DK1567510T3 - Fremgangsmåde til fremstilling af salte af tolperison - Google Patents

Fremgangsmåde til fremstilling af salte af tolperison

Info

Publication number
DK1567510T3
DK1567510T3 DK03812092T DK03812092T DK1567510T3 DK 1567510 T3 DK1567510 T3 DK 1567510T3 DK 03812092 T DK03812092 T DK 03812092T DK 03812092 T DK03812092 T DK 03812092T DK 1567510 T3 DK1567510 T3 DK 1567510T3
Authority
DK
Denmark
Prior art keywords
tolperisone
salts
preparation
acid
addition salt
Prior art date
Application number
DK03812092T
Other languages
English (en)
Inventor
Laszlo Czollner
Beate Kaelz
Jan Rothenburger
Stefan Welzig
Original Assignee
Sanochemia Pharmazeutika Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanochemia Pharmazeutika Ag filed Critical Sanochemia Pharmazeutika Ag
Application granted granted Critical
Publication of DK1567510T3 publication Critical patent/DK1567510T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DK03812092T 2002-12-05 2003-03-31 Fremgangsmåde til fremstilling af salte af tolperison DK1567510T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0182302A AT413539B (de) 2002-12-05 2002-12-05 Verfahren zum herstellen von salzen des tolperison
PCT/AT2003/000092 WO2004050648A1 (de) 2002-12-05 2003-03-31 Verfahren zum herstellen von salzen des tolperison

Publications (1)

Publication Number Publication Date
DK1567510T3 true DK1567510T3 (da) 2007-04-02

Family

ID=32398619

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03812092T DK1567510T3 (da) 2002-12-05 2003-03-31 Fremgangsmåde til fremstilling af salte af tolperison

Country Status (15)

Country Link
US (2) US7385060B2 (da)
EP (1) EP1567510B1 (da)
AT (2) AT413539B (da)
AU (1) AU2003227075A1 (da)
CA (1) CA2507691C (da)
DE (1) DE50306068D1 (da)
DK (1) DK1567510T3 (da)
ES (1) ES2275140T3 (da)
HK (1) HK1085199A1 (da)
HR (1) HRP20050501A2 (da)
MX (1) MXPA05005571A (da)
NO (1) NO20053176L (da)
PL (1) PL378082A1 (da)
PT (1) PT1567510E (da)
WO (1) WO2004050648A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT413539B (de) * 2002-12-05 2006-03-15 Sanochemia Pharmazeutika Ag Verfahren zum herstellen von salzen des tolperison
DE102005014080B4 (de) * 2005-03-21 2007-11-22 Birds Pharma Gmbh Berolina Innovative Research & Development Services Additionssalze des Tolperison, Verfahren zu deren Herstellung, Verwendung derselben und diese enthaltende Arzneimittel
AT505225A1 (de) * 2007-04-26 2008-11-15 Sanochemia Pharmazeutika Ag 0erfahren zur herstellung von hoch reinem 2,4'-dimethyl-3-piperidino-propiophenon (tolperison), dieses enthaltende pharmazeutische zusammensetzungen, sowie tolperison enthaltende wirkstoffformulierungen
US20100249423A1 (en) * 2009-03-09 2010-09-30 Sanochemia Pharmazeutika Ag Tolperisone controlled release tablet
CN107868065B (zh) * 2017-10-19 2021-05-18 湖北美林药业有限公司 一种盐酸托哌酮化合物及其制备方法
CN116253699A (zh) * 2021-12-09 2023-06-13 广州白云山汉方现代药业有限公司 一种盐酸托哌酮新晶型及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5295674A (en) 1976-02-09 1977-08-11 Nippon Carbide Ind Co Ltd Preparation of 4#-substituted-2-methyl-2-piperidinopropiophenone and i ts salts
AT413539B (de) * 2002-12-05 2006-03-15 Sanochemia Pharmazeutika Ag Verfahren zum herstellen von salzen des tolperison

Also Published As

Publication number Publication date
US20060041141A1 (en) 2006-02-23
ES2275140T3 (es) 2007-06-01
PL378082A1 (pl) 2006-02-20
NO20053176D0 (no) 2005-06-28
HRP20050501A2 (en) 2005-08-31
US20080188522A1 (en) 2008-08-07
ATA18232002A (de) 2005-08-15
PT1567510E (pt) 2007-02-28
AU2003227075A1 (en) 2004-06-23
EP1567510B1 (de) 2006-12-20
EP1567510A1 (de) 2005-08-31
NO20053176L (no) 2005-09-05
MXPA05005571A (es) 2005-10-18
WO2004050648A1 (de) 2004-06-17
ATE348821T1 (de) 2007-01-15
HK1085199A1 (en) 2006-08-18
DE50306068D1 (de) 2007-02-01
CA2507691A1 (en) 2004-06-17
CA2507691C (en) 2010-10-12
AT413539B (de) 2006-03-15
US7385060B2 (en) 2008-06-10

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