CO4700282A1 - Compuestos - Google Patents
CompuestosInfo
- Publication number
- CO4700282A1 CO4700282A1 CO95062409A CO95062409A CO4700282A1 CO 4700282 A1 CO4700282 A1 CO 4700282A1 CO 95062409 A CO95062409 A CO 95062409A CO 95062409 A CO95062409 A CO 95062409A CO 4700282 A1 CO4700282 A1 CO 4700282A1
- Authority
- CO
- Colombia
- Prior art keywords
- formula
- single enantiomer
- enantiomer
- enantiomers
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
- C07C211/41—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
- C07C211/42—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Un enantiomero simple de la Fórmula (I):o una sal de la misma.Un proceso para preparar un enantiómero simple de la Fórmula (I) que comprende:(A) obtener un enantiómero simple de la Fórmula (I) de una mezcla correspondiente de enantiómeros por:(i) Separación de una mezcla de enantiómeros de la Fórmula (I) o un derivado de la misma mediante cromatrografia.(ii) Separación de diastereoisómeros de un derivado quiral de una mezcla de los enantiómeros de la Fórmula (I).(B) Desprotección de un enantiómero simple de la Fórmula (II)donde Alk es un grupo C1-4 alquilo, como etilo, o t-butilo;(C) Reducción de un enantiomero simple de la Fórmula (III).donde Alk es un grupo C1-4 alquilo, como metilo o etilo; seguido, si fuere necesario o aconsejable por la conversión de un derivado de un enantiomero de la Fórmula (I) así obtenida en un enantiómero de la Fórmula (I) en sí; conversión de una sal en la base libre y/o formación de sal.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9500691.2A GB9500691D0 (en) | 1995-01-13 | 1995-01-13 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4700282A1 true CO4700282A1 (es) | 1998-12-29 |
Family
ID=10768011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO95062409A CO4700282A1 (es) | 1995-01-13 | 1995-12-29 | Compuestos |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5863952A (es) |
| EP (1) | EP0802899A1 (es) |
| JP (1) | JPH10512252A (es) |
| AU (1) | AU4537596A (es) |
| CO (1) | CO4700282A1 (es) |
| GB (1) | GB9500691D0 (es) |
| IL (1) | IL116734A0 (es) |
| MA (1) | MA23772A1 (es) |
| WO (1) | WO1996021641A1 (es) |
| ZA (1) | ZA96203B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9518572D0 (en) * | 1995-09-12 | 1995-11-15 | Smithkline Beecham Plc | Compounds |
| US6620848B2 (en) * | 1997-01-13 | 2003-09-16 | Smithkline Beecham Corporation | Nitric oxide synthase inhibitors |
| WO1999043658A1 (en) | 1998-02-27 | 1999-09-02 | Warner-Lambert Company | Heterocyclic substituted aniline calcium channel blockers |
| US6166052A (en) | 1998-03-11 | 2000-12-26 | Warner-Lambert Company | Heteroaryl alkyl alpha substituted peptidylamine calcium channel blockers |
| WO2000021550A2 (en) * | 1998-10-13 | 2000-04-20 | President And Fellows Of Harvard College | Methods and compositions for treating neurodegenerative diseases |
| MY125533A (en) * | 1999-12-06 | 2006-08-30 | Bristol Myers Squibb Co | Heterocyclic dihydropyrimidine compounds |
| US20030045449A1 (en) * | 2001-08-15 | 2003-03-06 | Pfizer, Inc. | Pharmaceutical combinations for the treatment of neurodegenerative diseases |
| CA2421801C (en) * | 2003-03-13 | 2010-02-23 | Denfred Holdings Ltd. | Automatic valve assembly for a water cooler reservoir |
| WO2005037286A1 (en) * | 2003-03-25 | 2005-04-28 | Vasopharm Biotech Gmbh | Use of pteridine derivatives for the treatment of increased intracranial pressure and secondary ischemia |
| CN101018546B (zh) * | 2004-09-10 | 2013-06-12 | 纽朗制药有限公司 | 作为钠和/或钙通道选择性调节剂的(卤代苄氧基)苄氨基-丙酰胺类 |
| NZ567540A (en) | 2005-12-22 | 2010-07-30 | Newron Pharm Spa | 2-Phenylethylamino derivatives as calcium and/or sodium channel modulators |
| PT2155663T (pt) | 2007-06-15 | 2018-01-16 | Newron Pharm Spa | Derivados de 2-[2-(fenil)etilamino]alcanamida substituídos e sua utilização como moduladores dos canais de sódio e/ou de cálcio |
| PL2723710T3 (pl) | 2011-06-27 | 2017-02-28 | Newron Pharmaceuticals S.P.A. | Fluorowane pochodne aryloalkiloaminokarboksyamidowe |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9315600D0 (en) * | 1993-07-28 | 1993-09-08 | Smithkline Beecham Plc | Compounds |
| US5877218A (en) * | 1994-01-10 | 1999-03-02 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives |
-
1995
- 1995-01-13 GB GBGB9500691.2A patent/GB9500691D0/en active Pending
- 1995-12-29 CO CO95062409A patent/CO4700282A1/es unknown
-
1996
- 1996-01-10 MA MA24127A patent/MA23772A1/fr unknown
- 1996-01-10 US US08/860,764 patent/US5863952A/en not_active Expired - Fee Related
- 1996-01-10 EP EP96901302A patent/EP0802899A1/en not_active Ceased
- 1996-01-10 WO PCT/EP1996/000206 patent/WO1996021641A1/en not_active Application Discontinuation
- 1996-01-10 AU AU45375/96A patent/AU4537596A/en not_active Abandoned
- 1996-01-10 JP JP8521453A patent/JPH10512252A/ja active Pending
- 1996-01-11 ZA ZA96203A patent/ZA96203B/xx unknown
- 1996-01-11 IL IL11673496A patent/IL116734A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996021641A1 (en) | 1996-07-18 |
| US5863952A (en) | 1999-01-26 |
| EP0802899A1 (en) | 1997-10-29 |
| MA23772A1 (fr) | 1996-10-01 |
| ZA96203B (en) | 1997-07-11 |
| JPH10512252A (ja) | 1998-11-24 |
| IL116734A0 (en) | 1997-08-14 |
| GB9500691D0 (en) | 1995-03-08 |
| AU4537596A (en) | 1996-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0915866T3 (da) | Forbedret fremgangsmåde til syntese af beskyttende estere af (S)-3,4-dihydroxysmørsyre | |
| CO4700282A1 (es) | Compuestos | |
| FR2446834A1 (fr) | Octahydro-pyrazolo(3,4-g)quinoleines utiles comme intermediaires de synthese | |
| CO4920223A1 (es) | Derivados de 1,3,8-triaza-espiro[4,5]decan-4-ona 8- sustituidos | |
| RS49626B (sr) | Novi postupak za dobijanje farmakološki aktivne supstance | |
| HUP9901658A2 (hu) | Eljárás d-treo- (R,R)-metil-fenidát előállítására, és a nem kívánt enantiomerek visszanyerése epimerizálással | |
| DK0956033T3 (da) | Totalsyntese af amino-Hip-analogen af didemnin A | |
| AR006058A1 (es) | Procedimientos para preparar compuestos de dicianoacetato y de 1,2-pirazol-5-amino-3-substituido | |
| DK0885191T3 (da) | Opspaltning af threo-methylphenidat | |
| DK0787124T3 (da) | Fremgangsmåde til fremstilling af substituerede 3-aminobenzonitriler | |
| FI875596A (fi) | Foerfarande foer framstaellning av tienyletylaminer och aeven ditienyletylaminer. | |
| ES2106936T3 (es) | Derivados de carbazolona y procedimientos para su preparacion. | |
| EA199800354A1 (ru) | Способ получения производных камптотецина | |
| EE05064B1 (et) | Meetod tuntud tetrasooli derivaadi snteesiks | |
| DK0625137T3 (da) | Fremgangsmåde til racematadskillelse af verapamil | |
| EP0713873A3 (en) | Aminocyclopentane derivative | |
| DK1206452T3 (da) | Fremgangsmåde til fremstilling af benzoperhydro-isoindolforbindelser | |
| BR9809143A (pt) | Processo para sintetizar composto | |
| ATE277898T1 (de) | Verfahren zu herstellung von taxol | |
| EA199600007A3 (ru) | Новые трициклические производные, способ их получения, способы получения оптически активных или рацемических колхицина и тиоколхицина, их аналогов или производных с использованием трициклических соединений и промежуточные продукты синтеза | |
| DK1015415T3 (da) | Nye stereoselektive fremgangsmåder til fremstilling af gabapentin-analoger | |
| DK0703237T3 (da) | Fremgangsmåde til fremstilling af thio-phospholipider af ether-typen | |
| AU6675696A (en) | A novel asymmetric synthesis of r and s warfarin and its analogs | |
| BR9908511A (pt) | Processo para a preparação de um composto, e, composto | |
| DE59908860D1 (de) | Verfahren zur Synthese alpha-substituierter Ringsysteme |