FR2761686B1 - Nouveau procede de preparation du (+/-)3-(3,4- dichlorophenyl)-2-dimethylamino-2-methyl-propan-1-ol ou cericlamine (inn) - Google Patents
Nouveau procede de preparation du (+/-)3-(3,4- dichlorophenyl)-2-dimethylamino-2-methyl-propan-1-ol ou cericlamine (inn)Info
- Publication number
- FR2761686B1 FR2761686B1 FR9704311A FR9704311A FR2761686B1 FR 2761686 B1 FR2761686 B1 FR 2761686B1 FR 9704311 A FR9704311 A FR 9704311A FR 9704311 A FR9704311 A FR 9704311A FR 2761686 B1 FR2761686 B1 FR 2761686B1
- Authority
- FR
- France
- Prior art keywords
- dichlorophenyl
- dimethylamino
- pct
- cericlamine
- propan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (22)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9704311A FR2761686B1 (fr) | 1997-04-07 | 1997-04-07 | Nouveau procede de preparation du (+/-)3-(3,4- dichlorophenyl)-2-dimethylamino-2-methyl-propan-1-ol ou cericlamine (inn) |
IL13081398A IL130813A (en) | 1997-04-07 | 1998-04-06 | Process for the preparation of (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-ol or cericlamine (inn) and intermediates thereof |
PT98922719T PT973724E (pt) | 1997-04-07 | 1998-04-06 | Processo novo para a preparacao de (+/-)3- (3,4-diclorofenil)-2-dimetilamino-2-metilpropan-1-ol ou cericlamina (dci) |
AU75259/98A AU728636B2 (en) | 1997-04-07 | 1998-04-06 | Novel process for the preparation of (+/-)3- (3,4-dichlorophenyl)-2- dimethylamino-2-methylpropan-1-ol or cericlamine (INN) |
EA199900906A EA004399B1 (ru) | 1997-04-07 | 1998-04-06 | Способ получения (+/-)3-(3,4-дихлорфенил)-2-диметиламино-2-метилпропан-1-ола или церикламина (inn) |
BR9811459-0A BR9811459A (pt) | 1997-04-07 | 1998-04-06 | "processo para a preparação de (+/-) 3-(3,4-diclorofenil)-2-dimetilamino-2-metilpropan-1-ol , ou cericlamina (inn)" |
SI9830552T SI0973724T1 (en) | 1997-04-07 | 1998-04-06 | Novel process for the preparation of (+/-)3- (3,4-dichlorophenyl)-2- dimethylamino-2-methylpropan-1-ol or cericlamine (inn) |
NZ337588A NZ337588A (en) | 1997-04-07 | 1998-04-06 | Process for the preparation of (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-ol or cericlamine (INN) |
DE69818653T DE69818653T2 (de) | 1997-04-07 | 1998-04-06 | Verfahren zur herstellung von (+/-)3-(3,4-dichlorophenol)-2-dimethylamino-2-methylpropan-1-ol oder cericlamin(inn) |
PL98336041A PL336041A1 (en) | 1997-04-07 | 1998-04-06 | Novel method of obtaining (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-ol or cericlamine (inn) |
DK98922719T DK0973724T3 (da) | 1997-04-07 | 1998-04-06 | Ny fremgangsmåde til fremstilling af (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-ol eller cericlamin (INN) |
ZA9802927A ZA982927B (en) | 1997-04-07 | 1998-04-06 | Novel process for the preparation of (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-01, or cericlamine (inn). |
HU0001753A HUP0001753A3 (en) | 1997-04-07 | 1998-04-06 | Novel process for the preparation of (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-ol or cericlamine (inn) and intermediates of them |
US09/381,118 US6121491A (en) | 1997-04-07 | 1998-04-06 | Process for the preparation of (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-OL or cericlamine (INN) |
