PE20061327A1 - Combinaciones de derivados de benzofurano y un antidepresivo para el tratamiento o la prevencion de la depresion - Google Patents

Combinaciones de derivados de benzofurano y un antidepresivo para el tratamiento o la prevencion de la depresion

Info

Publication number
PE20061327A1
PE20061327A1 PE2006000418A PE2006000418A PE20061327A1 PE 20061327 A1 PE20061327 A1 PE 20061327A1 PE 2006000418 A PE2006000418 A PE 2006000418A PE 2006000418 A PE2006000418 A PE 2006000418A PE 20061327 A1 PE20061327 A1 PE 20061327A1
Authority
PE
Peru
Prior art keywords
benzofuran
antidepressant
depression
prevention
combinations
Prior art date
Application number
PE2006000418A
Other languages
English (en)
Inventor
Janet Jandura
Sharon Rosenzweig-Lipson
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36809594&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20061327(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PE20061327A1 publication Critical patent/PE20061327A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

REFERIDA A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: A) UN COMPUESTO DERIVADO DE BENZOFURANO DE FORMULA (I) Y B) UN ANTIDEPRESIVO; DONDE EN EL COMPUESTO DE FORMULA (I), R1 ES H, HALOGENO, OH, ENTRE OTROS; R2 Y R3 SON H, METILO, ETILO, 2-FLUORETILO ENTRE OTROS; Ar ES TIENILO, FURILO, PIRIDILO, ENTRE OTROS; y ES UN ENTERO DE 0 A 3; n ES 1 O 2. SON COMPUESTOS DE FORMULA (I) PREFERIDOS: (+)-(1-(7-FENIL-2,3-DIHIDRO-1-BENZOFURAN-2-IL)METANAMINA; (+)-1-[7-(3-METILFENIL)-2,3-DIHIDRO-1-BENZOFURAN-2-IL]METANAMINA; (+)-1-(7-TIEN-3-IL-2,3-DIHIDRO-1-BENZOFURAN-2-IL)METANAMINA, ENTRE OTROS. DENTRO DE LOS COMPUESTOS ANTIDEPRESIVOS SE ENCUENTRAN: CLOMIPRAMINA, AMITRIPTILINA, FLUOXETINA, DEANOL, ENTRE OTROS. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE LA DEPRESION U OTROS TRASTORNOS DEL TEMPERAMENTO
PE2006000418A 2005-04-22 2006-04-21 Combinaciones de derivados de benzofurano y un antidepresivo para el tratamiento o la prevencion de la depresion PE20061327A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67404805P 2005-04-22 2005-04-22

Publications (1)

Publication Number Publication Date
PE20061327A1 true PE20061327A1 (es) 2007-01-02

Family

ID=36809594

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2006000418A PE20061327A1 (es) 2005-04-22 2006-04-21 Combinaciones de derivados de benzofurano y un antidepresivo para el tratamiento o la prevencion de la depresion

Country Status (13)

Country Link
US (2) US7396857B2 (es)
EP (1) EP1871355A1 (es)
JP (1) JP2008536946A (es)
CN (1) CN101198322A (es)
AR (1) AR054347A1 (es)
AU (1) AU2006239918A1 (es)
BR (1) BRPI0610044A2 (es)
CA (1) CA2604915A1 (es)
GT (1) GT200600163A (es)
MX (1) MX2007012882A (es)
PE (1) PE20061327A1 (es)
TW (1) TW200722081A (es)
WO (1) WO2006116149A1 (es)

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JP2008538573A (ja) * 2005-04-22 2008-10-30 ワイス ベンゾフラニルアルカナミン誘導体およびその５−ｈｔ２ｃアゴニストとしての使用
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US20060258713A1 (en) * 2005-04-22 2006-11-16 Wyeth Treatment of pain
WO2006116221A2 (en) * 2005-04-22 2006-11-02 Wyeth Therapeutic combinations for the treatment or prevention of psychotic disorders
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EP1871356A1 (en) * 2005-04-22 2008-01-02 Wyeth a Corporation of the State of Delaware Dihydrobenzofuran derivatives and uses thereof
GT200600164A (es) * 2005-04-22 2007-03-14 Derivados de dihidrobenzofuranos y usos de los mismos
AU2006239910A1 (en) * 2005-04-22 2006-11-02 Wyeth Dihydrobenzofuran derivatives and uses thereof
EP1874292A2 (en) * 2005-04-24 2008-01-09 Wyeth Methods for modulating bladder function
WO2007112065A2 (en) * 2006-03-24 2007-10-04 Wyeth Methods for treating cognitive and other disorders
NZ581707A (en) * 2007-05-07 2011-05-27 Chelsea Therapeutics Inc Droxidopa and pharmaceutical composition thereof for the treatment of mood disorders, sleep disorders, or attention deficit disorders
US8198268B2 (en) 2008-10-31 2012-06-12 Janssen Biotech, Inc. Tianeptine sulfate salt forms and methods of making and using the same
WO2011011594A2 (en) * 2009-07-23 2011-01-27 Shriners Hospitals For Children Intracellular toll-like receptors pathways and axonal degeneration
WO2011071136A1 (ja) 2009-12-11 2011-06-16 アステラス製薬株式会社 線維筋痛症治療剤
CN102250048B (zh) * 2011-06-03 2013-06-05 浙江工业大学 2-苯硒基甲基-2,3-二氢苯并呋喃及其制备与应用
KR102118780B1 (ko) * 2014-09-26 2020-06-03 휴먼 메타볼롬 테크놀로지스 가부시키가이샤 우울증 치료약의 선택지를 예측하는 방법
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Also Published As

Publication number Publication date
TW200722081A (en) 2007-06-16
CN101198322A (zh) 2008-06-11
CA2604915A1 (en) 2006-11-02
EP1871355A1 (en) 2008-01-02
AU2006239918A1 (en) 2006-11-02
US20080269321A1 (en) 2008-10-30
BRPI0610044A2 (pt) 2010-05-25
WO2006116149A1 (en) 2006-11-02
AR054347A1 (es) 2007-06-20
US20060258715A1 (en) 2006-11-16
US7396857B2 (en) 2008-07-08
MX2007012882A (es) 2007-12-10
JP2008536946A (ja) 2008-09-11
GT200600163A (es) 2007-03-14

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