DK3365364T5 - Kimære antistof/T-celle-receptorkonstruktioner og anvendelser deraf - Google Patents

Kimære antistof/T-celle-receptorkonstruktioner og anvendelser deraf Download PDF

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Publication number
DK3365364T5
DK3365364T5 DK16858388.8T DK16858388T DK3365364T5 DK 3365364 T5 DK3365364 T5 DK 3365364T5 DK 16858388 T DK16858388 T DK 16858388T DK 3365364 T5 DK3365364 T5 DK 3365364T5
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cell receptor
chimeric antibody
receptor constructs
constructs
chimeric
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DK16858388.8T
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Danish (da)
English (en)
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DK3365364T3 (da
Inventor
Hong Liu
Yiyang Xu
Su Yan
Jingwei Lu
Zhiyuan Yang
Cheng Liu
Vivien Wai-Fan Chan
Lucas Horan
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Eureka Therapeutics Inc
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
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    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • C07K16/2809Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C07K16/2833Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
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DK16858388.8T 2015-10-23 2016-10-21 Kimære antistof/T-celle-receptorkonstruktioner og anvendelser deraf DK3365364T5 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562245944P 2015-10-23 2015-10-23
US201662304918P 2016-03-07 2016-03-07
US201662345649P 2016-06-03 2016-06-03
US201662369694P 2016-08-01 2016-08-01
PCT/US2016/058305 WO2017070608A1 (en) 2015-10-23 2016-10-21 Antibody/t-cell receptor chimeric constructs and uses thereof

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DK3365364T3 DK3365364T3 (da) 2024-05-06
DK3365364T5 true DK3365364T5 (da) 2024-09-30

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US (7) US11421013B2 (https=)
EP (2) EP3842450A1 (https=)
JP (3) JP7316042B2 (https=)
KR (2) KR102777395B1 (https=)
CN (4) CN107614519B (https=)
AU (2) AU2016342041B2 (https=)
CA (1) CA3001137A1 (https=)
DK (1) DK3365364T5 (https=)
ES (1) ES2979220T3 (https=)
IL (3) IL258405B (https=)
MX (1) MX2018004721A (https=)
MY (1) MY194628A (https=)
PH (1) PH12018500861A1 (https=)
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SG (3) SG10201913245UA (https=)
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SI3227339T1 (sl) 2014-12-05 2022-02-28 Memorial Sloan-Kettering Cancer Center Himerni antigenski receptorji, ki ciljajo na receptor, povezan z G-proteinom, in njihova uporaba
EP3227324A4 (en) * 2014-12-05 2018-08-29 Memorial Sloan Kettering Cancer Center Antibodies targeting g-protein coupled receptor and methods of use
CN107995913B (zh) 2015-05-18 2022-02-11 T细胞受体治疗公司 使用融合蛋白对tcr重编程的组合物和方法
EP3842450A1 (en) * 2015-10-23 2021-06-30 Eureka Therapeutics, Inc. Antibody/t-cell receptor chimeric constructs and uses thereof
GB201604458D0 (en) 2016-03-16 2016-04-27 Immatics Biotechnologies Gmbh Peptides and combination of peptides for use in immunotherapy against cancers
EP3448987A4 (en) 2016-04-29 2020-05-27 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
EP4596707A3 (en) 2016-09-19 2025-10-08 University of Southern California Non-radioactive cytotoxicity assays
CN110352068A (zh) * 2016-12-02 2019-10-18 南加利福尼亚大学 合成的免疫受体及其使用方法
IL270138B2 (en) 2017-04-26 2025-08-01 Eureka Therapeutics Inc Structures that specifically recognize glypican 3 and their uses
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