MX2007003335A - Acidos aceticos de bencimidazol que muestran antagonismo de receptor crth2 y usos de los mismos. - Google Patents

Acidos aceticos de bencimidazol que muestran antagonismo de receptor crth2 y usos de los mismos.

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Publication number
MX2007003335A
MX2007003335A MX2007003335A MX2007003335A MX2007003335A MX 2007003335 A MX2007003335 A MX 2007003335A MX 2007003335 A MX2007003335 A MX 2007003335A MX 2007003335 A MX2007003335 A MX 2007003335A MX 2007003335 A MX2007003335 A MX 2007003335A
Authority
MX
Mexico
Prior art keywords
acetic acids
receptor antagonism
crth2 receptor
crth2
acids exhibiting
Prior art date
Application number
MX2007003335A
Other languages
English (en)
Inventor
Youssef L Bennani
L Nathan Tumey
Elizabeth Ann Gleason
Michael Joseph Robarge
Original Assignee
Athersys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Athersys Inc filed Critical Athersys Inc
Publication of MX2007003335A publication Critical patent/MX2007003335A/es

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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
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Abstract

La invencion se refiere a compuestos de acido acetico de bencimidazol los cuales funcionan como antagonistas de la molecula receptora-homologa quimioatrayente expresada en el receptor de celulas tipo 2 T-Auxiliar (CRTH2). La invencion tambien se refiere al uso de estos compuestos para inhibir la union de prostaglandina D2 y sus metabolitos o ciertos metabolitos de tromboxano al receptor CRTH2 y para tratar los desordenes responsivos a tal inhibicion.
MX2007003335A 2004-09-21 2005-09-21 Acidos aceticos de bencimidazol que muestran antagonismo de receptor crth2 y usos de los mismos. MX2007003335A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61129604P 2004-09-21 2004-09-21
PCT/US2005/034028 WO2006034418A2 (en) 2004-09-21 2005-09-21 Benzimidazole acetic acids exhibiting crth2 receptor antagonism and uses thereof

Publications (1)

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MX2007003335A true MX2007003335A (es) 2007-06-05

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MX2007003335A MX2007003335A (es) 2004-09-21 2005-09-21 Acidos aceticos de bencimidazol que muestran antagonismo de receptor crth2 y usos de los mismos.

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US (2) US7732618B2 (es)
EP (1) EP1814865A4 (es)
JP (1) JP2008513511A (es)
KR (1) KR20070115865A (es)
CN (1) CN101124207A (es)
AU (1) AU2005286717A1 (es)
BR (1) BRPI0515522A (es)
CA (1) CA2581335A1 (es)
EA (1) EA200700711A1 (es)
IL (1) IL182103A0 (es)
MX (1) MX2007003335A (es)
WO (1) WO2006034418A2 (es)

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