DK173084B1 - Quinuclidinderivater, fremgangsmåde til fremstilling heraf samt farmaceutisk præparat indeholdende disse - Google Patents

Quinuclidinderivater, fremgangsmåde til fremstilling heraf samt farmaceutisk præparat indeholdende disse Download PDF

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Publication number
DK173084B1
DK173084B1 DK198601966A DK196686A DK173084B1 DK 173084 B1 DK173084 B1 DK 173084B1 DK 198601966 A DK198601966 A DK 198601966A DK 196686 A DK196686 A DK 196686A DK 173084 B1 DK173084 B1 DK 173084B1
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Prior art keywords
group
af102b
pharmaceutical composition
af64a
rats
Prior art date
Application number
DK198601966A
Other languages
Danish (da)
English (en)
Other versions
DK196686A (da
DK196686D0 (da
Inventor
Abraham Fisher
Ishai Karton
Eliahu Heldman
Aharon Levy
Yona Grunfeld
Original Assignee
Israel State
Israel Inst For Biolog Res S O
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL75166A external-priority patent/IL75166A/xx
Application filed by Israel State, Israel Inst For Biolog Res S O filed Critical Israel State
Publication of DK196686D0 publication Critical patent/DK196686D0/da
Publication of DK196686A publication Critical patent/DK196686A/da
Application granted granted Critical
Publication of DK173084B1 publication Critical patent/DK173084B1/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
DK198601966A 1985-05-10 1986-04-29 Quinuclidinderivater, fremgangsmåde til fremstilling heraf samt farmaceutisk præparat indeholdende disse DK173084B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IL7516685 1985-05-10
IL75166A IL75166A (en) 1985-05-10 1985-05-10 2-substituted spiro(1,3-oxathiolane-5,3-quinuclidine)derivatives,their preparation and pharmaceutical compositions containing them and 3-hydroxy-3-mercaptomethylquinuclidine as intermidiate therefor
IL7756886 1986-01-10
IL7756886 1986-01-10

Publications (3)

Publication Number Publication Date
DK196686D0 DK196686D0 (da) 1986-04-29
DK196686A DK196686A (da) 1986-11-11
DK173084B1 true DK173084B1 (da) 1999-12-27

Family

ID=26321442

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198601966A DK173084B1 (da) 1985-05-10 1986-04-29 Quinuclidinderivater, fremgangsmåde til fremstilling heraf samt farmaceutisk præparat indeholdende disse

Country Status (9)

Country Link
US (1) US4855290A (de)
EP (1) EP0205247B1 (de)
JP (2) JPH0725767B2 (de)
AT (1) ATE83485T1 (de)
CA (1) CA1311479C (de)
DE (1) DE3687288T2 (de)
DK (1) DK173084B1 (de)
ES (1) ES8703461A1 (de)
NO (1) NO173785C (de)

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US5534520A (en) * 1990-04-10 1996-07-09 Fisher; Abraham Spiro compounds containing five-membered rings
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JP2983141B2 (ja) * 1993-10-06 1999-11-29 株式会社三和化学研究所 新規化合物及び該化合物を有効成分とする脳機能改善剤
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US6528529B1 (en) 1998-03-31 2003-03-04 Acadia Pharmaceuticals Inc. Compounds with activity on muscarinic receptors
JP4447685B2 (ja) * 1999-01-14 2010-04-07 第一三共株式会社 皮膚乾燥症治療剤
CA2360326C (en) * 1999-02-09 2011-04-05 Uab Research Foundation Use of 4-amino pyridine for treatment of peripheral neuropathies
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US6433168B1 (en) 1999-07-26 2002-08-13 Sumika Fine Chemicals Co., Ltd. Highly pure phenothiazine compound, production method thereof, production method of intermediate therefor, and hydrate and novel crystal as starting materials for the intermediate
KR100998804B1 (ko) * 2002-05-03 2010-12-06 이스라엘 인스티튜트 포 바이올로지컬 리서치 중추 및 말초 신경계 장애의 치료를 위한 방법 및 조성물,및 그에 유용한 신규 화합물
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US20050192321A1 (en) * 2003-09-15 2005-09-01 Meythaler Jay M. Treatment of neuropathy with rapid release aminopyridine
WO2006013914A1 (ja) * 2004-08-06 2006-02-09 Daiichi Pharmaceutical Co., Ltd. 口腔粘膜投与剤
KR20070090922A (ko) * 2004-12-15 2007-09-06 아스트라제네카 아베 니코틴성 아세틸콜린 수용체 리간드
EP2258358A3 (de) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenese mit Acetylcholinesterasehemmer
US7678363B2 (en) * 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
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JP5452165B2 (ja) * 2009-10-23 2014-03-26 第一ファインケミカル株式会社 キヌクリジン類の製造法
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Also Published As

Publication number Publication date
DK196686A (da) 1986-11-11
EP0205247A2 (de) 1986-12-17
ATE83485T1 (de) 1993-01-15
CA1311479C (en) 1992-12-15
EP0205247B1 (de) 1992-12-16
JPH0725767B2 (ja) 1995-03-22
US4855290A (en) 1989-08-08
DE3687288D1 (de) 1993-01-28
EP0205247A3 (en) 1988-02-03
ES8703461A1 (es) 1987-03-01
JPS61280497A (ja) 1986-12-11
NO861682L (no) 1986-11-11
DK196686D0 (da) 1986-04-29
NO173785C (no) 1994-02-02
ES554280A0 (es) 1987-03-01
NO173785B (no) 1993-10-25
JPH07223953A (ja) 1995-08-22
DE3687288T2 (de) 1993-04-15

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