EE05064B1 - Meetod tuntud tetrasooli derivaadi snteesiks - Google Patents
Meetod tuntud tetrasooli derivaadi snteesiksInfo
- Publication number
- EE05064B1 EE05064B1 EEP200200460A EEP200200460A EE05064B1 EE 05064 B1 EE05064 B1 EE 05064B1 EE P200200460 A EEP200200460 A EE P200200460A EE P200200460 A EEP200200460 A EE P200200460A EE 05064 B1 EE05064 B1 EE 05064B1
- Authority
- EE
- Estonia
- Prior art keywords
- compound
- formula
- reaction mixture
- synthesis
- tetrazole derivative
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 150000003536 tetrazoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- 239000011541 reaction mixture Substances 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 239000000010 aprotic solvent Substances 0.000 abstract 1
- 239000003586 protic polar solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0001618A HU222773B1 (hu) | 2000-04-21 | 2000-04-21 | Eljárás egy ismert tetrazolszármazék előállítására |
PCT/HU2001/000047 WO2001081336A1 (en) | 2000-04-21 | 2001-04-20 | Process for the synthesis of a known tetrazol derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
EE200200460A EE200200460A (et) | 2003-12-15 |
EE05064B1 true EE05064B1 (et) | 2008-08-15 |
Family
ID=89978280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP200200460A EE05064B1 (et) | 2000-04-21 | 2001-04-20 | Meetod tuntud tetrasooli derivaadi snteesiks |
Country Status (17)
Country | Link |
---|---|
US (1) | US6710183B2 (xx) |
EP (1) | EP1274702B1 (xx) |
JP (1) | JP2003531203A (xx) |
AT (1) | ATE259366T1 (xx) |
AU (1) | AU2001254998A1 (xx) |
BG (1) | BG65699B1 (xx) |
CZ (1) | CZ301029B6 (xx) |
DE (1) | DE60102008T2 (xx) |
EA (1) | EA004633B1 (xx) |
EE (1) | EE05064B1 (xx) |
ES (1) | ES2215130T3 (xx) |
HU (1) | HU222773B1 (xx) |
PL (1) | PL198664B1 (xx) |
SK (1) | SK286740B6 (xx) |
TR (1) | TR200401058T4 (xx) |
UA (1) | UA72803C2 (xx) |
WO (1) | WO2001081336A1 (xx) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1294712A1 (en) * | 2001-05-18 | 2003-03-26 | Aurobindo Pharma Limited | Process for the crystallization of losartan potassium |
ES2259412T3 (es) * | 2002-04-29 | 2006-10-01 | Teva Pharmaceutical Industries Ltd. | Procedimientos para la preparacion de losartan y losartan potasico. |
AU2003278422A1 (en) * | 2002-10-31 | 2004-05-25 | Ranbaxy Laboratories Limited | Amorphous form of losartan potassium |
WO2004087691A1 (en) * | 2003-04-03 | 2004-10-14 | Ipca Laboratories Limited | A process for the synthesis of losartan potassium |
US6916935B2 (en) * | 2003-05-06 | 2005-07-12 | Ipca Laboratories | Losartan potassium synthesis |
US7345071B2 (en) | 2003-05-07 | 2008-03-18 | Ipca Laboratories Limited | Process for the synthesis of Losartan potassium |
EP1709034A2 (en) * | 2004-01-06 | 2006-10-11 | IPCA Laboratories Limited | An improved process for the synthesis of losartan potassium |
WO2006050922A1 (en) | 2004-11-11 | 2006-05-18 | Lek Pharmaceuticals D.D. | Process for the synthesis of tetrazoles |
ITTO20060560A1 (it) * | 2006-07-27 | 2008-01-28 | S I M S S R L | Composti intermedi per la preparazione di antagonisti dell¿angiotensina ii |
NZ574905A (en) * | 2006-08-22 | 2011-12-22 | Ranbaxy Lab Ltd | Matrix metalloproteinase inhibitors |
WO2018002673A1 (en) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
US11327065B1 (en) * | 2021-08-27 | 2022-05-10 | Jubilant Generics Limited | Preparation of angiotensin receptor blockers or pharmaceutically acceptable salts thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1338238C (en) * | 1988-01-07 | 1996-04-09 | David John Carini | Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids |
DE4224133A1 (de) * | 1992-07-22 | 1994-01-27 | Thomae Gmbh Dr K | Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
DE4221583A1 (de) * | 1991-11-12 | 1993-05-13 | Bayer Ag | Substituierte biphenylpyridone |
DE69233734D1 (de) * | 1991-11-18 | 2008-06-26 | Du Pont | 2-(2'-Triphenylmethyl-2'H-tetrazol-5'-yl)phenylborsäure als Zwischenprodukt zur Synthese von A II Receptorenantagonisten |
US5206374A (en) * | 1991-11-18 | 1993-04-27 | E. I. Du Pont De Nemours And Company | Process for preparing tetrazolylphenylboronic acid intermediates |
EP0736021A4 (en) * | 1993-12-23 | 1997-04-02 | Merck & Co Inc | LOSARTANE POLYMORPHS AND PROCESS FOR THE PREPARATION OF FORM II OF LOSARTANE |
AU696868B2 (en) * | 1994-03-29 | 1998-09-17 | Merck & Co., Inc. | Treatment of atherosclerosis with angiotensin II receptor blocking imidazoles |
ES2105939B1 (es) * | 1994-08-02 | 1998-07-01 | Uriach & Cia Sa J | Nuevos pirazoles con actividad antagonista de la angiotensina ii. |
-
2000
- 2000-04-21 HU HU0001618A patent/HU222773B1/hu active IP Right Grant
-
2001
- 2001-04-20 EA EA200201122A patent/EA004633B1/ru not_active IP Right Cessation
- 2001-04-20 DE DE60102008T patent/DE60102008T2/de not_active Expired - Fee Related
- 2001-04-20 AT AT01928134T patent/ATE259366T1/de not_active IP Right Cessation
- 2001-04-20 WO PCT/HU2001/000047 patent/WO2001081336A1/en active IP Right Grant
- 2001-04-20 SK SK1289-2002A patent/SK286740B6/sk not_active IP Right Cessation
- 2001-04-20 EE EEP200200460A patent/EE05064B1/xx not_active IP Right Cessation
- 2001-04-20 PL PL356929A patent/PL198664B1/pl not_active IP Right Cessation
- 2001-04-20 CZ CZ20023000A patent/CZ301029B6/cs not_active IP Right Cessation
- 2001-04-20 AU AU2001254998A patent/AU2001254998A1/en not_active Abandoned
- 2001-04-20 JP JP2001578426A patent/JP2003531203A/ja active Pending
- 2001-04-20 ES ES01928134T patent/ES2215130T3/es not_active Expired - Lifetime
- 2001-04-20 EP EP01928134A patent/EP1274702B1/en not_active Expired - Lifetime
- 2001-04-20 UA UA2002119212A patent/UA72803C2/uk unknown
- 2001-04-20 TR TR2004/01058T patent/TR200401058T4/xx unknown
- 2001-04-20 US US10/182,109 patent/US6710183B2/en not_active Expired - Fee Related
-
2002
- 2002-08-23 BG BG107031A patent/BG65699B1/bg unknown
Also Published As
Publication number | Publication date |
---|---|
EP1274702A1 (en) | 2003-01-15 |
DE60102008D1 (de) | 2004-03-18 |
SK286740B6 (sk) | 2009-04-06 |
EP1274702B1 (en) | 2004-02-11 |
PL356929A1 (en) | 2004-07-12 |
PL198664B1 (pl) | 2008-07-31 |
ES2215130T3 (es) | 2004-10-01 |
US20030078435A1 (en) | 2003-04-24 |
HU222773B1 (hu) | 2003-10-28 |
WO2001081336A8 (en) | 2002-08-29 |
UA72803C2 (en) | 2005-04-15 |
BG107031A (en) | 2003-08-29 |
CZ301029B6 (cs) | 2009-10-14 |
HU0001618D0 (en) | 2000-06-28 |
BG65699B1 (bg) | 2009-07-31 |
US6710183B2 (en) | 2004-03-23 |
WO2001081336A1 (en) | 2001-11-01 |
SK12892002A3 (sk) | 2002-12-03 |
TR200401058T4 (tr) | 2004-06-21 |
ATE259366T1 (de) | 2004-02-15 |
EA200201122A1 (ru) | 2003-04-24 |
JP2003531203A (ja) | 2003-10-21 |
DE60102008T2 (de) | 2004-12-09 |
EA004633B1 (ru) | 2004-06-24 |
EE200200460A (et) | 2003-12-15 |
AU2001254998A1 (en) | 2001-11-07 |
HUP0001618A2 (hu) | 2002-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB4A | Valid patent at the end of a year |
Effective date: 20081231 |
|
KB4A | Valid patent at the end of a year |
Effective date: 20101231 |
|
MM4A | Lapsed by not paying the annual fees |
Effective date: 20120420 |