KR20220028183A - 마이크로rna 화합물 및 mir-21 활성 조절 방법 - Google Patents

마이크로rna 화합물 및 mir-21 활성 조절 방법 Download PDF

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KR20220028183A
KR20220028183A KR1020227006324A KR20227006324A KR20220028183A KR 20220028183 A KR20220028183 A KR 20220028183A KR 1020227006324 A KR1020227006324 A KR 1020227006324A KR 20227006324 A KR20227006324 A KR 20227006324A KR 20220028183 A KR20220028183 A KR 20220028183A
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certain embodiments
nucleoside
mir
subject
modified
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발크리셴 바트
에릭 마르쿠슨
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사노피
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Priority to KR1020237008046A priority Critical patent/KR20230037703A/ko
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KR1020227006324A 2012-04-25 2013-04-24 마이크로rna 화합물 및 mir-21 활성 조절 방법 Ceased KR20220028183A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237008046A KR20230037703A (ko) 2012-04-25 2013-04-24 마이크로rna 화합물 및 mir-21 활성 조절 방법

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201261741783P 2012-04-25 2012-04-25
US61/741,783 2012-04-25
US201261717927P 2012-10-24 2012-10-24
US61/717,927 2012-10-24
US201361779913P 2013-03-13 2013-03-13
US61/779,913 2013-03-13
PCT/US2013/037913 WO2013163258A1 (en) 2012-04-25 2013-04-24 Microrna compounds and methods for modulating mir-21 activity
KR1020207015330A KR102369722B1 (ko) 2012-04-25 2013-04-24 마이크로rna 화합물 및 mir-21 활성 조절 방법

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KR1020237008046A Division KR20230037703A (ko) 2012-04-25 2013-04-24 마이크로rna 화합물 및 mir-21 활성 조절 방법

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KR1020237008046A Ceased KR20230037703A (ko) 2012-04-25 2013-04-24 마이크로rna 화합물 및 mir-21 활성 조절 방법
KR1020227006324A Ceased KR20220028183A (ko) 2012-04-25 2013-04-24 마이크로rna 화합물 및 mir-21 활성 조절 방법
KR1020207015330A Active KR102369722B1 (ko) 2012-04-25 2013-04-24 마이크로rna 화합물 및 mir-21 활성 조절 방법
KR1020147032508A Active KR102118429B1 (ko) 2012-04-25 2013-04-24 마이크로rna 화합물 및 mir-21 활성 조절 방법

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KR1020147032508A Active KR102118429B1 (ko) 2012-04-25 2013-04-24 마이크로rna 화합물 및 mir-21 활성 조절 방법

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US (5) US8969317B2 (enExample)
EP (1) EP2841579B1 (enExample)
JP (1) JP6322189B2 (enExample)
KR (4) KR20230037703A (enExample)
CN (1) CN104254607B (enExample)
AR (1) AR090825A1 (enExample)
AU (1) AU2013251696B2 (enExample)
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UA (1) UA117098C2 (enExample)
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RS63430B1 (sr) 2010-10-01 2022-08-31 Modernatx Inc Ribonukleinske kiseline koje sadrže n1-metil-pseudouracile i njihove primene
EP2691101A2 (en) 2011-03-31 2014-02-05 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
CA3165397A1 (en) 2011-04-25 2012-11-01 Sanofi Microrna compounds and methods for modulating mir-21 activity
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
DK3682905T3 (da) 2011-10-03 2022-02-28 Modernatx Inc Modificerede nukleosider, nukleotider og nukleinsyrer og anvendelser deraf
DE12858350T1 (de) 2011-12-16 2021-10-07 Modernatx, Inc. Modifizierte mrna zusammensetzungen
US9878056B2 (en) 2012-04-02 2018-01-30 Modernatx, Inc. Modified polynucleotides for the production of cosmetic proteins and peptides
HK1206601A1 (en) 2012-04-02 2016-01-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of biologics and proteins associated with human disease
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9193971B2 (en) * 2012-04-10 2015-11-24 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods for the treatment of nonalcoholic steatohepatitis
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