AR054347A1 - Combinaciones terapeuticas para el tratamiento o la prevencion de la depresion - Google Patents
Combinaciones terapeuticas para el tratamiento o la prevencion de la depresionInfo
- Publication number
- AR054347A1 AR054347A1 ARP060101594A ARP060101594A AR054347A1 AR 054347 A1 AR054347 A1 AR 054347A1 AR P060101594 A ARP060101594 A AR P060101594A AR P060101594 A ARP060101594 A AR P060101594A AR 054347 A1 AR054347 A1 AR 054347A1
- Authority
- AR
- Argentina
- Prior art keywords
- depression
- treatment
- prevention
- therapeutic combinations
- combinations
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Se proporcionan combinaciones terapéuticas utiles en el tratamiento o prevencion de la depresion u otros trastornos del temperamento, composiciones farmacéuticas que contienen dichas combinaciones, y su uso en el tratamiento o profilaxis de la depresion u otros trastornos del temperamento. Tales compuestos son de formula (1), o una sal farmacéuticamente aceptable de los mismos, donde cada uno de R1, R2, R3, n, y, y Ar son como de definio y describio en la presente.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67404805P | 2005-04-22 | 2005-04-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR054347A1 true AR054347A1 (es) | 2007-06-20 |
Family
ID=36809594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP060101594A AR054347A1 (es) | 2005-04-22 | 2006-04-21 | Combinaciones terapeuticas para el tratamiento o la prevencion de la depresion |
Country Status (13)
Country | Link |
---|---|
US (2) | US7396857B2 (es) |
EP (1) | EP1871355A1 (es) |
JP (1) | JP2008536946A (es) |
CN (1) | CN101198322A (es) |
AR (1) | AR054347A1 (es) |
AU (1) | AU2006239918A1 (es) |
BR (1) | BRPI0610044A2 (es) |
CA (1) | CA2604915A1 (es) |
GT (1) | GT200600163A (es) |
MX (1) | MX2007012882A (es) |
PE (1) | PE20061327A1 (es) |
TW (1) | TW200722081A (es) |
WO (1) | WO2006116149A1 (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
GT200500296A (es) * | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
GT200500297A (es) * | 2004-10-21 | 2006-10-27 | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
PE20061298A1 (es) * | 2005-04-22 | 2006-12-24 | Wyeth Corp | Compuestos derivados de dihidrobenzofurano como agonistas del receptor de serotonina 5-ht2c |
CA2605587A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Chromane and chromene derivatives and uses thereof |
US7470799B2 (en) * | 2005-04-22 | 2008-12-30 | Wyeth | Dihydrobenzofuran derivatives and uses thereof |
CA2605580A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Benzodioxane and benzodioxolane derivatives and uses thereof |
BRPI0610028A2 (pt) * | 2005-04-22 | 2010-05-18 | Wyeth Corp | combinações terapêuticas para o tratamento ou a prevenção de distúrbios psicóticos |
WO2006116151A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Benzofuranyl alkanamine derivatives and uses thereof as 5-ht2c agonists |
JP2008538578A (ja) * | 2005-04-22 | 2008-10-30 | ワイス | 疼痛の治療 |
CA2604759A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Dihydrobenzofuran derivatives and uses thereof |
TW200716106A (en) * | 2005-04-24 | 2007-05-01 | Wyeth Corp | Methods for modulating bladder function |
CL2007000775A1 (es) * | 2006-03-24 | 2008-01-25 | Wyeth Corp | Uso de compuestos derivados de benzofurano para el tratamiento de un desorden cognitivo. |
NZ581707A (en) * | 2007-05-07 | 2011-05-27 | Chelsea Therapeutics Inc | Droxidopa and pharmaceutical composition thereof for the treatment of mood disorders, sleep disorders, or attention deficit disorders |
US8198268B2 (en) | 2008-10-31 | 2012-06-12 | Janssen Biotech, Inc. | Tianeptine sulfate salt forms and methods of making and using the same |
