DK2845900T3 - PREPARATION OF THERMOLYSIN AND ITS VARIETIES AND USE IN LIQUID DETERGENTS - Google Patents

PREPARATION OF THERMOLYSIN AND ITS VARIETIES AND USE IN LIQUID DETERGENTS Download PDF

Info

Publication number
DK2845900T3
DK2845900T3 DK14189403.0T DK14189403T DK2845900T3 DK 2845900 T3 DK2845900 T3 DK 2845900T3 DK 14189403 T DK14189403 T DK 14189403T DK 2845900 T3 DK2845900 T3 DK 2845900T3
Authority
DK
Denmark
Prior art keywords
thermolysin
sequence
composition
variant
dna
Prior art date
Application number
DK14189403.0T
Other languages
Danish (da)
English (en)
Inventor
David A Estell
Amy D Liu
Ronaldus W J Hommes
Andrew Shaw
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Application granted granted Critical
Publication of DK2845900T3 publication Critical patent/DK2845900T3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38618Protease or amylase in liquid compositions only
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38636Preparations containing enzymes, e.g. protease or amylase containing enzymes other than protease, amylase, lipase, cellulase, oxidase or reductase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24Metalloendopeptidases (3.4.24)
    • C12Y304/24027Thermolysin (3.4.24.27)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Fodder In General (AREA)
DK14189403.0T 2007-11-01 2008-10-28 PREPARATION OF THERMOLYSIN AND ITS VARIETIES AND USE IN LIQUID DETERGENTS DK2845900T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98466407P 2007-11-01 2007-11-01
EP08845951A EP2205732A2 (en) 2007-11-01 2008-10-28 Production of thermolysin and variants thereof and use in liquid detergents

Publications (1)

Publication Number Publication Date
DK2845900T3 true DK2845900T3 (en) 2019-03-04

Family

ID=40345178

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14189403.0T DK2845900T3 (en) 2007-11-01 2008-10-28 PREPARATION OF THERMOLYSIN AND ITS VARIETIES AND USE IN LIQUID DETERGENTS

Country Status (11)

