EA200000245A1 - Быстро дезинтегрирующие таблетки метилцеллюлозы - Google Patents

Быстро дезинтегрирующие таблетки метилцеллюлозы

Info

Publication number
EA200000245A1
EA200000245A1 EA200000245A EA200000245A EA200000245A1 EA 200000245 A1 EA200000245 A1 EA 200000245A1 EA 200000245 A EA200000245 A EA 200000245A EA 200000245 A EA200000245 A EA 200000245A EA 200000245 A1 EA200000245 A1 EA 200000245A1
Authority
EA
Eurasian Patent Office
Prior art keywords
quickly disintegrating
metal cellulose
cellulose tablets
tablets
disintegrating metal
Prior art date
Application number
EA200000245A
Other languages
English (en)
Other versions
EA003663B1 (ru
Inventor
Брюс Дэджи
Нареш И. Мета
Прийасхри Найак
Original Assignee
Смитклайн Бичам Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Смитклайн Бичам Корпорейшн filed Critical Смитклайн Бичам Корпорейшн
Publication of EA200000245A1 publication Critical patent/EA200000245A1/ru
Publication of EA003663B1 publication Critical patent/EA003663B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Данное изобретение относится к новой фармацевтической композиции и к способу получения таблеток метилцеллюлозы для перорального введения, которые быстро дезинтегрируют и удовлетворяют стандартам Фармакопеи США в 0,1 N соляной кислоте и в воде.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200000245A 1997-08-22 1998-08-21 Быстро дезинтегрирующие таблетки на основе метилцеллюлозы EA003663B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5689997P 1997-08-22 1997-08-22
US8164498P 1998-04-14 1998-04-14
PCT/US1998/017440 WO1999009959A1 (en) 1997-08-22 1998-08-21 Rapidly disintegrating methylcellulose tablets

Publications (2)

Publication Number Publication Date
EA200000245A1 true EA200000245A1 (ru) 2000-08-28
EA003663B1 EA003663B1 (ru) 2003-08-28

Family

ID=26735830

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200000245A EA003663B1 (ru) 1997-08-22 1998-08-21 Быстро дезинтегрирующие таблетки на основе метилцеллюлозы

Country Status (18)

Country Link
US (2) US6372253B1 (ru)
EP (1) EP1014949A4 (ru)
JP (1) JP2001513546A (ru)
KR (1) KR20010023198A (ru)
CN (1) CN1240374C (ru)
AR (3) AR016827A1 (ru)
AU (1) AU745682B2 (ru)
BR (1) BR9811987A (ru)
CA (1) CA2301132C (ru)
CO (1) CO4960646A1 (ru)
EA (1) EA003663B1 (ru)
HU (1) HUP0003186A3 (ru)
MY (1) MY137768A (ru)
NZ (1) NZ502890A (ru)
PL (1) PL338786A1 (ru)
TW (1) TWI228421B (ru)
UA (1) UA70926C2 (ru)
WO (1) WO1999009959A1 (ru)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) * 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
AR016827A1 (es) * 1997-08-22 2001-08-01 Smithkline Beecham Corp PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
AR017512A1 (es) * 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
US6348264B1 (en) 1998-04-27 2002-02-19 Roquette Freres Process for producing low de starch hydrolysates by nanofiltration fractionation, products obtained thereby, and use of such products
JP2002524410A (ja) * 1998-09-08 2002-08-06 スミスクライン・ビーチャム・コーポレイション リプスタチン誘導体−可溶性繊維錠剤
ES2197064T3 (es) * 2000-10-24 2004-01-01 Fit Gmbh Granulado de agentes de desintegracion conjuntamente elaborados.
TWI337083B (en) * 2001-01-26 2011-02-11 Schering Corp Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
CN100339078C (zh) 2002-12-16 2007-09-26 橘生药品工业株式会社 固体口服剂型药物
US8367111B2 (en) * 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
WO2005009395A2 (en) * 2003-07-23 2005-02-03 L. Perrigo Company Cellulosic fiber containing composition
US7198653B2 (en) 2003-07-31 2007-04-03 Delavau Llc Calcium carbonate granulation
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
JP4740740B2 (ja) * 2003-12-09 2011-08-03 大日本住友製薬株式会社 薬物含有粒子および該粒子を含む固形製剤
US8747895B2 (en) * 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
EP2417969A1 (en) 2004-10-21 2012-02-15 Aptalis Pharmatech, Inc. Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US7344907B2 (en) * 2004-11-19 2008-03-18 International Business Machines Corporation Apparatus and methods for encapsulating microelectromechanical (MEM) devices on a wafer scale
US7186293B2 (en) * 2005-03-23 2007-03-06 Bpsi Holdings, Inc. Agglomerated starch compositions
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
US20060251723A1 (en) * 2005-05-05 2006-11-09 Gao Julia Z Formulations of a SRC/ABL inhibitor
DK1916995T4 (da) * 2005-07-29 2022-10-03 Stichting Groningen Centre For Drug Res Ph-styret, pulserende indgivelsessystem, fremgangsmåder til fremstilling og anvendelse deraf
PE20070698A1 (es) * 2005-11-14 2007-08-17 Teijin Pharma Ltd Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol
US9138414B1 (en) 2006-09-15 2015-09-22 Delavau Llc Calcium supplement having enhanced absorption
BRPI0718579B1 (pt) 2006-11-07 2016-10-18 Procter & Gamble composição ingerível, extrudada, na forma de uma goma de mascar compreendendo um componente de fibras
ES2639854T3 (es) 2007-02-01 2017-10-30 Takeda Pharmaceutical Company Limited Preparación de comprimidos sin causar problemas de fabricación de comprimidos
US7767248B2 (en) * 2007-02-02 2010-08-03 Overly Iii Harry J Soft chew confectionary with high fiber and sugar content and method for making same
EP2167049B1 (en) * 2007-06-04 2016-08-31 Shear/Kershman Laboratories, Inc. Tamper resistant lipid-based oral dosage form for opioid agonists
US8420700B1 (en) * 2008-06-04 2013-04-16 James M. Bausch Tamper resistant lipid-based oral dosage form for sympathomimetic amines
DE102008037324A1 (de) * 2008-08-11 2010-02-18 Ratiopharm Gmbh Pharmazeutische Formulierung zur pulmonalen Blutdrucksenkung
JP2012508713A (ja) * 2008-11-17 2012-04-12 ビーエーエスエフ ソシエタス・ヨーロピア デンプン含有顆粒製剤
NZ600256A (en) 2009-12-02 2014-05-30 Aptalis Pharma Ltd Fexofenadine microcapsules and compositions containing them
WO2011085181A1 (en) * 2010-01-08 2011-07-14 Eurand, Inc. Taste masked topiramate composition and an orally disintegrating tablet comprising the same
TWI564008B (zh) 2010-09-30 2017-01-01 鹽野義製藥股份有限公司 難溶性藥物之溶解性改善製劑
EP2802311B1 (en) * 2011-10-25 2018-12-12 Expermed S.A. Sublingual pharmaceutical composition containing an antihistamine agent and method for the preparation thereof
WO2014016671A2 (en) 2012-07-27 2014-01-30 Redhill Biopharma Ltd. Formulations and methods of manufacturing formulations for use in colonic evacuation
JP2019529534A (ja) * 2016-09-07 2019-10-17 セルジーン コーポレイション 錠剤組成物

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3402240A (en) 1957-06-25 1968-09-17 Pfizer & Co C Medicinal tablet and process of making same
US3039922A (en) 1959-08-17 1962-06-19 Carter Prod Inc Method of administering tablets having decongestant and anti-histaminic activity
US3147187A (en) 1962-09-10 1964-09-01 Don Hall Lab Sustained release pharmaceutical
US3622673A (en) 1968-11-14 1971-11-23 Upjohn Co 4-(1,4,5,6-TETRAHYDROZEPINO 4,5-b INDOL-3(2H)-YL-BUTYROPHENON COMPOSITIONS AND PROCESS OF TREATMENT MENTAL OR EMOTIONAL DISORDERS
DE1931910B2 (de) 1969-06-24 1974-11-28 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Herstellung fester, steuerbar resorbierbarer Arzneimittelzubereitungen schwer löslicher Wirkstoffe
US3968211A (en) 1974-02-11 1976-07-06 The Upjohn Company Compositions and methods of use of amidines for anti-arrhythmic purposes
US3961056A (en) 1974-02-11 1976-06-01 The Upjohn Company Substituted morpholine guanidines for the treatment of arrhythmic conditions
JPS5438167B2 (ru) * 1974-04-27 1979-11-19
US4048331A (en) 1974-10-15 1977-09-13 The Upjohn Company Process of treatment
US3969504A (en) 1975-02-14 1976-07-13 The Upjohn Co. 6-Phenyl benzodiazepine antidepressants
US4148878A (en) 1977-12-23 1979-04-10 Nelson Research & Development Company Inhibition of platelet aggregation with selected phosphoric acid esters
US4148879A (en) 1977-12-23 1979-04-10 Nelson Research & Development Company Inhibition of platelet aggregation with selected phosphonic and phosphinic acid esters
US4327080A (en) 1981-07-13 1982-04-27 E. R. Squibb & Sons, Inc. Novel Bendroflumethiazide formulations and method
JPS58144316A (ja) 1982-02-18 1983-08-27 Chiyoda Yakuhin Kk 安定なインドメタシン錠
US4508726A (en) 1982-09-16 1985-04-02 The Upjohn Company Treatment of panic disorders with alprazolam
ZA841044B (en) 1983-02-17 1984-09-26 Merrell Dow Pharma Dry mix cellulose ether compositions as bulk laxatives
US4517179A (en) 1983-04-29 1985-05-14 Pennwalt Corporation Rapid dissolving, uniform drug compositions and their preparation
JPS6028915A (ja) 1983-07-26 1985-02-14 Eisai Co Ltd ユビデカレノン高含量含有組成物
US4476134A (en) 1983-08-01 1984-10-09 The Upjohn Company Process for treating panic disorders
SE8601624D0 (sv) 1986-04-11 1986-04-11 Haessle Ab New pharmaceutical preparations
IT1200178B (it) 1986-07-23 1989-01-05 Alfa Farmaceutici Spa Formulazioni galeniche a cessione programmata contenenti farmaci ad attivita' antiflogistica
JPH0618774B2 (ja) 1986-10-09 1994-03-16 塩野義製薬株式会社 糖衣錠の製造方法
WO1988004292A1 (en) 1986-12-11 1988-06-16 The Upjohn Company Antipsychotic amino-polyhydro-benz-(iso)quinolines and intermediates
JPS63222112A (ja) 1987-03-10 1988-09-16 Nippon Soda Co Ltd 徐放性顆粒
JPS63280023A (ja) 1987-05-11 1988-11-17 Yoshitomi Pharmaceut Ind Ltd 抗リウマチ薬
NO883326L (no) 1987-08-11 1989-02-13 Bayer Ag Dhp-retard-tilberedning.
JPH01168619A (ja) 1987-12-24 1989-07-04 Takada Seiyaku Kk 新規な酢酸クロルマジノン固形製剤
US4866046A (en) 1988-05-31 1989-09-12 Top Laboratories, Inc. Low-dosage sublingual aspirin
US5292520A (en) 1990-09-13 1994-03-08 Akzo N.V. Stabilized solid pharmaceutical composition containing acid addition salts of a basic drug and an alkaline stabilizer
DK0487774T3 (da) 1990-11-29 1994-11-21 Wei Ming Pharmaceutical Mfg Co Hjælpestof til direkte tablettering
JPH0515319A (ja) 1990-12-14 1993-01-26 Sunstar Inc 水難溶性塩類の分散法およびそれを分散してなる飲用組成物
US5403593A (en) * 1991-03-04 1995-04-04 Sandoz Ltd. Melt granulated compositions for preparing sustained release dosage forms
JPH05139973A (ja) 1991-11-20 1993-06-08 Shin Etsu Chem Co Ltd ニフエジピン含有固形製剤の製造方法
US5534262A (en) 1992-01-10 1996-07-09 Dobrotvorsky; Anatoly E. Pharmaceutical granulated composition and method for preparing same
EP0639567A1 (en) * 1992-05-08 1995-02-22 Otsuka Pharmaceutical Factory, Inc. Indole derivative
IT1255522B (it) 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
DE4333190C2 (de) 1993-09-29 1996-05-30 Korsatko Werner Univ Prof Dr E Zerbeißtablette mit verzögerter Wirkstoff-Freisetzung
US5496884A (en) 1993-11-12 1996-03-05 Lord Corporation Aqueous adhesive for bonding elastomers
TW355683B (en) * 1994-02-17 1999-04-11 Janssen Pharmaceutica Nv Composition containing micronized nebivolol
JPH07267850A (ja) 1994-03-28 1995-10-17 Eisai Co Ltd 不快味を防止した医薬組成物及びその製造方法
US5543099A (en) 1994-09-29 1996-08-06 Hallmark Pharmaceutical, Inc. Process to manufacture micronized nifedipine granules for sustained release medicaments
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
AR016827A1 (es) * 1997-08-22 2001-08-01 Smithkline Beecham Corp PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
AR017512A1 (es) 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas

Also Published As

Publication number Publication date
UA70926C2 (ru) 2004-11-15
KR20010023198A (ko) 2001-03-26
CO4960646A1 (es) 2000-09-25
US20030049315A1 (en) 2003-03-13
EA003663B1 (ru) 2003-08-28
CA2301132A1 (en) 1999-03-04
CN1276718A (zh) 2000-12-13
PL338786A1 (en) 2000-11-20
AU9114698A (en) 1999-03-16
BR9811987A (pt) 2000-09-05
US6372253B1 (en) 2002-04-16
HUP0003186A3 (en) 2001-04-28
AR049057A2 (es) 2006-06-21
EP1014949A4 (en) 2006-06-21
EP1014949A1 (en) 2000-07-05
CA2301132C (en) 2007-11-13
MY137768A (en) 2009-03-31
JP2001513546A (ja) 2001-09-04
AR016827A1 (es) 2001-08-01
HUP0003186A2 (hu) 2001-02-28
WO1999009959A1 (en) 1999-03-04
AR049055A2 (es) 2006-06-21
NZ502890A (en) 2002-03-01
US7132114B2 (en) 2006-11-07
CN1240374C (zh) 2006-02-08
AU745682B2 (en) 2002-03-28
TWI228421B (en) 2005-03-01

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU