DK342489A - Fremgangsmaade og mellemprodukter til syntese af l-(-)-2-amino-3-(3,4-dihydroxyphenyl)-propionsyre - Google Patents

Fremgangsmaade og mellemprodukter til syntese af l-(-)-2-amino-3-(3,4-dihydroxyphenyl)-propionsyre Download PDF

Info

Publication number
DK342489A
DK342489A DK342489A DK342489A DK342489A DK 342489 A DK342489 A DK 342489A DK 342489 A DK342489 A DK 342489A DK 342489 A DK342489 A DK 342489A DK 342489 A DK342489 A DK 342489A
Authority
DK
Denmark
Prior art keywords
dihydroxyphenyl
intermediates
synthesis
amino
propionic acid
Prior art date
Application number
DK342489A
Other languages
English (en)
Other versions
DK342489D0 (da
DK172106B1 (da
Inventor
Vincenzo Cannata
Giancarlo Tamerlani
Mauro Morotti
Original Assignee
Mini Ricerca Scient Tecnolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mini Ricerca Scient Tecnolog filed Critical Mini Ricerca Scient Tecnolog
Publication of DK342489D0 publication Critical patent/DK342489D0/da
Publication of DK342489A publication Critical patent/DK342489A/da
Application granted granted Critical
Publication of DK172106B1 publication Critical patent/DK172106B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/34—Preparation of optical isomers by separation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
    • C07C255/43—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms the carbon skeleton being further substituted by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK342489A 1988-07-12 1989-07-11 Ny fremgangsmåde og mellemprodukter og anvendelse heraf til syntese af levodopa DK172106B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2132288 1988-07-12
IT8821322A IT1226902B (it) 1988-07-12 1988-07-12 Processo per la sintesi del levodopa

Publications (3)

Publication Number Publication Date
DK342489D0 DK342489D0 (da) 1989-07-11
DK342489A true DK342489A (da) 1990-01-13
DK172106B1 DK172106B1 (da) 1997-10-27

Family

ID=11180092

Family Applications (1)

Application Number Title Priority Date Filing Date
DK342489A DK172106B1 (da) 1988-07-12 1989-07-11 Ny fremgangsmåde og mellemprodukter og anvendelse heraf til syntese af levodopa

Country Status (23)

Country Link
US (1) US4962223A (da)
EP (1) EP0357565B1 (da)
JP (1) JP2507069B2 (da)
KR (1) KR960004185B1 (da)
AR (1) AR248267A1 (da)
AT (1) ATE111439T1 (da)
AU (1) AU615083B2 (da)
CA (1) CA1338672C (da)
DD (1) DD284674A5 (da)
DE (1) DE68918207T2 (da)
DK (1) DK172106B1 (da)
ES (1) ES2063837T3 (da)
FI (1) FI101534B1 (da)
HU (1) HU203318B (da)
IE (1) IE65956B1 (da)
IL (1) IL90844A0 (da)
IT (1) IT1226902B (da)
NO (1) NO174293C (da)
NZ (1) NZ229910A (da)
PL (1) PL160103B1 (da)
PT (1) PT91144B (da)
YU (1) YU47907B (da)
ZA (1) ZA895255B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459145A (en) * 1988-01-19 1995-10-17 Pfizer Inc. Calcium independent camp phosphodiesterase inhibitor antidepressant
IT1226903B (it) * 1988-07-12 1991-02-21 Mini Ricerca Scient Tecnolog Processo per la sintesi di aminoacidi otticamente attivi
US5395935A (en) * 1992-05-08 1995-03-07 Pfizer Inc. Endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents
DE19502967A1 (de) * 1995-01-31 1996-08-01 Basf Ag Verfahren zur Racemattrennung von 2-Aryl-2-omega-alkylaminoalkannitrilen
JP3634207B2 (ja) * 1999-09-14 2005-03-30 独立行政法人科学技術振興機構 光学活性なα−アミノニトリル並びにα−アミノ酸類の製造方法
US20040002615A1 (en) * 2002-06-28 2004-01-01 Allen David Robert Preparation of chiral amino-nitriles
AU2003282603A1 (en) * 2002-10-11 2004-05-04 Depomed Development Ltd Gastro-retentive levodopa delivery form
DE10261807A1 (de) 2002-12-19 2004-07-01 Turicum Drug Development Ag Deuterierte Catecholaminderivate sowie diese Verbindungen enthaltende Arzneimittel
WO2004069146A2 (en) * 2003-02-07 2004-08-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem L-dopa amide derivatives and uses thereof
EA017983B1 (ru) 2006-02-17 2013-04-30 Бедс Фарма Гмбх Беролина Инновейтив Ресёч Энд Девелопмент Сёвисиз Дейтерированные производные катехоламина и лекарственные средства, содержащие указанные соединения
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
MX2016011837A (es) 2014-03-13 2017-04-27 Neuroderm Ltd Composiciones de inhibidores de la dopa decarboxilasa.
BR112021005955A2 (pt) 2018-09-28 2021-07-27 Griffith University agentes e métodos para modular atividade de patógeno
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA504449A (en) * 1954-07-20 C. Britton Edgar Alpha-amino-beta-alkoxy-butyronitriles and method of making same
BE638485A (da) * 1962-10-11
US3845076A (en) * 1971-04-20 1974-10-29 Sagami Chem Res Method of preparing aldehydes
JPS4920305A (da) * 1972-06-21 1974-02-22
HU165026B (da) * 1972-08-11 1974-06-28
US4072698A (en) * 1976-12-02 1978-02-07 The Upjohn Company Resolution of aminonitriles
YU93877A (en) * 1977-04-08 1982-06-30 Krka Process for the resolution of racemic alpha-aminonitrils
IL59048A (en) * 1979-12-27 1984-01-31 Plantex Ltd Process for the preparation of alpha-amino-3-phenyl-propionitriles and novel benzylidene amino acetonitriles as intermediates therefor
DE3002543A1 (de) * 1980-01-25 1981-07-30 Basf Ag, 6700 Ludwigshafen 4-tert.-butoxyphenylglycinnitril sowie verfahren zur herstellung von d-(-)- und l-(+)-4-hydroxyphenylglycin
JPS56115749A (en) * 1980-02-18 1981-09-11 Sagami Chem Res Center Dopa derivative
JPS61275253A (ja) * 1985-05-30 1986-12-05 Nippon Kayaku Co Ltd ３−（３，４−ジヒドロキシフエニル）−２−メチルアラニンの製造法
FR2614626B1 (fr) * 1987-04-30 1989-07-21 Ranoux Claude Conteneur pour fecondation des ovocytes et replacement des embryons chez l'homme et l'animal

Also Published As

Publication number Publication date
JP2507069B2 (ja) 1996-06-12
IE65956B1 (en) 1995-11-29
IT1226902B (it) 1991-02-21
AR248267A1 (es) 1995-07-12
CA1338672C (en) 1996-10-22
AU615083B2 (en) 1991-09-19
FI893368A0 (fi) 1989-07-11
HUT51596A (en) 1990-05-28
ES2063837T3 (es) 1995-01-16
YU139989A (en) 1990-12-31
DE68918207D1 (de) 1994-10-20
FI893368A (fi) 1990-01-13
NO892861D0 (no) 1989-07-11
DE68918207T2 (de) 1995-05-11
KR960004185B1 (ko) 1996-03-27
DD284674A5 (de) 1990-11-21
JPH02231457A (ja) 1990-09-13
DK342489D0 (da) 1989-07-11
IE892227L (en) 1990-01-12
AU3805789A (en) 1990-01-25
NZ229910A (en) 1991-04-26
EP0357565A3 (en) 1991-09-25
IT8821322A0 (it) 1988-07-12
PL160103B1 (pl) 1993-02-26
IL90844A0 (en) 1990-02-09
ZA895255B (en) 1990-04-25
KR900001641A (ko) 1990-02-27
DK172106B1 (da) 1997-10-27
ATE111439T1 (de) 1994-09-15
EP0357565A2 (en) 1990-03-07
FI101534B (fi) 1998-07-15
EP0357565B1 (en) 1994-09-14
NO174293C (no) 1994-04-13
US4962223A (en) 1990-10-09
PT91144B (pt) 1995-01-31
NO892861L (no) 1990-01-15
FI101534B1 (fi) 1998-07-15
NO174293B (no) 1994-01-03
YU47907B (sh) 1996-05-20
PT91144A (pt) 1990-02-08
HU203318B (en) 1991-07-29

