensor 66 and for controlling the display 4.
  • the evaluation circuit 72 is constructed as a system solution with individual or multiple discrete components.
  • a space-saving, energy-saving and cost-effective evaluation circuit 72 is achieved with the use of a mixed-signal controller, which evaluates the converted analog sensor signals directly via an interpolation software.
  • the evaluation circuit 72 can also be realized with a software solution that is pure in the extreme case by means of a microprocessor or microcomputer, without departing from the spirit of the teaching of the present invention.
  • Fig. 7 shows a perspective view of the receiving pocket 69 with inserted board 74 obliquely from behind.
  • the board 74 is not yet shed.
  • the soldered to the board 74 and not molded with interface cable shown. It can be provided to completely shed the board 74 in the receiving pocket 69, and indeed with a chemical-resistant potting compound.
  • Fig. 8 shows an arrangement of a particularly useful sensor 66 for a sensor assembly 65 of a device according to the invention.
  • the sensor 66 is designed as a magnetoresistive sensor system based on the AMR effect.
  • this operating principle may be on the publication of Dr. Erik Lins, SENSITEC GmbH "Magnetoresistive with Optical Precision", dated August 1, 2005 , the disclosure of which is incorporated by reference into the disclosure content of the present application. This publication has been freely available on the Internet since August 2005.
  • Fig. 8 in short, shows two Wheatstone bridge circuits offset 45 ° from each other to produce a cosine signal (C) and a sine signal (S), taps at + C / -C and + S / -S.
  • the magnetization direction of the measuring strip 64 is defined by H, the angle between H and the direction of current flow is indicated by ⁇ .
  • ⁇ By forming quotients of sine and cosine (arctangent function), the angle information becomes independent of the amplitude of the signals.
  • the working distance between sensor 66 and measuring strip 64 is not particularly critical.
  • the separate evaluation of the sine and cosine signals provides some redundancy and, due to the fact that the sum of the squares is equal to 1, allows self-monitoring of the sensor 66 and offset amplitude correction, respectively.
  • a circuit arrangement 72 as described in US Pat Fig. 9 is shown as a block diagram.
  • the sensor 66 is supplied with a clocked supply voltage 80, which is adjustable via an amplitude setting 81 on the sensor 66.
  • the designated outputs (cos, sin) of the sensor 66 are connected to amplifiers 82, each with offset adjustment 82 '.
  • Assemblies 75, 85, 86, 87, 88, and 89 are implemented in the present preferred embodiment of a mixed signal controller. For more information on a mixed-signal controller, see the related notes and quotation point included in the general part of the description.
  • a magnetoresistive measuring system is in any case already quite expedient, at least considerably cheaper than an optoelectronic measuring system.
  • the evaluation takes place by means of the interpolation software with an ON / OFF duty cycle of about 0.1 to about 0.02, preferably between about 0.05 and about 0.03, in particular with an ON / OFF duty cycle. Time from about 0.6 ms to about 0.1 ms, in particular between about 0.3 ms and about 0.15 ms. It is particularly recommended that the interpolation software with an interpolation between 200 and 1,000, in particular between about 400 and about 600, preferably from about 500 works.
  • the adjustment speed of the piston 27 will not be greater than about 50 mm / s. Then the interpolation rate is tuned. This gives a resolution of the measuring path of about 2 ⁇ m and an accuracy of the measured value over the full measuring range of about 10 ⁇ m, the whole in a temperature range of + 10 ° C to about + 40 ° C.
  • Fig. 11a shows a precise alignment of the piston rod 28 on a side guide 90. It is provided here that on the same side on which the sensor assembly 65 is located, a side guide 90 is provided for the piston rod 28 and the sensor 26 is close to, preferably approximately at the level of Side guide 90 is arranged. This ensures that in the set position of the piston rod 28 in contact with the side guide 90 and the sensor 66 is aligned relative to the positioned on the piston rod 28 measuring strips 64 exactly. The parallelism of the measuring strip 64 with the sensor 66 is optimal over the full displacement of the piston rod 28.
  • Fig. 11b shows in conjunction with Fig. 11a in that a measurement error with regard to the distance measurement in the axial direction could also result from an inclination of the piston rod 28 in the cylinder 26, in particular relative to the piston 27.
  • This measurement error occurs in a device of the type in question because of the otherwise achieved high precision. It is caused by the fact that the piston rod 28 in the region of the piston drive 29 has a certain lateral play, for example of 0.3 mm. This leads to a minimal, but within the present Measuring accuracy disturbing inclination of the piston rod 28, which causes a Wegmesscons.
  • This arrangement rule for the measuring strip 64 on the piston rod 28 is based on the recognition that in a Auflichtsystem the surface of the measuring strip 64 is the interface between the measuring strip 64 and sensor 66. If I place these as close as possible to the longitudinal central axis of the piston rod 28, I minimize the measurement error resulting from the play-related inclination of the piston rod 28.
  • the sensor 66 which detects the magnetic field of the measuring strip 64 lies closest to or on the longitudinal central axis of the piston rod 28 as far as possible. This is in Fig. 11a, b shown.
  • the interface in the magnetoresistive measuring system is the sensor 66, which is penetrated by the field lines of the periodically magnetized measuring strip 64. Tilts the measuring strip 64 as in Fig. 11b Although the output field of the field lines moves slightly to the left, the tilting causes the direction of the field lines to also be tilted; these run slightly upward from the measuring strip 64 in the direction of the sensor 66.
  • the interface namely at the sensor 66, slightly changes only the amplitude, which is correctable, but not the phase position, which is crucial for the distance measurement.
  • the interface is somewhere between the two previously described orientations.
  • the sensor 66 in the sensor arrangement 65 no longer lies next to the piston rod 28 but in its light profile. Accordingly, it is recommended that the piston rod 28 has a corresponding position of the sensor 66 permitting recess or flattening.
  • Fig. 12 shows a particularly interesting constructive solution for fixing the measuring strip 64 in the piston rod 28, taking into account the above-mentioned boundary conditions. This has already been explained above.
  • the illustrated embodiments show that the sensor arrangement 65 is not arranged on the outer housing 2 but on the dimensionally stable frame 30.
  • the entire metrological chain is completely concentrated on the frame 30, so that its dimensional stability leads to the excellent accuracy of the bottle-top device according to the invention.
  • the measuring strip 64 is an optical scale and the sensor arrangement 65 is a high-resolution incident-light system, in particular with four incident-light diodes. Then, the construction in the area of the sensor arrangement 65 is of course different from what has been described above.
  • the accuracy of measurements in the bottle-top device according to the invention can be increased to an accuracy R of approximately +/- 0.06% and a coefficient of variation VK of approximately 0.02% at nominal volumes of 25 ml and 50 ml.
  • accuracy R of approximately +/- 0.06%
  • VK coefficient of variation
  • the high accuracy of the bottle top attachment according to the invention also stirs Therefore, that all the mechanically moving parts axially with respect to the valve block 10 are fixed precisely and dimensionally stable. This, in conjunction with the direct data acquisition directly on the piston rod 28 makes a backlash in reversing the direction of actuation superfluous.

