DE3760117D1 - Amino alcohols, process for their preparation and their applications, in particular for therepeutical use - Google Patents

Amino alcohols, process for their preparation and their applications, in particular for therepeutical use

Info

Publication number
DE3760117D1
DE3760117D1 DE8787400116T DE3760117T DE3760117D1 DE 3760117 D1 DE3760117 D1 DE 3760117D1 DE 8787400116 T DE8787400116 T DE 8787400116T DE 3760117 T DE3760117 T DE 3760117T DE 3760117 D1 DE3760117 D1 DE 3760117D1
Authority
DE
Germany
Prior art keywords
alkyl
compound
nitrogen
cycle
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8787400116T
Other languages
English (en)
Inventor
Gilbert Aubard
Jacques Bure
Alain Pierre Calvet
Claude Gouret
Agnes Genevieve Grouhel
Jean-Louis Junien
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jouveinal SA
Original Assignee
Jouveinal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jouveinal SA filed Critical Jouveinal SA
Application granted granted Critical
Publication of DE3760117D1 publication Critical patent/DE3760117D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Heat Treatment Of Sheet Steel (AREA)
DE8787400116T 1986-01-30 1987-01-19 Amino alcohols, process for their preparation and their applications, in particular for therepeutical use Expired DE3760117D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8601295A FR2593499B1 (fr) 1986-01-30 1986-01-30 Aminoalcools, leur procede de preparation et leurs applications, notamment en therapeutique

Publications (1)

Publication Number Publication Date
DE3760117D1 true DE3760117D1 (en) 1989-06-01

Family

ID=9331637

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787400116T Expired DE3760117D1 (en) 1986-01-30 1987-01-19 Amino alcohols, process for their preparation and their applications, in particular for therepeutical use

Country Status (17)

Country Link
US (1) US4994617A (de)
EP (1) EP0237366B1 (de)
JP (1) JPH089580B2 (de)
KR (1) KR950006891B1 (de)
AT (1) ATE42540T1 (de)
AU (1) AU590664B2 (de)
BR (1) BR1100977A (de)
CA (1) CA1294961C (de)
DE (1) DE3760117D1 (de)
DK (1) DK169538B1 (de)
ES (1) ES2008109B3 (de)
FI (1) FI87068C (de)
FR (1) FR2593499B1 (de)
GR (1) GR3000026T3 (de)
IE (1) IE59448B1 (de)
NZ (1) NZ218988A (de)
PT (1) PT84223B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4939133A (en) * 1985-10-01 1990-07-03 Warner-Lambert Company N-substituted-2-hydroxy-α-oxo-benzeneacetamides and pharmaceutical compositions having activity as modulators of the arachidonic acid cascade
US5482947A (en) * 1990-11-19 1996-01-09 Talley; John J. Retroviral protease inhibitors
FR2690917B1 (fr) * 1992-05-05 1994-06-17 Jouveinal Inst Rech Aminoesters, leur procede de preparation et leur application en therapeutique.
US5472970A (en) * 1992-05-05 1995-12-05 Institut De Recherche Jouveinal S.A. Allylaminoesters and their application in therapeutics
FR2690916B1 (fr) * 1992-05-05 1994-06-17 Jouveinal Inst Rech Nouveaux enantiomeres derives du (s)-amino-2-(dichloro-3,4-benzyl)-2-propanol-1.
US5367094A (en) * 1993-06-04 1994-11-22 Yukong, Ltd. Convenient process for the preparation of chiral or racemic phenylalaninols and their N-blocked derivatives
FR2761686B1 (fr) * 1997-04-07 1999-05-14 Sipsy Sa Nouveau procede de preparation du (+/-)3-(3,4- dichlorophenyl)-2-dimethylamino-2-methyl-propan-1-ol ou cericlamine (inn)
US7216702B2 (en) * 2003-02-28 2007-05-15 Yates Petroleum Corporation Methods of evaluating undersaturated coalbed methane reservoirs
US20050176680A1 (en) 2003-12-11 2005-08-11 Sepracor, Inc. Combination of sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
US7467260B2 (en) * 2004-10-08 2008-12-16 International Business Machines Corporation Method and apparatus to purge remote node cache lines to support hot node replace in a computing system
CZ2009385A3 (cs) * 2009-06-16 2010-07-28 Zentiva, K. S. Zpusob výroby (S)-4-methylamino-3-(3,4-dichlorfenyl)butan-1-olu

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3132179A (en) * 1959-08-27 1964-05-05 Sterling Drug Inc Ethers of alpha-hydroxymethyl-beta-monocarbocyclic aryl ethyl amines and their preparation
US3193581A (en) * 1961-03-01 1965-07-06 Yamanouchi Pharma Co Ltd Process of preparing 1-phenyl-2-aminopropane
US3573304A (en) * 1968-12-03 1971-03-30 Delalande Sa 1-dimethylamino - 3 - methyl-2(pyridyl or pyridazinyl) pentane and the corresponding non-toxic acid addition salts thereof
US3706764A (en) * 1969-04-16 1972-12-19 Yoshitomi Pharmaceutical Phenethylaminomethyl-chromanones and- thiochromanones
US3896166A (en) * 1970-05-06 1975-07-22 Hoffmann La Roche Formyl-substituted tyrosine
NL7112938A (de) * 1970-09-30 1972-04-05
ES399820A1 (es) * 1971-02-17 1975-07-01 Sandoz Ag Procedimiento para la obtencion de derivados de amino pro- panol.
GB1346401A (en) * 1971-05-12 1974-02-13 Lepetit Spa Cardioactive arylaminobutanols
US4058642A (en) * 1973-10-11 1977-11-15 Boehringer Ingelheim Gmbh 2-Amino-3-(3'-hydroxy-phenyl)-propanols and salts thereof
GB1434826A (en) * 1973-11-14 1976-05-05 Gallardo Antonio Sa Esters and carbamates of aminoalkanols
US4536601A (en) * 1982-09-28 1985-08-20 Dainippon Pharmaceutical Co., Ltd. Optically active N-substituted phenylalaninols and use thereof

Also Published As

Publication number Publication date
FI870418A0 (fi) 1987-01-30
GR3000026T3 (en) 1990-01-19
JPH089580B2 (ja) 1996-01-31
KR870007101A (ko) 1987-08-14
US4994617A (en) 1991-02-19
IE59448B1 (en) 1994-02-23
EP0237366A1 (de) 1987-09-16
PT84223A (fr) 1987-02-01
BR1100977A (pt) 1999-10-13
DK40687A (da) 1987-07-31
NZ218988A (en) 1990-02-26
ATE42540T1 (de) 1989-05-15
AU6795987A (en) 1987-08-06
ES2008109B3 (es) 1989-07-16
FI870418A (fi) 1987-07-31
FI87068B (fi) 1992-08-14
FI87068C (fi) 1992-11-25
DK169538B1 (da) 1994-11-28
FR2593499B1 (fr) 1988-08-12
EP0237366B1 (de) 1989-04-26
CA1294961C (en) 1992-01-28
IE870062L (en) 1987-07-30
FR2593499A1 (fr) 1987-07-31
AU590664B2 (en) 1989-11-09
DK40687D0 (da) 1987-01-26
KR950006891B1 (ko) 1995-06-26
JPS62190150A (ja) 1987-08-20
PT84223B (pt) 1989-05-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee