EA200971114A1 - Определение антигенов, расположенных на эритроцитах, и антиэритроцитарных антител - Google Patents

Определение антигенов, расположенных на эритроцитах, и антиэритроцитарных антител

Info

Publication number
EA200971114A1
EA200971114A1 EA200971114A EA200971114A EA200971114A1 EA 200971114 A1 EA200971114 A1 EA 200971114A1 EA 200971114 A EA200971114 A EA 200971114A EA 200971114 A EA200971114 A EA 200971114A EA 200971114 A1 EA200971114 A1 EA 200971114A1
Authority
EA
Eurasian Patent Office
Prior art keywords
erythrocytes
antibodies
eritrotsitar
determination
antigenic molecules
Prior art date
Application number
EA200971114A
Other languages
English (en)
Other versions
EA017380B1 (ru
Inventor
Фредерик Бюффьер
Ив Рэзэн
Эльян Ривалэн
Ампаро Санхуан
Original Assignee
Био-Рад Пастеэр
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Био-Рад Пастеэр filed Critical Био-Рад Пастеэр
Publication of EA200971114A1 publication Critical patent/EA200971114A1/ru
Publication of EA017380B1 publication Critical patent/EA017380B1/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Изобретение относится к способу детекции множества антигенных молекул, расположенных на эритроцитах, и/или множества антиэритроцитарных антител, причем указанные антигенные молекулы, расположенные на эритроцитах, состоят из антигенных молекул, расположенных не только на эритроцитах, но также по меньшей мере и на одной другой клеточной популяции, отличающихся от молекул антигенов групп крови, указанный способ содержит приведение образца в контакт с различимыми бусами, на которые присоединяются (а) антитела, специфичные для указанных антигенов, или (b) эритроциты или фрагмент мембраны эритроцитов.
EA200971114A 2007-06-08 2008-06-06 Определение антигенов, расположенных на эритроцитах, и антиэритроцитарных антител EA017380B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0755624A FR2917174B1 (fr) 2007-06-08 2007-06-08 Analyse multiple d'echantillons sanguins
US92905207P 2007-06-11 2007-06-11
PCT/EP2008/057128 WO2008148890A1 (en) 2007-06-08 2008-06-06 Detection of antigens carried by erythrocytes and of anti-erythrocyte antibodies

Publications (2)

Publication Number Publication Date
EA200971114A1 true EA200971114A1 (ru) 2010-06-30
EA017380B1 EA017380B1 (ru) 2012-12-28

Family

ID=38582044

Family Applications (2)

Application Number Title Priority Date Filing Date
EA200971124A EA017186B1 (ru) 2007-06-08 2008-06-06 Множественный анализ образцов крови
EA200971114A EA017380B1 (ru) 2007-06-08 2008-06-06 Определение антигенов, расположенных на эритроцитах, и антиэритроцитарных антител

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA200971124A EA017186B1 (ru) 2007-06-08 2008-06-06 Множественный анализ образцов крови

Country Status (15)

