DK1685243T3 - Immortaliserede fuglecellelinjer til virusproduktion - Google Patents

Immortaliserede fuglecellelinjer til virusproduktion

Info

Publication number
DK1685243T3
DK1685243T3 DK04798154T DK04798154T DK1685243T3 DK 1685243 T3 DK1685243 T3 DK 1685243T3 DK 04798154 T DK04798154 T DK 04798154T DK 04798154 T DK04798154 T DK 04798154T DK 1685243 T3 DK1685243 T3 DK 1685243T3
Authority
DK
Denmark
Prior art keywords
cell lines
immortalized
virus production
bird cell
production
Prior art date
Application number
DK04798154T
Other languages
Danish (da)
English (en)
Inventor
Volker Sandig
Ingo Jordan
Original Assignee
Probiogen Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34400514&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1685243(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Probiogen Ag filed Critical Probiogen Ag
Application granted granted Critical
Publication of DK1685243T3 publication Critical patent/DK1685243T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0091—Purification or manufacturing processes for gene therapy compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10211—Aviadenovirus, e.g. fowl adenovirus A
    • C12N2710/10222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10211—Aviadenovirus, e.g. fowl adenovirus A
    • C12N2710/10251—Methods of production or purification of viral material
    • C12N2710/10252—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material
    • C12N2710/10352—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Manufacturing & Machinery (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK04798154T 2003-11-03 2004-11-03 Immortaliserede fuglecellelinjer til virusproduktion DK1685243T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03025158A EP1528101A1 (fr) 2003-11-03 2003-11-03 Lignées cellulaires aviaires immortalisées pour la production de virus
PCT/EP2004/052789 WO2005042728A2 (fr) 2003-11-03 2004-11-03 Lignees de cellules aviaires immortalisees pour la production de virus

Publications (1)

Publication Number Publication Date
DK1685243T3 true DK1685243T3 (da) 2008-10-20

Family

ID=34400514

Family Applications (2)

Application Number Title Priority Date Filing Date
DK04798154T DK1685243T3 (da) 2003-11-03 2004-11-03 Immortaliserede fuglecellelinjer til virusproduktion
DK08101999.4T DK1939281T4 (da) 2003-11-03 2004-11-03 Immortaliserede andecellelinjer til virusproduktion

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK08101999.4T DK1939281T4 (da) 2003-11-03 2004-11-03 Immortaliserede andecellelinjer til virusproduktion

Country Status (18)

Country Link
US (2) US8940534B2 (fr)
EP (4) EP1528101A1 (fr)
JP (1) JP4658953B2 (fr)
KR (1) KR101027755B1 (fr)
CN (1) CN1934243B (fr)
AT (2) ATE460473T1 (fr)
AU (1) AU2004285089B2 (fr)
BR (1) BRPI0415622B8 (fr)
CA (1) CA2544462C (fr)
CY (1) CY1110272T1 (fr)
DE (2) DE602004025996D1 (fr)
DK (2) DK1685243T3 (fr)
ES (1) ES2309578T3 (fr)
PL (1) PL1685243T3 (fr)
PT (1) PT1685243E (fr)
RU (1) RU2359999C2 (fr)
SI (1) SI1685243T1 (fr)
WO (1) WO2005042728A2 (fr)

Families Citing this family (125)

