UY29732A1 - Derivados de benzotiazolonas, procesos de preparación, composiciones y combinaciones que los contienen y aplicaciones - Google Patents
Derivados de benzotiazolonas, procesos de preparación, composiciones y combinaciones que los contienen y aplicacionesInfo
- Publication number
- UY29732A1 UY29732A1 UY29732A UY29732A UY29732A1 UY 29732 A1 UY29732 A1 UY 29732A1 UY 29732 A UY29732 A UY 29732A UY 29732 A UY29732 A UY 29732A UY 29732 A1 UY29732 A1 UY 29732A1
- Authority
- UY
- Uruguay
- Prior art keywords
- benzotiazolonas
- compositions
- derivatives
- applications
- preparation processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención proporciona compuestos de fórmula (I) donde e, r1, R2, r3 ,R4, R5, R4, R5, R6, R7, R7a, R7b, ,D, m y n son como se definió en ela especificación, los procesos para su preparación, las composiciones farmacéuticas que los contienen y su uso en terapia.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0501793 | 2005-08-09 | ||
SE0501914 | 2005-08-30 | ||
SE0600515 | 2006-03-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY29732A1 true UY29732A1 (es) | 2007-03-30 |
Family
ID=37727572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY29732A UY29732A1 (es) | 2005-08-09 | 2006-08-08 | Derivados de benzotiazolonas, procesos de preparación, composiciones y combinaciones que los contienen y aplicaciones |
Country Status (17)
Country | Link |
---|---|
US (2) | US7709511B2 (es) |
EP (1) | EP1915354A4 (es) |
JP (1) | JP4522474B2 (es) |
KR (1) | KR20080033372A (es) |
AR (1) | AR056026A1 (es) |
AU (2) | AU2006277074B2 (es) |
BR (1) | BRPI0614542A2 (es) |
CA (1) | CA2618511C (es) |
EC (1) | ECSP088246A (es) |
IL (1) | IL188857A0 (es) |
MX (1) | MX2008001664A (es) |
MY (1) | MY145647A (es) |
NO (1) | NO20081217L (es) |
NZ (1) | NZ565472A (es) |
TW (1) | TW200738658A (es) |
UY (1) | UY29732A1 (es) |
WO (1) | WO2007018461A1 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200738658A (en) * | 2005-08-09 | 2007-10-16 | Astrazeneca Ab | Novel compounds |
TW200738659A (en) * | 2005-08-29 | 2007-10-16 | Astrazeneca Ab | Novel compounds |
TW200745067A (en) | 2006-03-14 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
TW200825084A (en) | 2006-11-14 | 2008-06-16 | Astrazeneca Ab | New compounds 521 |
US20100056508A1 (en) * | 2006-12-20 | 2010-03-04 | Astrazeneca Ab | Amine derivatives and their use in beta-2-adrenoreceptor mediated diseases |
TW200833670A (en) * | 2006-12-20 | 2008-08-16 | Astrazeneca Ab | Novel compounds 569 |
GB0702385D0 (en) * | 2007-02-07 | 2007-03-21 | Argenta Discovery Ltd | New combination |
GB0702457D0 (en) * | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | New combination 666 |
GB0702458D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | Salts 668 |
GB0702459D0 (en) * | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | Salts 669 |
GB0702456D0 (en) * | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | New combination |
WO2009037503A2 (en) * | 2007-09-18 | 2009-03-26 | Astrazeneca Ab | New combination - 012 for the treatment of respiratory diseases |
EP2300464A1 (en) | 2008-05-13 | 2011-03-30 | AstraZeneca AB | Quinuclidine derivatives as muscarinic m3 receptor antagonists |
JP2011520877A (ja) * | 2008-05-13 | 2011-07-21 | アストラゼネカ・アクチエボラーグ | ムスカリン受容体アンタゴニストおよびβ2−アドレナリン受容体アゴニストを含む医薬品 |
WO2009142568A1 (en) * | 2008-05-20 | 2009-11-26 | Astrazeneca Ab | Combination of (a) glucocorticoid receptor modulator and (b) a b2-agonist |
GB0811100D0 (en) * | 2008-06-17 | 2008-07-23 | Astrazeneca Ab | New combination |
CN102124003A (zh) | 2008-06-18 | 2011-07-13 | 阿斯利康(瑞典)有限公司 | 作为治疗呼吸系统疾病的β2肾上腺素受体拮抗剂的苯并噁嗪酮衍生物 |
AU2009260904A1 (en) * | 2008-06-20 | 2009-12-23 | Astrazeneca Ab | Pharmaceutical composition comprising a 4-hydroxy-2-oxo-2, 3- dihydro-1, 3-benzothiazol-7-yl compound for modulation of beta2-adrenoreceptor activity |
GB0814728D0 (en) * | 2008-08-12 | 2008-09-17 | Argenta Discovery Ltd | New combination |
GB0913342D0 (en) | 2009-07-31 | 2009-09-16 | Astrazeneca Ab | Compounds - 801 |
WO2011061527A1 (en) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases |
WO2012142668A1 (en) | 2011-04-18 | 2012-10-26 | Commonwealth Scientific And Industrial Research Organisation | Gas capture process |
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US4460581A (en) | 1982-10-12 | 1984-07-17 | Boehringer Ingelheim Kg | (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones |
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US4554287A (en) | 1984-09-12 | 1985-11-19 | Smithkline Beckman Corporation | Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones |
US4554284A (en) | 1984-09-12 | 1985-11-19 | Smithkline Beckman Corporation | 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones |
GB8525483D0 (en) | 1985-10-16 | 1985-11-20 | Glaxo Group Ltd | Chemical compounds |
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JPH03133946A (ja) | 1989-10-10 | 1991-06-07 | Glaxo Group Ltd | フェンエタノールアミン化合物 |
GB9211172D0 (en) | 1992-05-27 | 1992-07-08 | Fisons Plc | Compounds |
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US5648370A (en) | 1990-11-20 | 1997-07-15 | Astra Pharmaceuticals Limited | 7-(2-aminoethyl) benzothiazolones |
GB9210632D0 (en) | 1992-05-19 | 1992-07-01 | Fisons Plc | Compounds |
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GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
GB9526511D0 (en) | 1995-12-23 | 1996-02-28 | Astra Pharma Prod | Pharmaceutically active compounds |
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WO1997032856A1 (en) | 1996-03-05 | 1997-09-12 | Zeneca Limited | 4-anilinoquinazoline derivatives |
ATE209192T1 (de) | 1996-05-20 | 2001-12-15 | Teijin Ltd | Cyclischer diarylalkyl diaminederivate als antogoniste von chemokinerezeptoren |
GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
SE9700706D0 (sv) | 1997-02-27 | 1997-02-27 | Astra Pharma Prod | Process for the preparation of benzothiazoline compounds |
SE9701304D0 (sv) | 1997-04-09 | 1997-04-09 | Astra Pharma Prod | Compounds |
GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
JP2002509119A (ja) | 1998-01-13 | 2002-03-26 | アストラゼネカ ユーケイ リミテッド | ドーパミン(D2)レセプターアゴニスト活性を有する化合物およびβ2−アドレナリンレセプターアゴニスト活性を有する化合物(B)を含有する薬学的組成物 |
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SE9902935D0 (sv) | 1999-08-18 | 1999-08-18 | Astra Pharma Prod | Pharmaceutical compositions |
SE9902936D0 (sv) | 1999-08-18 | 1999-08-18 | Astra Pharma Prod | Pharmaceutical compositions |
SE9902938D0 (sv) | 1999-08-18 | 1999-08-18 | Astra Pharma Prod | Pharmaceutical compositions |
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PE20050130A1 (es) | 2002-08-09 | 2005-03-29 | Novartis Ag | Compuestos organicos |
GB0225540D0 (en) | 2002-11-01 | 2002-12-11 | Glaxo Group Ltd | Medicinal compounds |
GB0303396D0 (en) | 2003-02-14 | 2003-03-19 | Glaxo Group Ltd | Medicinal compounds |
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JP2005187357A (ja) | 2003-12-25 | 2005-07-14 | Nippon Suisan Kaisha Ltd | 選択的なβ2受容体アゴニスト活性を有するベンゾチアゾロン誘導体の製造方法 |
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WO2005092861A1 (en) | 2004-03-11 | 2005-10-06 | Pfizer Limited | Quinolinone derivatives pharmaceutical compositions containing them and their use |
EP1577306A1 (de) | 2004-03-17 | 2005-09-21 | Boehringer Ingelheim Pharma GmbH & Co.KG | Neue Benzoxazinonderivate als langwirksame Betamimetika zur Behandlung von Atemwegserkrankungen |
WO2005092841A1 (en) | 2004-03-23 | 2005-10-06 | Pfizer Limited | Compounds having beta-agonist activity |
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EP1595873A1 (de) | 2004-05-13 | 2005-11-16 | Boehringer Ingelheim Pharma GmbH & Co.KG | Substituierte Cycloalkylderivate zur Behandlung von Atemswegerkrankungen |
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JP2008507532A (ja) | 2004-07-21 | 2008-03-13 | セラヴァンス, インコーポレーテッド | ジアリールエーテルβ2アドレナリン作用性レセプターアゴニスト |
EP1778626A1 (en) | 2004-08-16 | 2007-05-02 | Theravance, Inc. | Compounds having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity |
WO2006023460A2 (en) | 2004-08-16 | 2006-03-02 | Theravance, Inc. | COMPOUNDS HAVING β2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY |
JP2008512470A (ja) | 2004-09-10 | 2008-04-24 | セラヴァンス, インコーポレーテッド | アミジン置換アリールアニリン化合物 |
GB0426164D0 (en) | 2004-11-29 | 2004-12-29 | Novartis Ag | Organic compounds |
US20080125462A1 (en) | 2005-01-11 | 2008-05-29 | Lois Elizabeth Vernon | Cinnamate Salts Of A Beta-2 Adrenergic Agonist |
GB0511066D0 (en) | 2005-05-31 | 2005-07-06 | Novartis Ag | Organic compounds |
NZ585580A (en) | 2005-07-18 | 2011-08-26 | Pfizer Ltd | Process for the preparation of sulfonamide derivatives |
TW200738658A (en) | 2005-08-09 | 2007-10-16 | Astrazeneca Ab | Novel compounds |
TW200738659A (en) | 2005-08-29 | 2007-10-16 | Astrazeneca Ab | Novel compounds |
TW200740781A (en) | 2005-08-29 | 2007-11-01 | Astrazeneca Ab | Novel compounds |
TW200745084A (en) | 2006-03-08 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
TW200745067A (en) | 2006-03-14 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
WO2008041914A1 (en) | 2006-10-06 | 2008-04-10 | Astrazeneca Ab | 5-(2-AMINO-L-HYDROXYETHYL)-8-HYDROXY-2-OXOQUINOLINE DERIVATIVES AND OTHER COMPOUNDS AS β2 -ADRENERGIC AGONISTS |
TW200833670A (en) | 2006-12-20 | 2008-08-16 | Astrazeneca Ab | Novel compounds 569 |
US20100056508A1 (en) | 2006-12-20 | 2010-03-04 | Astrazeneca Ab | Amine derivatives and their use in beta-2-adrenoreceptor mediated diseases |
GB0702456D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | New combination |
GB0702458D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | Salts 668 |
GB0702459D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | Salts 669 |
GB0702457D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | New combination 666 |
GB0704000D0 (en) | 2007-03-01 | 2007-04-11 | Astrazeneca Ab | Salts 670 |
GB0703999D0 (en) | 2007-03-01 | 2007-04-11 | Astrazeneca Ab | New combination 667 |
WO2009037503A2 (en) | 2007-09-18 | 2009-03-26 | Astrazeneca Ab | New combination - 012 for the treatment of respiratory diseases |
-
2006
- 2006-07-28 TW TW095127717A patent/TW200738658A/zh unknown
- 2006-08-03 JP JP2008525958A patent/JP4522474B2/ja not_active Expired - Fee Related
- 2006-08-03 AU AU2006277074A patent/AU2006277074B2/en not_active Ceased
- 2006-08-03 CA CA2618511A patent/CA2618511C/en not_active Expired - Fee Related
- 2006-08-03 US US12/063,322 patent/US7709511B2/en active Active
- 2006-08-03 NZ NZ565472A patent/NZ565472A/en not_active IP Right Cessation
- 2006-08-03 MX MX2008001664A patent/MX2008001664A/es active IP Right Grant
- 2006-08-03 WO PCT/SE2006/000927 patent/WO2007018461A1/en active Application Filing
- 2006-08-03 EP EP06769596A patent/EP1915354A4/en not_active Withdrawn
- 2006-08-03 BR BRPI0614542-6A patent/BRPI0614542A2/pt not_active IP Right Cessation
- 2006-08-03 KR KR1020087003165A patent/KR20080033372A/ko not_active Application Discontinuation
- 2006-08-07 MY MYPI20063812A patent/MY145647A/en unknown
- 2006-08-08 UY UY29732A patent/UY29732A1/es not_active Application Discontinuation
- 2006-08-09 AR ARP060103492A patent/AR056026A1/es not_active Application Discontinuation
-
2008
- 2008-01-17 IL IL188857A patent/IL188857A0/en unknown
- 2008-03-06 EC EC2008008246A patent/ECSP088246A/es unknown
- 2008-03-07 NO NO20081217A patent/NO20081217L/no not_active Application Discontinuation
-
2010
- 2010-04-27 US US12/768,372 patent/US20100210688A1/en not_active Abandoned
- 2010-06-03 AU AU2010202319A patent/AU2010202319B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
IL188857A0 (en) | 2008-04-13 |
ECSP088246A (es) | 2008-05-30 |
AU2010202319B2 (en) | 2011-09-22 |
AR056026A1 (es) | 2007-09-12 |
NO20081217L (no) | 2008-04-15 |
US7709511B2 (en) | 2010-05-04 |
JP2009504639A (ja) | 2009-02-05 |
CA2618511A1 (en) | 2007-02-15 |
EP1915354A1 (en) | 2008-04-30 |
TW200738658A (en) | 2007-10-16 |
KR20080033372A (ko) | 2008-04-16 |
US20080300275A1 (en) | 2008-12-04 |
US20100210688A1 (en) | 2010-08-19 |
AU2010202319A1 (en) | 2010-07-01 |
MY145647A (en) | 2012-03-15 |
EP1915354A4 (en) | 2010-07-14 |
CA2618511C (en) | 2011-03-15 |
AU2006277074B2 (en) | 2010-03-04 |
AU2006277074A1 (en) | 2007-02-15 |
MX2008001664A (es) | 2008-02-19 |
BRPI0614542A2 (pt) | 2012-11-27 |
NZ565472A (en) | 2011-03-31 |
JP4522474B2 (ja) | 2010-08-11 |
WO2007018461A1 (en) | 2007-02-15 |
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109 | Application deemed to be withdrawn |
Effective date: 20160830 |