AR049057A2 - Una tableta rapidamente desintegrable para la administracion por via oral - Google Patents

Una tableta rapidamente desintegrable para la administracion por via oral

Info

Publication number
AR049057A2
AR049057A2 ARP050102065A ARP050102065A AR049057A2 AR 049057 A2 AR049057 A2 AR 049057A2 AR P050102065 A ARP050102065 A AR P050102065A AR P050102065 A ARP050102065 A AR P050102065A AR 049057 A2 AR049057 A2 AR 049057A2
Authority
AR
Argentina
Prior art keywords
oral route
intragranular
route administration
quickly removable
extragranular
Prior art date
Application number
ARP050102065A
Other languages
English (en)
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of AR049057A2 publication Critical patent/AR049057A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Una tableta rápidamente desintegrable para administracion por vía oral, que comprende un componente intragranular y extragranular, donde el componente intragranular comprende metilcelulosa que tiene una viscosidad de > 1.000 centipoises; y un diluyente seleccionado del grupo que consiste en celulosa microcristalina, almidon de maíz, almidon pregelatinizado, y mezclas de ellos, y opcionalmente un desintegrante intragranular; y un componente extragranular que comprende un agente humectante y un lubricante, y opcionalmente un desintegrante extragranular.
ARP050102065A 1997-08-22 2005-05-19 Una tableta rapidamente desintegrable para la administracion por via oral AR049057A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5689997P 1997-08-22 1997-08-22
US8164498P 1998-04-14 1998-04-14

Publications (1)

Publication Number Publication Date
AR049057A2 true AR049057A2 (es) 2006-06-21

Family

ID=26735830

Family Applications (3)

Application Number Title Priority Date Filing Date
ARP980104077A AR016827A1 (es) 1997-08-22 1998-08-18 PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
ARP050102043A AR049055A2 (es) 1997-08-22 2005-05-18 Una tableta rapidamente desintegrable para la administracion por via oral
ARP050102065A AR049057A2 (es) 1997-08-22 2005-05-19 Una tableta rapidamente desintegrable para la administracion por via oral

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ARP980104077A AR016827A1 (es) 1997-08-22 1998-08-18 PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
ARP050102043A AR049055A2 (es) 1997-08-22 2005-05-18 Una tableta rapidamente desintegrable para la administracion por via oral

Country Status (18)

Country Link
US (2) US6372253B1 (es)
EP (1) EP1014949A4 (es)
JP (1) JP2001513546A (es)
KR (1) KR20010023198A (es)
CN (1) CN1240374C (es)
AR (3) AR016827A1 (es)
AU (1) AU745682B2 (es)
BR (1) BR9811987A (es)
CA (1) CA2301132C (es)
CO (1) CO4960646A1 (es)
EA (1) EA003663B1 (es)
HU (1) HUP0003186A3 (es)
MY (1) MY137768A (es)
NZ (1) NZ502890A (es)
PL (1) PL338786A1 (es)
TW (1) TWI228421B (es)
UA (1) UA70926C2 (es)
WO (1) WO1999009959A1 (es)

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AR016827A1 (es) * 1997-08-22 2001-08-01 Smithkline Beecham Corp PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
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US7198653B2 (en) 2003-07-31 2007-04-03 Delavau Llc Calcium carbonate granulation
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
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Also Published As

Publication number Publication date
CA2301132A1 (en) 1999-03-04
CN1276718A (zh) 2000-12-13
TWI228421B (en) 2005-03-01
CN1240374C (zh) 2006-02-08
EA200000245A1 (ru) 2000-08-28
EP1014949A4 (en) 2006-06-21
HUP0003186A3 (en) 2001-04-28
KR20010023198A (ko) 2001-03-26
WO1999009959A1 (en) 1999-03-04
AR049055A2 (es) 2006-06-21
AR016827A1 (es) 2001-08-01
AU9114698A (en) 1999-03-16
US7132114B2 (en) 2006-11-07
US20030049315A1 (en) 2003-03-13
EA003663B1 (ru) 2003-08-28
BR9811987A (pt) 2000-09-05
CO4960646A1 (es) 2000-09-25
JP2001513546A (ja) 2001-09-04
CA2301132C (en) 2007-11-13
HUP0003186A2 (hu) 2001-02-28
AU745682B2 (en) 2002-03-28
EP1014949A1 (en) 2000-07-05
NZ502890A (en) 2002-03-01
PL338786A1 (en) 2000-11-20
MY137768A (en) 2009-03-31
US6372253B1 (en) 2002-04-16
UA70926C2 (uk) 2004-11-15

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