* Cited by examiner, † Cited by third party
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BRPI0618254A2 (pt) 2005-11-04 2011-08-23 Novartis Vaccines & Diagnostic emulsões com agente tensoativo de fase aquosa livre para fornecer adjuvante às vacinas contra influenza dividido
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EP2098590A1 (fr) 2008-03-04 2009-09-09 ProBioGen AG Souche cellulaire de Rousettus en tant que cellule hôte pour l'amplification de pathogènes
WO2009109377A1 (fr) 2008-03-04 2009-09-11 Probiogen Ag Lignée cellulaire provenant de rousettus comme cellule hôte pour l'amplification de pathogènes
ES2535101T3 (es) 2008-03-18 2015-05-05 Novartis Ag Mejoras en la preparación de antígenos en vacuna de virus de la gripe
EP2310494A1 (fr) * 2008-06-25 2011-04-20 ProBioGen AG Lignée cellulaire pour la propagation d'alphavirus très atténués
EP2199385A1 (fr) 2008-12-16 2010-06-23 ProBioGen AG Activation spécifique et persistante de réponse de choc thermique dans les lignées cellulaires utilisant un facteur viral
WO2010079081A1 (fr) 2009-01-07 2010-07-15 Glaxosmithkline Biologicals S.A. Procédés de récupération d'un virus ou d'un antigène viral produit par culture cellulaire
JP5843615B2 (ja) 2009-02-06 2016-01-13 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 密度勾配超遠心分離によるウイルスまたはウイルス抗原の精製
ES2552383T3 (es) 2009-02-10 2015-11-27 Novartis Ag Regímenes de vacuna de la gripe para cepas asociadas a pandemias
US20120093860A1 (en) 2009-02-10 2012-04-19 Novartis Ag Influenza vaccines with increased amounts of h3 antigen
ES2608841T3 (es) 2009-02-10 2017-04-17 Seqirus UK Limited Vacunas contra la gripe con cantidades reducidas de escualeno
CN102548577A (zh) 2009-04-27 2012-07-04 诺华有限公司 用于抵抗流感的佐剂疫苗
WO2011008974A2 (fr) 2009-07-15 2011-01-20 Novartis Ag Compositions à base de protéine f du vrs et procédés de fabrication associés
JP2013504556A (ja) 2009-09-10 2013-02-07 ノバルティス アーゲー 気道疾患に対する組み合わせワクチン
WO2011040527A1 (fr) * 2009-09-30 2011-04-07 国立大学法人帯広畜産大学 OISEAU TRANSGÉNIQUE CAPABLE D'EXPRIMER UN ÉPITOPE DE α-GALACTOSE, VIRUS ET VACCIN
US20120309056A1 (en) 2010-02-04 2012-12-06 Leon Arnaud Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells
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EP2556151A1 (fr) 2010-04-07 2013-02-13 Novartis AG Procédé de génération de pseudo-particules virales de parvovirus b19
EP2563909A1 (fr) 2010-04-26 2013-03-06 Novartis AG Production améliorée de particules de réplicon de virus dans des cellules d'encapsidation
EP2566958B1 (fr) 2010-05-03 2015-12-30 GlaxoSmithKline Biologicals S.A. Procédé pour l'inactivation du virus de la grippe
JP6072677B2 (ja) 2010-05-06 2017-02-01 ノバルティス アーゲー 微生物の不活化のための有機ペルオキシド化合物
JP5876036B2 (ja) 2010-05-21 2016-03-02 ノバルティス アーゲー インフルエンザウイルス再集合方法
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BR112012030619A2 (pt) 2010-06-01 2019-09-24 Novartis Ag concentração de antígenos de vacina influenza sem liofilização.
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WO2012023044A1 (fr) 2010-08-20 2012-02-23 Novartis Ag Ensembles d'aiguilles solubles pour l'administration de vaccins contre la grippe
EP3520813B1 (fr) 2010-10-11 2023-04-19 GlaxoSmithKline Biologicals S.A. Plateformes de délivrance d'antigènes
EP3257943B1 (fr) * 2010-11-02 2019-09-11 Helmholtz-Zentrum für Infektionsforschung GmbH Procédés et vecteurs pour l'immortalisation de cellules
WO2012095514A1 (fr) 2011-01-14 2012-07-19 Vivalis Système de production de protéines recombinantes
PT2667892T (pt) 2011-01-26 2019-06-07 Glaxosmithkline Biologicals Sa Regime de imunização contra o vsr
EP2707385B1 (fr) 2011-05-13 2017-09-20 GlaxoSmithKline Biologicals SA Antigènes de pré-fusion f du vrs
JP2014518080A (ja) 2011-06-27 2014-07-28 バルネバ 細胞のスクリーニング方法
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JP2014520807A (ja) 2011-07-06 2014-08-25 ノバルティス アーゲー 免疫原性組成物およびその使用
JP6305925B2 (ja) 2011-10-11 2018-04-18 ノバルティス アーゲー 組換え自己複製ポリシストロニックｒｎａ分子
EP2766385A2 (fr) 2011-10-12 2014-08-20 Novartis AG Antigènes de cmv et leurs utilisations
GB201216121D0 (en) 2012-09-10 2012-10-24 Novartis Ag Sample quantification by disc centrifugation
EP2768528A1 (fr) 2011-10-20 2014-08-27 Novartis AG Vaccins avec adjuvant contre le virus grippal b pour primo-vaccination pédiatrique
EP2660316A1 (fr) 2012-05-02 2013-11-06 Helmholtz-Zentrum für Infektionsforschung GmbH Lignée cellulaire aviaire et son utilisation dans la production de protéines
CN104853770A (zh) 2012-07-06 2015-08-19 诺华股份有限公司 免疫原性组合物及其应用
GB201218195D0 (en) 2012-10-10 2012-11-21 Istituto Zooprofilattico Sperimentale Delle Venezie Composition
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CN103060376A (zh) * 2012-12-11 2013-04-24 上海实验动物研究中心 一种禽腺病毒转移载体及其制备方法
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JP2017512839A (ja) * 2014-04-02 2017-05-25 アレクシオン ファーマシューティカルズ， インコーポレイテッド 治療用タンパク質の生産
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DK3169341T3 (da) 2014-07-16 2019-08-05 Transgene Sa Onkolytisk virus til ekspression af immun-checkpoint-modulatorer
CN107002044B (zh) * 2014-12-04 2020-10-30 英特维特国际股份有限公司 永生化鸡胚成纤维细胞
EP3031822A1 (fr) 2014-12-08 2016-06-15 Novartis AG Antigènes du cytomégalovirus
US20170369854A1 (en) 2014-12-16 2017-12-28 Glaxosmithkline Biologicals Sa A method for a large scale virus purification
JP6956635B2 (ja) 2014-12-17 2021-11-02 フンダシオン パラ ラ インベスティガシオン メディカ アプリカダ ウィルソン病及び他の状態の処置に使用するための核酸構築物及び遺伝子治療ベクター
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