DK277685A - Substituerede imidazo(1,5-a)pyridinderivater og salte deraf samt deres fremstilling og anvendelse - Google Patents

Substituerede imidazo(1,5-a)pyridinderivater og salte deraf samt deres fremstilling og anvendelse Download PDF

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DK277685A
DK277685A DK277685A DK277685A DK277685A DK 277685 A DK277685 A DK 277685A DK 277685 A DK277685 A DK 277685A DK 277685 A DK277685 A DK 277685A DK 277685 A DK277685 A DK 277685A
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alkyl
salts
preparation
pyridine derivatives
formula
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DK277685A
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DK277685D0 (da
DK170302B1 (da
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Leslie J Browne
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Ciba Geigy Ag
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
DK277685A 1984-06-20 1985-06-19 Substituerede imidazo[1,5-a]pyridinderivater og deres 7,8-dihydro- og 5,6,7,8-tetrahydroderivater samt 5H-5-(4-cyanophenyl)-6,7-dihydropyrrolo[1,2-c]imidazol-derivater og salte deraf, en fremgangsmåde til deres fremstilling, deres anvendelse til fremstilling af farmaceutiske præparater samt farmaceutiske præparater med indhold deraf DK170302B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/622,421 US4617307A (en) 1984-06-20 1984-06-20 Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors
US62242184 1984-06-20

Publications (3)

Publication Number Publication Date
DK277685D0 DK277685D0 (da) 1985-06-19
DK277685A true DK277685A (da) 1985-12-21
DK170302B1 DK170302B1 (da) 1995-07-31

Family

ID=24494112

Family Applications (1)

Application Number Title Priority Date Filing Date
DK277685A DK170302B1 (da) 1984-06-20 1985-06-19 Substituerede imidazo[1,5-a]pyridinderivater og deres 7,8-dihydro- og 5,6,7,8-tetrahydroderivater samt 5H-5-(4-cyanophenyl)-6,7-dihydropyrrolo[1,2-c]imidazol-derivater og salte deraf, en fremgangsmåde til deres fremstilling, deres anvendelse til fremstilling af farmaceutiske præparater samt farmaceutiske præparater med indhold deraf

Country Status (31)

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US (1) US4617307A (da)
EP (1) EP0165904B1 (da)
JP (1) JPS6112688A (da)
KR (1) KR900008566B1 (da)
AT (1) ATE62415T1 (da)
AU (1) AU589565B2 (da)
BG (7) BG60262B2 (da)
CA (1) CA1276633C (da)
CS (1) CS268672B2 (da)
CY (1) CY1750A (da)
DD (1) DD237510A5 (da)
DE (1) DE3582452D1 (da)
DK (1) DK170302B1 (da)
DZ (1) DZ799A1 (da)
ES (6) ES8702406A1 (da)
FI (1) FI80694C (da)
GR (1) GR851487B (da)
HK (1) HK23494A (da)
HU (1) HU202529B (da)
IE (1) IE58070B1 (da)
IL (1) IL75546A (da)
MA (1) MA20459A1 (da)
MX (1) MX9203369A (da)
NO (1) NO162467C (da)
NZ (1) NZ212483A (da)
PH (1) PH23390A (da)
PL (6) PL145814B1 (da)
PT (1) PT80661B (da)
RO (1) RO92583A (da)
SU (6) SU1433413A3 (da)
ZA (1) ZA854615B (da)

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SU1482530A3 (ru) 1989-05-23
DE3582452D1 (de) 1991-05-16
IL75546A (en) 1990-01-18
BG60262B1 (bg) 1994-03-31
FI80694C (fi) 1990-07-10
FI80694B (fi) 1990-03-30
HUT37936A (en) 1986-03-28
PL145103B1 (en) 1988-08-31
BG60307B2 (en) 1994-05-27
NO852474L (no) 1985-12-23
GR851487B (da) 1985-11-25
FI852399L (fi) 1985-12-21
SU1443802A3 (ru) 1988-12-07
ES8802048A1 (es) 1988-03-16
EP0165904A2 (de) 1985-12-27
ES8801262A1 (es) 1987-12-16
NZ212483A (en) 1988-10-28
DK277685D0 (da) 1985-06-19
ES8802049A1 (es) 1988-03-16
PL145814B1 (en) 1988-11-30
SU1433413A3 (ru) 1988-10-23
IL75546A0 (en) 1985-10-31
MX9203369A (es) 1992-09-01
AU589565B2 (en) 1989-10-19
ES544344A0 (es) 1987-01-01
EP0165904A3 (en) 1987-09-09
NO162467B (no) 1989-09-25
BG60402B2 (bg) 1995-02-28
BG60305B2 (bg) 1994-05-27
DD237510A5 (de) 1986-07-16
JPH047746B2 (da) 1992-02-12
RO92583A (ro) 1987-11-30
BG60262B2 (en) 1994-03-31
KR860000299A (ko) 1986-01-27
DZ799A1 (fr) 2004-09-13
ES555539A0 (es) 1988-04-01
PH23390A (en) 1989-07-26
SU1436878A3 (ru) 1988-11-07
FI852399A0 (fi) 1985-06-17
MA20459A1 (fr) 1985-12-31
ES555538A0 (es) 1988-03-16
ES8800681A1 (es) 1987-11-16
IE58070B1 (en) 1993-06-30
PT80661A (en) 1985-07-01
PL145104B1 (en) 1988-08-31
SU1436880A3 (ru) 1988-11-07
PL145105B1 (en) 1988-08-31
BG60306B2 (bg) 1994-05-27
EP0165904B1 (de) 1991-04-10
BG60353B2 (bg) 1994-08-15
CA1276633C (en) 1990-11-20
CS268672B2 (en) 1990-04-11
ES555540A0 (es) 1987-12-16
CY1750A (en) 1994-06-03
CS444985A2 (en) 1989-07-12
PL145087B1 (en) 1988-08-31
KR900008566B1 (ko) 1990-11-24
ES555542A0 (es) 1988-03-16
DK170302B1 (da) 1995-07-31
PL254099A1 (en) 1986-09-09
SU1436879A3 (ru) 1988-11-07
AU4385785A (en) 1986-01-02
IE851520L (en) 1985-12-20
ATE62415T1 (de) 1991-04-15
JPS6112688A (ja) 1986-01-21
HK23494A (en) 1994-03-25
ES8802155A1 (es) 1988-04-01
ES555541A0 (es) 1987-11-16
ES8702406A1 (es) 1987-01-01
BG60352B2 (bg) 1994-08-15
US4617307A (en) 1986-10-14
ZA854615B (en) 1986-02-26
PT80661B (en) 1987-05-04
NO162467C (no) 1990-01-10
PL145348B1 (en) 1988-09-30
HU202529B (en) 1991-03-28

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