WO2007008092A3 - Diagnostic kit for the examination of animal sera for the presence of anti-rhd antibodies and a diagnostic kit for detecting the rhd virus - Google Patents

Diagnostic kit for the examination of animal sera for the presence of anti-rhd antibodies and a diagnostic kit for detecting the rhd virus Download PDF

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Publication number
WO2007008092A3
WO2007008092A3 PCT/PL2006/000046 PL2006000046W WO2007008092A3 WO 2007008092 A3 WO2007008092 A3 WO 2007008092A3 PL 2006000046 W PL2006000046 W PL 2006000046W WO 2007008092 A3 WO2007008092 A3 WO 2007008092A3
Authority
WO
WIPO (PCT)
Prior art keywords
diagnostic kit
rhd
virus
examination
detecting
Prior art date
Application number
PCT/PL2006/000046
Other languages
French (fr)
Other versions
WO2007008092A2 (en
Inventor
Andrzej Fitzner
Andrzej Kesy
Boguslaw Szewczyk
Beata Gromadzka
Original Assignee
Panstwowy Inst Weterynaryjny P
Univ Gdanski
Andrzej Fitzner
Andrzej Kesy
Boguslaw Szewczyk
Beata Gromadzka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panstwowy Inst Weterynaryjny P, Univ Gdanski, Andrzej Fitzner, Andrzej Kesy, Boguslaw Szewczyk, Beata Gromadzka filed Critical Panstwowy Inst Weterynaryjny P
Priority to EP06769510A priority Critical patent/EP1904850A2/en
Publication of WO2007008092A2 publication Critical patent/WO2007008092A2/en
Publication of WO2007008092A3 publication Critical patent/WO2007008092A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/16011—Caliciviridae
    • C12N2770/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Abstract

The subjects of the present invention are a diagnostic kit for the examination of animal sera for the presence of anti-RHD antibodies and a diagnostic kit for detecting the RHDD virus. The subjects of the present invention facilitate the application in ELISA tests of specific (monospecific) anti-sera obtained as a result of the immunization of laboratory animals with purified, recombinant RHD virus antigens (VLP RHDV). This yields high specificity, sensitivity and repeatability of the results obtained. The application of a control system composed of a positive antigen, a negative virus control as well as control sera in the test makes it possible to quickly and accurately determine studied samples as positive or negative.
PCT/PL2006/000046 2005-07-08 2006-07-06 Diagnostic kit for the examination of animal sera for the presence of anti-rhd antibodies and a diagnostic kit for detecting the rhd virus WO2007008092A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06769510A EP1904850A2 (en) 2005-07-08 2006-07-06 Diagnostic kit for the examination of animal sera for the presence of anti-rhd antibodies and a diagnostic kit for detecting the rhd virus

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PLP-376121 2005-07-08
PL376121A PL205228B1 (en) 2005-07-08 2005-07-08 Diagnostic set for the examination of animal serum for presence of RHD antibodies and diagnostic set for detection of the RHD virus

Publications (2)

Publication Number Publication Date
WO2007008092A2 WO2007008092A2 (en) 2007-01-18
WO2007008092A3 true WO2007008092A3 (en) 2008-05-08

Family

ID=37401477

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/PL2006/000046 WO2007008092A2 (en) 2005-07-08 2006-07-06 Diagnostic kit for the examination of animal sera for the presence of anti-rhd antibodies and a diagnostic kit for detecting the rhd virus

Country Status (3)

Country Link
EP (1) EP1904850A2 (en)
PL (1) PL205228B1 (en)
WO (1) WO2007008092A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102250234B (en) * 2011-06-13 2013-04-17 中国农业科学院哈尔滨兽医研究所 Protein bonded with rabbit hemorrhagic disease virus VP60 protein and application thereof
CN105486861B (en) * 2015-07-02 2017-07-11 山东省滨州畜牧兽医研究院 A kind of Rabbit pest virus antibody rapid detection card and preparation method thereof
CN105277696A (en) * 2015-10-26 2016-01-27 中国农业科学院上海兽医研究所 Double-antibody sandwich ELISA (enzyme-linked immuno sorbent assay) detection kit for RHDV (rabbit hemorrhagic disease virus) and application method
CN106802349A (en) * 2016-12-30 2017-06-06 广东华南联合疫苗开发院有限公司 Sf insect cell host cell proteins Double-antibody sandwich enzymelinked immunosorbent detection kits and method
CN109856397B (en) * 2018-12-26 2022-06-21 山东绿都生物科技有限公司 Colloidal gold detection card for rapidly detecting rabbit plague virus and preparation method thereof
CN113252891A (en) * 2021-01-08 2021-08-13 中国农业科学院兰州兽医研究所 Kit for detecting Seneca virus A antibody
CN112881710B (en) * 2021-02-04 2022-04-22 中国农业科学院兰州兽医研究所 Inhibition ELISA method for detecting foot-and-mouth disease virus antibody and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0704528A2 (en) * 1994-07-08 1996-04-03 Cyanamid Iberica, Sa Rabbit hemorrhagic disease virus (RHDV) recombinant capsids and proteins, diagnostic kits and vaccines containing them

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0704528A2 (en) * 1994-07-08 1996-04-03 Cyanamid Iberica, Sa Rabbit hemorrhagic disease virus (RHDV) recombinant capsids and proteins, diagnostic kits and vaccines containing them

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
COLLINS, B.J., ET AL: "Presence of rabbit haemorrhagic disease virus antigen in rabbit tissue as revealed by a monoclonal antibody dependent capture ELISA", JOURNAL OF VIROLOGICAL METHODS, vol. 58, 1996, pages 145 - 154, XP002408956 *
FARNOS, O., ET AL: "High-level expression and immunogenic properties of the recombinant rabbit hemorrhagic disease virus VP60 capsid protein obtained in Pichia pastoris", JOURNAL OF BIOTECHNOLOGY, vol. 117, 25 May 2005 (2005-05-25), pages 215 - 224, XP004872684 *
GROMADZKA, B., ET AL: "Recombinant VP60 in the form of virion-like particles as a potential vaccine against rabbit hemorrhagic disease virus", ACTA BIOCHIMICA POLONICA, vol. 53, no. 2, 30 May 2006 (2006-05-30), pages 371 - 376, XP002408957 *
LAURENT S ET AL: "RECOMBINANT RABBIT HEMORRHAGIC DISEASE VIRUS CAPSID PROTEIN EXPRESSED IN BACULOVIRUS SELF-ASSEMBLES INTO VIRUSLIKE PARTICLES AND INDUCES PROTECTION", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 68, no. 10, 1 October 1994 (1994-10-01), pages 6794 - 6798, XP002002209, ISSN: 0022-538X *
MARTINEZ-TORRECUADRADA, J. L., ET AL: "Antigenic structure of the capsid protein of rabbit haemorrhagic disease virus", JOURNAL OF GENERAL VIROLOGY, vol. 79, 1998, pages 1901 - 1909, XP002408955 *
NAGESHA, H.S., ET AL: "Self-assembly, antigenicity, and immunogenicity of the rabbit haemorrhagic disease virus (Czechoslovakian strain V-351) capsid protein expressed in baculovirus", ARCHIVES OF VIROLOGY, vol. 140, 1995, pages 1095 - 1108, XP009075295 *
NARDELLI, S., ET AL: "Diagnosis of Rabbit Haemorrhagic Disease (RHD) and European Brown HAre Syndrome (EBHS) by Indirect sandwich Polyclonal ELISA", JOURNAL OF VETERINARY MEDICINE, SERIES B, vol. 43, 1996, pages 393 - 400, XP009075239 *
See also references of EP1904850A2 *

Also Published As

Publication number Publication date
PL205228B1 (en) 2010-03-31
EP1904850A2 (en) 2008-04-02
WO2007008092A2 (en) 2007-01-18
PL376121A1 (en) 2007-01-22

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