DK169538B1 - Aminoalkoholer og syreadditionssalte deraf, fremgangsmåde til deres fremstilling og lægemidler med indhold af sådanne - Google Patents

Aminoalkoholer og syreadditionssalte deraf, fremgangsmåde til deres fremstilling og lægemidler med indhold af sådanne Download PDF

Info

Publication number
DK169538B1
DK169538B1 DK040687A DK40687A DK169538B1 DK 169538 B1 DK169538 B1 DK 169538B1 DK 040687 A DK040687 A DK 040687A DK 40687 A DK40687 A DK 40687A DK 169538 B1 DK169538 B1 DK 169538B1
Authority
DK
Denmark
Prior art keywords
formula
compounds
alkyl
compound
methyl
Prior art date
Application number
DK040687A
Other languages
Danish (da)
English (en)
Other versions
DK40687D0 (da
DK40687A (da
Inventor
Gilbert Aubard
Jacques Bure
Pierre Alain Calvet
Claude Gouret
Genevieve Agnes Grouhel
Jean-Louis Junien
Original Assignee
Jouveinal Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jouveinal Sa filed Critical Jouveinal Sa
Publication of DK40687D0 publication Critical patent/DK40687D0/da
Publication of DK40687A publication Critical patent/DK40687A/da
Application granted granted Critical
Publication of DK169538B1 publication Critical patent/DK169538B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Heat Treatment Of Sheet Steel (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK040687A 1986-01-30 1987-01-26 Aminoalkoholer og syreadditionssalte deraf, fremgangsmåde til deres fremstilling og lægemidler med indhold af sådanne DK169538B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8601295A FR2593499B1 (fr) 1986-01-30 1986-01-30 Aminoalcools, leur procede de preparation et leurs applications, notamment en therapeutique
FR8601295 1986-01-30

Publications (3)

Publication Number Publication Date
DK40687D0 DK40687D0 (da) 1987-01-26
DK40687A DK40687A (da) 1987-07-31
DK169538B1 true DK169538B1 (da) 1994-11-28

Family

ID=9331637

Family Applications (1)

Application Number Title Priority Date Filing Date
DK040687A DK169538B1 (da) 1986-01-30 1987-01-26 Aminoalkoholer og syreadditionssalte deraf, fremgangsmåde til deres fremstilling og lægemidler med indhold af sådanne

Country Status (17)

Country Link
US (1) US4994617A (sv)
EP (1) EP0237366B1 (sv)
JP (1) JPH089580B2 (sv)
KR (1) KR950006891B1 (sv)
AT (1) ATE42540T1 (sv)
AU (1) AU590664B2 (sv)
BR (1) BR1100977A (sv)
CA (1) CA1294961C (sv)
DE (1) DE3760117D1 (sv)
DK (1) DK169538B1 (sv)
ES (1) ES2008109B3 (sv)
FI (1) FI87068C (sv)
FR (1) FR2593499B1 (sv)
GR (1) GR3000026T3 (sv)
IE (1) IE59448B1 (sv)
NZ (1) NZ218988A (sv)
PT (1) PT84223B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4939133A (en) * 1985-10-01 1990-07-03 Warner-Lambert Company N-substituted-2-hydroxy-α-oxo-benzeneacetamides and pharmaceutical compositions having activity as modulators of the arachidonic acid cascade
US5482947A (en) * 1990-11-19 1996-01-09 Talley; John J. Retroviral protease inhibitors
FR2690916B1 (fr) * 1992-05-05 1994-06-17 Jouveinal Inst Rech Nouveaux enantiomeres derives du (s)-amino-2-(dichloro-3,4-benzyl)-2-propanol-1.
FR2690917B1 (fr) * 1992-05-05 1994-06-17 Jouveinal Inst Rech Aminoesters, leur procede de preparation et leur application en therapeutique.
US5472970A (en) * 1992-05-05 1995-12-05 Institut De Recherche Jouveinal S.A. Allylaminoesters and their application in therapeutics
US5367094A (en) * 1993-06-04 1994-11-22 Yukong, Ltd. Convenient process for the preparation of chiral or racemic phenylalaninols and their N-blocked derivatives
FR2761686B1 (fr) * 1997-04-07 1999-05-14 Sipsy Sa Nouveau procede de preparation du (+/-)3-(3,4- dichlorophenyl)-2-dimethylamino-2-methyl-propan-1-ol ou cericlamine (inn)
US7216702B2 (en) * 2003-02-28 2007-05-15 Yates Petroleum Corporation Methods of evaluating undersaturated coalbed methane reservoirs
EP1691811B1 (en) 2003-12-11 2014-07-23 Sunovion Pharmaceuticals Inc. Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
US7467260B2 (en) * 2004-10-08 2008-12-16 International Business Machines Corporation Method and apparatus to purge remote node cache lines to support hot node replace in a computing system
CZ2009385A3 (cs) * 2009-06-16 2010-07-28 Zentiva, K. S. Zpusob výroby (S)-4-methylamino-3-(3,4-dichlorfenyl)butan-1-olu

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3132179A (en) * 1959-08-27 1964-05-05 Sterling Drug Inc Ethers of alpha-hydroxymethyl-beta-monocarbocyclic aryl ethyl amines and their preparation
US3193581A (en) * 1961-03-01 1965-07-06 Yamanouchi Pharma Co Ltd Process of preparing 1-phenyl-2-aminopropane
US3573304A (en) * 1968-12-03 1971-03-30 Delalande Sa 1-dimethylamino - 3 - methyl-2(pyridyl or pyridazinyl) pentane and the corresponding non-toxic acid addition salts thereof
US3706764A (en) * 1969-04-16 1972-12-19 Yoshitomi Pharmaceutical Phenethylaminomethyl-chromanones and- thiochromanones
US3896166A (en) * 1970-05-06 1975-07-22 Hoffmann La Roche Formyl-substituted tyrosine
NL7112938A (sv) * 1970-09-30 1972-04-05
ES399820A1 (es) * 1971-02-17 1975-07-01 Sandoz Ag Procedimiento para la obtencion de derivados de amino pro- panol.
GB1346401A (en) * 1971-05-12 1974-02-13 Lepetit Spa Cardioactive arylaminobutanols
US4058642A (en) * 1973-10-11 1977-11-15 Boehringer Ingelheim Gmbh 2-Amino-3-(3'-hydroxy-phenyl)-propanols and salts thereof
GB1434826A (en) * 1973-11-14 1976-05-05 Gallardo Antonio Sa Esters and carbamates of aminoalkanols
US4536601A (en) * 1982-09-28 1985-08-20 Dainippon Pharmaceutical Co., Ltd. Optically active N-substituted phenylalaninols and use thereof

Also Published As

Publication number Publication date
PT84223B (pt) 1989-05-31
GR3000026T3 (en) 1990-01-19
JPS62190150A (ja) 1987-08-20
KR870007101A (ko) 1987-08-14
JPH089580B2 (ja) 1996-01-31
DE3760117D1 (en) 1989-06-01
IE59448B1 (en) 1994-02-23
FI87068C (sv) 1992-11-25
AU6795987A (en) 1987-08-06
US4994617A (en) 1991-02-19
AU590664B2 (en) 1989-11-09
DK40687D0 (da) 1987-01-26
KR950006891B1 (ko) 1995-06-26
ATE42540T1 (de) 1989-05-15
EP0237366B1 (fr) 1989-04-26
CA1294961C (en) 1992-01-28
FI870418A (fi) 1987-07-31
FI87068B (fi) 1992-08-14
FR2593499A1 (fr) 1987-07-31
PT84223A (fr) 1987-02-01
ES2008109B3 (es) 1989-07-16
EP0237366A1 (fr) 1987-09-16
FI870418A0 (fi) 1987-01-30
FR2593499B1 (fr) 1988-08-12
NZ218988A (en) 1990-02-26
DK40687A (da) 1987-07-31
IE870062L (en) 1987-07-30
BR1100977A (pt) 1999-10-13

Similar Documents

Publication Publication Date Title
FI95698B (sv) Analogiförfarande för framställning av terapeutiskt användbara 1-indolylalkyl-4-(substituerat pyridinyl)piperaziner
RU2351588C2 (ru) Производные n-фенил(пиперидин-2-ил)метил-бензамида и их применение в терапии
DK169538B1 (da) Aminoalkoholer og syreadditionssalte deraf, fremgangsmåde til deres fremstilling og lægemidler med indhold af sådanne
KR20120104525A (ko) 라이신 특이적 디메틸라아제-1 억제제 및 이의 용도
JP2000504677A (ja) ５ｈｔ７レセプター・アンタゴニスト用のスルホンアミド誘導体
IE51918B1 (en) Bicyclic compounds their production and use
DK162629B (da) 2-substituerede 1-aralkyl-imidazoler og farmaceutiske midler der indeholder disse, anvendelse heraf til fremstilling af farmaceutiske midler samt fremgangsmaade til fremstilling heraf
JPH0739387B2 (ja) 新規１−ベンジル−アミノアルキル−ピロリジノン化合物及びその製造方法
ITMI951020A1 (it) Derivati di diarildiammine
KR20010021957A (ko) 피페라진 유도체
DK162985B (da) Pyridazinderivater, som i 3-stillingen er substitueret med amino, og som indvirker paa centralnervesystemet, fremgangsmaade til fremstilling heraf og laegemidler med indhold heraf
EP0299349A2 (en) N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds, a process for their preparation and their use as medicaments
NZ546186A (en) Indanyl-piperazine compounds, a process for their preparation and pharmaceutical compositions containing them
DK163181B (da) Analogifremgangsmaade til fremstilling af n,n'-di(arylalkylen)alkylendiaminer eller farmaceutisk acceptable salte deraf
CA3213289A1 (en) Phenalkylamines and methods of making and using the same
DK157864B (da) Hidtil ukendte 1-piperazincarboxamidderivater substitueret paa det basiske nitrogenatom samt farmaceutiske praeparater og sammensaetninger indeholdende disse
DE69411589T2 (de) Indol, indolin und chinolin derivate mit einer 5ht1d antagonistischen wirkung
DE3688397T2 (de) 3-(2-aminoethyl)indol und -indolinderivate, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen.
DE68909757T2 (de) Indanderivate, Verfahren zu ihrer Herstellung und erhaltene Zwischenprodukte, ihre Verwendung als Arzneimittel und diese enthaltende pharmazeutische Zusammensetzungen.
CZ325196A3 (en) Derivatives of hydroximic acid, pharmaceutical compositions containing thereof, process of their preparation and intermediates used in the preparation process
KR910003711B1 (ko) 2-(n-피롤리디노)-3-이소부톡시-n-치환된 페닐-n-벤질-프로필아민의 제조방법
JPH09504014A (ja) カルシウムチャネル拮抗薬としてのアミン誘導体類
DK167063B1 (da) Hidtil ukendte 2-(2,3-dihydro-2-oxo-3-benzofuranyl)-eddikesyrederivater, fremgangsmaade til deres fremstilling og farmaceutiske midler indeholdende dem
GB2162843A (en) Piperazine derivatives
SU833157A3 (ru) Способ получени производных циклододекана или их оптическиАКТиВНыХ изОМЕРОВ B СВОбОдНОМ ВидЕ,B ВидЕ СОли или чЕТВЕРТич-НыХ АММОНиЕВыХ пРОизВОдНыХ

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

Country of ref document: DK