EA200500536A1 - Антагонисты рецептора pgd2 для лечения воспалительных заболеваний - Google Patents

Антагонисты рецептора pgd2 для лечения воспалительных заболеваний

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Publication number
EA200500536A1
EA200500536A1 EA200500536A EA200500536A EA200500536A1 EA 200500536 A1 EA200500536 A1 EA 200500536A1 EA 200500536 A EA200500536 A EA 200500536A EA 200500536 A EA200500536 A EA 200500536A EA 200500536 A1 EA200500536 A1 EA 200500536A1
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Eurasian Patent Office
Prior art keywords
treatment
receptor antagonists
inflammatory diseases
pgd2 receptor
receptor
Prior art date
Application number
EA200500536A
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English (en)
Other versions
EA011385B1 (ru
Inventor
Шомир Гош
Эйми М. Элдер
Кеннет Дж. Карсон
Кевин Спротт
Шон Харрисон
Original Assignee
Миллениум Фармасьютикалз, Инк.
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Application filed by Миллениум Фармасьютикалз, Инк. filed Critical Миллениум Фармасьютикалз, Инк.
Publication of EA200500536A1 publication Critical patent/EA200500536A1/ru
Publication of EA011385B1 publication Critical patent/EA011385B1/ru

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  • Neurosurgery (AREA)

Abstract

В изобретении описаны соединения, представленные структурной формулой (I)где все переменные определены в описании. Кроме того, описано применение таких соединений для ингибирования спаренного с G-протеином рецептора, названного как хемоатрактантный рецептор-гомологичная молекула, выраженная на Th2 ("CRTH2") для лечения воспалительных нарушений.Отчет о международном поиске был опубликован 2004.07.15.
EA200500536A 2002-10-04 2003-10-03 Антагонисты рецептора pgd2 для лечения воспалительных заболеваний EA011385B1 (ru)

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BR0315041A (pt) 2005-08-16
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US7211672B2 (en) 2007-05-01
MXPA05003456A (es) 2005-07-05
NO20051566L (no) 2005-06-15
AU2003277285B2 (en) 2007-12-13
US20040082609A1 (en) 2004-04-29
WO2004032848A2 (en) 2004-04-22
ZA200502692B (en) 2006-11-29
PL376156A1 (en) 2005-12-27
JP2006508077A (ja) 2006-03-09
KR20050055747A (ko) 2005-06-13
AU2003277285A1 (en) 2004-05-04
JP2006124396A (ja) 2006-05-18
EA011385B1 (ru) 2009-02-27
CN1720047A (zh) 2006-01-11
EP1556047A2 (en) 2005-07-27
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