WO2011011594A2 (en) * | 2009-07-23 | 2011-01-27 | Shriners Hospitals For Children | Intracellular toll-like receptors pathways and axonal degeneration |
EP2510949A4 (en) | 2009-12-11 | 2013-11-13 | Astellas Pharma Inc | THERAPEUTICS FOR FIBROMYALGIA |
CN102250048B (zh) * | 2011-06-03 | 2013-06-05 | 浙江工业大学 | 2-苯硒基甲基-2,3-二氢苯并呋喃及其制备与应用 |
CN106716129B (zh) * | 2014-09-26 | 2019-04-19 | 福满代谢组技术有限公司 | 对抑郁症治疗药物的选项进行预测的方法 |
CN113631157A (zh) * | 2019-02-17 | 2021-11-09 | 诺拉威尔治疗公司 | 用于治疗抑郁症和其它病症的组合物和方法 |
Family Cites Families (42)
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US3513239A (en) | 1967-03-15 | 1970-05-19 | Smithkline Corp | Pharmaceutical compositions containing 2-aminoalkyl coumaran derivatives and methods of treating depression therewith |
US3826835A (en) | 1971-01-08 | 1974-07-30 | Ciba Geigy Corp | 8-benzofurylmethyl-1,3,8-triazaspiro(4,5)decanes as neuroleptics |
JPS59186969A (ja) | 1983-04-08 | 1984-10-23 | Yoshitomi Pharmaceut Ind Ltd | ベンゾフラン−およびベンゾピランカルボキサミド誘導体 |
JPH06316563A (ja) | 1993-05-06 | 1994-11-15 | Yoshitomi Pharmaceut Ind Ltd | アミド化合物 |
ES2304041T3 (es) | 1993-06-28 | 2008-09-01 | Wyeth | Nuevos tratamientos que utilizan derivados de fenetilamina. |
US6150402A (en) | 1994-08-15 | 2000-11-21 | Loma Linda University Medical Center | Natriuretic compounds |
AU1106195A (en) | 1994-11-09 | 1996-06-06 | Novo Nordisk A/S | Heterocyclic compounds, their preparation and use |
US5756532A (en) | 1995-11-06 | 1998-05-26 | American Home Products Corporation | Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives |
US6274171B1 (en) | 1996-03-25 | 2001-08-14 | American Home Products Corporation | Extended release formulation of venlafaxine hydrochloride |
DE19909760B4 (de) | 1998-04-17 | 2015-05-21 | Merck Patent Gmbh | Benzofuran-Derivate |
US7045545B1 (en) | 1999-01-27 | 2006-05-16 | Eli Lilly And Company | Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists |
SE9902267D0 (sv) * | 1999-06-16 | 1999-06-16 | Astra Ab | New compounds |
US20020107244A1 (en) | 2001-02-02 | 2002-08-08 | Howard Harry R. | Combination treatment for depression |
US6969730B2 (en) | 2001-03-16 | 2005-11-29 | Abbott Laboratories | Amines as histamine-3 receptor ligands and their therapeutic applications |
KR100446235B1 (ko) | 2001-05-07 | 2004-08-30 | 엘지전자 주식회사 | 다중 후보를 이용한 움직임 벡터 병합 탐색 방법 |
CA2461381A1 (en) | 2001-10-04 | 2003-04-10 | Wyeth | Chroman derivatives as 5-hydroxytryptamine-6 ligands |
WO2003029239A1 (en) | 2001-10-04 | 2003-04-10 | Wyeth | Chroman and benzofuran derivatives as 5-hydroxytryptamine-6 ligands |
US6667322B2 (en) | 2001-10-05 | 2003-12-23 | Wyeth | Antidepressant chroman and chromene derivatives of 3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole |
US20030134835A1 (en) | 2002-01-11 | 2003-07-17 | Arthur Hancock | Histamine-3 receptor ligands for diabetes conditions |
US7208502B2 (en) | 2002-01-18 | 2007-04-24 | Maniv Energy Capital | Methods of treating conditions associated with an Edg-3 receptor |
US20030092770A1 (en) | 2002-10-23 | 2003-05-15 | Phil Skolnick | Combination therapy for treatment of depression |
WO2004089410A1 (ja) | 2003-04-03 | 2004-10-21 | Kyowa Hakko Kogyo Co., Ltd. | 神経因性疼痛の予防及び/または治療剤 |
AU2004259012C1 (en) | 2003-07-23 | 2012-08-02 | Exelixis, Inc. | Anaplastic lymphoma kinase modulators and methods of use |
US20050261347A1 (en) | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
US7728155B2 (en) | 2003-10-24 | 2010-06-01 | Wyeth Llc | Dihydrobenzofuranyl alkanamines and methods for using same as cns agents |
US7435837B2 (en) | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