CA002277874A CA2277874A1 (fr) | 1997-04-07 | 1998-04-06 | Nouveau procede de preparation du (+/-)-3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropane-1-ol ou de la cericlamine (inn) |
AT98922719T ATE251116T1 (de) | 1997-04-07 | 1998-04-06 | Verfahren zur herstellung von (+/-)3-(3,4- dichlorophenol)-2-dimethylamino-2-methylpropan- - ol oder cericlamin(inn) |
KR1019997009151A KR20010006073A (ko) | 1997-04-07 | 1998-04-06 | (+/-)3-(3,4-디클로로페닐)-2-디메틸아미노-2-메틸프로판-1-올 또는 세리클라민(inn)의 신규 제조 방법 |
SK1360-99A SK284184B6 (sk) | 1997-04-07 | 1998-04-06 | Spôsob prípravy (+/-)3-(3,4-dichlórfenyl)-2-dimetylamino-2- metylpropan-1-olu čiže ceriklamínu (INN) |
ES98922719T ES2209137T3 (es) | 1997-04-07 | 1998-04-06 | Nuevo procedimiento de preparacion de (+/-)-3-(3,4-diclorofenil)-2-dimetilamino-2-metilpropan-1-ol o cericlamina(inn). |
PCT/EP1998/002213 WO1998045248A1 (fr) | 1997-04-07 | 1998-04-06 | Nouveau procede de preparation du (+/-)-3- (3,4-dichlorophenyl)-2- dimethylamino-2-methylpropane-1-ol ou de la cericlamine (inn) |
EP98922719A EP0973724B1 (fr) | 1997-04-07 | 1998-04-06 | Nouveau procede de preparation du (+/-)-3- (3,4-dichlorophenyl)-2- dimethylamino-2-methylpropane-1-ol ou de la cericlamine (inn) |
JP54241598A JP2001519799A (ja) | 1997-04-07 | 1998-04-06 | (+/−)3−(3,4−ジクロロフェニル)−2−ジメチルアミノ−2−メチルプロパン−1−オール又はセリクラミン(inn)の新規な製造法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9704311A FR2761686B1 (fr) | 1997-04-07 | 1997-04-07 | Nouveau procede de preparation du (+/-)3-(3,4- dichlorophenyl)-2-dimethylamino-2-methyl-propan-1-ol ou cericlamine (inn) |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2761686A1 FR2761686A1 (fr) | 1998-10-09 |
FR2761686B1 true FR2761686B1 (fr) | 1999-05-14 |
Family
ID=9505666
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9704311A Expired - Fee Related FR2761686B1 (fr) | 1997-04-07 | 1997-04-07 | Nouveau procede de preparation du (+/-)3-(3,4- dichlorophenyl)-2-dimethylamino-2-methyl-propan-1-ol ou cericlamine (inn) |
Country Status (21)
Country | Link |
---|---|
US (1) | US6121491A (fr) |
EP (1) | EP0973724B1 (fr) |
JP (1) | JP2001519799A (fr) |
KR (1) | KR20010006073A (fr) |
AT (1) | ATE251116T1 (fr) |
AU (1) | AU728636B2 (fr) |
BR (1) | BR9811459A (fr) |
CA (1) | CA2277874A1 (fr) |
DE (1) | DE69818653T2 (fr) |
DK (1) | DK0973724T3 (fr) |
EA (1) | EA004399B1 (fr) |
ES (1) | ES2209137T3 (fr) |
FR (1) | FR2761686B1 (fr) |
HU (1) | HUP0001753A3 (fr) |
IL (1) | IL130813A (fr) |
NZ (1) | NZ337588A (fr) |
PL (1) | PL336041A1 (fr) |
PT (1) | PT973724E (fr) |
SK (1) | SK284184B6 (fr) |
WO (1) | WO1998045248A1 (fr) |
ZA (1) | ZA982927B (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1691811B1 (fr) | 2003-12-11 | 2014-07-23 | Sunovion Pharmaceuticals Inc. | Combinaison d'un sedatif et d'un modulateur des neurotransmetteurs, et methodes permettant d'ameliorer la qualite du sommeil et de traiter la depression |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2378746A1 (fr) * | 1977-01-28 | 1978-08-25 | Synthelabo | Derives d'acides a-amines |
