DK171253B1 - Fremgangsmåde til fremstilling af 5-Q-[3,4-bipyri din]-6(1H)-on - Google Patents
Fremgangsmåde til fremstilling af 5-Q-[3,4-bipyri din]-6(1H)-on Download PDFInfo
- Publication number
- DK171253B1 DK171253B1 DK083981A DK83981A DK171253B1 DK 171253 B1 DK171253 B1 DK 171253B1 DK 083981 A DK083981 A DK 083981A DK 83981 A DK83981 A DK 83981A DK 171253 B1 DK171253 B1 DK 171253B1
- Authority
- DK
- Denmark
- Prior art keywords
- pyridinyl
- bipyridine
- dimethylamino
- propenylidene
- chloride hydrochloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/124,808 US4264609A (en) | 1980-02-26 | 1980-02-26 | N-[3-Dimethylamino-2-(4-pyridinyl)-2-propenylidene]-N-methylmethaniminium chloride hydrochloride, its use in preparing 5-(cyano or carbamyl)-[3,4'-bipyridin]-6(1H)-one and its use as a cardiotonic |
| US12480880 | 1980-02-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK83981A DK83981A (da) | 1981-08-27 |
| DK171253B1 true DK171253B1 (da) | 1996-08-12 |
Family
ID=22416880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK083981A DK171253B1 (da) | 1980-02-26 | 1981-02-25 | Fremgangsmåde til fremstilling af 5-Q-[3,4-bipyri din]-6(1H)-on |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US4264609A (de) |
| JP (1) | JPS56128758A (de) |
| KR (2) | KR840002067B1 (de) |
| AR (1) | AR230630A1 (de) |
| AT (2) | AT380237B (de) |
| AU (1) | AU541644B2 (de) |
| BE (1) | BE887663A (de) |
| CA (1) | CA1128523A (de) |
| CH (1) | CH647509A5 (de) |
| DE (1) | DE3107306A1 (de) |
| DK (1) | DK171253B1 (de) |
| ES (1) | ES499776A1 (de) |
| FI (1) | FI76787C (de) |
| FR (1) | FR2476646A1 (de) |
| GB (1) | GB2070600B (de) |
| HK (1) | HK71789A (de) |
| IE (1) | IE51696B1 (de) |
| IL (1) | IL62161A (de) |
| IT (1) | IT1210992B (de) |
| LU (1) | LU83169A1 (de) |
| MX (1) | MX6908E (de) |
| NL (1) | NL192109C (de) |
| NO (1) | NO156689C (de) |
| NZ (1) | NZ196282A (de) |
| PH (2) | PH19904A (de) |
| PT (1) | PT72573B (de) |
| SE (2) | SE437514B (de) |
| ZA (1) | ZA811124B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3685840D1 (de) | 1985-04-30 | 1992-08-06 | Dresden Arzneimittel | 3-cyan-pyridine, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4004012A (en) * | 1975-10-14 | 1977-01-18 | Sterling Drug Inc. | 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones |
| US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
-
1980
- 1980-02-26 US US06/124,808 patent/US4264609A/en not_active Expired - Lifetime
-
1981
- 1981-02-17 NZ NZ196282A patent/NZ196282A/xx unknown
- 1981-02-18 IL IL62161A patent/IL62161A/xx not_active IP Right Cessation
- 1981-02-20 AU AU67487/81A patent/AU541644B2/en not_active Expired
- 1981-02-20 ZA ZA00811124A patent/ZA811124B/xx unknown
- 1981-02-20 GB GB8105369A patent/GB2070600B/en not_active Expired
- 1981-02-24 IT IT8119952A patent/IT1210992B/it active
- 1981-02-24 PH PH25258A patent/PH19904A/en unknown
- 1981-02-24 CH CH1222/81A patent/CH647509A5/fr not_active IP Right Cessation
- 1981-02-24 SE SE8101205A patent/SE437514B/sv not_active IP Right Cessation
- 1981-02-24 FR FR8103609A patent/FR2476646A1/fr active Granted
- 1981-02-25 KR KR1019810000616A patent/KR840002067B1/ko active
- 1981-02-25 NL NL8100922A patent/NL192109C/nl not_active IP Right Cessation
- 1981-02-25 FI FI810582A patent/FI76787C/fi not_active IP Right Cessation