Country Link
US (4) US8569034B2 (enExample)
EP (2) EP2845900B1 (enExample)
JP (4) JP2011502506A (enExample)
KR (1) KR20100075993A (enExample)
CN (2) CN103305493B (enExample)
BR (1) BRPI0818144A2 (enExample)
CA (1) CA2704311C (enExample)
DK (1) DK2845900T3 (enExample)
MX (1) MX2010004326A (enExample)
RU (2) RU2536255C2 (enExample)
WO (1) WO2009058303A2 (enExample)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2704311C (en) * 2007-11-01 2018-02-13 Danisco Us Inc. Production of thermolysin and variants thereof, and use in liquid detergents
US8796009B2 (en) * 2010-06-21 2014-08-05 Toyota Motor Engineering & Manufacturing North America, Inc. Clearcoat containing thermolysin-like protease from Bacillus stearothermophilus for cleaning of insect body stains
MX2013009178A (es) * 2011-02-16 2013-08-29 Novozymes As Composiciones detergentes que comprenden metaloproteasas.
CN103502418A (zh) * 2011-02-16 2014-01-08 诺维信公司 包含金属蛋白酶的去污剂组合物
JP6204459B2 (ja) * 2012-05-18 2017-09-27 アクト コーポレイションAquto Corporation コンテンツ、サービス及びアクセスに対する請求及び課金
WO2014029820A1 (en) 2012-08-22 2014-02-27 Novozymes A/S Detergent compositions comprising metalloproteases
CN104619838A (zh) * 2012-08-22 2015-05-13 诺维信公司 来自微小杆菌属的金属蛋白酶
WO2014071410A1 (en) 2012-11-05 2014-05-08 Danisco Us Inc. Compositions and methods comprising thermolysin protease variants
CN104884079B (zh) * 2012-11-14 2021-02-12 史密夫和内修公司 稳定的嗜热菌蛋白酶水凝胶
CN105452456A (zh) * 2013-05-29 2016-03-30 丹尼斯科美国公司 新型金属蛋白酶
CN105492603B (zh) 2013-05-29 2022-06-03 丹尼斯科美国公司 新型金属蛋白酶
EP3004342B1 (en) * 2013-05-29 2023-01-11 Danisco US Inc. Novel metalloproteases
WO2015066667A1 (en) 2013-11-04 2015-05-07 Danisco Us Inc. Proteases in wheat processing
WO2015066669A1 (en) 2013-11-04 2015-05-07 Danisco Us Inc. Proteases in corn processing
DK3080262T3 (da) 2013-12-13 2019-05-06 Danisco Us Inc Serinproteaser af bacillus-arter
EP3080263B1 (en) 2013-12-13 2019-07-03 Danisco US Inc. Serine proteases of the bacillus gibsonii-clade
WO2015095046A1 (en) 2013-12-16 2015-06-25 E. I. Du Pont De Nemours And Company Use of poly alpha-1,3-glucan ethers as viscosity modifiers
US9957334B2 (en) 2013-12-18 2018-05-01 E I Du Pont De Nemours And Company Cationic poly alpha-1,3-glucan ethers
WO2015123323A1 (en) 2014-02-14 2015-08-20 E. I. Du Pont De Nemours And Company Poly-alpha-1,3-1,6-glucans for viscosity modification
CN106132997A (zh) 2014-03-11 2016-11-16 纳幕尔杜邦公司 作为洗涤剂助洗剂的氧化的聚α‑1,3‑葡聚糖
EP3587569B1 (en) 2014-03-21 2022-08-03 Danisco US Inc. Serine proteases of bacillus species
US9714403B2 (en) 2014-06-19 2017-07-25 E I Du Pont De Nemours And Company Compositions containing one or more poly alpha-1,3-glucan ether compounds
US9771548B2 (en) 2014-06-19 2017-09-26 E I Du Pont De Nemours And Company Compositions containing one or more poly alpha-1,3-glucan ether compounds
WO2016061438A1 (en) 2014-10-17 2016-04-21 Danisco Us Inc. Serine proteases of bacillus species
EP3212781B1 (en) 2014-10-27 2019-09-18 Danisco US Inc. Serine proteases
WO2016069544A1 (en) 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases
WO2016069563A1 (en) * 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases
US20180010074A1 (en) 2014-10-27 2018-01-11 Danisco Us Inc. Serine proteases of bacillus species
DK3212662T3 (da) 2014-10-27 2020-07-20 Danisco Us Inc Serinproteaser
EP3212782B1 (en) 2014-10-27 2019-04-17 Danisco US Inc. Serine proteases
PL3034588T3 (pl) 2014-12-17 2019-09-30 The Procter And Gamble Company Kompozycja detergentu
EP3034597A1 (en) * 2014-12-17 2016-06-22 The Procter and Gamble Company Detergent composition
EP3034596B2 (en) * 2014-12-17 2021-11-10 The Procter & Gamble Company Detergent composition
EP3237631A1 (en) 2014-12-23 2017-11-01 E. I. du Pont de Nemours and Company Enzymatically produced cellulose
CN104546663B (zh) * 2014-12-26 2017-08-25 广州市植美化妆品有限公司 一种含类芽孢杆菌的防脱生发洗发水
GB201501565D0 (en) * 2015-01-30 2015-03-18 Dupont Nutrition Biosci Aps Method
CN107454914B (zh) * 2015-03-12 2021-09-21 丹尼斯科美国公司 包含lg12进化枝蛋白酶变体的组合物和方法
CN107835855B (zh) 2015-05-13 2022-05-13 丹尼斯科美国公司 AprL-进化枝蛋白酶变体及其用途
JP7015695B2 (ja) 2015-06-17 2022-02-03 ダニスコ・ユーエス・インク バチルス・ギブソニイ(Bacillus gibsonii)クレードセリンプロテアーゼ
US20160381076A1 (en) * 2015-06-23 2016-12-29 Avocado Systems Inc. Service level agreements and application defined security policies for application and data security registration
WO2017079756A1 (en) 2015-11-05 2017-05-11 Danisco Us Inc Paenibacillus and bacillus spp. mannanases
EP3371308B1 (en) 2015-11-05 2022-05-11 Danisco US Inc. Paenibacillus sp. mannanases
WO2017083226A1 (en) 2015-11-13 2017-05-18 E. I. Du Pont De Nemours And Company Glucan fiber compositions for use in laundry care and fabric care
EP3374401B1 (en) 2015-11-13 2022-04-06 Nutrition & Biosciences USA 4, Inc. Glucan fiber compositions for use in laundry care and fabric care
WO2017083228A1 (en) 2015-11-13 2017-05-18 E. I. Du Pont De Nemours And Company Glucan fiber compositions for use in laundry care and fabric care
WO2017106676A1 (en) 2015-12-18 2017-06-22 Danisco Us Inc Polypeptides with endoglucanase activity and uses thereof
EP3205393A1 (en) 2016-02-12 2017-08-16 Basf Se Process for preparation of microcapsules
EP3205392A1 (en) 2016-02-12 2017-08-16 Basf Se Microcapsules and process for preparation of microcapsules
WO2017182295A1 (en) 2016-04-18 2017-10-26 Basf Se Liquid cleaning compositions
WO2017192692A1 (en) 2016-05-03 2017-11-09 Danisco Us Inc Protease variants and uses thereof
BR112018072586A2 (pt) 2016-05-05 2019-02-19 Danisco Us Inc variantes de protease e usos das mesmas
CN109477112B (zh) 2016-05-31 2024-09-06 丹尼斯科美国公司 蛋白酶变体及其用途
EP3472313B1 (en) 2016-06-17 2022-08-31 Danisco US Inc. Protease variants and uses thereof
US20190264138A1 (en) 2016-11-07 2019-08-29 Danisco Us Inc. Laundry detergent composition
EP4212622A3 (en) 2016-12-21 2023-11-29 Danisco US Inc. Bacillus gibsonii-clade serine proteases
WO2018118917A1 (en) 2016-12-21 2018-06-28 Danisco Us Inc. Protease variants and uses thereof
WO2018169750A1 (en) 2017-03-15 2018-09-20 Danisco Us Inc Trypsin-like serine proteases and uses thereof
JP7672197B2 (ja) 2017-03-31 2025-05-07 ダニスコ・ユーエス・インク α-アミラーゼ組み合わせ変異体
WO2019026827A1 (ja) * 2017-07-31 2019-02-07 天野エンザイム株式会社 サーモリシン液剤
CN111212906B (zh) 2017-08-18 2024-02-02 丹尼斯科美国公司 α-淀粉酶变体
DE102017219993A1 (de) 2017-11-09 2019-05-09 Henkel Ag & Co. Kgaa Enzymhaltiges Wasch- oder Reinigungsmittel
CN111373039A (zh) 2017-11-29 2020-07-03 丹尼斯科美国公司 具有改善的稳定性的枯草杆菌蛋白酶变体
WO2019245705A1 (en) 2018-06-19 2019-12-26 Danisco Us Inc Subtilisin variants
US12415996B2 (en) 2018-06-19 2025-09-16 Danisco Us Inc. Subtilisin variants
US20230174962A1 (en) 2018-07-31 2023-06-08 Danisco Us Inc Variant alpha-amylases having amino acid substitutions that lower the pka of the general acid
JP7158974B2 (ja) * 2018-09-27 2022-10-24 小林製薬株式会社 義歯洗浄剤
EP3856882A1 (en) 2018-09-27 2021-08-04 Danisco US Inc. Compositions for medical instrument cleaning
EP3864148A2 (en) 2018-10-12 2021-08-18 Danisco US Inc. Alpha-amylases with mutations that improve stability in the presence of chelants
EP3887515A1 (en) 2018-11-28 2021-10-06 Danisco US Inc. Subtilisin variants having improved stability
WO2020242858A1 (en) 2019-05-24 2020-12-03 Danisco Us Inc Subtilisin variants and methods of use
EP3980517A1 (en) 2019-06-06 2022-04-13 Danisco US Inc. Methods and compositions for cleaning
US20220403359A1 (en) 2019-10-24 2022-12-22 Danisco Us Inc Variant maltopentaose/maltohexaose-forming alpha-amylases
CN111876435A (zh) * 2020-07-31 2020-11-03 山东大学 一种海洋嗜热胶原蛋白酶a69及其编码基因与应用
WO2022047149A1 (en) 2020-08-27 2022-03-03 Danisco Us Inc Enzymes and enzyme compositions for cleaning
CN116997642A (zh) 2021-01-29 2023-11-03 丹尼斯科美国公司 清洁组合物及其相关的方法
CN116897160A (zh) 2021-02-22 2023-10-17 丹尼斯科美国公司 在色素缺陷型芽孢杆菌属细胞中产生目的蛋白的方法和组合物
CN117616120A (zh) 2021-06-30 2024-02-27 丹尼斯科美国公司 变体脂肪酶及其用途
WO2023034486A2 (en) 2021-09-03 2023-03-09 Danisco Us Inc. Laundry compositions for cleaning
CA3241094A1 (en) 2021-12-16 2023-06-22 Jonathan LASSILA Variant maltopentaose/maltohexaose-forming alpha-amylases
EP4448751A2 (en) 2021-12-16 2024-10-23 Danisco US Inc. Subtilisin variants and methods of use
CN118715318A (zh) 2021-12-16 2024-09-27 丹尼斯科美国公司 枯草杆菌蛋白酶变体及其用途
EP4448749A2 (en) 2021-12-16 2024-10-23 Danisco US Inc. Subtilisin variants and methods of use
WO2023168234A1 (en) 2022-03-01 2023-09-07 Danisco Us Inc. Enzymes and enzyme compositions for cleaning
CN119487167A (zh) 2022-06-21 2025-02-18 丹尼斯科美国公司 用于清洁的包含具有嗜热菌蛋白酶活性的多肽的组合物和方法
CA3265718A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. VARIANTS OF SUBTILISINE AND ASSOCIATED PROCESSES
JP2025530749A (ja) 2022-09-02 2025-09-17 ダニスコ・ユーエス・インク 洗剤組成物及びそれに関連する方法
CN119816592A (zh) 2022-09-02 2025-04-11 丹尼斯科美国公司 甘露聚糖酶变体和使用方法
EP4615968A1 (en) 2022-11-09 2025-09-17 Danisco US Inc. Subtilisin variants and methods of use
CN116179519B (zh) * 2023-01-18 2024-04-23 天津科技大学 动性球菌来源的蛋白酶及其应用
CN120677237A (zh) 2023-02-01 2025-09-19 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
CN120712348A (zh) 2023-03-06 2025-09-26 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
CN120813242A (zh) 2023-03-16 2025-10-17 营养与生物科学美国第四公司 用于清洁和臭味控制的短芽孢杆菌发酵物提取物及其用途
WO2025071996A1 (en) 2023-09-28 2025-04-03 Danisco Us Inc. Variant cutinase enzymes with improved solubility and uses thereof
WO2025085351A1 (en) 2023-10-20 2025-04-24 Danisco Us Inc. Subtilisin variants and methods of use

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR76237B (enExample) 1981-08-08 1984-08-04 Procter & Gamble
US4561998A (en) 1982-05-24 1985-12-31 The Procter & Gamble Company Near-neutral pH detergents containing anionic surfactant, cosurfactant and fatty acid
US4550862A (en) 1982-11-17 1985-11-05 The Procter & Gamble Company Liquid product pouring and measuring package with self draining feature
US4597898A (en) 1982-12-23 1986-07-01 The Proctor & Gamble Company Detergent compositions containing ethoxylated amines having clay soil removal/anti-redeposition properties
US4515707A (en) 1983-06-27 1985-05-07 The Chemithon Corporation Intermediate product for use in producing a detergent bar and method for producing same
US4515705A (en) 1983-11-14 1985-05-07 The Procter & Gamble Company Compositions containing odor purified proteolytic enzymes and perfumes
US4537706A (en) 1984-05-14 1985-08-27 The Procter & Gamble Company Liquid detergents containing boric acid to stabilize enzymes
US5763257A (en) * 1984-05-29 1998-06-09 Genencor International, Inc. Modified subtilisins having amino acid alterations
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5322770A (en) 1989-12-22 1994-06-21 Hoffman-Laroche Inc. Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription
US4977252A (en) 1988-03-11 1990-12-11 National Starch And Chemical Investment Holding Corporation Modified starch emulsifier characterized by shelf stability
US4968451A (en) 1988-08-26 1990-11-06 The Procter & Gamble Company Soil release agents having allyl-derived sulfonated end caps
US5354559A (en) 1990-05-29 1994-10-11 Grain Processing Corporation Encapsulation with starch hydrolyzate acid esters
JPH05199873A (ja) * 1991-11-28 1993-08-10 Tosoh Corp 新規プロテア−ゼ
JPH05199872A (ja) * 1991-11-28 1993-08-10 Tosoh Corp 新規プロテア−ゼ
JPH0646850A (ja) * 1991-12-16 1994-02-22 Tosoh Corp 新規プロテア−ゼ
EP0616033B1 (en) * 1993-03-17 2001-06-13 Holland Sweetener Company V.O.F. Mutants of a thermostable neutral protease from Bacillus
US5486303A (en) 1993-08-27 1996-01-23 The Procter & Gamble Company Process for making high density detergent agglomerates using an anhydrous powder additive
AU1121495A (en) * 1993-12-07 1995-06-27 Holland Sweetener Company V.O.F. Mutants of a thermostable neutral protease from bacillus
DE4342680A1 (de) 1993-12-15 1995-06-22 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
WO1995020663A2 (en) * 1994-01-27 1995-08-03 Rijksuniversiteit Te Groningen THERMOSTABLE VARIANTS OF NEUTRAL PROTEASES OF BACILLUS STEAROTHERMOPHILUS AND $i(BACILLUS THERMOPROTEOLYTICUS)
JPH07250679A (ja) * 1994-03-14 1995-10-03 Daiwa Kasei Kk 変異型サーモリシンty140及びその遺伝子
PE6995A1 (es) 1994-05-25 1995-03-20 Procter & Gamble Composicion que comprende un polimero de polialquilenoamina etoxilado propoxilado como agente de separacion de sucio
US5879584A (en) 1994-09-10 1999-03-09 The Procter & Gamble Company Process for manufacturing aqueous compositions comprising peracids
US5691297A (en) 1994-09-20 1997-11-25 The Procter & Gamble Company Process for making a high density detergent composition by controlling agglomeration within a dispersion index
US5489392A (en) 1994-09-20 1996-02-06 The Procter & Gamble Company Process for making a high density detergent composition in a single mixer/densifier with selected recycle streams for improved agglomerate properties
US5516448A (en) 1994-09-20 1996-05-14 The Procter & Gamble Company Process for making a high density detergent composition which includes selected recycle streams for improved agglomerate
JPH11501501A (ja) * 1994-12-06 1999-02-09 財団法人 相模中央化学研究所 バチルス由来の熱安定中性プロテアーゼの変異体
US5534179A (en) 1995-02-03 1996-07-09 Procter & Gamble Detergent compositions comprising multiperacid-forming bleach activators
US5574005A (en) 1995-03-07 1996-11-12 The Procter & Gamble Company Process for producing detergent agglomerates from high active surfactant pastes having non-linear viscoelastic properties
JPH09255A (ja) * 1995-04-20 1997-01-07 Daiwa Kasei Kk 変異型サーモリシンyt73及びその遺伝子
US5569645A (en) 1995-04-24 1996-10-29 The Procter & Gamble Company Low dosage detergent composition containing optimum proportions of agglomerates and spray dried granules for improved flow properties
US5597936A (en) 1995-06-16 1997-01-28 The Procter & Gamble Company Method for manufacturing cobalt catalysts
US5565422A (en) 1995-06-23 1996-10-15 The Procter & Gamble Company Process for preparing a free-flowing particulate detergent composition having improved solubility
US5576282A (en) 1995-09-11 1996-11-19 The Procter & Gamble Company Color-safe bleach boosters, compositions and laundry methods employing same
JP4121556B2 (ja) 1995-09-18 2008-07-23 ザ プロクター アンド ギャンブル カンパニー デリバリーシステム
JPH09220090A (ja) * 1995-12-11 1997-08-26 Tosoh Corp 新規なサーモライシン様プロテアーゼ及びその用途
MA24137A1 (fr) 1996-04-16 1997-12-31 Procter & Gamble Fabrication d'agents de surface ramifies .
US5929022A (en) 1996-08-01 1999-07-27 The Procter & Gamble Company Detergent compositions containing amine and specially selected perfumes
CN1263759C (zh) 1997-03-07 2006-07-12 宝洁公司 制备交联桥大环化合物的改进方法
US6306812B1 (en) 1997-03-07 2001-10-23 Procter & Gamble Company, The Bleach compositions containing metal bleach catalyst, and bleach activators and/or organic percarboxylic acids
EP0867512A1 (en) * 1997-03-27 1998-09-30 Rijksuniversiteit te Groningen Improved metallo-endopeptidases from Bacillus stearothermophilus
US6376445B1 (en) 1997-08-14 2002-04-23 Procter & Gamble Company Detergent compositions comprising a mannanase and a protease
US5935826A (en) 1997-10-31 1999-08-10 National Starch And Chemical Investment Holding Corporation Glucoamylase converted starch derivatives and their use as emulsifying and encapsulating agents
CN1279715A (zh) 1997-11-21 2001-01-10 诺沃挪第克公司 蛋白酶变体及组合物
DE69837559T3 (de) 1997-12-24 2011-07-21 Genencor International, Inc., Calif. Verfahren zur Bestimmung der Waschleistung eines Enzyms.
CA2332334A1 (en) * 1998-06-23 1999-12-29 Novozymes A/S A polypeptide-polymer conjugate
US6376450B1 (en) 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
US6294514B1 (en) 1998-11-24 2001-09-25 The Procter & Gamble Company Process for preparing mono-long chain amine oxide surfactants with low nitrite, nitrosamine and low residual peroxide
CA2348893A1 (en) 1998-11-30 2000-06-08 The Procter & Gamble Company Process for preparing cross-bridged tetraaza macrocycles
ATE400648T1 (de) 2000-08-11 2008-07-15 Genencor Int Transformation von bacillus, transformanten und mutanten-bibliotheken
US6582914B1 (en) 2000-10-26 2003-06-24 Genencor International, Inc. Method for generating a library of oligonucleotides comprising a controlled distribution of mutations
CN1446911A (zh) * 2003-02-08 2003-10-08 复旦大学 一种人工基因生产嗜热菌蛋白酶的方法
ES2373658T3 (es) * 2003-06-18 2012-02-07 Bayer Pharma Aktiengesellschaft Nuevas entidades biológicas y el uso de las mismas.
WO2007044993A2 (en) * 2005-10-12 2007-04-19 Genencor International, Inc. Use and production of storage-stable neutral metalloprotease
CA2704311C (en) * 2007-11-01 2018-02-13 Danisco Us Inc. Production of thermolysin and variants thereof, and use in liquid detergents

Also Published As

Publication number Publication date
CN103305493A (zh) 2013-09-18
KR20100075993A (ko) 2010-07-05
CN103305493B (zh) 2018-07-10
RU2010122072A (ru) 2011-12-10
RU2014140895A (ru) 2016-04-27
EP2845900A1 (en) 2015-03-11
JP2011502506A (ja) 2011-01-27
EP2845900B1 (en) 2019-01-09
RU2536255C2 (ru) 2014-12-20
JP2013078334A (ja) 2013-05-02
CN101868538A (zh) 2010-10-20
CA2704311A1 (en) 2009-05-07
US20120009651A1 (en) 2012-01-12
US9976134B2 (en) 2018-05-22
US8569034B2 (en) 2013-10-29
US20160032266A1 (en) 2016-02-04
CA2704311C (en) 2018-02-13
BRPI0818144A2 (pt) 2014-10-14
RU2733541C2 (ru) 2020-10-05
JP2018068283A (ja) 2018-05-10
JP6139877B2 (ja) 2017-05-31
US20180251742A1 (en) 2018-09-06
RU2014140895A3 (enExample) 2018-06-04
WO2009058303A2 (en) 2009-05-07
WO2009058303A3 (en) 2010-01-07
MX2010004326A (es) 2010-05-20
JP6894342B2 (ja) 2021-06-30
JP2016052306A (ja) 2016-04-14
EP2205732A2 (en) 2010-07-14
CN101868538B (zh) 2013-07-10
US20140099698A1 (en) 2014-04-10

Similar Documents

Publication Publication Date Title
DK2845900T3 (en) PREPARATION OF THERMOLYSIN AND ITS VARIETIES AND USE IN LIQUID DETERGENTS
US20200231908A1 (en) Use and production of citrate-stable neutral metalloproteases
JP5674462B2 (ja) タンパク質の特性の改良方法
EP1934340B1 (en) Use and production of storage-stable neutral metalloprotease
EP3095859A1 (en) Compositions and methods comprising variant microbial proteases
US20110104786A1 (en) Use and production of neutral metalloproteases in a serine protease-free background