JPWO2005073210A1 (ja) | 2004-01-28 | 2007-09-06 | キッセイ薬品工業株式会社 | 新規なベンゾフラン誘導体、それを含有する医薬組成物およびそれらの用途 |
DE102004030099A1 (de) | 2004-06-22 | 2006-01-12 | Grünenthal GmbH | Gesättigte und ungesättigte 3-Pyridyl-benzocycloalkylmethyl-amine als Serotonin- und/oder Noradrenalin-Reuptake-Hemmer und/oder µ-Opioidrezeptor-Modulatoren |
WO2006000902A1 (en) | 2004-06-25 | 2006-01-05 | Pfizer Products Inc. | Dihydrobenzofuran compounds and uses thereof |
GT200500296A (es) | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
GT200500297A (es) | 2004-10-21 | 2006-10-27 | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
BRPI0610509A2 (pt) | 2005-04-22 | 2010-06-29 | Wyeth Corp | tratamento de dependência a drogas |
CA2604759A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Dihydrobenzofuran derivatives and uses thereof |
US7470799B2 (en) | 2005-04-22 | 2008-12-30 | Wyeth | Dihydrobenzofuran derivatives and uses thereof |
JP2008538578A (ja) | 2005-04-22 | 2008-10-30 | ワイス | 疼痛の治療 |
PE20061298A1 (es) | 2005-04-22 | 2006-12-24 | Wyeth Corp | Compuestos derivados de dihidrobenzofurano como agonistas del receptor de serotonina 5-ht2c |
WO2006116151A1 (en) | 2005-04-22 | 2006-11-02 | Wyeth | Benzofuranyl alkanamine derivatives and uses thereof as 5-ht2c agonists |
BRPI0610028A2 (pt) * | 2005-04-22 | 2010-05-18 | Wyeth Corp | combinações terapêuticas para o tratamento ou a prevenção de distúrbios psicóticos |
AR055054A1 (es) | 2005-04-22 | 2007-08-01 | Wyeth Corp | Cristales formados de clorhidrato de (((2r)-7-(2,6-diclorofenil)-5-fluoro-2,3- dihidro-1-benzofurano-2-il) metil ) amina |
CA2605587A1 (en) | 2005-04-22 | 2006-11-02 | Wyeth | Chromane and chromene derivatives and uses thereof |
TW200716106A (en) | 2005-04-24 | 2007-05-01 | Wyeth Corp | Methods for modulating bladder function |
CL2007000775A1 (es) | 2006-03-24 | 2008-01-25 | Wyeth Corp | Uso de compuestos derivados de benzofurano para el tratamiento de un desorden cognitivo. |
-
2006
- 2006-04-21 CN CNA2006800218927A patent/CN101198322A/zh active Pending
- 2006-04-21 MX MX2007012882A patent/MX2007012882A/es not_active Application Discontinuation
- 2006-04-21 JP JP2008507943A patent/JP2008536946A/ja active Pending
- 2006-04-21 GT GT200600163A patent/GT200600163A/es unknown
- 2006-04-21 WO PCT/US2006/015191 patent/WO2006116149A1/en active Application Filing
- 2006-04-21 PE PE2006000418A patent/PE20061327A1/es not_active Application Discontinuation
- 2006-04-21 AU AU2006239918A patent/AU2006239918A1/en not_active Abandoned
- 2006-04-21 CA CA002604915A patent/CA2604915A1/en not_active Abandoned
- 2006-04-21 BR BRPI0610044-9A patent/BRPI0610044A2/pt not_active Application Discontinuation
- 2006-04-21 EP EP06769874A patent/EP1871355A1/en not_active Withdrawn
- 2006-04-21 TW TW095114318A patent/TW200722081A/zh unknown
- 2006-04-21 US US11/409,480 patent/US7396857B2/en not_active Expired - Fee Related
- 2006-04-21 AR ARP060101594A patent/AR054347A1/es not_active Application Discontinuation
-
2008
- 2008-05-30 US US12/130,665 patent/US20080269321A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
BRPI0610044A2 (pt) | 2010-05-25 |
JP2008536946A (ja) | 2008-09-11 |
GT200600163A (es) | 2007-03-14 |
US7396857B2 (en) | 2008-07-08 |
PE20061327A1 (es) | 2007-01-02 |
CN101198322A (zh) | 2008-06-11 |
AU2006239918A1 (en) | 2006-11-02 |
TW200722081A (en) | 2007-06-16 |
US20080269321A1 (en) | 2008-10-30 |
CA2604915A1 (en) | 2006-11-02 |
WO2006116149A1 (en) | 2006-11-02 |
EP1871355A1 (en) | 2008-01-02 |
US20060258715A1 (en) | 2006-11-16 |
MX2007012882A (es) | 2007-12-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |