EE200300188A - Reumatoidartriidi raviks kasutatavad EP4 retseptori inhibiitorid - Google Patents
Reumatoidartriidi raviks kasutatavad EP4 retseptori inhibiitoridInfo
- Publication number
- EE200300188A EE200300188A EEP200300188A EEP200300188A EE200300188A EE 200300188 A EE200300188 A EE 200300188A EE P200300188 A EEP200300188 A EE P200300188A EE P200300188 A EEP200300188 A EE P200300188A EE 200300188 A EE200300188 A EE 200300188A
- Authority
- EE
- Estonia
- Prior art keywords
- treatment
- rheumatoid arthritis
- receptor inhibitors
- inhibitors
- receptor
- Prior art date
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
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US24182500P | 2000-10-19 | 2000-10-19 | |
PCT/IB2001/001942 WO2002032422A2 (fr) | 2000-10-19 | 2001-10-15 | Inhibiteurs du recepteur ep4 destines au traitement de la polyarthrite rhumatoide |
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EEP200300188A EE200300188A (et) | 2000-10-19 | 2001-10-15 | Reumatoidartriidi raviks kasutatavad EP4 retseptori inhibiitorid |
EEP200300190A EE200300190A (et) | 2000-10-19 | 2001-10-15 | Arüül- või heteroarüülkondenseerunud imidasooliühendid põletikuvastaste ja analgeetiliste ainetena |
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EP4364798A3 (fr) | 2018-10-05 | 2024-06-19 | Annapurna Bio Inc. | Composés et compositions pour le traitement d'états associés à l'activité du récepteur apj |
WO2020160075A1 (fr) | 2019-01-30 | 2020-08-06 | Avista Pharma Solutions, Inc. | Composés chimiques |
CA3128346A1 (fr) | 2019-01-30 | 2020-08-06 | Avista Pharma Solutions, Inc. | Procede de synthese et nouveaux intermediaires |
WO2021027722A1 (fr) * | 2019-08-09 | 2021-02-18 | 成都先导药物开发股份有限公司 | Immunomodulateur |
US11254675B2 (en) | 2019-08-12 | 2022-02-22 | Cadila Healthcare Limited | Process for preparation of grapiprant |
WO2021226162A1 (fr) | 2020-05-05 | 2021-11-11 | Arrys Therapeutics, Inc. | Antagonistes de l'ep4 et leur utilisation dans le traitement des maladies prolifératives" |
TW202228674A (zh) | 2020-11-13 | 2022-08-01 | 日商小野藥品工業股份有限公司 | 藉由併用ep4拮抗藥與免疫檢查點抑制物質而進行之癌症治療 |
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GB8804439D0 (en) * | 1988-02-25 | 1988-03-23 | Pfizer Ltd | Dihydropyridines |
IL94805A (en) | 1989-06-28 | 1994-04-12 | Ciba Geigy Ag | Certain translocated carboxylic acids (a) Arylsulfonamide - and pyridyl - or imidazolil (), process for their preparation and pharmaceutical preparations containing them |
GB9009469D0 (en) * | 1990-04-27 | 1990-06-20 | British Bio Technology | Compounds |
GB9010404D0 (en) * | 1990-05-09 | 1990-06-27 | Pfizer Ltd | Therapeutic agents |
GB2330307A (en) * | 1998-02-07 | 1999-04-21 | Glaxo Group Ltd | EP4 Receptor antagonists as bone resorption inhibitors |
WO1999047497A2 (fr) * | 1998-03-13 | 1999-09-23 | Merck Frosst Canada & Co. | Acides carboxyliques et acylsulfonamides, compositions contenant ces composes et methodes de traitement |
WO2000021542A1 (fr) * | 1998-10-15 | 2000-04-20 | Merck & Co., Inc. | Methodes de stimulation de la formation osseuse |
EP1148877A4 (fr) * | 1998-10-15 | 2003-01-22 | Merck & Co Inc | Inhibition de la resorption osseuse |
JP2000191615A (ja) * | 1998-10-20 | 2000-07-11 | Takeda Chem Ind Ltd | 芳香族アミン誘導体、その製造法および剤 |
WO2000064880A1 (fr) | 1999-04-22 | 2000-11-02 | Synaptic Pharmaceutical Corporation | Antagonistes selectifs npy (y5) |
ES2287016T3 (es) | 1999-04-28 | 2007-12-16 | Sanofi-Aventis Deutschland Gmbh | Derivados de diaril-acido como ligandos del receptor ppar. |
GB0031302D0 (en) | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Napthalene derivatives |
GB0031315D0 (en) | 2000-12-21 | 2001-02-07 | Glaxo Group Ltd | Indole derivatives |
GB0031295D0 (en) | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Naphthalene derivatives |
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