Country Link
US (2) US8580530B2 (ru)
EP (2) EP2158492B1 (ru)
JP (2) JP5768371B2 (ru)
KR (2) KR101508699B1 (ru)
CN (2) CN101715558A (ru)
AU (2) AU2008258505B2 (ru)
BR (2) BRPI0812770A2 (ru)
CA (2) CA2687756A1 (ru)
EA (2) EA017186B1 (ru)
FR (1) FR2917174B1 (ru)
IL (2) IL202216A (ru)
MX (2) MX2009013388A (ru)
NZ (3) NZ603084A (ru)
WO (2) WO2008148886A1 (ru)
ZA (2) ZA201000095B (ru)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8169600B2 (en) * 2006-09-15 2012-05-01 Arryx, Inc. Surface mapping by optical manipulation of particles in relation to a functionalized surface
FR2917174B1 (fr) * 2007-06-08 2021-02-12 Bio Rad Pasteur Analyse multiple d'echantillons sanguins
DE102009037331A1 (de) * 2009-08-14 2011-03-03 Pluriselect Gmbh Verfahren zur Separierung von Partikeln und/oder Zellen mit 2 und mehr Oberflächenspezifitäten
FR2963107B1 (fr) * 2010-07-21 2019-06-28 Diagast Complexe immuno-magnetique et son utilisation pour le groupage/phenotypage erythrocytaire
US20120202225A1 (en) * 2011-02-01 2012-08-09 Arryx, Inc. Methods and devices for immunodiagnostic applications
US9182389B2 (en) * 2011-02-22 2015-11-10 Chrome Red Technologies, Llc Detection of specific antigens in a population of antigens
JP2014525570A (ja) * 2011-08-30 2014-09-29 ザ ガバナーズ オブ ザ ユニバーシティ オブ アルバータ Ａｂｏ抗体の検出および特性解析の方法およびシステム
US10241120B2 (en) 2011-12-06 2019-03-26 Universite Libre De Bruxelles Method and device for assaying an antigen present on erythrocytes or an antibody binding to an antigen present on erythrocytes
EP2739976B1 (en) 2011-12-21 2016-07-06 Grifols, S.A. Identification of atypical antibodies in human blood and blood products
FR2991689B1 (fr) 2012-06-11 2018-04-20 Diagast Dispositif de diagnostic immuno-hematologique et utilisations
WO2013188756A1 (en) * 2012-06-15 2013-12-19 The University Of Chicago Oligonucleotide-mediated quantitative multiplexed immunoassays
US9927439B2 (en) 2013-04-26 2018-03-27 Bio-Rad Laboratories, Inc. Multiplex hepatitis B assay
CN103344772B (zh) * 2013-07-19 2015-06-24 中国科学院苏州生物医学工程技术研究所 Miltenberger血型抗体检测新方法
CN103344755B (zh) * 2013-07-19 2015-06-24 中国科学院苏州生物医学工程技术研究所 一种磁化醛化羊红细胞的制备方法
CN104569376B (zh) * 2013-10-09 2017-11-10 常州博闻迪医药科技有限公司 一种磁微粒介导的层析检测技术装置及其用途
KR102047061B1 (ko) 2013-10-30 2019-11-20 서울대학교산학협력단 이중 표지 마이크로 디스크 및 그를 이용한 다중 검출방법
ES2765865T3 (es) * 2015-01-14 2020-06-11 Bio Rad Laboratories Sistemas y procedimientos de análisis de sangre
KR20230141834A (ko) 2015-02-09 2023-10-10 슬링샷 바이오사이언시즈 인코포레이티드 튜닝가능한 광 특성을 갖는 하이드로겔 입자 및 이를 사용하기 위한 방법
EP3165920B1 (de) 2015-11-06 2019-07-03 imusyn GmbH & Co. KG Verfahren zur analyse von serum auf anti-erythrozytäre antikörper
CN105699667B (zh) * 2016-01-26 2018-01-09 北京中科圆融生物科技发展有限公司 细菌磁颗粒红细胞膜复合颗粒及其临床应用
WO2018187348A1 (en) * 2017-04-03 2018-10-11 Immucor, Inc. Red cell diluent with edta and methods for making and using the same
CN107643409B (zh) * 2017-09-19 2021-05-04 中国人民解放军总医院 一种血型抗原芯片及其在红细胞意外抗体检测中的应用
JP2021514060A (ja) * 2018-02-16 2021-06-03 ディアガストＤｉａｇａｓｔ ビーズを含むＩｎ Ｖｉｔｒｏ診断デバイス及びその使用
CN109725144A (zh) * 2019-01-03 2019-05-07 北京蛋白质组研究中心 一种jmh血型抗原芯片及其在红细胞意外抗体检测中的应用
FR3106900A1 (fr) * 2020-02-04 2021-08-06 Innobiochips Procédé de capture et d’identification d’agglutinats cellulaires pour la détection d’anticorps anti-érythrocytaires multiplexe
CN111662869A (zh) * 2020-06-02 2020-09-15 北京康思润业生物技术有限公司 用于分离红细胞的免疫磁珠及其制备方法和应用
WO2022005953A1 (en) * 2020-06-29 2022-01-06 Siemens Healthcare Diagnostics Inc. Devices and methods for plasma separation and metering
RU2020122142A (ru) * 2020-07-03 2022-01-04 Петр Иванович Никитин Композиция и способ для улучшения эффективности и снижения побочных эффектов терапевтического агента, доставляемого к мишени с помощью магнитного поля
KR102609257B1 (ko) * 2021-11-10 2023-12-04 고대현 Abo 항체 검사 장치 및 그 검사 방법
CN114113639B (zh) * 2022-01-29 2022-04-19 北京大有天弘科技有限公司 一种血型抗体检测方法及其应用
CN114397464B (zh) * 2022-03-24 2022-06-10 天津德祥生物技术有限公司 一种红细胞膜碎片与载体的偶联复合物、其偶联方法和应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608246A (en) * 1983-03-10 1986-08-26 Immucor, Inc. Testing for a blood group immunological reaction
JPS6040958A (ja) * 1983-08-15 1985-03-04 Seitetsu Kagaku Co Ltd 血液型物質感作ゼオライト粒子
US4810632A (en) * 1986-12-01 1989-03-07 Scripps Clinic And Research Foundation Cell surface antigen detection method
JP2532670B2 (ja) * 1988-07-20 1996-09-11 オリンパス光学工業株式会社 磁性マ―カ―粒子を用いた免疫学的測定方法
JPH02165052A (ja) * 1988-12-20 1990-06-26 Olympus Optical Co Ltd 免疫学的測定方法
US6933106B2 (en) * 1995-03-13 2005-08-23 Mark Hechinger Platelet immunoglobulin bead suspension and flow cytometry
JPH0954091A (ja) * 1995-08-09 1997-02-25 Nippon Zoki Pharmaceut Co Ltd 抗赤血球抗体の測定法
US5776711A (en) * 1996-11-12 1998-07-07 The Regents Of The University Of California Simultaneous human ABO and RH(D) blood typing or antibody screening by flow cytometry
US5948627A (en) * 1997-05-30 1999-09-07 One Lambda Immunobead flow cytometric detection of anti-HLA panel-reactive antibody
AU1203199A (en) * 1997-11-18 1999-06-07 Bio-Rad Laboratories, Inc. Multiplex flow immunoassays with magnetic particles as solid phase
CA2313047A1 (en) * 1997-12-04 1999-12-16 Nicholas Thomas Multiple assay method
JP4054500B2 (ja) * 1999-12-27 2008-02-27 オリンパス株式会社 抗原、抗体及びｄｎａ等の核酸を検出用のプローブとして用いた多項目検査方法
JP4410374B2 (ja) 2000-03-31 2010-02-03 オリンパス株式会社 多項目生物試料検査方法
AU2003275940A1 (en) * 2002-10-31 2004-05-25 Chemometec A/S A method for assessment of particles
DE10330981B4 (de) * 2003-07-09 2010-04-01 Medion Diagnostics Ag Vorrichtung und Verfahren zur simultanen Durchführung von Blutgruppenbestimmung, Serumgegenprobe und Antikörpersuch-Test
TW200508609A (en) * 2003-07-15 2005-03-01 Bioarray Solutions Ltd Detection of cell membrane-associated proteins using membrane fragments displayed on encoded microparticle arrays
GB0506183D0 (en) * 2005-03-24 2005-05-04 Univ Edinburgh Antigen detection
FR2917174B1 (fr) * 2007-06-08 2021-02-12 Bio Rad Pasteur Analyse multiple d'echantillons sanguins

Also Published As

Publication number Publication date
EP2160609A1 (en) 2010-03-10
JP5768371B2 (ja) 2015-08-26
AU2008258509A1 (en) 2008-12-11
US20100184101A1 (en) 2010-07-22
JP2010529445A (ja) 2010-08-26
KR20100046138A (ko) 2010-05-06
WO2008148886A1 (en) 2008-12-11
ZA201000095B (en) 2010-09-29
NZ581716A (en) 2012-11-30
EP2158492A1 (en) 2010-03-03
IL202216A (en) 2015-11-30
FR2917174A1 (fr) 2008-12-12
US20100178656A1 (en) 2010-07-15
WO2008148890A1 (en) 2008-12-11
NZ603084A (en) 2014-08-29
ZA201000093B (en) 2011-04-28
CA2687756A1 (en) 2008-12-11
EA200971124A1 (ru) 2010-06-30
AU2008258509B2 (en) 2014-01-16
JP5587179B2 (ja) 2014-09-10
CN101711363A (zh) 2010-05-19
JP2010529444A (ja) 2010-08-26
US8580531B2 (en) 2013-11-12
BRPI0812770A2 (pt) 2014-12-02
MX2009013411A (es) 2010-04-09
US8580530B2 (en) 2013-11-12
EA017186B1 (ru) 2012-10-30
KR101524107B1 (ko) 2015-05-29
AU2008258505B2 (en) 2014-08-28
CA2687829A1 (en) 2008-12-11
AU2008258505A1 (en) 2008-12-11
IL202322A0 (en) 2010-06-30
IL202216A0 (en) 2010-06-16
EP2160609B1 (en) 2018-11-28
EA017380B1 (ru) 2012-12-28
NZ581717A (en) 2012-03-30
KR20100043180A (ko) 2010-04-28
CN101715558A (zh) 2010-05-26
KR101508699B1 (ko) 2015-04-08
MX2009013388A (es) 2010-04-09
BRPI0812772A2 (pt) 2014-12-02
FR2917174B1 (fr) 2021-02-12
EP2158492B1 (en) 2018-11-28

Similar Documents

Publication Publication Date Title
EA200971114A1 (ru) Определение антигенов, расположенных на эритроцитах, и антиэритроцитарных антител
MX2007014815A (es) Metodos de inmunoanalisis mejorados.
NZ609363A (en) Methods for determining anti-drug antibody isotypes
ATE528648T1 (de) Verfahren zum nachweis antikörper-herstellender zellen
JP2016507723A5 (ru)
NO20076662L (no) Deteksjon av et malantigen uavhengig av tilstedevaerelse eller fravaer av et korresponderende terapeutisk antistoff
WO2010002911A3 (en) Methods and materials for monitoring myeloma using quantitative mass spetrometry
IN2012DN06139A (ru)
EA200971123A1 (ru) Мультиплексный способ выявления инфекции
RU2012148244A (ru) Способ диагностики онкологических заболеваний и иммуноферментный набор для его осуществления
FR2935384B1 (fr) Procede de detection du virus de la rougeole, dispositif et kit utilisant ce procede
RU2018103933A (ru) Моноклональные антитела, с ориентировкой на антиген Р респираторно-синцитиального вируса человека, получаемые и секретируемые из клеточных гибридом, используемые для обнаружения и диагностики инфекции, вызываемой респираторно-синцитиальным вирусом
ATE489632T1 (de) Antigennachweis
WO2007008092A3 (en) Diagnostic kit for the examination of animal sera for the presence of anti-rhd antibodies and a diagnostic kit for detecting the rhd virus
NO20062280L (no) Test
WO2018172337A8 (en) IMMUNOASSAY FOR THE DETECTION OF ZIKA VIRUS INFECTION
EP4253950A3 (en) Ce-western applications for antibody development
WO2016135246A3 (en) Antibody detection method and system
CY1109461T1 (el) Βελτιωμενες μεθοδοι ανοσολογικου προσδιορισμου
TW200722527A (en) Methods of detecting hepatitis C virus
CN111257566B (zh) 用于检测同种异体的、或供者特异性的非hla抗体的方法
MX2021014171A (es) Metodos para identificar y cuantificar proteinas de la celula huesped.
TW201144810A (en) Kits for RhD blood type determination and method for RhD blood type determination by using the same
JP2012522222A5 (ru)
RU2017120228A (ru) Особые моноклональные антитела антигена м метапневмовируса человека (hmpv) и способ их использования в методе диагностики

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU