SE8101205L - Nya iminiumsalter och forfarande for framstellning av 5-(cyano eller karbamyl)-(3,4-bipyridin)-6(1h)-on - Google Patents
Nya iminiumsalter och forfarande for framstellning av 5-(cyano eller karbamyl)-(3,4-bipyridin)-6(1h)-onInfo
- Publication number
- SE8101205L SE8101205L SE8101205A SE8101205A SE8101205L SE 8101205 L SE8101205 L SE 8101205L SE 8101205 A SE8101205 A SE 8101205A SE 8101205 A SE8101205 A SE 8101205A SE 8101205 L SE8101205 L SE 8101205L
- Authority
- SE
- Sweden
- Prior art keywords
- carbamyl
- cyano
- bipyridine
- procedures
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/124,808 US4264609A (en) | 1980-02-26 | 1980-02-26 | N-[3-Dimethylamino-2-(4-pyridinyl)-2-propenylidene]-N-methylmethaniminium chloride hydrochloride, its use in preparing 5-(cyano or carbamyl)-[3,4'-bipyridin]-6(1H)-one and its use as a cardiotonic |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8101205L true SE8101205L (sv) | 1981-08-27 |
SE437514B SE437514B (sv) | 1985-03-04 |
Family
ID=22416880
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8101205A SE437514B (sv) | 1980-02-26 | 1981-02-24 | N-/3-dimetylamino-2-(4-pyridinyl)-2-propenyliden/-n-metylmetaniminiumsalt, sett att framstella detta och kardioton komposition for okning av hjertkontraktiliteten |
SE8402727A SE452764B (sv) | 1980-02-26 | 1984-05-21 | Forfarande for framstellning av 5-(cyano eller karbamyl)-(3,4-bipyridin)-6(1h)-on |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8402727A SE452764B (sv) | 1980-02-26 | 1984-05-21 | Forfarande for framstellning av 5-(cyano eller karbamyl)-(3,4-bipyridin)-6(1h)-on |
Country Status (28)
Country | Link |
---|---|
US (1) | US4264609A (sv) |
JP (1) | JPS56128758A (sv) |
KR (2) | KR840002067B1 (sv) |
AR (1) | AR230630A1 (sv) |
AT (2) | AT380237B (sv) |
AU (1) | AU541644B2 (sv) |
BE (1) | BE887663A (sv) |
CA (1) | CA1128523A (sv) |
CH (1) | CH647509A5 (sv) |
DE (1) | DE3107306A1 (sv) |
DK (1) | DK171253B1 (sv) |
ES (1) | ES499776A1 (sv) |
FI (1) | FI76787C (sv) |
FR (1) | FR2476646A1 (sv) |
GB (1) | GB2070600B (sv) |
HK (1) | HK71789A (sv) |
IE (1) | IE51696B1 (sv) |
IL (1) | IL62161A (sv) |
IT (1) | IT1210992B (sv) |
LU (1) | LU83169A1 (sv) |
MX (1) | MX6908E (sv) |
NL (1) | NL192109C (sv) |
NO (1) | NO156689C (sv) |
NZ (1) | NZ196282A (sv) |
PH (2) | PH19904A (sv) |
PT (1) | PT72573B (sv) |
SE (2) | SE437514B (sv) |
ZA (1) | ZA811124B (sv) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3685840D1 (de) | 1985-04-30 | 1992-08-06 | Dresden Arzneimittel | 3-cyan-pyridine, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4004012A (en) * | 1975-10-14 | 1977-01-18 | Sterling Drug Inc. | 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones |
US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
-
1980
- 1980-02-26 US US06/124,808 patent/US4264609A/en not_active Expired - Lifetime
-
1981
- 1981-02-17 NZ NZ196282A patent/NZ196282A/xx unknown
- 1981-02-18 IL IL62161A patent/IL62161A/xx not_active IP Right Cessation
- 1981-02-20 GB GB8105369A patent/GB2070600B/en not_active Expired
- 1981-02-20 AU AU67487/81A patent/AU541644B2/en not_active Expired
- 1981-02-20 ZA ZA00811124A patent/ZA811124B/xx unknown
- 1981-02-24 PH PH25258A patent/PH19904A/en unknown
- 1981-02-24 SE SE8101205A patent/SE437514B/sv not_active IP Right Cessation
- 1981-02-24 CH CH1222/81A patent/CH647509A5/fr not_active IP Right Cessation
- 1981-02-24 FR FR8103609A patent/FR2476646A1/fr active Granted
- 1981-02-24 IT IT8119952A patent/IT1210992B/it active
- 1981-02-25 NO NO810639A patent/NO156689C/no unknown
- 1981-02-25 FI FI810582A patent/FI76787C/sv not_active IP Right Cessation
- 1981-02-25 DK DK083981A patent/DK171253B1/da not_active IP Right Cessation
- 1981-02-25 CA CA371,690A patent/CA1128523A/en not_active Expired
- 1981-02-25 MX MX819321U patent/MX6908E/es unknown
- 1981-02-25 ES ES499776A patent/ES499776A1/es not_active Expired
- 1981-02-25 PT PT72573A patent/PT72573B/pt unknown
- 1981-02-25 IE IE397/81A patent/IE51696B1/en not_active IP Right Cessation
- 1981-02-25 AT AT0088581A patent/AT380237B/de not_active IP Right Cessation
- 1981-02-25 NL NL8100922A patent/NL192109C/nl not_active IP Right Cessation
- 1981-02-25 BE BE1/10150A patent/BE887663A/fr not_active IP Right Cessation
- 1981-02-25 KR KR1019810000616A patent/KR840002067B1/ko active
- 1981-02-26 LU LU83169A patent/LU83169A1/fr unknown
- 1981-02-26 AR AR284447A patent/AR230630A1/es active
- 1981-02-26 JP JP2759981A patent/JPS56128758A/ja active Granted
- 1981-02-26 DE DE19813107306 patent/DE3107306A1/de active Granted
-
1982
- 1982-03-01 PH PH26927A patent/PH17145A/en unknown
-
1983
- 1983-08-26 AT AT0305683A patent/AT380236B/de not_active IP Right Cessation
-
1984
- 1984-05-21 SE SE8402727A patent/SE452764B/sv not_active IP Right Cessation
- 1984-08-22 KR KR1019840005058A patent/KR840002066B1/ko not_active IP Right Cessation
-
1989
- 1989-09-07 HK HK717/89A patent/HK71789A/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2300151T3 (es) | Derivados de cianofenilo. | |
ES2325461T3 (es) | Inhibidores de pirrolotriazina cinasa. | |
ES2342240T3 (es) | Derivados de isoquinolina con actividad que inhibe la angiogenia. | |
JP7305196B2 (ja) | ハロアリルアミン類のssao/vap-1阻害剤とその用途 | |
ES2241781T3 (es) | Derivados de piridina inhibidores de la angiogenesis y/o del receptor tirosina quinasa de vegf. | |
ES2324768T3 (es) | 2,6-diamino-3,5-diciano-4-arilpiridinas sustituidas y su uso como ligandos selectivos de receptores de adenosina. | |
US7879839B2 (en) | Potassium channel inhibitors | |
JP7219902B2 (ja) | ブルトン型チロシンキナーゼ阻害剤 | |
SE8102022L (sv) | Intermediat i form av 2(ih)-pyridinoner samt forfarande for framstellning derav | |
EP0303697A1 (en) | Derivatives of physiologically active substance k-252 | |
IL155447A (en) | Nitrogenic aromatic circular compounds | |
JP2008517956A (ja) | 二重の抗血小板性/抗凝固性ピリドキシン類似体 | |
JPH11269146A (ja) | 分化誘導剤 | |
SE8501169D0 (sv) | Diaminopyridin-intermedierer | |
US10214554B2 (en) | Process for making chloro-substituted nucleoside phosphoramidate compounds | |
US4060601A (en) | Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines | |
US20170298070A1 (en) | Novel chiral synthesis of n-acyl-(3-substituted)-(8-substituted)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazines | |
KR920016421A (ko) | 피리딘 화합물 | |
SE8101205L (sv) | Nya iminiumsalter och forfarande for framstellning av 5-(cyano eller karbamyl)-(3,4-bipyridin)-6(1h)-on | |
ES8706151A1 (es) | Un procedimiento para preparar un derivado de 1,6-naftiri- din-2(1h)-ona | |
JP2021530455A (ja) | 三環式化合物 | |
NO832784L (no) | 5-(lavere-alkyl)-1,6-nafthyridin-2(1h)-on-forbindelser og fremgangsmaate for deres fremstilling | |
US4144343A (en) | Heterocycle substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines | |
JP4464560B2 (ja) | 置換イソインドロンおよび医薬におけるサイクリックgmp調節剤としてのそれらの使用 | |
CN109516984A (zh) | 一种2-巯基-5-氰基嘧啶类衍生物及其制备方法和应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAL | Patent in force |
Ref document number: 8101205-6 Format of ref document f/p: F |
|
NUG | Patent has lapsed |
Ref document number: 8101205-6 Format of ref document f/p: F |