DK160554C - Substituerede phenylalkyl(piperazinyl eller homopiperazinyl)-alkyl-(urinstoffer eller thiourinstoffer), analogifremgangsmaade til fremstilling heraf og farmaceutisk praeparat indeholdende en saadan forbindelse - Google Patents

Substituerede phenylalkyl(piperazinyl eller homopiperazinyl)-alkyl-(urinstoffer eller thiourinstoffer), analogifremgangsmaade til fremstilling heraf og farmaceutisk praeparat indeholdende en saadan forbindelse

Info

Publication number
DK160554C
DK160554C DK294084A DK294084A DK160554C DK 160554 C DK160554 C DK 160554C DK 294084 A DK294084 A DK 294084A DK 294084 A DK294084 A DK 294084A DK 160554 C DK160554 C DK 160554C
Authority
DK
Denmark
Prior art keywords
preparation
thiour
homopiperazinyl
piperazinyl
urine
Prior art date
Application number
DK294084A
Other languages
English (en)
Other versions
DK294084A (da
DK160554B (da
DK294084D0 (da
Inventor
John P Devlin
Karl D Hargrave
Edward L Barsumian
Genus J Possanza
Original Assignee
Boehringer Ingelheim Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Ltd filed Critical Boehringer Ingelheim Ltd
Publication of DK294084D0 publication Critical patent/DK294084D0/da
Publication of DK294084A publication Critical patent/DK294084A/da
Publication of DK160554B publication Critical patent/DK160554B/da
Application granted granted Critical
Publication of DK160554C publication Critical patent/DK160554C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK294084A 1983-06-16 1984-06-15 Substituerede phenylalkyl(piperazinyl eller homopiperazinyl)-alkyl-(urinstoffer eller thiourinstoffer), analogifremgangsmaade til fremstilling heraf og farmaceutisk praeparat indeholdende en saadan forbindelse DK160554C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50483783A 1983-06-16 1983-06-16
US50483783 1983-06-16

Publications (4)

Publication Number Publication Date
DK294084D0 DK294084D0 (da) 1984-06-15
DK294084A DK294084A (da) 1984-12-17
DK160554B DK160554B (da) 1991-03-25
DK160554C true DK160554C (da) 1991-09-09

Family

ID=24007953

Family Applications (1)

Application Number Title Priority Date Filing Date
DK294084A DK160554C (da) 1983-06-16 1984-06-15 Substituerede phenylalkyl(piperazinyl eller homopiperazinyl)-alkyl-(urinstoffer eller thiourinstoffer), analogifremgangsmaade til fremstilling heraf og farmaceutisk praeparat indeholdende en saadan forbindelse

Country Status (25)

Country Link
EP (1) EP0129207B1 (da)
JP (1) JPS6075469A (da)
KR (1) KR890000175B1 (da)
AR (1) AR242377A1 (da)
AT (1) ATE33023T1 (da)
AU (1) AU565041B2 (da)
CA (1) CA1219260A (da)
CS (1) CS244821B2 (da)
DD (1) DD223710A5 (da)
DE (1) DE3469896D1 (da)
DK (1) DK160554C (da)
ES (3) ES8506651A1 (da)
FI (1) FI76327C (da)
GR (1) GR82367B (da)
HU (1) HU192409B (da)
IE (1) IE59034B1 (da)
IL (1) IL72123A (da)
NO (1) NO161618C (da)
NZ (1) NZ208535A (da)
PH (1) PH24059A (da)
PL (2) PL146314B1 (da)
PT (1) PT78729B (da)
SU (2) SU1542415A3 (da)
YU (2) YU104584A (da)
ZA (1) ZA844527B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661481A (en) * 1983-06-16 1987-04-28 Boehringer Ingelheim Pharmaceuticals, Inc Substituted phenylalkylhomopiperazinylpropyl(ureas or thioureas) useful for treatment of immulogical, inflammatory and allergic disorders
FR2601366B1 (fr) * 1986-07-10 1988-11-25 Andre Buzas Derives de la benzhydryloxyethyl-piperazine, procedes d'obtention et de compositions pharmaceutiques les contenant.
JP2722250B2 (ja) * 1989-05-30 1998-03-04 興和株式会社 新規なジアミン化合物及びこれを含有する脳機能障害改善剤
JPH0525145A (ja) * 1991-07-15 1993-02-02 Mochida Pharmaceut Co Ltd アレルギー性疾患治療剤
JP3719612B2 (ja) * 1993-06-14 2005-11-24 塩野義製薬株式会社 ヘテロ環を含有する尿素誘導体
ITRM20060090A1 (it) * 2006-02-22 2007-08-23 Sigma Tau Ind Farmaceuti Nuovi composti inibitori cpt a livello del snc come farmaci antidiabetici e o antiobesita
KR20150076264A (ko) 2007-08-22 2015-07-06 아스트라제네카 아베 시클로프로필 아미드 유도체
TW201039825A (en) * 2009-02-20 2010-11-16 Astrazeneca Ab Cyclopropyl amide derivatives 983
MX336333B (es) 2010-02-18 2016-01-15 Astrazeneca Ab Nueva forma cristalina de un derivado de ciclopropilbenzamida.
RU2771280C2 (ru) * 2016-07-13 2022-04-29 Лео Фарма А/С Гетероароматические модуляторы ретинол-связанного орфанного рецептора гамма