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Measurement Of Length, Angles, Or The Like Using Electric Or Magnetic Means (AREA)
  • Loading And Unloading Of Fuel Tanks Or Ships (AREA)
EP14002517.2A 2006-12-07 2007-12-06 Dispositif pour la manipulation de liquides à attaché à une bouteille Active EP2799141B1 (fr)

Priority Applications (1)

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EP19158248.5A EP3508274B1 (fr) 2006-12-07 2007-12-06 Appareil posé sur bouteille destiné à la manipulation de liquides

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DE202006018527 2006-12-07
DE202006018526 2006-12-07
PCT/EP2007/010580 WO2008068013A2 (fr) 2006-12-07 2007-12-06 Appareil pièce rapportée pour bouteille pour la manipulation de liquides
EP07856393.9A EP2125223B1 (fr) 2006-12-07 2007-12-06 Appareil pièce rapportée pour bouteille pour la manipulation de liquides

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EP07856393.9A Division-Into EP2125223B1 (fr) 2006-12-07 2007-12-06 Appareil pièce rapportée pour bouteille pour la manipulation de liquides

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EP14002517.2A Active EP2799141B1 (fr) 2006-12-07 2007-12-06 Dispositif pour la manipulation de liquides à attaché à une bouteille
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DE202015000519U1 (de) 2015-01-23 2016-04-27 Brand Gmbh + Co Kg Ausstoßleitungsanordnung für ein Flaschenaufsatzgerät
DE202015000523U1 (de) 2015-01-23 2016-04-27 Brand Gmbh + Co Kg Ausstoßleitungsanordnung für ein Flaschenaufsatzgerät
DE202015000520U1 (de) 2015-01-23 2016-04-28 Brand Gmbh + Co Kg Ventilblockanordnung für ein Flaschenaufsatzgerät
DE202015000521U1 (de) 2015-01-23 2016-04-28 Brand Gmbh + Co Kg Ausstoßventilanordnung für ein Flaschenaufsatzgerät
DE102015000905A1 (de) 2015-01-23 2016-07-28 Brand Gmbh + Co Kg Zylinder-Kolben-Anordnung für ein Flaschenaufsatzgerät
DE102015000903A1 (de) 2015-01-23 2016-07-28 Brand Gmbh + Co Kg Ausstoßleitungsanordnung für ein Flaschenaufsatzgerät
DE102015000906A1 (de) 2015-01-23 2016-07-28 Brand Gmbh + Co Kg Ausstoßventilanordnung für ein Flaschenaufsatzgerät
DE102015000902A1 (de) 2015-01-23 2016-07-28 Brand Gmbh + Co Kg Ausstoßleitungsanordnung für ein Flaschenaufsatzgerät
DE102015000904A1 (de) 2015-01-23 2016-07-28 Brand Gmbh + Co Kg Ventilblockanordnung für ein Flaschenaufsatzgerät
DE102015017471B3 (de) 2015-01-23 2023-07-20 Brand Gmbh + Co Kg Aussstoßleitungsanordnung für ein Flaschenaufsatzgerät

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CN111921576A (zh) * 2020-08-18 2020-11-13 北京沄汇智能科技有限公司 快速装拆多功能物料瓶
CN114889964B (zh) * 2022-05-17 2023-09-19 江南大学 一种多用途气液混合增压瓶

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DE202015000522U1 (de) 2015-01-23 2016-04-26 Brand Gmbh + Co Kg Zylinder-Kolben-Anordnung für ein Flaschenaufsatzgerät
DE202015000519U1 (de) 2015-01-23 2016-04-27 Brand Gmbh + Co Kg Ausstoßleitungsanordnung für ein Flaschenaufsatzgerät
DE202015000523U1 (de) 2015-01-23 2016-04-27 Brand Gmbh + Co Kg Ausstoßleitungsanordnung für ein Flaschenaufsatzgerät
DE202015000520U1 (de) 2015-01-23 2016-04-28 Brand Gmbh + Co Kg Ventilblockanordnung für ein Flaschenaufsatzgerät
DE202015000521U1 (de) 2015-01-23 2016-04-28 Brand Gmbh + Co Kg Ausstoßventilanordnung für ein Flaschenaufsatzgerät
EP3048081A1 (fr) 2015-01-23 2016-07-27 Brand GmbH + Co KG Systeme de bloc de soupapes pour un appareil de fixation de bouteille
DE102015000905A1 (de) 2015-01-23 2016-07-28 Brand Gmbh + Co Kg Zylinder-Kolben-Anordnung für ein Flaschenaufsatzgerät
DE102015000903A1 (de) 2015-01-23 2016-07-28 Brand Gmbh + Co Kg Ausstoßleitungsanordnung für ein Flaschenaufsatzgerät
DE102015000906A1 (de) 2015-01-23 2016-07-28 Brand Gmbh + Co Kg Ausstoßventilanordnung für ein Flaschenaufsatzgerät
DE102015000902A1 (de) 2015-01-23 2016-07-28 Brand Gmbh + Co Kg Ausstoßleitungsanordnung für ein Flaschenaufsatzgerät
DE102015000904A1 (de) 2015-01-23 2016-07-28 Brand Gmbh + Co Kg Ventilblockanordnung für ein Flaschenaufsatzgerät
CN105819088A (zh) * 2015-01-23 2016-08-03 普兰德有限两合公司 用于瓶罩器的阀体装置
CN105819087A (zh) * 2015-01-23 2016-08-03 普兰德有限两合公司 用于瓶罩器的柱体活塞装置
CN105819087B (zh) * 2015-01-23 2019-07-30 普兰德有限两合公司 用于瓶罩器的柱体活塞装置
CN105819088B (zh) * 2015-01-23 2019-07-30 普兰德有限两合公司 用于瓶罩器的阀体装置
DE102015000903B4 (de) 2015-01-23 2023-05-17 Brand Gmbh + Co Kg Ausstoßleitungsanordnungen für ein Flaschenaufsatzgerät
DE102015000902B4 (de) 2015-01-23 2023-06-15 Brand Gmbh + Co Kg Ausstoßleitungsanordnung für ein Flaschenaufsatzgerät
DE102015017471B3 (de) 2015-01-23 2023-07-20 Brand Gmbh + Co Kg Aussstoßleitungsanordnung für ein Flaschenaufsatzgerät

Also Published As

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EP2125223A2 (fr) 2009-12-02
EP2799141A3 (fr) 2015-01-21
US20100021349A1 (en) 2010-01-28
CN103285951B (zh) 2015-01-14
WO2008068013A2 (fr) 2008-06-12
US8142738B2 (en) 2012-03-27
EP2125223B1 (fr) 2015-12-02
EP3508274B1 (fr) 2024-02-28
EP3508274A1 (fr) 2019-07-10
CN103285951A (zh) 2013-09-11
WO2008068013A3 (fr) 2008-09-18
EP2799141B1 (fr) 2019-05-01

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