DK2937418T3 - Compositions and Methods for Inhibiting Transthyretin Expression - Google Patents

Compositions and Methods for Inhibiting Transthyretin Expression Download PDF

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Publication number
DK2937418T3
DK2937418T3 DK15151452.8T DK15151452T DK2937418T3 DK 2937418 T3 DK2937418 T3 DK 2937418T3 DK 15151452 T DK15151452 T DK 15151452T DK 2937418 T3 DK2937418 T3 DK 2937418T3
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dsrna
ttr
rna
seq
nucleotide
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DK15151452.8T
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Danish (da)
English (en)
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Dinah Wen-Yee Sah
Gregory Hinkle
Rene Alvarez
Stuart Milstein
Qingmin Chen
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Alnylam Pharmaceuticals Inc
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    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
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DK15151452.8T 2008-10-20 2009-10-20 Compositions and Methods for Inhibiting Transthyretin Expression DK2937418T3 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US10695608P 2008-10-20 2008-10-20
US11573808P 2008-11-18 2008-11-18
US15667009P 2009-03-02 2009-03-02
US18554509P 2009-06-09 2009-06-09
US24278309P 2009-09-15 2009-09-15
US24479409P 2009-09-22 2009-09-22
EP09810834.3A EP2344639B1 (en) 2008-10-20 2009-10-20 Compositions and methods for inhibiting expression of transthyretin

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Publication Number Publication Date
DK2937418T3 true DK2937418T3 (en) 2018-01-22

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DK15151452.8T DK2937418T3 (en) 2008-10-20 2009-10-20 Compositions and Methods for Inhibiting Transthyretin Expression
DK09810834.3T DK2344639T3 (en) 2008-10-20 2009-10-20 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TRANSTHYRETINE

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DK09810834.3T DK2344639T3 (en) 2008-10-20 2009-10-20 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TRANSTHYRETINE

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US (9) US8168775B2 (enExample)
EP (4) EP2937418B1 (enExample)
JP (7) JP5791505B2 (enExample)
KR (6) KR101624869B1 (enExample)
CN (3) CN106834291B (enExample)
AU (1) AU2009307677C1 (enExample)
CA (3) CA3018487A1 (enExample)
CY (3) CY1116944T1 (enExample)
DK (2) DK2937418T3 (enExample)
EA (3) EA029762B1 (enExample)
ES (2) ES2656516T3 (enExample)
HR (2) HRP20150796T1 (enExample)
HU (3) HUE026604T2 (enExample)
IL (5) IL281434B2 (enExample)
LT (2) LT2937418T (enExample)
LU (1) LUC00098I2 (enExample)
MX (4) MX344354B (enExample)
NL (1) NL300965I2 (enExample)
NO (2) NO2937418T3 (enExample)
NZ (2) NZ592867A (enExample)
PL (2) PL2937418T3 (enExample)
PT (2) PT2937418T (enExample)
SG (3) SG10201912276XA (enExample)
SI (2) SI2344639T1 (enExample)
SM (2) SMT201800027T1 (enExample)
WO (1) WO2010048228A2 (enExample)
ZA (1) ZA201102876B (enExample)

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