Also Published As

Publication number Publication date
IE59034B1 (en) 1993-12-15
HU192409B (en) 1987-06-29
EP0129207A3 (en) 1985-07-31
DE3469896D1 (en) 1988-04-21
IE841499L (en) 1984-12-16
ES533448A0 (es) 1985-08-01
NO842417L (no) 1984-12-17
NO161618B (no) 1989-05-29
HUT34464A (en) 1985-03-28
AR242377A1 (es) 1993-03-31
NZ208535A (en) 1987-02-20
EP0129207A2 (en) 1984-12-27
PT78729B (en) 1986-10-21
FI76327C (fi) 1988-10-10
JPS6075469A (ja) 1985-04-27
DD223710A5 (de) 1985-06-19
DK294084A (da) 1984-12-17
FI842408A (fi) 1984-12-17
PL146314B1 (en) 1989-01-31
CA1219260A (en) 1987-03-17
EP0129207B1 (en) 1988-03-16
PL147413B1 (en) 1989-05-31
PT78729A (en) 1984-07-01
GR82367B (da) 1984-12-13
PH24059A (en) 1990-03-05
ZA844527B (en) 1986-02-26
ES8506651A1 (es) 1985-08-01
FI76327B (fi) 1988-06-30
PL248207A1 (en) 1985-08-13
PL252851A1 (en) 1986-07-01
DK160554B (da) 1991-03-25
CS244821B2 (en) 1986-08-14
ES8601928A1 (es) 1985-11-01
ES8600255A1 (es) 1985-09-16
ES537662A0 (es) 1985-09-16
SU1542415A3 (ru) 1990-02-07
KR850000422A (ko) 1985-02-27
ATE33023T1 (de) 1988-04-15
DK294084D0 (da) 1984-06-15
FI842408A0 (fi) 1984-06-14
NO161618C (no) 1989-09-06
IL72123A0 (en) 1984-10-31
YU150186A (en) 1987-06-30
SU1387877A3 (ru) 1988-04-07
AU565041B2 (en) 1987-09-03
JPH0469147B2 (da) 1992-11-05
IL72123A (en) 1987-09-16
AU2940484A (en) 1984-12-20
KR890000175B1 (ko) 1989-03-09
ES537661A0 (es) 1985-11-01
YU104584A (en) 1986-12-31

Similar Documents

Publication Publication Date Title
DK445084A (da) 6-flour-1,4-dihydro-4-oxo-7-substituerede piperazinylquinolin-3-carboxylsyrederivater, fremgangsmaade til fremstilling af samme og farcaceutiske sammensaetninger indeholdende samme
DE3775208D1 (de) Steroidenheilmittelzubereitung zur aeusserlichen verwendung.
DK573384A (da) Sphingosinderivater, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende disse derivater
DK165949C (da) 1,4-dihydropyridinderivater, fremgangsmaader til fremstilling deraf og farmaceutiske praeparater indeholdende forbindelserne
NO176514C (no) Belagte keramiske sfæroider og fremgangsmåte til fremstilling derav
NO167810C (no) Analogifremgangsmaate til fremstilling av insulinderivater.
DK164546C (da) Analogifremgangsmaade til fremstilling af 1-substituerede piperid-4-yl-urinstof- og -thiourinstof-derivater
NO854194L (no) Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende antracyklinglykosider.
IL64665A (en) 4-amino-6,7-dimethoxy-2-piperazino-quinazoline derivatives,their preparation and pharmaceutical compositions containing them
DK160554C (da) Substituerede phenylalkyl(piperazinyl eller homopiperazinyl)-alkyl-(urinstoffer eller thiourinstoffer), analogifremgangsmaade til fremstilling heraf og farmaceutisk praeparat indeholdende en saadan forbindelse
ATE98643T1 (de) Aralkylaminalkoxyphenyl-derivate, verfahren zur herstellung und sie enthaltende zusammensetzungen.
DK127588D0 (da) Beta-aminoethylsubstituerede phenylforbindelser, farmaceutiske praeparater indeholdende samme og fremgangsmaader til fremstilling af saadanne forbindelser
DK507084D0 (da) Hydroxybenzenderivater, fremgangsmaade til fremstilling heraf og farmaceutisk praeparat indeholdende et saadant derivat
DK164055C (da) 2-thioxo-5-pyrimidincarboxamider, farmaceutisk middel indeholdende disse til at inducere regression af leukaemi og haemning af vaekst af tumorer og fremgangsmaader til deres fremstilling
NO158417C (no) Analogifremgangsmaate for fremstilling av farmakologisk aktive urinstoffer og tiourinstoffer.
ATE74487T1 (de) Verfahren zur herstellung und verwendung fester, pflanzenwirksamer zusammensetzungen.
NO845105L (no) Fremgangsmaate til fremstilling av glykosal, alkylglykosaler og acetater derav
DK164865C (da) Silibininderivater, fremgangsmaade til fremstilling deraf samt farmaceutisk middel indeholdende silibininderivaterne
IL52841A (en) 7-substituted aminoacetamido oxadethia-cephalosporins,processes for the reparation thereof,pharmaceutical or veterinary compositions containing the same and method of inhibiting the growth of bacteria therewith
DK158514C (da) Analogifremgangsmaade til fremstilling af piperazinyl- eller homopiperazinylderivater
IL75823A0 (en) 2-benzyl-4-(4-pyridyl)thiazoles and derivatives thereof,their preparation and pharmaceutical compositions containing them
IL71891A (en) Aryloxycycloalkanolamino-alkyl aryl ketones,pharmaceutical compositions comprising them and process for the preparation of some such compounds
ZA811479B (en) Quinoline derivatives, pharmaceutical compositions containg such compounds and methods for the preparation of these compounds
DK190589D0 (da) Quinolin-3-carboxylsyreforbindelser, fremgangsmaade til fremstilling heraf og farmaceutisk middel omfattende samme
DK525187A (da) Imidazooe4,5-baapyridinon-2-derivater, fremgangsmaade til fremstilling af og laegemidler indeholdende saadanne derivater

Legal Events

Date Code Title Description
PBP Patent lapsed