DZ799A1 - Composés bicycliques substitués. - Google Patents

Composés bicycliques substitués.

Info

Publication number
DZ799A1
DZ799A1 DZ850130A DZ850130A DZ799A1 DZ 799 A1 DZ799 A1 DZ 799A1 DZ 850130 A DZ850130 A DZ 850130A DZ 850130 A DZ850130 A DZ 850130A DZ 799 A1 DZ799 A1 DZ 799A1
Authority
DZ
Algeria
Prior art keywords
alkyl
formula
compounds
substituted bicyclic
stereoisomers
Prior art date
Application number
DZ850130A
Other languages
English (en)
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Application granted granted Critical
Publication of DZ799A1 publication Critical patent/DZ799A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DZ850130A 1984-06-20 1985-06-18 Composés bicycliques substitués. DZ799A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/622,421 US4617307A (en) 1984-06-20 1984-06-20 Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors

Publications (1)

Publication Number Publication Date
DZ799A1 true DZ799A1 (fr) 2004-09-13

Family

ID=24494112

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ850130A DZ799A1 (fr) 1984-06-20 1985-06-18 Composés bicycliques substitués.

Country Status (31)

Country Link
US (1) US4617307A (fr)
EP (1) EP0165904B1 (fr)
JP (1) JPS6112688A (fr)
KR (1) KR900008566B1 (fr)
AT (1) ATE62415T1 (fr)
AU (1) AU589565B2 (fr)
BG (7) BG60262B1 (fr)
CA (1) CA1276633C (fr)
CS (1) CS268672B2 (fr)
CY (1) CY1750A (fr)
DD (1) DD237510A5 (fr)
DE (1) DE3582452D1 (fr)
DK (1) DK170302B1 (fr)
DZ (1) DZ799A1 (fr)
ES (6) ES8702406A1 (fr)
FI (1) FI80694C (fr)
GR (1) GR851487B (fr)
HK (1) HK23494A (fr)
HU (1) HU202529B (fr)
IE (1) IE58070B1 (fr)
IL (1) IL75546A (fr)
MA (1) MA20459A1 (fr)
MX (1) MX9203369A (fr)
NO (1) NO162467C (fr)
NZ (1) NZ212483A (fr)
PH (1) PH23390A (fr)
PL (6) PL145103B1 (fr)
PT (1) PT80661B (fr)
RO (1) RO92583A (fr)
SU (6) SU1433413A3 (fr)
ZA (1) ZA854615B (fr)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
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US5428160A (en) * 1982-12-21 1995-06-27 Ciba-Geigy Corporation Substituted imidazo[5-a]pyridine derviatives and other substituted bicyclic derivatives
US4889861A (en) * 1982-12-21 1989-12-26 Ciba-Geigy Corp. Substituted imidazo[1,5-a]pyridine derivatives and other substituted bicyclic derivatives and their use as aromatase inhibitors
US4728645A (en) * 1982-12-21 1988-03-01 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors
GB8510541D0 (en) * 1985-04-25 1985-05-30 Wyeth John & Brother Ltd Heterocyclic compounds
US5171858A (en) * 1985-06-05 1992-12-15 Schering A.G. Preparation of certain 5,6-dihydro-8-phenyl-imidazo[1,5-a]pyridines
US4749713A (en) * 1986-03-07 1988-06-07 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US4978672A (en) * 1986-03-07 1990-12-18 Ciba-Geigy Corporation Alpha-heterocyclc substituted tolunitriles
US4937250A (en) * 1988-03-07 1990-06-26 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US4797411A (en) * 1986-07-18 1989-01-10 Farmitalia Carlo Erba S.P.A. Cycloalkyl-substituted 4-pyridyl derivatives and use as aromatase inhibitors
GB8820730D0 (en) * 1988-09-02 1988-10-05 Erba Carlo Spa Substituted 5 6 7 8-tetrahydroimidazo/1.5-a/pyridines & process for their preparation
US5057521A (en) * 1988-10-26 1991-10-15 Ciba-Geigy Corporation Use of bicyclic imidazole compounds for the treatment of hyperaldosteronism
US5066656A (en) * 1989-11-01 1991-11-19 Janssen Pharmaceutica N.V. Pharmacologically active (6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)- and (5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl) substituted 1H-benzotriazole derivatives
CA2026792A1 (fr) * 1989-11-01 1991-05-02 Michael N. Greco Derives de substitution (6,7-dihydro-5h-pyrrolo[1,2-c]imidazol-5-yl) et (5,6,7,8-tetrahydro-imidazo[1,5-a]pyridin-5-yl) du 1h-benzotriazole
MTP1076B (en) * 1990-01-12 1991-09-30 Ciba Geigy Ag Hemihydrate
US5162337A (en) * 1990-10-05 1992-11-10 Merck & Co., Inc. Animal growth promotion
CA2066369A1 (fr) * 1991-04-19 1992-10-20 Alex Elbrecht Methode de regulation des caracteristiques chez les poissons
CH683151A5 (de) * 1991-04-24 1994-01-31 Ciba Geigy Ag Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
JPH05176659A (ja) * 1991-04-26 1993-07-20 Merck & Co Inc 家禽における雌性表現型を転換するために抗ミュラー管ホルモンを単独またはアロマターゼ阻害剤と組合せて使用する方法
AU2356195A (en) * 1994-04-14 1995-11-10 Sepracor, Inc. Treating estrogen-dependent diseases with (-)-fadrozole
AU682947B2 (en) * 1994-05-27 1997-10-23 Mochida Pharmaceutical Co., Ltd. Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity
DE4432106A1 (de) * 1994-09-09 1996-03-14 Hoechst Ag Mit Heterocyclen-N-Oxid-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum, sie enthaltendes Medikament sowie Zwischenprodukte zu ihrer Herstellung
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US8168616B1 (en) 2000-11-17 2012-05-01 Novartis Ag Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension
EP1534265B1 (fr) * 2002-07-30 2006-11-22 Novartis AG Combinaison d'un inhibiteur de l'aromatase et d'un biphosphonate
JP4533139B2 (ja) * 2002-08-07 2010-09-01 ノバルティス アーゲー アルドステロン介在性病状の処置用剤としての有機化合物
ES2305520T3 (es) * 2002-11-18 2008-11-01 Novartis Ag Derivados de imidazo(1,5a)piridina y metodos para tratar enfermedades mediadas por aldosterona.
WO2005007627A1 (fr) * 2003-07-18 2005-01-27 Nihon Nohyaku Co., Ltd. Derive de phenylpyridine, produit intermediaire correspondant, et herbicide contenant ledit derive de phenylpyridine en tant qu'ingredient actif
GB0327839D0 (en) 2003-12-01 2003-12-31 Novartis Ag Organic compounds
EP1977741A3 (fr) 2004-03-17 2009-10-14 Novartis AG Utilisation d'inhibiteurs de la rénine en thérapie
BRPI0510410A (pt) * 2004-05-28 2007-10-23 Speedel Experimenta Ag compostos orgánicos
AR049125A1 (es) * 2004-05-28 2006-06-28 Speedel Experimenta Ag Heterociclos biciclicos nitrogenados inhibidores de la aromatasa.
GT200600381A (es) * 2005-08-25 2007-03-28 Compuestos organicos
EP1842543A1 (fr) 2006-04-05 2007-10-10 Speedel Pharma AG Composition pharmaceutique comprennant un inhibiteur de l'aldosteron synthase et un antagoniste de recepteur mineralcorticoide
BRPI0712557A2 (pt) * 2006-05-26 2013-07-02 Novartis Ag inibidores de aldosterona sintase e/ou 11 beta-hidrolase
KR101149274B1 (ko) 2006-07-20 2012-05-29 노파르티스 아게 Ｃετρ 억제제로서의 아미노-피페리딘 유도체
EP2057163A1 (fr) * 2006-08-25 2009-05-13 Novartis AG Dérivés d'imidazole fusionnés destinés à traiter les troubles médiés par l'aldostérone synthase et/ou par 11-beta-hydroxylase et/ou aromatase
US20090325936A1 (en) * 2006-12-20 2009-12-31 Bilodeau Mark T Imidazopyridine analogs as cb2 receptor modulators, useful in the treatment of pain, respiratory and non-respiratory diseases
AU2008324243B2 (en) 2007-11-05 2012-03-08 Novartis Ag 4-benzylamino-1-carboxyacyl-piperidine derivatives as CETP inhibitors useful for the treatment of diseases such as hyperlipidemia or arteriosclerosis
EP2229356B1 (fr) 2007-12-03 2011-10-12 Novartis AG Dérivés de 4-benzylaminopyrrolidine 1,2-disubstituée comme inhibiteurs de cetp utiles pour le traitement de maladies telles que l'hyperlipidémie ou l'artériosclérose
EP2095819A1 (fr) * 2008-02-28 2009-09-02 Maastricht University Dérivés de N-benzyle imidazole et leur utilisation comme inhibiteurs de l'aldosterone synthase
ME01923B (me) 2009-05-28 2015-05-20 Novartis Ag Supstituisani derivati aminopropionske kiseline kao inhibitori neprilizina
MX2011012627A (es) 2009-05-28 2011-12-14 Novartis Ag Derivados aminobutiricos sustituidos como inhibidores de nepralisina.
JO2967B1 (en) 2009-11-20 2016-03-15 نوفارتس ايه جي Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
US8673974B2 (en) 2010-11-16 2014-03-18 Novartis Ag Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
US8877815B2 (en) 2010-11-16 2014-11-04 Novartis Ag Substituted carbamoylcycloalkyl acetic acid derivatives as NEP
TWI518073B (zh) 2011-06-14 2016-01-21 美國禮來大藥廠 醛固酮合成酶抑制劑
PT2729142T (pt) 2011-07-08 2018-10-01 Novartis Ag Método de tratamento de aterosclerose em sujeitos com nível elevado de triglicéridos
KR20140141687A (ko) * 2012-01-17 2014-12-10 노파르티스 아게 디히드로피롤로[1,2-c]이미다졸릴 알도스테론 신타제 또는 아로마타제 억제제의 신규 형태 및 염
UY35144A (es) 2012-11-20 2014-06-30 Novartis Ag Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
TR201808541T4 (tr) 2013-02-14 2018-07-23 Novartis Ag Nep (nötr endopeptidaz) inhibitörleri olarak ikame edilmiş bisfenil butanoik fosfonik asit türevleri.
CN105705167A (zh) 2013-07-25 2016-06-22 诺华股份有限公司 合成的apelin多肽的生物缀合物
CN105612172A (zh) 2013-07-25 2016-05-25 诺华股份有限公司 用于治疗心力衰竭的环状多肽
SG11201704758XA (en) 2015-01-23 2017-08-30 Novartis Ag Synthetic apelin fatty acid conjugates with improved half-life
US10556869B2 (en) * 2015-01-29 2020-02-11 Novartis Ag Process for the production of condensed imidazolo derivatives
GB201511790D0 (en) 2015-07-06 2015-08-19 Iomet Pharma Ltd Pharmaceutical compound
JP2016074729A (ja) * 2015-12-31 2016-05-12 国立大学法人 千葉大学 イミダゾリウム塩及びそれを用いた不斉合成触媒並びにイミダゾリウム塩の製造方法
JOP20190086A1 (ar) 2016-10-21 2019-04-18 Novartis Ag مشتقات نافثيريدينون جديدة واستخدامها في معالجة عدم انتظام ضربات القلب
WO2018078049A1 (fr) 2016-10-27 2018-05-03 Damian Pharma Ag Inhibiteur de l'aldostérone synthase
US10822332B2 (en) * 2016-10-27 2020-11-03 Damian Pharma Ag Aldosterone synthase inhibitor
UY38072A (es) 2018-02-07 2019-10-01 Novartis Ag Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos
MX2020011471A (es) 2018-05-03 2020-12-07 Damian Pharma Ag R-fadrozol para usar en el tratamiento de aldosteronismo.
WO2020110008A1 (fr) 2018-11-27 2020-06-04 Novartis Ag Composés pentamères cycliques servant d'inhibiteurs de proprotéine convertase subtilisine/kexine de type 9 (pcsk9) pour le traitement d'un trouble métabolique
UY38485A (es) 2018-11-27 2020-06-30 Novartis Ag Compuestos tetrámeros cíclicos como inhibidores de proproteína convertasa subtilisina/kexina tipo 9 (pcsk9), método de tratamiento, uso y su preparación
JP2022509184A (ja) 2018-11-27 2022-01-20 ノバルティス アーゲー 代謝性障害の処置のためのプロタンパク質コンバターゼスブチリシン／ケキシン９型（ｐｃｓｋ９）阻害剤としての環状ペプチド
WO2023084449A1 (fr) 2021-11-12 2023-05-19 Novartis Ag Dérivés diaminocyclopentylpyridines pour le traitement d'une maladie ou d'un trouble

