DK3023788T3 - Sammensætninger af tumorspecifikke neoantigener til anvendelse ved behandling af tumorer - Google Patents
Sammensætninger af tumorspecifikke neoantigener til anvendelse ved behandling af tumorer Download PDFInfo
- Publication number
- DK3023788T3 DK3023788T3 DK15198284.0T DK15198284T DK3023788T3 DK 3023788 T3 DK3023788 T3 DK 3023788T3 DK 15198284 T DK15198284 T DK 15198284T DK 3023788 T3 DK3023788 T3 DK 3023788T3
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- DK
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- Prior art keywords
- tumors
- tumor
- compositions
- treatment
- specific neoantigens
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A61K39/0011—Cancer antigens
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Hospice & Palliative Care (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33486610P | 2010-05-14 | 2010-05-14 | |
| EP11781409.5A EP2569633B1 (en) | 2010-05-14 | 2011-05-16 | Compositions and methods of identifying tumor specific neoantigens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3023788T3 true DK3023788T3 (da) | 2020-04-27 |
Family
ID=44915022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15198284.0T DK3023788T3 (da) | 2010-05-14 | 2011-05-16 | Sammensætninger af tumorspecifikke neoantigener til anvendelse ved behandling af tumorer |
Country Status (14)
| Country | Link |
|---|---|
| US (8) | US9115402B2 (OSRAM) |
| EP (4) | EP3699266B1 (OSRAM) |
| JP (5) | JP5948319B2 (OSRAM) |
| KR (4) | KR102017898B1 (OSRAM) |
| CN (2) | CN105648056A (OSRAM) |
| AU (1) | AU2011252795B2 (OSRAM) |
| BR (2) | BR122021014039B1 (OSRAM) |
| CA (2) | CA2797868C (OSRAM) |
| DK (1) | DK3023788T3 (OSRAM) |
| ES (3) | ES2564841T3 (OSRAM) |
| HU (1) | HUE049886T2 (OSRAM) |
| PL (1) | PL3023788T3 (OSRAM) |
| PT (1) | PT3023788T (OSRAM) |
| WO (1) | WO2011143656A2 (OSRAM) |
Families Citing this family (178)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10347710B4 (de) | 2003-10-14 | 2006-03-30 | Johannes-Gutenberg-Universität Mainz | Rekombinante Impfstoffe und deren Verwendung |
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| US9732131B2 (en) | 2006-02-27 | 2017-08-15 | Calviri, Inc. | Identification and use of novopeptides for the treatment of cancer |
| WO2011028531A1 (en) | 2009-08-24 | 2011-03-10 | Baylor College Of Medicine | Generation of ctl lines with specificity against multiple tumor antigens or multiple viruses |
| PT3023788T (pt) * | 2010-05-14 | 2020-05-18 | Massachusetts Gen Hospital | Composições de neoantigénios específicos de tumor para utilização no tratamento de tumores |
| EP4223311B1 (en) * | 2011-05-24 | 2025-06-25 | BioNTech SE | Individualized vaccines for cancer |
| HRP20230443T1 (hr) * | 2011-05-24 | 2023-09-15 | BioNTech SE | Individualizirana cjepiva protiv raka |
| EP2757153B1 (en) * | 2011-08-02 | 2019-07-03 | The University of Tokyo | Method for assessing myelodysplastic syndrome or myeloid tumor predisposition, polypeptide and antibody therefor, and candidate screening method for therapeutic drug or prophylactic drug therefor |
| EP2761299B1 (en) * | 2011-09-29 | 2016-10-26 | Trovagene, Inc. | Mutations in sf3b1 and chronic lymphocytic leukemia |
| WO2013086464A1 (en) * | 2011-12-07 | 2013-06-13 | The Broad Institute, Inc. | Markers associated with chronic lymphocytic leukemia prognosis and progression |
| GB201121308D0 (en) | 2011-12-12 | 2012-01-25 | Cell Medica Ltd | Process |
| PT2812431T (pt) | 2012-02-09 | 2019-10-18 | Baylor College Medicine | Pepmixes para gerar ctls multivirais com larga especifidade |
| WO2013143555A1 (en) | 2012-03-26 | 2013-10-03 | Biontech Ag | Rna formulation for immunotherapy |
| WO2013177593A2 (en) | 2012-05-25 | 2013-11-28 | Phosimmune, Inc. | Identification of mhc class i phospho-peptide antigens from breast cancer utilizing shla technology and complementary enrichment strategies |
| JP2015533473A (ja) * | 2012-07-12 | 2015-11-26 | ペルシミューン,インコーポレイテッド | 個別のがんワクチン及び適応免疫細胞療法 |
| GB201214007D0 (en) * | 2012-08-07 | 2012-09-19 | Scancell Ltd | Anti-tumour immune responses to modified self-epitopes |
| US9561266B2 (en) | 2012-08-31 | 2017-02-07 | University Of Virginia Patent Foundation | Target peptides for immunotherapy and diagnostics |
| EP2892544A4 (en) | 2012-09-05 | 2016-11-02 | Univ Virginia Patent Found | TARGET PEPTIDES FOR THERAPY AND DIAGNOSIS OF COLORECTAL CARCINOMAS |
| ES2737757T3 (es) | 2012-09-28 | 2020-01-15 | Univ Connecticut | Identificación de epítopos protectores contra tumores para el tratamiento de cánceres |
| AU2013351542B2 (en) | 2012-11-28 | 2018-08-09 | BioNTech SE | Individualized vaccines for cancer |
| GB2508414A (en) * | 2012-11-30 | 2014-06-04 | Max Delbrueck Centrum | Tumour specific T cell receptors (TCRs) |
| ES2649180T3 (es) | 2013-02-22 | 2018-01-10 | Curevac Ag | Combinación de vacunación e inhibición de la ruta PD-1 |
| EP3292873B1 (en) | 2013-02-22 | 2019-05-01 | CureVac AG | Combination of vaccination and inhibition of the pd-1 pathway |
| CA2906514C (en) | 2013-03-14 | 2021-07-27 | Jonathan Schneck | Nanoscale artificial antigen presenting cells |
| KR102341899B1 (ko) * | 2013-04-07 | 2021-12-21 | 더 브로드 인스티튜트, 인코퍼레이티드 | 개인맞춤화 신생물 백신을 위한 조성물 및 방법 |
| WO2014180490A1 (en) | 2013-05-10 | 2014-11-13 | Biontech Ag | Predicting immunogenicity of t cell epitopes |
| US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
| WO2015077717A1 (en) | 2013-11-25 | 2015-05-28 | The Broad Institute Inc. | Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status |
| US11725237B2 (en) | 2013-12-05 | 2023-08-15 | The Broad Institute Inc. | Polymorphic gene typing and somatic change detection using sequencing data |
| KR102429859B1 (ko) * | 2013-12-06 | 2022-08-04 | 더 브로드 인스티튜트, 인코퍼레이티드 | 신생물 백신을 위한 제형 |
| EP3082853A2 (en) * | 2013-12-20 | 2016-10-26 | The Broad Institute, Inc. | Combination therapy with neoantigen vaccine |
| SG10201805674YA (en) * | 2014-01-02 | 2018-08-30 | Memorial Sloan Kettering Cancer Center | Determinants of cancer response to immunotherapy |
| EP3590529A1 (en) | 2014-03-12 | 2020-01-08 | CureVac AG | Combination of vaccination and ox40 agonists |
| AU2015247727A1 (en) | 2014-04-15 | 2016-11-03 | University Of Virginia Patent Foundation | Isolated T cell receptors and methods of use therefor |
| WO2016040682A1 (en) | 2014-09-10 | 2016-03-17 | Genentech, Inc. | Immunogenic mutant peptide screening platform |
| EP3191121B1 (en) * | 2014-09-10 | 2020-05-27 | The University of Connecticut | Identification of immunologically protective neo-epitopes for the treatment of cancers |
| US11338026B2 (en) | 2014-09-10 | 2022-05-24 | The University Of Connecticut | Identification of immunologically protective neo-epitopes for the treatment of cancers |
| EP3193892A4 (en) * | 2014-09-14 | 2018-09-12 | Washington University | Personalized cancer vaccines and methods therefor |
| KR20210032011A (ko) | 2014-09-17 | 2021-03-23 | 더 존스 홉킨스 유니버시티 | 항원-특이적 t 세포 식별, 농축, 및/또는 증식을 위한 시약 및 방법 |
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