JP6322189B2 - Ｍｉｒ−２１活性を調節するためのマイクロｒｎａ化合物及び方法 - Google Patents

Ｍｉｒ−２１活性を調節するためのマイクロｒｎａ化合物及び方法 Download PDF

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JP6322189B2
JP6322189B2 JP2015509097A JP2015509097A JP6322189B2 JP 6322189 B2 JP6322189 B2 JP 6322189B2 JP 2015509097 A JP2015509097 A JP 2015509097A JP 2015509097 A JP2015509097 A JP 2015509097A JP 6322189 B2 JP6322189 B2 JP 6322189B2
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nucleoside
certain embodiments
mir
fibrosis
nucleosides
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JP2015519891A (ja
JP2015519891A5 (enExample
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バルクリシェン バート
バルクリシェン バート
エリック マーカッソン
エリック マーカッソン
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レグルス セラピューティクス インコーポレイテッド
レグルス セラピューティクス インコーポレイテッド
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JP2015509097A 2012-04-25 2013-04-24 Ｍｉｒ−２１活性を調節するためのマイクロｒｎａ化合物及び方法 Active JP6322189B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261741783P 2012-04-25 2012-04-25
US61/741,783 2012-04-25
US201261717927P 2012-10-24 2012-10-24
US61/717,927 2012-10-24
US201361779913P 2013-03-13 2013-03-13
US61/779,913 2013-03-13
PCT/US2013/037913 WO2013163258A1 (en) 2012-04-25 2013-04-24 Microrna compounds and methods for modulating mir-21 activity

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JP2015519891A JP2015519891A (ja) 2015-07-16
JP2015519891A5 JP2015519891A5 (enExample) 2016-06-09
JP6322189B2 true JP6322189B2 (ja) 2018-05-09

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EP2836219A1 (en) * 2012-04-10 2015-02-18 INSERM - Institut National de la Santé et de la Recherche Médicale Methods for the treatment of nonalcoholic steatohepatitis
IN2014DN09134A (enExample) 2012-04-25 2015-05-22 Regulus Therapeutics Inc
UA116639C2 (uk) 2012-10-09 2018-04-25 Рег'Юлес Терап'Ютікс Інк. Способи лікування синдрому альпорта
EP2906256B1 (en) * 2012-10-12 2018-08-22 Ionis Pharmaceuticals, Inc. Selective antisense compounds and uses thereof
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US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
EP3052106A4 (en) 2013-09-30 2017-07-19 ModernaTX, Inc. Polynucleotides encoding immune modulating polypeptides
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