ECSP066459A - Miméticos de glucocorticoides, métodos de preparación, composiciones farmacéuticas y usos de los mismos - Google Patents
Miméticos de glucocorticoides, métodos de preparación, composiciones farmacéuticas y usos de los mismosInfo
- Publication number
- ECSP066459A ECSP066459A EC2006006459A ECSP066459A ECSP066459A EC SP066459 A ECSP066459 A EC SP066459A EC 2006006459 A EC2006006459 A EC 2006006459A EC SP066459 A ECSP066459 A EC SP066459A EC SP066459 A ECSP066459 A EC SP066459A
- Authority
- EC
- Ecuador
- Prior art keywords
- pharmaceutical compositions
- glucocorticoids
- mimetics
- same
- preparation methods
- Prior art date
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
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- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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Abstract
Compuestos de Fórmulas (IA), (IB), (IC), y (ID) (IA) (IB) (IC) (ID)en las cuales R1, R2, R3, R4, R5 y R6 son como se definen respectivamente en la presente para las Fórmulas (IA), (IB), (IC) y (ID), o un tautómero, profármaco, solvato o una sal de los mismos; composiciones farmacéuticas que contienen tales compuestos, y métodos para modular la función del receptor de glucocorticoides y métodos para tratar un estado o un cuadro patológico mediado por la función del receptor de glucocorticoides o caracterizado por procesos inflamatorios, alérgicos o proliferativos en un paciente que utiliza estos compuestos.
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-
2004
- 2004-09-20 UY UY28526A patent/UY28526A1/es not_active Application Discontinuation
- 2004-09-21 PE PE2004000917A patent/PE20050951A1/es not_active Application Discontinuation
- 2004-09-21 PE PE2008001805A patent/PE20090217A1/es not_active Application Discontinuation
- 2004-09-21 PE PE2008001807A patent/PE20090219A1/es not_active Application Discontinuation
- 2004-09-21 PE PE2008001806A patent/PE20090218A1/es not_active Application Discontinuation
- 2004-09-22 RS YUP-2006/0201A patent/RS20060201A/sr unknown
- 2004-09-22 AU AU2004275757A patent/AU2004275757B2/en not_active Ceased
- 2004-09-22 CA CA2539909A patent/CA2539909C/en not_active Expired - Fee Related
- 2004-09-22 CN CN2010102426640A patent/CN101948425A/zh active Pending
- 2004-09-22 RU RU2006113696/04A patent/RU2006113696A/ru not_active Application Discontinuation
- 2004-09-22 WO PCT/US2004/031009 patent/WO2005030213A1/en active Application Filing
- 2004-09-22 JP JP2006528127A patent/JP4778430B2/ja not_active Expired - Fee Related
- 2004-09-22 EP EP04788894A patent/EP1673088A1/en not_active Withdrawn
- 2004-09-22 TW TW093128656A patent/TWI340138B/zh not_active IP Right Cessation
- 2004-09-22 KR KR1020067007921A patent/KR101152690B1/ko not_active IP Right Cessation
- 2004-09-22 US US10/947,420 patent/US8741897B2/en active Active
- 2004-09-22 MX MXPA06002880A patent/MXPA06002880A/es not_active Application Discontinuation
- 2004-09-22 SG SG200807363-7A patent/SG146694A1/en unknown
- 2004-09-22 NZ NZ546666A patent/NZ546666A/en not_active IP Right Cessation
- 2004-09-22 BR BRPI0414591-7A patent/BRPI0414591A/pt not_active IP Right Cessation
- 2004-09-23 AR ARP040103429A patent/AR046020A1/es active Pending
-
2006
- 2006-03-21 IL IL174475A patent/IL174475A0/en unknown
- 2006-03-24 EC EC2006006459A patent/ECSP066459A/es unknown
- 2006-04-21 NO NO20061766A patent/NO20061766L/no not_active Application Discontinuation
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2010
- 2010-05-06 JP JP2010106594A patent/JP2010209100A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
PE20090218A1 (es) | 2009-03-28 |
US8741897B2 (en) | 2014-06-03 |
RS20060201A (en) | 2008-08-07 |
MXPA06002880A (es) | 2006-06-05 |
JP2007506750A (ja) | 2007-03-22 |
PE20090219A1 (es) | 2009-03-26 |
AU2004275757B2 (en) | 2011-03-24 |
SG146694A1 (en) | 2008-10-30 |
UY28526A1 (es) | 2005-04-29 |
PE20050951A1 (es) | 2005-12-12 |
US20050176706A1 (en) | 2005-08-11 |
IL174475A0 (en) | 2006-08-01 |
TWI340138B (en) | 2011-04-11 |
RU2006113696A (ru) | 2007-11-20 |
KR20060115858A (ko) | 2006-11-10 |
CA2539909A1 (en) | 2005-04-07 |
EP1673088A1 (en) | 2006-06-28 |
NZ546666A (en) | 2010-02-26 |
JP2010209100A (ja) | 2010-09-24 |
KR101152690B1 (ko) | 2012-07-05 |
AR046020A1 (es) | 2005-11-23 |
WO2005030213A1 (en) | 2005-04-07 |
NO20061766L (no) | 2006-06-21 |
BRPI0414591A (pt) | 2006-11-07 |
JP4778430B2 (ja) | 2011-09-21 |
CN101948425A (zh) | 2011-01-19 |
CA2539909C (en) | 2012-07-31 |
TW200526655A (en) | 2005-08-16 |
PE20090217A1 (es) | 2009-03-26 |
AU2004275757A1 (en) | 2005-04-07 |
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