PH19904A - Novel iminium salts,process for preparing 5-(cyano-or carbamyl)-3,4-bipyridine-6(1h)-one and compositions containing the same - Google Patents

Novel iminium salts,process for preparing 5-(cyano-or carbamyl)-3,4-bipyridine-6(1h)-one and compositions containing the same

Info

Publication number
PH19904A
PH19904A PH25258A PH25258A PH19904A PH 19904 A PH19904 A PH 19904A PH 25258 A PH25258 A PH 25258A PH 25258 A PH25258 A PH 25258A PH 19904 A PH19904 A PH 19904A
Authority
PH
Philippines
Prior art keywords
carbamyl
bipyridine
cyano
preparing
same
Prior art date
Application number
PH25258A
Other languages
English (en)
Inventor
Karl Olaf Gelotte
Chester Joseph Opalka
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of PH19904A publication Critical patent/PH19904A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH25258A 1980-02-26 1981-02-24 Novel iminium salts,process for preparing 5-(cyano-or carbamyl)-3,4-bipyridine-6(1h)-one and compositions containing the same PH19904A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/124,808 US4264609A (en) 1980-02-26 1980-02-26 N-[3-Dimethylamino-2-(4-pyridinyl)-2-propenylidene]-N-methylmethaniminium chloride hydrochloride, its use in preparing 5-(cyano or carbamyl)-[3,4'-bipyridin]-6(1H)-one and its use as a cardiotonic

Publications (1)

Publication Number Publication Date
PH19904A true PH19904A (en) 1986-08-13

Family

ID=22416880

Family Applications (2)

Application Number Title Priority Date Filing Date
PH25258A PH19904A (en) 1980-02-26 1981-02-24 Novel iminium salts,process for preparing 5-(cyano-or carbamyl)-3,4-bipyridine-6(1h)-one and compositions containing the same
PH26927A PH17145A (en) 1980-02-26 1982-03-01 Process for preparing 5-(cyano or carbamyl)-(3,4-bipyridin)-6(1h)-one

Family Applications After (1)

Application Number Title Priority Date Filing Date
PH26927A PH17145A (en) 1980-02-26 1982-03-01 Process for preparing 5-(cyano or carbamyl)-(3,4-bipyridin)-6(1h)-one

Country Status (28)

Country Link
US (1) US4264609A (de)
JP (1) JPS56128758A (de)
KR (2) KR840002067B1 (de)
AR (1) AR230630A1 (de)
AT (2) AT380237B (de)
AU (1) AU541644B2 (de)
BE (1) BE887663A (de)
CA (1) CA1128523A (de)
CH (1) CH647509A5 (de)
DE (1) DE3107306A1 (de)
DK (1) DK171253B1 (de)
ES (1) ES499776A1 (de)
FI (1) FI76787C (de)
FR (1) FR2476646A1 (de)
GB (1) GB2070600B (de)
HK (1) HK71789A (de)
IE (1) IE51696B1 (de)
IL (1) IL62161A (de)
IT (1) IT1210992B (de)
LU (1) LU83169A1 (de)
MX (1) MX6908E (de)
NL (1) NL192109C (de)
NO (1) NO156689C (de)
NZ (1) NZ196282A (de)
PH (2) PH19904A (de)
PT (1) PT72573B (de)
SE (2) SE437514B (de)
ZA (1) ZA811124B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200024B1 (de) 1985-04-30 1992-07-01 ARZNEIMITTELWERK DRESDEN GmbH 3-Cyan-pyridine, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4004012A (en) * 1975-10-14 1977-01-18 Sterling Drug Inc. 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones
US4072746A (en) * 1975-10-14 1978-02-07 Sterling Drug Inc. 3-Amino-5-(pyridinyl)-2(1H)-pyridinones

Also Published As

Publication number Publication date
AU6748781A (en) 1981-09-03
NZ196282A (en) 1983-12-16
IT8119952A0 (it) 1981-02-24
DK171253B1 (da) 1996-08-12
KR830005143A (ko) 1983-08-03
HK71789A (en) 1989-09-14
IE51696B1 (en) 1987-02-18
SE8402727D0 (sv) 1984-05-21
FI76787C (fi) 1988-12-12
IT1210992B (it) 1989-09-29
US4264609A (en) 1981-04-28
CH647509A5 (fr) 1985-01-31
CA1128523A (en) 1982-07-27
LU83169A1 (fr) 1981-09-11
PT72573B (en) 1982-02-12
DE3107306C2 (de) 1990-11-29
NO810639L (no) 1981-08-27
NO156689C (no) 1987-11-04
AR230630A1 (es) 1984-05-31
FI810582L (fi) 1981-08-27
NO156689B (no) 1987-07-27
SE452764B (sv) 1987-12-14
DK83981A (da) 1981-08-27
DE3107306A1 (de) 1981-12-17
BE887663A (fr) 1981-08-25
AT380236B (de) 1986-04-25
MX6908E (es) 1986-11-07
FR2476646B1 (de) 1984-08-17
NL192109B (nl) 1996-10-01
FR2476646A1 (fr) 1981-08-28
ES499776A1 (es) 1984-06-16
IE810397L (en) 1981-08-26
IL62161A0 (en) 1981-03-31
AT380237B (de) 1986-04-25
PH17145A (en) 1984-06-04
ATA305683A (de) 1985-09-15
GB2070600B (en) 1984-07-11
SE437514B (sv) 1985-03-04
PT72573A (pt) 1981-03-01
ATA88581A (de) 1985-09-15
NL8100922A (nl) 1981-09-16
SE8101205L (sv) 1981-08-27
ZA811124B (en) 1982-03-31
KR840002066B1 (ko) 1984-11-09
SE8402727L (sv) 1984-05-21
IL62161A (en) 1984-06-29
KR840002067B1 (ko) 1984-11-09
JPH0141626B2 (de) 1989-09-06
AU541644B2 (en) 1985-01-17
GB2070600A (en) 1981-09-09
NL192109C (nl) 1997-02-04
JPS56128758A (en) 1981-10-08
FI76787B (fi) 1988-08-31

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