Similar Documents

Publication Publication Date Title
DK342489D0 (da) Fremgangsmaade og mellemprodukter til syntese af l-(-)-2-amino-3-(3,4-dihydroxyphenyl)-propionsyre
IT8222682A0 (it) Nastro adesivo e procedimento per la sua produzione.
DK137083D0 (da) Fremgangsmade til fremstilling af 26,26,26,27,27,27-hexafluorlalfa,25-dihydroxycholecalciferol og mellemprodukter til brug herved
IT1176856B (it) Metodo per la sintesi di iodobenzene
DK0505222T3 (da) Fremgangsmåde til frysning
FI97860B (fi) Menetelmä sydänsykkeen häiriösietoiseksi mittaamiseksi
IT1176981B (it) Metodo per la sintesi di iodobenzene
IT1218463B (it) Apparato perfezionato per la fabricazione di chiaccio
DK90594A (da) Fremgangsmåde til fremstilling af 3,4,5,6-tetrafluorbenzoesyre
DK195585A (da) 4'-deschlorrebeccamycin og fremgangsmaade til fremstilling af samme
DK565482A (da) Fremgangsmaade til fremstilling af 1,1-alkandiol-dicarboxylsyreestere, og mellemprodukter for disse estere
DK436685D0 (da) Fremgangsmaade til fremstilling af 2,4-dichlor-5-fluor-benzoesyre
DK551684D0 (da) Fremgangsmaade til fremstilling af substituerede og usubstituerede 2-((1-carbamoyl-1,2-dimethylpropyl)-carbamoyl)-3-quinolincarboxyl-,-nicotin- og -benzoesyrer
DK127182A (da) Fremgangsmaade til fremstilling af 1,1-dioxopenicillanoyloxymethyl-6-(2-phenylacetamido)penicillanater og mellemprodukter herved
DK162997C (da) Fremgangsmaade til fremstilling af 5,6,7,8-tetrahydrofolinsyre
IT8548954A0 (it) Metodo per la sintesi di dna a catena lunga
IT8534025V0 (it) Elemento d'aggancio.
FI962592A0 (fi) Uudet välituotteet keinotekoisina makeutusaineina käyttökelpoisten L-aspartyyli-D-alfa-aminoalkanoyyli-(S)-N-alfa-alkyylibentsyyliamidien syntetisoimiseksi
IT8521136A0 (it) Procedimento per la preparazione di o-nitro benzaldeide.
IT8967002A0 (it) Procedimento per la separazione di miscele metanolo metilmetacrilato
DK280389D0 (da) Fremgangsmaade til syntese af desferrioxamin b og analoger dertil
DK356889A (da) Fremgangsmaade til hydrocarbonylering af halogenerede aromatiske forbindelser
IT1186719B (it) Metodo per la sintesi del fenolo
DK160819C (da) Fremgangsmaade til fremstilling af 3,5-dichlor-2-pyridon
DK0389876T3 (da) Hidtil ukendt fremgangsmåde til syntese af N-methyl-3,4-dimethoxyphenylethylamin

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed