EP0083617A1 - Appareil pour la mesure du temps de coagulation du sang et procede pour saisir et mesurer le temps - Google Patents

Appareil pour la mesure du temps de coagulation du sang et procede pour saisir et mesurer le temps

Info

Publication number
EP0083617A1
EP0083617A1 EP82902153A EP82902153A EP0083617A1 EP 0083617 A1 EP0083617 A1 EP 0083617A1 EP 82902153 A EP82902153 A EP 82902153A EP 82902153 A EP82902153 A EP 82902153A EP 0083617 A1 EP0083617 A1 EP 0083617A1
Authority
EP
European Patent Office
Prior art keywords
measuring
light
cuvette
block
microprocessor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP82902153A
Other languages
German (de)
English (en)
Inventor
Siegfried Jochimsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19813127560 external-priority patent/DE3127560A1/de
Priority claimed from DE3145692A external-priority patent/DE3145692C3/de
Application filed by Individual filed Critical Individual
Publication of EP0083617A1 publication Critical patent/EP0083617A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4905Determining clotting time of blood
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/452Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/40Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
    • B01F35/42Clamping or holding arrangements for mounting receptacles on mixing devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/82Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials

Abstract

L'appareil comprend une cuvette de mesure faisant partie d'un bloc de mesure pouvant être maintenu à une température modérée, un dispositif d'agitation, un dispositif optique de mesure de la turbidité. Il présente une combinaison des caractères suivants: Le dispositif d'agitation (16) est du type magnétique en soi connu; il est placé dans le bloc de mesure (11), au-dessous du canal (8) de réception de la cuvette de mesure (17). Un agitateur, constitué par une bille de métal (23), est disposé dans la cuvette de mesure (17). Il est mis en mouvement par effet magnétique au moyen du dispositif d'agitation (16). La cuvette de mesure (17) est maintenue dans le canal de mesure (8) au moyen d'un dispositif de blocage (18). Elle est disposée dans la trajectoire du faisceau lumineux (32) d'un dispositif de détection optique (13) dont la source de lumière (15) est alimentée par une tension de service au moins égale à la moitié de la tension nominale. Le récepteur de lumière (14) est relié à un indicateur de la valeur mesurée (27). Le bloc de mesure à température modérée peut aussi comprendre un bloc de cuvettes amovible (39) muni de plusieurs canaux (8, 8a) pour plusieurs cuvettes de mesure (17). A chaque cuvette de mesure (17) disposée dans son canal (8a) est associé un détecteur particulier du dispositif de détection optique (13). Celui-ci est relié à un microprocesseur (43) ou analogue, pouvant être actioné au moyen d'un organe de commande (44) et qui est relié à un dispositif de sortie des données. Ce dispositif de sortie des données peut être une imprimante (31) et/ou un écran d'affichage (46).
EP82902153A 1981-07-11 1982-07-02 Appareil pour la mesure du temps de coagulation du sang et procede pour saisir et mesurer le temps Withdrawn EP0083617A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19813127560 DE3127560A1 (de) 1981-07-11 1981-07-11 Geraet zum erfassen und messen der blutgerinnungszeit mit einem zur aufnahme der messkuevette dienenden temperierbaren metallblock, einer ruehreinrichtung und einer lichtoptischen truebungsmesseinrichtung
DE3127560 1981-07-11
DE3145692A DE3145692C3 (de) 1981-11-19 1981-11-19 Verfahren zum Erfassen und Messen der Blutgerinnungszeit und Gerät zur Durchführung des Verfahrens
DE3145692 1981-11-19

Publications (1)

Publication Number Publication Date
EP0083617A1 true EP0083617A1 (fr) 1983-07-20

Family

ID=25794533

Family Applications (1)

Application Number Title Priority Date Filing Date
EP82902153A Withdrawn EP0083617A1 (fr) 1981-07-11 1982-07-02 Appareil pour la mesure du temps de coagulation du sang et procede pour saisir et mesurer le temps

Country Status (4)

Country Link
US (1) US4876069A (fr)
EP (1) EP0083617A1 (fr)
JP (1) JPS58501096A (fr)
WO (1) WO1983000228A1 (fr)

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DE3837078A1 (de) * 1988-10-31 1990-05-03 Holger Behnk Verfahren und vorrichtung zum untersuchen und messen der blutgerinnungszeit
US5007740A (en) * 1989-03-30 1991-04-16 The Foxboro Company Optical probe for fluid light transmission properties
DE4113330A1 (de) * 1991-04-24 1992-10-29 Amelung Gmbh Heinrich Vorrichtung zur photometrischen bestimmung des gerinnungsverhaltens von blut, blutplasma oder dergleichen
DE4117583A1 (de) * 1991-05-29 1992-12-03 Helmut Prof Dr Orth Geraet zur messung der blutsenkung
US5314826A (en) * 1991-08-23 1994-05-24 Medtronic Hemotec, Inc. Platelet activation and function evaluation technique
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US5222808A (en) * 1992-04-10 1993-06-29 Biotrack, Inc. Capillary mixing device
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US5629209A (en) * 1995-10-19 1997-05-13 Braun, Sr.; Walter J. Method and apparatus for detecting viscosity changes in fluids
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US5925319A (en) 1996-04-30 1999-07-20 Medtronic, Inc. Test cartridge for evaluating blood platelet functionality
AU6681298A (en) * 1997-03-05 1998-09-22 Diametrics Method and apparatus for measurement of whole blood coagulation parameters
US6177283B1 (en) * 1997-05-28 2001-01-23 Flexsite Diagnostics, Inc. Diagnostic assay
US6265223B1 (en) 1997-05-28 2001-07-24 Flexsite Diagnostics, Inc. Diagnostic assay
US5899567A (en) * 1997-09-23 1999-05-04 Morris, Jr.; Joseph E. Magnetic synchronized stirring and heating test apparatus
EP0970742A3 (fr) * 1998-07-09 2002-01-23 Ral Tecnica para el Laboratorio, S.A. Dispositif d'agitation amélioré
US6382827B1 (en) * 2000-11-01 2002-05-07 Dade Behring Inc. Method and apparatus for mixing liquid solutions using a rotating magnet to generate a stirring vortex action
US6467946B1 (en) * 2001-04-24 2002-10-22 Dade Microscan Inc. Method and apparatus for mixing liquid samples in a container using rotating magnetic fields
JP4334171B2 (ja) * 2001-12-03 2009-09-30 シスメックス株式会社 血液凝固反応解析方法
DE50204937D1 (de) * 2002-02-14 2005-12-22 Emz Hanauer Gmbh & Co Kgaa Trübungssensoren mit angepasster Übertragungscharakteristik und Verfahren zum Herstellen derselben
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EP2770318B1 (fr) 2013-02-21 2018-03-21 Roche Diagniostics GmbH Procédé et appareil de détection de caillots dans un liquide et système d'automatisation de laboratoire
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Also Published As

Publication number Publication date
US4876069A (en) 1989-10-24
WO1983000228A1 (fr) 1983-01-20
JPH0246110B2 (fr) 1990-10-12
JPS58501096A (ja) 1983-07-07

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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AK Designated contracting states

Designated state(s): FR

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 19830919