EA200201140A1 - Устройство для доставки лекарств с пролонгированным высвобождением, способы применения и способы их изготовления - Google Patents

Устройство для доставки лекарств с пролонгированным высвобождением, способы применения и способы их изготовления

Info

Publication number
EA200201140A1
EA200201140A1 EA200201140A EA200201140A EA200201140A1 EA 200201140 A1 EA200201140 A1 EA 200201140A1 EA 200201140 A EA200201140 A EA 200201140A EA 200201140 A EA200201140 A EA 200201140A EA 200201140 A1 EA200201140 A1 EA 200201140A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
delivery
effective agent
drugs
production
Prior art date
Application number
EA200201140A
Other languages
English (en)
Other versions
EA004980B1 (ru
Inventor
Хонг Гуо
Пол Эштон
Original Assignee
Контрол Деливери Системз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Контрол Деливери Системз, Инк. filed Critical Контрол Деливери Системз, Инк.
Publication of EA200201140A1 publication Critical patent/EA200201140A1/ru
Publication of EA004980B1 publication Critical patent/EA004980B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining
    • Y10T29/49888—Subsequently coating

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Предложены способ и устройство для лечения организма млекопитающего для получения желаемого местного или системного физиологического или фармакологического эффекта. Способ включает в себя введение устройства доставки лекарства с пролонгированным высвобождением в организм млекопитающего, нуждающегося в таком лечении, в область, в которой желательно высвобождение эффективного агента, и предоставление возможности эффективному агенту выходить из устройства регулируемым образом. Устройство включает в себя внутреннее ядро или резервуар, содержащий эффективный агент, непроницаемую трубку, которая закрывает части резервуара, и проницаемый элемент на конце трубки.Отчет о международном поиске был опубликован 2002.06.20.
EA200201140A 2000-04-26 2001-04-19 Устройства для доставки лекарств с пролонгированным высвобождением, способы применения и способы их изготовления EA004980B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/558,207 US6375972B1 (en) 2000-04-26 2000-04-26 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
PCT/US2001/012700 WO2001080825A2 (en) 2000-04-26 2001-04-19 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof

Publications (2)

Publication Number Publication Date
EA200201140A1 true EA200201140A1 (ru) 2003-02-27
EA004980B1 EA004980B1 (ru) 2004-10-28

Family

ID=24228594

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200201140A EA004980B1 (ru) 2000-04-26 2001-04-19 Устройства для доставки лекарств с пролонгированным высвобождением, способы применения и способы их изготовления

Country Status (24)

Country Link
US (7) US6375972B1 (ru)
EP (2) EP1276462B1 (ru)
JP (1) JP4705304B2 (ru)
KR (1) KR100854541B1 (ru)
CN (4) CN101396335A (ru)
AR (1) AR028372A1 (ru)
AT (1) ATE409023T1 (ru)
AU (4) AU5367501A (ru)
BR (1) BR0110243A (ru)
CA (1) CA2406277C (ru)
CY (1) CY1108665T1 (ru)
DE (1) DE60135907D1 (ru)
DK (1) DK1276462T3 (ru)
EA (1) EA004980B1 (ru)
ES (1) ES2315282T3 (ru)
HK (1) HK1053263B (ru)
IL (2) IL152294A0 (ru)
MX (1) MXPA02010442A (ru)
NZ (2) NZ522002A (ru)
PT (1) PT1276462E (ru)
SI (1) SI1276462T1 (ru)
TW (1) TWI290054B (ru)
WO (1) WO2001080825A2 (ru)
ZA (1) ZA200208415B (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2539556C2 (ru) * 2009-08-31 2015-01-20 Джонсон Энд Джонсон Вижн Кэа, Инк. Пульсирующая подача лекарственных средств из пробки для слезной точки

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CY1108665T1 (el) 2014-04-09
CA2406277C (en) 2013-06-11
EA004980B1 (ru) 2004-10-28
US8574659B2 (en) 2013-11-05
KR100854541B1 (ko) 2008-08-26
ES2315282T3 (es) 2009-04-01
US20100119580A1 (en) 2010-05-13
DK1276462T3 (da) 2009-02-09
NZ522002A (en) 2004-06-25
HK1053263A1 (en) 2003-10-17
WO2001080825A3 (en) 2002-06-20
DE60135907D1 (de) 2008-11-06
ATE409023T1 (de) 2008-10-15
KR20030009447A (ko) 2003-01-29
IL152294A (en) 2013-04-30
TWI290054B (en) 2007-11-21
AU2006202338A1 (en) 2006-06-22
CN1438873A (zh) 2003-08-27
JP2003530964A (ja) 2003-10-21
US6375972B1 (en) 2002-04-23
ZA200208415B (en) 2003-10-17
US20020102307A1 (en) 2002-08-01
AU2006202338B2 (en) 2008-09-18
EP1982701A3 (en) 2009-07-15
IL152294A0 (en) 2003-05-29

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