NO161618C - Analogifremgangsm te for fremstilling av terapeutisk aktive fenylalkyl-(piperazinyl eller homopiperazinyl)-alkyl-(urinstoff eller tiourinstoff)-derivater. - Google Patents

Analogifremgangsm te for fremstilling av terapeutisk aktive fenylalkyl-(piperazinyl eller homopiperazinyl)-alkyl-(urinstoff eller tiourinstoff)-derivater.

Info

Publication number
NO161618C
NO161618C NO842417A NO842417A NO161618C NO 161618 C NO161618 C NO 161618C NO 842417 A NO842417 A NO 842417A NO 842417 A NO842417 A NO 842417A NO 161618 C NO161618 C NO 161618C
Authority
NO
Norway
Prior art keywords
tiourine
homopiperazinyl
phenylalkyl
piperazinyl
urine
Prior art date
Application number
NO842417A
Other languages
English (en)
Norwegian (no)
Other versions
NO161618B (no
NO842417L (no
Inventor
John P Devlin
Karl D Hargrave
Edward L Barsumian
Genus J Possanza
Original Assignee
Boehringer Ingelheim Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Ltd filed Critical Boehringer Ingelheim Ltd
Publication of NO842417L publication Critical patent/NO842417L/no
Publication of NO161618B publication Critical patent/NO161618B/no
Publication of NO161618C publication Critical patent/NO161618C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO842417A 1983-06-16 1984-06-15 Analogifremgangsm te for fremstilling av terapeutisk aktive fenylalkyl-(piperazinyl eller homopiperazinyl)-alkyl-(urinstoff eller tiourinstoff)-derivater. NO161618C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50483783A 1983-06-16 1983-06-16

Publications (3)

Publication Number Publication Date
NO842417L NO842417L (no) 1984-12-17
NO161618B NO161618B (no) 1989-05-29
NO161618C true NO161618C (no) 1989-09-06

Family

ID=24007953

Family Applications (1)

Application Number Title Priority Date Filing Date
NO842417A NO161618C (no) 1983-06-16 1984-06-15 Analogifremgangsm te for fremstilling av terapeutisk aktive fenylalkyl-(piperazinyl eller homopiperazinyl)-alkyl-(urinstoff eller tiourinstoff)-derivater.

Country Status (25)

Country Link
EP (1) EP0129207B1 (da)
JP (1) JPS6075469A (da)
KR (1) KR890000175B1 (da)
AR (1) AR242377A1 (da)
AT (1) ATE33023T1 (da)
AU (1) AU565041B2 (da)
CA (1) CA1219260A (da)
CS (1) CS244821B2 (da)
DD (1) DD223710A5 (da)
DE (1) DE3469896D1 (da)
DK (1) DK160554C (da)
ES (3) ES8506651A1 (da)
FI (1) FI76327C (da)
GR (1) GR82367B (da)
HU (1) HU192409B (da)
IE (1) IE59034B1 (da)
IL (1) IL72123A (da)
NO (1) NO161618C (da)
NZ (1) NZ208535A (da)
PH (1) PH24059A (da)
PL (2) PL147413B1 (da)
PT (1) PT78729B (da)
SU (2) SU1542415A3 (da)
YU (2) YU104584A (da)
ZA (1) ZA844527B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661481A (en) * 1983-06-16 1987-04-28 Boehringer Ingelheim Pharmaceuticals, Inc Substituted phenylalkylhomopiperazinylpropyl(ureas or thioureas) useful for treatment of immulogical, inflammatory and allergic disorders
FR2601366B1 (fr) * 1986-07-10 1988-11-25 Andre Buzas Derives de la benzhydryloxyethyl-piperazine, procedes d'obtention et de compositions pharmaceutiques les contenant.
JP2722250B2 (ja) * 1989-05-30 1998-03-04 興和株式会社 新規なジアミン化合物及びこれを含有する脳機能障害改善剤
JPH0525145A (ja) * 1991-07-15 1993-02-02 Mochida Pharmaceut Co Ltd アレルギー性疾患治療剤
JP3719612B2 (ja) * 1993-06-14 2005-11-24 塩野義製薬株式会社 ヘテロ環を含有する尿素誘導体
ITRM20060090A1 (it) * 2006-02-22 2007-08-23 Sigma Tau Ind Farmaceuti Nuovi composti inibitori cpt a livello del snc come farmaci antidiabetici e o antiobesita
PT2195293E (pt) 2007-08-22 2014-01-21 Astrazeneca Ab Derivados da ciclopropilamida
TW201039825A (en) * 2009-02-20 2010-11-16 Astrazeneca Ab Cyclopropyl amide derivatives 983
RU2012136148A (ru) 2010-02-18 2014-03-27 Астразенека Аб Новая кристаллическая форма производного циклопропилбензамида
RU2771280C2 (ru) * 2016-07-13 2022-04-29 Лео Фарма А/С Гетероароматические модуляторы ретинол-связанного орфанного рецептора гамма

Also Published As

Publication number Publication date
DK160554C (da) 1991-09-09
HU192409B (en) 1987-06-29
ATE33023T1 (de) 1988-04-15
KR850000422A (ko) 1985-02-27
IE59034B1 (en) 1993-12-15
SU1542415A3 (ru) 1990-02-07
ES8600255A1 (es) 1985-09-16
NO161618B (no) 1989-05-29
PT78729B (en) 1986-10-21
EP0129207A3 (en) 1985-07-31
ES537662A0 (es) 1985-09-16
NO842417L (no) 1984-12-17
PL252851A1 (en) 1986-07-01
CS244821B2 (en) 1986-08-14
JPH0469147B2 (da) 1992-11-05
PL248207A1 (en) 1985-08-13
DK294084D0 (da) 1984-06-15
AU2940484A (en) 1984-12-20
AR242377A1 (es) 1993-03-31
ES533448A0 (es) 1985-08-01
SU1387877A3 (ru) 1988-04-07
EP0129207B1 (en) 1988-03-16
ES8506651A1 (es) 1985-08-01
DE3469896D1 (en) 1988-04-21
JPS6075469A (ja) 1985-04-27
PH24059A (en) 1990-03-05
CA1219260A (en) 1987-03-17
FI76327B (fi) 1988-06-30
DK160554B (da) 1991-03-25
PL146314B1 (en) 1989-01-31
PT78729A (en) 1984-07-01
GR82367B (da) 1984-12-13
PL147413B1 (en) 1989-05-31
YU150186A (en) 1987-06-30
FI842408A (fi) 1984-12-17
IE841499L (en) 1984-12-16
HUT34464A (en) 1985-03-28
EP0129207A2 (en) 1984-12-27
DD223710A5 (de) 1985-06-19
IL72123A (en) 1987-09-16
NZ208535A (en) 1987-02-20
ZA844527B (en) 1986-02-26
DK294084A (da) 1984-12-17
YU104584A (en) 1986-12-31
KR890000175B1 (ko) 1989-03-09
FI76327C (fi) 1988-10-10
ES8601928A1 (es) 1985-11-01
ES537661A0 (es) 1985-11-01
IL72123A0 (en) 1984-10-31
FI842408A0 (fi) 1984-06-14
AU565041B2 (en) 1987-09-03

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