MXPA06002880A - Derivados 1,1,1-trifluoro-4-fenil-4-metil-2-(1h-pirrolo `2,3-cipiridin-2-ilmetil) pentan-2-ol y compuestos relacionados como ligandos glucorticoides para el tratamiento de enfermedades inflamatorias y diabetes. - Google Patents

Derivados 1,1,1-trifluoro-4-fenil-4-metil-2-(1h-pirrolo `2,3-cipiridin-2-ilmetil) pentan-2-ol y compuestos relacionados como ligandos glucorticoides para el tratamiento de enfermedades inflamatorias y diabetes.

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Publication number
MXPA06002880A
MXPA06002880A MXPA06002880A MXPA06002880A MXPA06002880A MX PA06002880 A MXPA06002880 A MX PA06002880A MX PA06002880 A MXPA06002880 A MX PA06002880A MX PA06002880 A MXPA06002880 A MX PA06002880A MX PA06002880 A MXPA06002880 A MX PA06002880A
Authority
MX
Mexico
Prior art keywords
compounds
pyrrolo
trifluoro
phenyl
methyl
Prior art date
Application number
MXPA06002880A
Other languages
English (en)
Inventor
Ji Wang
Original Assignee
Boehringer Ingelheim Pharma
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Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of MXPA06002880A publication Critical patent/MXPA06002880A/es

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Abstract

Compuestos de la Formulas (IA), (IB), (IC), y (ID) (ver formulas (IA), (IB), (IC), y (ID)) en las cuales R1, R2, R3, R4, R5 y R6 son como se definen respectivamente en la presente para las Formulas (IA), (IB), (IC), y (ID), o un tautomero, profarmaco, solvato o una sal de los mismos, composiciones farmaceuticas que contienen tales compuestos, y metodos para modular la funcion del receptor de glucocorticoides y metodos para tratar un estado o un cuadro patologico mediado por la funcion del receptor de glucocorticoides o caracterizado por procesos inflamatorios, alergicos o proliferativos en un paciente que utiliza estos compuestos.
MXPA06002880A 2003-09-24 2004-09-22 Derivados 1,1,1-trifluoro-4-fenil-4-metil-2-(1h-pirrolo `2,3-cipiridin-2-ilmetil) pentan-2-ol y compuestos relacionados como ligandos glucorticoides para el tratamiento de enfermedades inflamatorias y diabetes. MXPA06002880A (es)

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US50545603P 2003-09-24 2003-09-24
US50707903P 2003-09-29 2003-09-29
PCT/US2004/031009 WO2005030213A1 (en) 2003-09-24 2004-09-22 1,1,1-trifluoro-4-phenyl-4-methyl-2-(1h-pyrrolo

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PE20090219A1 (es) 2009-03-26
CA2539909A1 (en) 2005-04-07
RU2006113696A (ru) 2007-11-20
IL174475A0 (en) 2006-08-01
TW200526655A (en) 2005-08-16
EP1673088A1 (en) 2006-06-28
JP2007506750A (ja) 2007-03-22
US20050176706A1 (en) 2005-08-11
AU2004275757B2 (en) 2011-03-24
TWI340138B (en) 2011-04-11
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PE20090217A1 (es) 2009-03-26
AU2004275757A1 (en) 2005-04-07
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JP2010209100A (ja) 2010-09-24
BRPI0414591A (pt) 2006-11-07
KR101152690B1 (ko) 2012-07-05
JP4778430B2 (ja) 2011-09-21
RS20060201A (en) 2008-08-07
KR20060115858A (ko) 2006-11-10
CN101948425A (zh) 2011-01-19
CA2539909C (en) 2012-07-31
AR046020A1 (es) 2005-11-23
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UY28526A1 (es) 2005-04-29

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