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JPS5124517B1 (fr) * 1971-03-15 1976-07-24
FR2449689A1 (fr) * 1979-02-20 1980-09-19 Logeais Labor Jacques Nouveaux derives condenses de pyrrolidine ou de piperidine, leur procede de preparation et leurs applications en therapeutique
GB2101595B (en) * 1981-06-22 1985-05-30 Ciba Geigy Ag Substituted imidazo(1,5-a)pyridines, process for their manufacture, pharmaceutical preparations containing these compounds and their therapeutic application
US4444775A (en) * 1981-06-22 1984-04-24 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridines
US4409226A (en) * 1981-10-05 1983-10-11 Schering Corporation Imidazo[1,5-a]pyridines
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US4470986A (en) * 1982-12-21 1984-09-11 Ciba-Geigy Corporation Certain imidazo (1,5-A) pyridine aliphatic carboxylic acid derivatives and their use as selective thromboxane inhibitors
US4588732A (en) * 1982-12-21 1986-05-13 Ciba-Geigy Corporation Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors

Also Published As

Publication number Publication date
HU202529B (en) 1991-03-28
AU589565B2 (en) 1989-10-19
US4617307A (en) 1986-10-14
SU1443802A3 (ru) 1988-12-07
ES8801262A1 (es) 1987-12-16
ES555542A0 (es) 1988-03-16
FI852399L (fi) 1985-12-21
PL145087B1 (en) 1988-08-31
HUT37936A (en) 1986-03-28
IE58070B1 (en) 1993-06-30
CS268672B2 (en) 1990-04-11
PL254099A1 (en) 1986-09-09
ATE62415T1 (de) 1991-04-15
BG60402B2 (bg) 1995-02-28
PL145814B1 (en) 1988-11-30
ES8800681A1 (es) 1987-11-16
KR900008566B1 (ko) 1990-11-24
DK170302B1 (da) 1995-07-31
CA1276633C (fr) 1990-11-20
BG60262B2 (en) 1994-03-31
BG60306B2 (bg) 1994-07-25
BG60353B2 (bg) 1994-11-30
BG60352B2 (bg) 1994-11-30
BG60305B2 (bg) 1994-07-25
ES555541A0 (es) 1987-11-16
ES8702406A1 (es) 1987-01-01
PT80661A (en) 1985-07-01
FI80694C (fi) 1990-07-10
SU1436879A3 (ru) 1988-11-07
SU1436880A3 (ru) 1988-11-07
PL145104B1 (en) 1988-08-31
SU1433413A3 (ru) 1988-10-23
PT80661B (en) 1987-05-04
DK277685A (da) 1985-12-21
SU1482530A3 (ru) 1989-05-23
IL75546A0 (en) 1985-10-31
JPS6112688A (ja) 1986-01-21
ES8802049A1 (es) 1988-03-16
BG60262B1 (bg) 1994-03-31
GR851487B (fr) 1985-11-25
DK277685D0 (da) 1985-06-19
ES8802048A1 (es) 1988-03-16
CY1750A (en) 1994-06-03
EP0165904A2 (fr) 1985-12-27
ZA854615B (en) 1986-02-26
NO162467C (no) 1990-01-10
IE851520L (en) 1985-12-20
ES544344A0 (es) 1987-01-01
DE3582452D1 (de) 1991-05-16
IL75546A (en) 1990-01-18
PL145103B1 (en) 1988-08-31
MX9203369A (es) 1992-09-01
ES8802155A1 (es) 1988-04-01
NO852474L (no) 1985-12-23
DD237510A5 (de) 1986-07-16
MA20459A1 (fr) 1985-12-31
PL145348B1 (en) 1988-09-30
ES555539A0 (es) 1988-04-01
EP0165904B1 (fr) 1991-04-10
RO92583A (fr) 1987-11-30
JPH047746B2 (fr) 1992-02-12
FI80694B (fi) 1990-03-30
HK23494A (en) 1994-03-25
ES555540A0 (es) 1987-12-16
PL145105B1 (en) 1988-08-31
SU1436878A3 (ru) 1988-11-07
NO162467B (no) 1989-09-25
BG60307B2 (en) 1994-07-25
EP0165904A3 (en) 1987-09-09
AU4385785A (en) 1986-01-02
KR860000299A (ko) 1986-01-27
CS444985A2 (en) 1989-07-12
FI852399A0 (fi) 1985-06-17
PH23390A (en) 1989-07-26
ES555538A0 (es) 1988-03-16
NZ212483A (en) 1988-10-28

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