- 1981-02-25 BE BE1/10150A patent/BE887663A/fr not_active IP Right Cessation
- 1981-02-25 NO NO810639A patent/NO156689C/no unknown
- 1981-02-25 MX MX819321U patent/MX6908E/es unknown
- 1981-02-25 DK DK083981A patent/DK171253B1/da not_active IP Right Cessation
- 1981-02-25 IE IE397/81A patent/IE51696B1/en not_active IP Right Cessation
- 1981-02-25 CA CA371,690A patent/CA1128523A/en not_active Expired
- 1981-02-25 PT PT72573A patent/PT72573B/pt unknown
- 1981-02-25 ES ES499776A patent/ES499776A1/es not_active Expired
- 1981-02-25 AT AT0088581A patent/AT380237B/de not_active IP Right Cessation
- 1981-02-26 LU LU83169A patent/LU83169A1/fr unknown
- 1981-02-26 AR AR284447A patent/AR230630A1/es active
- 1981-02-26 JP JP2759981A patent/JPS56128758A/ja active Granted
- 1981-02-26 DE DE19813107306 patent/DE3107306A1/de active Granted
-
1982
- 1982-03-01 PH PH26927A patent/PH17145A/en unknown
-
1983
- 1983-08-26 AT AT0305683A patent/AT380236B/de not_active IP Right Cessation
-
1984
- 1984-05-21 SE SE8402727A patent/SE452764B/sv not_active IP Right Cessation
- 1984-08-22 KR KR1019840005058A patent/KR840002066B1/ko not_active IP Right Cessation
-
1989
- 1989-09-07 HK HK717/89A patent/HK71789A/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6513105B2 (ja) | トリアジン、ピリミジン及びピリジン誘導体の新規製造方法 | |
| US6670478B2 (en) | Process for preparing torsemide intermediate | |
| AU2001247592A1 (en) | Novel processes for preparing torsemide intermediate | |
| DK171253B1 (da) | Fremgangsmåde til fremstilling af 5-Q-[3,4-bipyri din]-6(1H)-on | |
| US4081451A (en) | Process for preparing 2-halogeno nicotinic acids | |
| KR100656636B1 (ko) | 6-메틸-2-(4-메틸-페닐)-이미다조[1,2-ａ]피리딘-3-(Ｎ,Ｎ-디메틸-아세트아미드) 및 중간체의 제조 방법 | |
| NO147838B (no) | Mellomprodukt til bruk ved fremstilling av det hypotensive middel 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimetoksykinazolin | |
| US4469871A (en) | Process for preparing 2-(lower-alkoxy)-1-(pyridinyl) ethenyl lower-alkyl ketones | |
| NO802137L (no) | Fremgangsmaate til fremstilling av 5-(pyridinyl)nikotinonitriler | |
| US4292431A (en) | Process for the production of hydroxymethylimidazoles | |
| RU2228929C2 (ru) | Способ получения 3s-3-амино-3-пиридилпропионовой кислоты и ее производных и промежуточное вещество | |
| EP3915984A1 (de) | Synthese von 3-brom-5-(2-ethylimidazo[1,2-alpha]pyridin-3-carbonyl)-2-hydroxybenzonitril | |
| US4310670A (en) | Low-temperature, aqueous conversion of 4-picoline derivative to 5-cyano-[3,4'-bipyridin]-6(1H)-one | |
| US4555577A (en) | 2,4-Dichloro-5-thiazolecarboxaldehyde and a process for its preparation | |
| KR890001241B1 (ko) | 4-아세틸 이소퀴놀리논 화합물의 제조방법 | |
| KR880002354B1 (ko) | 1,2-디하이드로-6-(저급알킬)-2-옥소-5-(피리디닐)니코티노니트릴류 및 니코틴아미드류의 제조방법 | |
| CN111892606B (zh) | 1,4,7-三氮环壬烷-1,4-酮及1,4,7-三氮环壬烷-1,4-硫酮合成方法 | |
| SU1299509A3 (ru) | Способ получени гетероциклических производных или их фармацевтически приемлемых аддитивных солей кислоты | |
| NO882085L (no) | Cyklobutenmellomprodukt. | |
| US4831139A (en) | Process for the preparation of 2-substituted 5-nitroso-4,6-diaminopyrimidines | |
| EP1741429A2 (de) | Verfahren zur Herstellung von Torsemide | |
| GB1564503A (en) | Alkoxypyridyl amines | |
| JPS62145B2 (de) | ||
| PL182168B1 (pl) | Sposób otrzymywania 5-cyjano-[3,4’-bipirydyn]-6(1H)-onu | |
| JPS6156162A (ja) | Ｎ―フェニル（ピリジル）―スルホニルジアミドの製造法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |