DK40687A - Aminoalkoholer, fremgangsmaade til deres fremstilling og laegemidler med indhold af saadanne - Google Patents
Aminoalkoholer, fremgangsmaade til deres fremstilling og laegemidler med indhold af saadanneInfo
- Publication number
- DK40687A DK40687A DK040687A DK40687A DK40687A DK 40687 A DK40687 A DK 40687A DK 040687 A DK040687 A DK 040687A DK 40687 A DK40687 A DK 40687A DK 40687 A DK40687 A DK 40687A
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- compound
- nitrogen
- cycle
- carbon atoms
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000001298 alcohols Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 14
- 150000001875 compounds Chemical class 0.000 abstract 14
- 229910052757 nitrogen Inorganic materials 0.000 abstract 9
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 6
- 239000002253 acid Substances 0.000 abstract 6
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 6
- 125000003342 alkenyl group Chemical group 0.000 abstract 5
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 5
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 5
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 4
- 239000005864 Sulphur Substances 0.000 abstract 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 4
- 125000001589 carboacyl group Chemical group 0.000 abstract 4
- 125000006254 cycloalkyl carbonyl group Chemical group 0.000 abstract 4
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 4
- 125000000623 heterocyclic group Chemical group 0.000 abstract 4
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 4
- 229910052760 oxygen Inorganic materials 0.000 abstract 4
- 239000001301 oxygen Substances 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 abstract 3
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical compound [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 abstract 3
- 229910000091 aluminium hydride Inorganic materials 0.000 abstract 3
- 150000001414 amino alcohols Chemical class 0.000 abstract 3
- 229910010277 boron hydride Inorganic materials 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 125000005842 heteroatom Chemical group 0.000 abstract 3
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 3
- 229920006395 saturated elastomer Polymers 0.000 abstract 3
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 2
- 235000019253 formic acid Nutrition 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002168 alkylating agent Substances 0.000 abstract 1
- 229940100198 alkylating agent Drugs 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Heat Treatment Of Sheet Steel (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8601295 | 1986-01-30 | ||
| FR8601295A FR2593499B1 (fr) | 1986-01-30 | 1986-01-30 | Aminoalcools, leur procede de preparation et leurs applications, notamment en therapeutique |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK40687D0 DK40687D0 (da) | 1987-01-26 |
| DK40687A true DK40687A (da) | 1987-07-31 |
| DK169538B1 DK169538B1 (da) | 1994-11-28 |
Family
ID=9331637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK040687A DK169538B1 (da) | 1986-01-30 | 1987-01-26 | Aminoalkoholer og syreadditionssalte deraf, fremgangsmåde til deres fremstilling og lægemidler med indhold af sådanne |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4994617A (da) |
| EP (1) | EP0237366B1 (da) |
| JP (1) | JPH089580B2 (da) |
| KR (1) | KR950006891B1 (da) |
| AT (1) | ATE42540T1 (da) |
| AU (1) | AU590664B2 (da) |
| BR (1) | BR1100977A (da) |
| CA (1) | CA1294961C (da) |
| DE (1) | DE3760117D1 (da) |
| DK (1) | DK169538B1 (da) |
| ES (1) | ES2008109B3 (da) |
| FI (1) | FI87068C (da) |
| FR (1) | FR2593499B1 (da) |
| GR (1) | GR3000026T3 (da) |
| IE (1) | IE59448B1 (da) |
| NZ (1) | NZ218988A (da) |
| PT (1) | PT84223B (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4939133A (en) * | 1985-10-01 | 1990-07-03 | Warner-Lambert Company | N-substituted-2-hydroxy-α-oxo-benzeneacetamides and pharmaceutical compositions having activity as modulators of the arachidonic acid cascade |
| US5482947A (en) * | 1990-11-19 | 1996-01-09 | Talley; John J. | Retroviral protease inhibitors |
| US5472970A (en) * | 1992-05-05 | 1995-12-05 | Institut De Recherche Jouveinal S.A. | Allylaminoesters and their application in therapeutics |
| FR2690917B1 (fr) * | 1992-05-05 | 1994-06-17 | Jouveinal Inst Rech | Aminoesters, leur procede de preparation et leur application en therapeutique. |
| FR2690916B1 (fr) * | 1992-05-05 | 1994-06-17 | Jouveinal Inst Rech | Nouveaux enantiomeres derives du (s)-amino-2-(dichloro-3,4-benzyl)-2-propanol-1. |
| US5367094A (en) * | 1993-06-04 | 1994-11-22 | Yukong, Ltd. | Convenient process for the preparation of chiral or racemic phenylalaninols and their N-blocked derivatives |
| FR2761686B1 (fr) * | 1997-04-07 | 1999-05-14 | Sipsy Sa | Nouveau procede de preparation du (+/-)3-(3,4- dichlorophenyl)-2-dimethylamino-2-methyl-propan-1-ol ou cericlamine (inn) |
| US7216702B2 (en) * | 2003-02-28 | 2007-05-15 | Yates Petroleum Corporation | Methods of evaluating undersaturated coalbed methane reservoirs |
| PL1691811T3 (pl) | 2003-12-11 | 2014-12-31 | Sunovion Pharmaceuticals Inc | Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji |
| US7467260B2 (en) * | 2004-10-08 | 2008-12-16 | International Business Machines Corporation | Method and apparatus to purge remote node cache lines to support hot node replace in a computing system |
| CZ301920B6 (cs) * | 2009-06-16 | 2010-07-28 | Zentiva, K. S. | Zpusob výroby (S)-4-methylamino-3-(3,4-dichlorfenyl)butan-1-olu |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3132179A (en) * | 1959-08-27 | 1964-05-05 | Sterling Drug Inc | Ethers of alpha-hydroxymethyl-beta-monocarbocyclic aryl ethyl amines and their preparation |
| US3193581A (en) * | 1961-03-01 | 1965-07-06 | Yamanouchi Pharma Co Ltd | Process of preparing 1-phenyl-2-aminopropane |
| US3573304A (en) * | 1968-12-03 | 1971-03-30 | Delalande Sa | 1-dimethylamino - 3 - methyl-2(pyridyl or pyridazinyl) pentane and the corresponding non-toxic acid addition salts thereof |
| US3706764A (en) * | 1969-04-16 | 1972-12-19 | Yoshitomi Pharmaceutical | Phenethylaminomethyl-chromanones and- thiochromanones |
| US3896166A (en) * | 1970-05-06 | 1975-07-22 | Hoffmann La Roche | Formyl-substituted tyrosine |
| NL7112938A (da) * | 1970-09-30 | 1972-04-05 | ||
| ES399820A1 (es) * | 1971-02-17 | 1975-07-01 | Sandoz Ag | Procedimiento para la obtencion de derivados de amino pro- panol. |
| GB1346401A (en) * | 1971-05-12 | 1974-02-13 | Lepetit Spa | Cardioactive arylaminobutanols |
| US4058642A (en) * | 1973-10-11 | 1977-11-15 | Boehringer Ingelheim Gmbh | 2-Amino-3-(3'-hydroxy-phenyl)-propanols and salts thereof |
| GB1434826A (en) * | 1973-11-14 | 1976-05-05 | Gallardo Antonio Sa | Esters and carbamates of aminoalkanols |
| US4536601A (en) * | 1982-09-28 | 1985-08-20 | Dainippon Pharmaceutical Co., Ltd. | Optically active N-substituted phenylalaninols and use thereof |
-
1986
- 1986-01-30 FR FR8601295A patent/FR2593499B1/fr not_active Expired
-
1987
- 1987-01-09 IE IE6287A patent/IE59448B1/en not_active IP Right Cessation
- 1987-01-19 ES ES87400116T patent/ES2008109B3/es not_active Expired
- 1987-01-19 EP EP87400116A patent/EP0237366B1/fr not_active Expired
- 1987-01-19 DE DE8787400116T patent/DE3760117D1/de not_active Expired
- 1987-01-19 AT AT87400116T patent/ATE42540T1/de not_active IP Right Cessation
- 1987-01-20 NZ NZ218988A patent/NZ218988A/xx unknown
- 1987-01-23 AU AU67959/87A patent/AU590664B2/en not_active Ceased
- 1987-01-26 DK DK040687A patent/DK169538B1/da not_active IP Right Cessation
- 1987-01-28 CA CA000528425A patent/CA1294961C/en not_active Expired - Lifetime
- 1987-01-29 PT PT84223A patent/PT84223B/pt not_active IP Right Cessation
- 1987-01-30 FI FI870418A patent/FI87068C/fi not_active IP Right Cessation
- 1987-01-30 KR KR1019870000797A patent/KR950006891B1/ko not_active Expired - Fee Related
- 1987-01-30 JP JP62018769A patent/JPH089580B2/ja not_active Expired - Fee Related
-
1989
- 1989-07-26 GR GR89400002T patent/GR3000026T3/el unknown
- 1989-12-26 US US07/456,743 patent/US4994617A/en not_active Expired - Lifetime
-
1997
- 1997-05-14 BR BR1100977-2A patent/BR1100977A/pt active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| AU590664B2 (en) | 1989-11-09 |
| GR3000026T3 (en) | 1990-01-19 |
| US4994617A (en) | 1991-02-19 |
| JPS62190150A (ja) | 1987-08-20 |
| KR950006891B1 (ko) | 1995-06-26 |
| NZ218988A (en) | 1990-02-26 |
| FI870418L (fi) | 1987-07-31 |
| BR1100977A (pt) | 1999-10-13 |
| FR2593499A1 (fr) | 1987-07-31 |
| PT84223B (pt) | 1989-05-31 |
| KR870007101A (ko) | 1987-08-14 |
| FI87068B (fi) | 1992-08-14 |
| IE870062L (en) | 1987-07-30 |
| IE59448B1 (en) | 1994-02-23 |
| ES2008109B3 (es) | 1989-07-16 |
| DE3760117D1 (en) | 1989-06-01 |
| DK169538B1 (da) | 1994-11-28 |
| PT84223A (fr) | 1987-02-01 |
| AU6795987A (en) | 1987-08-06 |
| FI870418A0 (fi) | 1987-01-30 |
| FI87068C (fi) | 1992-11-25 |
| CA1294961C (en) | 1992-01-28 |
| JPH089580B2 (ja) | 1996-01-31 |
| FR2593499B1 (fr) | 1988-08-12 |
| ATE42540T1 (de) | 1989-05-15 |
| EP0237366A1 (fr) | 1987-09-16 |
| EP0237366B1 (fr) | 1989-04-26 |
| DK40687D0 (da) | 1987-01-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |
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