EA016595B1 - Способ модулирования рецептора gpr119, сопряженного с g-белком, и используемые при этом соединения - Google Patents

Способ модулирования рецептора gpr119, сопряженного с g-белком, и используемые при этом соединения Download PDF

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EA016595B1
EA016595B1 EA201000211A EA201000211A EA016595B1 EA 016595 B1 EA016595 B1 EA 016595B1 EA 201000211 A EA201000211 A EA 201000211A EA 201000211 A EA201000211 A EA 201000211A EA 016595 B1 EA016595 B1 EA 016595B1
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Prior art keywords
compounds
formula
compound
agents
diabetes
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EA201000211A
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English (en)
Russian (ru)
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EA201000211A1 (ru
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Дин А. Уокер
Карен А. Росси
Инг Ванг
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Бристол-Маерс Сквибб Компани
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Publication of EA201000211A1 publication Critical patent/EA201000211A1/ru
Publication of EA016595B1 publication Critical patent/EA016595B1/ru

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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
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    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

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  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
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EA201000211A 2007-07-17 2008-07-16 Способ модулирования рецептора gpr119, сопряженного с g-белком, и используемые при этом соединения EA016595B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95016207P 2007-07-17 2007-07-17
PCT/US2008/070103 WO2009012277A1 (en) 2007-07-17 2008-07-16 Method for modulating gpr119 g protein-coupled receptor and selected compounds

Publications (2)

Publication Number Publication Date
EA201000211A1 EA201000211A1 (ru) 2010-06-30
EA016595B1 true EA016595B1 (ru) 2012-06-29

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EA201000211A EA016595B1 (ru) 2007-07-17 2008-07-16 Способ модулирования рецептора gpr119, сопряженного с g-белком, и используемые при этом соединения
EA201000210A EA018709B1 (ru) 2007-07-17 2008-07-16 Пиридоновые агонисты сопряженного с g-белком рецептора gpr119

Family Applications After (1)

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EA201000210A EA018709B1 (ru) 2007-07-17 2008-07-16 Пиридоновые агонисты сопряженного с g-белком рецептора gpr119

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Country Link
US (6) US7928230B2 (OSRAM)
EP (2) EP2173737B1 (OSRAM)
JP (3) JP5301539B2 (OSRAM)
KR (2) KR20100051814A (OSRAM)
CN (3) CN101801956B (OSRAM)
AR (2) AR067568A1 (OSRAM)
AT (2) ATE524460T1 (OSRAM)
AU (2) AU2008276057B2 (OSRAM)
BR (2) BRPI0814428A2 (OSRAM)
CA (2) CA2693444A1 (OSRAM)
CL (2) CL2008002110A1 (OSRAM)
CO (1) CO6160315A2 (OSRAM)
CY (2) CY1112151T1 (OSRAM)
DK (2) DK2170864T3 (OSRAM)
EA (2) EA016595B1 (OSRAM)
ES (2) ES2371515T3 (OSRAM)
HR (2) HRP20110806T1 (OSRAM)
IL (1) IL228120A0 (OSRAM)
NZ (2) NZ582664A (OSRAM)
PE (2) PE20090888A1 (OSRAM)
PL (2) PL2170864T3 (OSRAM)
PT (2) PT2170864E (OSRAM)
SI (2) SI2170864T1 (OSRAM)
TW (2) TW200904440A (OSRAM)
WO (2) WO2009012275A1 (OSRAM)
ZA (2) ZA201000151B (OSRAM)

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