EA200100354A1 - Фармацевтическая композиция, содержащая энтакапон или нитекапон, а также поперечно-сшитое производное целлюлозы - Google Patents

Фармацевтическая композиция, содержащая энтакапон или нитекапон, а также поперечно-сшитое производное целлюлозы

Info

Publication number
EA200100354A1
EA200100354A1 EA200100354A EA200100354A EA200100354A1 EA 200100354 A1 EA200100354 A1 EA 200100354A1 EA 200100354 A EA200100354 A EA 200100354A EA 200100354 A EA200100354 A EA 200100354A EA 200100354 A1 EA200100354 A1 EA 200100354A1
Authority
EA
Eurasian Patent Office
Prior art keywords
nitekapon
entacapon
transformed
cellulose
pharmaceutical composition
Prior art date
Application number
EA200100354A
Other languages
English (en)
Other versions
EA003282B1 (ru
Inventor
Кари Вахервуо
Original Assignee
Орион Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22542186&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200100354(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Орион Корпорейшн filed Critical Орион Корпорейшн
Publication of EA200100354A1 publication Critical patent/EA200100354A1/ru
Publication of EA003282B1 publication Critical patent/EA003282B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Настоящее изобретение относится к пероральной прессованной композиции, содержащей энтакапон, нитекапон или их фармацевтически приемлемую соль и поперечно-сшитое производное целлюлозы. Композиция основана на том, что поперечно-сшитое производное целлюлозы увеличивает скорость высвобождения энтакапона или нитекапона из пероральной прессованной композиции. Предпочтительным количеством поперечно-сшитого производного целлюлозы в композиции является, по крайней мере, 6% по весу, предпочтительно приблизительно от 8 до 16% по весу, особенно от 10 до 14% по весу.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200100354A 1998-09-14 1999-09-13 Фармацевтическая композиция, содержащая энтакапон или нитекапон, а также поперечно-сшитое производное целлюлозы EA003282B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/152,263 US6599530B2 (en) 1998-09-14 1998-09-14 Oral compacted composition comprising catechol derivatives
PCT/FI1999/000740 WO2000015196A1 (en) 1998-09-14 1999-09-13 Pharmaceutical composition comprising entacapone or nitecapone as well as a cross-linked cellulose derivative

Publications (2)

Publication Number Publication Date
EA200100354A1 true EA200100354A1 (ru) 2001-08-27
EA003282B1 EA003282B1 (ru) 2003-04-24

Family

ID=22542186

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200100354A EA003282B1 (ru) 1998-09-14 1999-09-13 Фармацевтическая композиция, содержащая энтакапон или нитекапон, а также поперечно-сшитое производное целлюлозы

Country Status (39)

Country Link
US (1) US6599530B2 (ru)
EP (1) EP1112065B1 (ru)
JP (1) JP4619537B2 (ru)
KR (1) KR100732187B1 (ru)
CN (1) CN1151778C (ru)
AR (1) AR021806A1 (ru)
AT (1) ATE256454T1 (ru)
AU (1) AU746889B2 (ru)
BG (1) BG65041B1 (ru)
BR (1) BR9913681A (ru)
CA (1) CA2342634C (ru)
CO (1) CO5130008A1 (ru)
CZ (1) CZ293960B6 (ru)
DE (1) DE69913714T2 (ru)
DK (1) DK1112065T3 (ru)
EA (1) EA003282B1 (ru)
EE (1) EE04657B1 (ru)
ES (1) ES2213381T3 (ru)
GE (1) GEP20033062B (ru)
HK (1) HK1039750B (ru)
HR (1) HRP20010277B1 (ru)
HU (1) HU228910B1 (ru)
ID (1) ID29026A (ru)
IL (1) IL141681A0 (ru)
ME (1) ME00706B (ru)
MY (1) MY124394A (ru)
NO (1) NO331641B1 (ru)
NZ (1) NZ510583A (ru)
PE (1) PE20001060A1 (ru)
PL (1) PL193454B1 (ru)
PT (1) PT1112065E (ru)
RS (1) RS49723B (ru)
SI (1) SI1112065T1 (ru)
SK (1) SK284049B6 (ru)
TR (1) TR200100752T2 (ru)
TW (1) TWI222367B (ru)
UA (1) UA73925C2 (ru)
WO (1) WO2000015196A1 (ru)
ZA (1) ZA200102084B (ru)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI109453B (fi) 1999-06-30 2002-08-15 Orion Yhtymae Oyj Farmaseuttinen koostumus
FI20000635A0 (fi) * 2000-03-17 2000-03-17 Orion Yhtymae Oyj COMT-inhibiittoreiden käyttö analgeettina
US7659253B2 (en) * 2002-02-22 2010-02-09 Shire Llc Abuse-resistant amphetamine prodrugs
US20060173074A1 (en) 2004-11-10 2006-08-03 Juha Ellmen Treatment of restless legs syndrome
EA013161B1 (ru) * 2005-06-08 2010-02-26 Орион Корпорейшн Дозированная форма для перорального применения
AU2012216377C1 (en) * 2005-06-08 2013-10-10 Orion Corporation Oral dosage form
WO2007069274A2 (en) * 2005-11-09 2007-06-21 Torrent Pharmaceuticals Limited Pharmaceutical composition comprising a compound having a catechol moiety and an alkalising agent
CA2642761A1 (en) * 2006-02-23 2007-08-30 Iomedix Sleep International Srl Compositions and methods for the induction and maintenance of quality sleep
GB2429645A (en) * 2006-03-10 2007-03-07 Sekhsaria Chemicals Ltd Solid pharmaceutical composition comprising a COMT inhibitor, a starch and a wetting agent
WO2007113371A1 (en) * 2006-03-31 2007-10-11 Iprbox Oy Pharmaceutical composition and preparation method thereof
CA2572004A1 (en) * 2006-12-08 2008-06-08 Bernard Charles Sherman Tablets comprising entacapone and crospovidone
EP1946756A1 (en) * 2007-01-17 2008-07-23 Revotar Biopharmaceuticals AG Use of entacapone in cosmetic, dermatological and pharmaceutical compositions
EP2252284B1 (en) * 2008-02-06 2011-05-25 Wockhardt Research Centre Pharmaceutical compositions of entacapone, levodopa and carbidopa with improved bioavailability
EP2293791B1 (en) * 2008-02-06 2011-11-23 Wockhardt Limited Pharmaceutical compositions of entacapone co-micronized with sugar alcohols
RU2540465C2 (ru) * 2008-08-22 2015-02-10 Вокхардт Рисерч Сентер Фармацевтическая композиция энтакапона или его солей пролонгрированного высвобождения
US9750702B2 (en) * 2009-12-25 2017-09-05 Innopharmax, Inc. Pharmaceutical composition for treating parkinson's disease and preparation method thereof
WO2012147099A1 (en) 2011-04-25 2012-11-01 Suven Nishtaa Pharma Pvt. Ltd. Pharmaceutical compositions of levodopa, carbidopa and entacapone
EA025627B1 (ru) * 2011-04-26 2017-01-30 Иннофармакс, Инк. Композиция для лечения болезни паркинсона
JP2018500300A (ja) 2014-11-28 2018-01-11 ノヴィファーマ，エス．アー． パーキンソン病を遅延させるための医薬
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
EP3275433A1 (en) * 2016-07-29 2018-01-31 Som Innovation Biotech S.L. Sustained release composition comprising micronized tolcapone
CN106236720A (zh) * 2016-08-29 2016-12-21 海南通用康力制药有限公司 一种恩他卡朋的药物组合物及其制备方法
CN113274362A (zh) * 2021-03-31 2021-08-20 海南通用康力制药有限公司 恩他卡朋片的生产方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987005804A1 (en) * 1986-04-01 1987-10-08 The Upjohn Company Methylprednisolone/sodium carboxymethyl starch tablet composition
YU213587A (en) * 1986-11-28 1989-06-30 Orion Yhtymae Oy Process for obtaining new pharmacologic active cateholic derivatives
US5283352A (en) * 1986-11-28 1994-02-01 Orion-Yhtyma Oy Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
US5489614A (en) * 1987-11-27 1996-02-06 Orion-Yhtyma Oy Catechol derivatives, their physiologically acceptable salts, esters and use
US5380535A (en) * 1991-05-28 1995-01-10 Geyer; Robert P. Chewable drug-delivery compositions and methods for preparing the same
TW430561B (en) * 1995-12-20 2001-04-21 Gea Farmaceutisk Fabrik As Rapid release tablet composition comprising tolfenamic acid or a pharmaceutically acceptable salt thereof as active ingredient and a method of preparing such tablet

Also Published As

Publication number Publication date
YU19301A (sh) 2003-02-28
ID29026A (id) 2001-07-26
CZ293960B6 (cs) 2004-08-18
AU5748299A (en) 2000-04-03
BG105436A (en) 2001-11-30
TR200100752T2 (tr) 2001-10-22
BR9913681A (pt) 2001-06-05
UA73925C2 (ru) 2005-10-17
RS49723B (sr) 2007-12-31
AR021806A1 (es) 2002-08-07
SK3072001A3 (en) 2002-05-09
SK284049B6 (sk) 2004-08-03
HRP20010277A2 (en) 2002-06-30
CA2342634A1 (en) 2000-03-23
HRP20010277B1 (en) 2010-10-31
DE69913714T2 (de) 2004-10-07
JP2002524493A (ja) 2002-08-06
CA2342634C (en) 2008-01-29
CN1319005A (zh) 2001-10-24
IL141681A0 (en) 2002-03-10
EE200100147A (et) 2002-06-17
BG65041B1 (bg) 2007-01-31
US20020132009A1 (en) 2002-09-19
HUP0103454A2 (hu) 2002-01-28
PE20001060A1 (es) 2000-10-20
AU746889B2 (en) 2002-05-02
CZ2001792A3 (cs) 2001-08-15
HU228910B1 (en) 2013-06-28
JP4619537B2 (ja) 2011-01-26
ME00706B (me) 2007-12-31
EP1112065A1 (en) 2001-07-04
EE04657B1 (et) 2006-08-15
EA003282B1 (ru) 2003-04-24
NO20011278L (no) 2001-03-13
PT1112065E (pt) 2004-04-30
SI1112065T1 (en) 2004-04-30
WO2000015196A1 (en) 2000-03-23
CN1151778C (zh) 2004-06-02
EP1112065B1 (en) 2003-12-17
ATE256454T1 (de) 2004-01-15
KR20010075084A (ko) 2001-08-09
HK1039750B (zh) 2005-02-18
TWI222367B (en) 2004-10-21
DE69913714D1 (de) 2004-01-29
DK1112065T3 (da) 2004-04-05
NO20011278D0 (no) 2001-03-13
US6599530B2 (en) 2003-07-29
CO5130008A1 (es) 2002-02-27
PL193454B1 (pl) 2007-02-28
NZ510583A (en) 2002-09-27
GEP20033062B (en) 2003-09-25
HUP0103454A3 (en) 2003-11-28
NO331641B1 (no) 2012-02-13
PL346618A1 (en) 2002-02-25
HK1039750A1 (en) 2002-05-10
ES2213381T3 (es) 2004-08-16
KR100732187B1 (ko) 2007-06-27
MY124394A (en) 2006-06-30
ZA200102084B (en) 2002-06-13

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MK4A Patent expired

Designated state(s): RU