EA030211B1 - Соединения на основе микрорнк и способы модулирования активности mir-21 - Google Patents

Соединения на основе микрорнк и способы модулирования активности mir-21 Download PDF

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Publication number
EA030211B1
EA030211B1 EA201491953A EA201491953A EA030211B1 EA 030211 B1 EA030211 B1 EA 030211B1 EA 201491953 A EA201491953 A EA 201491953A EA 201491953 A EA201491953 A EA 201491953A EA 030211 B1 EA030211 B1 EA 030211B1
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Eurasian Patent Office
Prior art keywords
nucleoside
nucleosides
modified oligonucleotide
certain embodiments
modified
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EA201491953A
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English (en)
Russian (ru)
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EA201491953A1 (ru
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Балкришен Бхат
Эрик Маркуссон
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Регьюлэс Терапьютикс Инк.
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Application filed by Регьюлэс Терапьютикс Инк. filed Critical Регьюлэс Терапьютикс Инк.
Publication of EA201491953A1 publication Critical patent/EA201491953A1/ru
Publication of EA030211B1 publication Critical patent/EA030211B1/ru

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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EA201491953A 2012-04-25 2013-04-24 Соединения на основе микрорнк и способы модулирования активности mir-21 EA030211B1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261741783P 2012-04-25 2012-04-25
US201261717927P 2012-10-24 2012-10-24
US201361779913P 2013-03-13 2013-03-13
PCT/US2013/037913 WO2013163258A1 (en) 2012-04-25 2013-04-24 Microrna compounds and methods for modulating mir-21 activity

Publications (2)

Publication Number Publication Date
EA201491953A1 EA201491953A1 (ru) 2015-06-30
EA030211B1 true EA030211B1 (ru) 2018-07-31

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EA201491953A EA030211B1 (ru) 2012-04-25 2013-04-24 Соединения на основе микрорнк и способы модулирования активности mir-21

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US (5) US8969317B2 (enExample)
EP (1) EP2841579B1 (enExample)
JP (1) JP6322189B2 (enExample)
KR (4) KR102118429B1 (enExample)
CN (1) CN104254607B (enExample)
AR (1) AR090825A1 (enExample)
AU (1) AU2013251696B2 (enExample)
BR (1) BR112014026639A8 (enExample)
CA (1) CA2869639A1 (enExample)
CL (3) CL2014002844A1 (enExample)
CO (1) CO7111303A2 (enExample)
CR (1) CR20140524A (enExample)
DO (1) DOP2014000233A (enExample)
EA (1) EA030211B1 (enExample)
EC (1) ECSP14028612A (enExample)
GT (1) GT201400221A (enExample)
IL (1) IL234904B (enExample)
IN (1) IN2014DN09134A (enExample)
MX (1) MX353562B (enExample)
MY (1) MY173600A (enExample)
NZ (1) NZ630591A (enExample)
PE (1) PE20142404A1 (enExample)
PH (2) PH12023550488A1 (enExample)
SG (1) SG11201406931XA (enExample)
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UA (1) UA117098C2 (enExample)
WO (1) WO2013163258A1 (enExample)
ZA (1) ZA201407228B (enExample)

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UA116639C2 (uk) 2012-10-09 2018-04-25 Рег'Юлес Терап'Ютікс Інк. Способи лікування синдрому альпорта
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JP2016538829A (ja) 2013-10-03 2016-12-15 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 低密度リポタンパク質受容体をコードするポリヌクレオチド
WO2015061536A1 (en) * 2013-10-25 2015-04-30 Regulus Therapeutics Inc. Microrna compounds and methods for modulating mir-21 activity
CN106459970A (zh) * 2013-11-22 2017-02-22 俞松良 微rna146‑a及其于诊断、治疗及预防小核醣核酸病毒感染的用途及微rna146‑a拮抗剂
JP2017511694A (ja) * 2014-02-12 2017-04-27 トーマス・ジェファーソン・ユニバーシティ マイクロｒｎａ阻害剤を使用するための組成物および方法
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CN105087477A (zh) * 2015-05-21 2015-11-25 王松灵 miR-21反义核苷酸修饰的骨髓间充质干细胞的用途
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