EA025852B1 - ТЕРАПЕВТИЧЕСКИЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ РИЛПИВИРИН HCl И ТЕНОФОВИРА ДИЗОПРОКСИЛФУМАРАТ - Google Patents
ТЕРАПЕВТИЧЕСКИЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ РИЛПИВИРИН HCl И ТЕНОФОВИРА ДИЗОПРОКСИЛФУМАРАТ Download PDFInfo
- Publication number
- EA025852B1 EA025852B1 EA201390651A EA201390651A EA025852B1 EA 025852 B1 EA025852 B1 EA 025852B1 EA 201390651 A EA201390651 A EA 201390651A EA 201390651 A EA201390651 A EA 201390651A EA 025852 B1 EA025852 B1 EA 025852B1
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- EA
- Eurasian Patent Office
- Prior art keywords
- layer
- tablet
- tablet according
- rilpivirin
- microcrystalline cellulose
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Classifications
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- A—HUMAN NECESSITIES
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- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A61P31/18—Antivirals for RNA viruses for HIV
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| EA201691695A EA201691695A1 (ru) | 2010-11-19 | 2011-11-18 | Терапевтические композиции, содержащие рилпивирин hcl и тенофовира дизопроксилфумарат |
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| TWI471145B (zh) | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
| CA2818097C (en) | 2010-11-19 | 2019-07-30 | Janssen R & D Ireland | Therapeutic compositions comprising rilpivirine hcl and tenofovir disoproxil fumarate |
| TWI516499B (zh) | 2011-08-16 | 2016-01-11 | 吉李德科學股份有限公司 | 泰諾福韋（ｔｅｎｏｆｏｖｉｒ）亞拉芬醯胺（ａｌａｆｅｎａｍｉｄｅ）之半反式丁烯二酸鹽 |
| CA2779052A1 (en) * | 2012-05-31 | 2013-11-30 | Pharmascience Inc. | Pharmaceutical composition of entecavir and process of manufacturing |
| AU2013361401C1 (en) | 2012-12-21 | 2018-08-09 | Gilead Sciences, Inc. | Polycyclic-carbamoylpyridone compounds and their pharmaceutical use |
| EP2832351A1 (en) * | 2013-07-29 | 2015-02-04 | Sanovel Ilac Sanayi ve Ticaret A.S. | Multilayer Tablet Formulations Comprising Tenofovir and Entecavir |
| CZ2013985A3 (cs) * | 2013-12-09 | 2015-06-17 | Zentiva, K.S. | Stabilní farmaceutická kompozice obsahující tenofovir disoproxil fumarát |
| WO2015152433A1 (en) * | 2014-03-31 | 2015-10-08 | Hanmi Pharm. Co., Ltd. | Amorphous solid dispersion comprising paclitaxel, tablet comprising the same, and method for preparing the same |
| CN118286245A (zh) | 2014-12-26 | 2024-07-05 | 埃莫里大学 | N4-羟基胞苷和衍生物及与其相关的抗病毒用途 |
| US9839212B2 (en) | 2015-04-16 | 2017-12-12 | Bio-Lab, Inc. | Multicomponent and multilayer compacted tablets |
| KR20170003063A (ko) * | 2015-06-30 | 2017-01-09 | 한미약품 주식회사 | 테노포비어 디소프록실 함유 경구용 고형제제 및 그 제조방법 |
| CA2921336A1 (en) * | 2015-06-30 | 2016-12-30 | Gilead Sciences, Inc. | Pharmaceutical formulations |
| CA2948021C (en) * | 2015-11-09 | 2024-06-18 | Gilead Sciences, Inc. | Pharmaceutical formulations of (2r,5s,13 ar)-8hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzy1)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1'2':4,5]pyrazino [2,1-b][1,3] oxazepine-10-carboxamide |
| EP3439639A1 (en) * | 2016-04-08 | 2019-02-13 | Shionogi & Co., Ltd. | Stabilized solid dosage form |
| TR201617448A2 (tr) * | 2016-11-29 | 2018-06-21 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Tenofovi̇r ve emtri̇si̇tabi̇n i̇çeren kati oral farmasöti̇k bi̇leşi̇mler |
| US10561614B2 (en) * | 2017-01-27 | 2020-02-18 | Steerlife India Private Limited | Tenofovir granules |
| EP3645003A4 (en) * | 2017-06-30 | 2021-03-10 | VIIV Healthcare Company | COMBINATION AND USES AND TREATMENTS THEREOF |
| US11331331B2 (en) | 2017-12-07 | 2022-05-17 | Emory University | N4-hydroxycytidine and derivatives and anti-viral uses related thereto |
| CA3144534A1 (en) * | 2019-07-03 | 2021-01-07 | Janssen Sciences Ireland Unlimited Company | Methods of treating hiv in pediatric patients with rilpivirine |
| CN112137981A (zh) * | 2020-11-02 | 2020-12-29 | 成都晶富医药科技有限公司 | 富马酸丙酚替诺福韦片及其制备工艺 |
| WO2024211882A1 (en) * | 2023-04-07 | 2024-10-10 | Navinta, Llc | Stable compositions of rilpivirine hcl in combination with other anti-retroviral agents |
| CN119174735A (zh) * | 2024-09-03 | 2024-12-24 | 安徽贝克生物制药有限公司 | 一种含利匹韦林的复方片及制备方法 |
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| WO2009106960A2 (en) | 2008-02-27 | 2009-09-03 | Aurobindo Pharma Limited | Stable compositions of lamivudine, tenofovir and efavirenz |
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| WO2005021001A1 (en) * | 2003-09-03 | 2005-03-10 | Tibotec Pharmaceuticals Ltd. | Combinations of a pyrimidine containing nnrti with rt inhibitors |
| WO2006135933A2 (en) * | 2005-06-13 | 2006-12-21 | Bristol-Myers Squibb & Gilead Sciences, Llc | Stable fixed-dose unitary formulations containing tenofovir, a surfactant, efavirenz and emtricitabine |
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| REPORTED BY JULES LEVIN: "Bioequivalence of the Co-Formulation of Emtricitabine/Rilpivirine/Tenofovir DF", XVIII INTERNATIONAL AIDS CONFERENCE, JULY 18-23, 2010, VIENNA, AUSTRIA, 18 July 2010 (2010-07-18), XP009151549, Retrieved from the Internet <URL:http://www.natap.org/2010/IAS/IAS_99.htm> [retrieved on 20110825] * |
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