JPS6078921A (ja) * | 1983-10-05 | 1985-05-04 | Toyo Soda Mfg Co Ltd | ハロゲン含有エチルベンゼン誘導体の製造方法 |
JPS61204150A (ja) * | 1985-03-08 | 1986-09-10 | Sagami Chem Res Center | α―ハロ―α―トリフルオロメチル―β―アリールプロピオン酸 |
FR2593499B1 (fr) * | 1986-01-30 | 1988-08-12 | Jouveinal Sa | Aminoalcools, leur procede de preparation et leurs applications, notamment en therapeutique |
US5472970A (en) * | 1992-05-05 | 1995-12-05 | Institut De Recherche Jouveinal S.A. | Allylaminoesters and their application in therapeutics |
FR2690916B1 (fr) * | 1992-05-05 | 1994-06-17 | Jouveinal Inst Rech | Nouveaux enantiomeres derives du (s)-amino-2-(dichloro-3,4-benzyl)-2-propanol-1. |
-
1997
- 1997-04-07 FR FR9704311A patent/FR2761686B1/fr not_active Expired - Fee Related
-
1998
- 1998-04-06 AT AT98922719T patent/ATE251116T1/de not_active IP Right Cessation
- 1998-04-06 SK SK1360-99A patent/SK284184B6/sk unknown
- 1998-04-06 ZA ZA9802927A patent/ZA982927B/xx unknown
- 1998-04-06 BR BR9811459-0A patent/BR9811459A/pt not_active IP Right Cessation
- 1998-04-06 US US09/381,118 patent/US6121491A/en not_active Expired - Fee Related
- 1998-04-06 AU AU75259/98A patent/AU728636B2/en not_active Ceased
- 1998-04-06 PL PL98336041A patent/PL336041A1/xx unknown
- 1998-04-06 DE DE69818653T patent/DE69818653T2/de not_active Expired - Fee Related
- 1998-04-06 CA CA002277874A patent/CA2277874A1/fr not_active Abandoned
- 1998-04-06 WO PCT/EP1998/002213 patent/WO1998045248A1/fr not_active Application Discontinuation
- 1998-04-06 HU HU0001753A patent/HUP0001753A3/hu unknown
- 1998-04-06 EP EP98922719A patent/EP0973724B1/fr not_active Expired - Lifetime
- 1998-04-06 NZ NZ337588A patent/NZ337588A/xx unknown
- 1998-04-06 JP JP54241598A patent/JP2001519799A/ja active Pending
- 1998-04-06 KR KR1019997009151A patent/KR20010006073A/ko not_active Application Discontinuation
- 1998-04-06 DK DK98922719T patent/DK0973724T3/da active
- 1998-04-06 PT PT98922719T patent/PT973724E/pt unknown
- 1998-04-06 ES ES98922719T patent/ES2209137T3/es not_active Expired - Lifetime
- 1998-04-06 EA EA199900906A patent/EA004399B1/ru not_active IP Right Cessation
- 1998-04-06 IL IL13081398A patent/IL130813A/xx active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EA199900906A1 (ru) | 2000-08-28 |
IL130813A0 (en) | 2001-01-28 |
EA004399B1 (ru) | 2004-04-29 |
BR9811459A (pt) | 2000-09-19 |
AU7525998A (en) | 1998-10-30 |
HUP0001753A2 (hu) | 2000-11-28 |
WO1998045248A1 (fr) | 1998-10-15 |
ATE251116T1 (de) | 2003-10-15 |
ZA982927B (en) | 1999-07-15 |
JP2001519799A (ja) | 2001-10-23 |
EP0973724A1 (fr) | 2000-01-26 |
CA2277874A1 (fr) | 1998-10-15 |
PT973724E (pt) | 2004-02-27 |
ES2209137T3 (es) | 2004-06-16 |
SK136099A3 (en) | 2000-05-16 |
US6121491A (en) | 2000-09-19 |
FR2761686A1 (fr) | 1998-10-09 |
KR20010006073A (ko) | 2001-01-15 |
IL130813A (en) | 2003-07-06 |
DE69818653D1 (de) | 2003-11-06 |
NZ337588A (en) | 2000-05-26 |
HUP0001753A3 (en) | 2000-12-28 |
PL336041A1 (en) | 2000-06-05 |
AU728636B2 (en) | 2001-01-11 |
DE69818653T2 (de) | 2004-08-19 |
SK284184B6 (sk) | 2004-10-05 |
DK0973724T3 (da) | 2004-02-02 |
EP0973724B1 (fr) | 2003-10-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |
Effective date: 20051230 |