DK142289B - Analogifremgangsmåde til fremstilling af D-homopregn-4-en-3,20-dioner. - Google Patents

Analogifremgangsmåde til fremstilling af D-homopregn-4-en-3,20-dioner. Download PDF

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Publication number
DK142289B
DK142289B DK531173AA DK531173A DK142289B DK 142289 B DK142289 B DK 142289B DK 531173A A DK531173A A DK 531173AA DK 531173 A DK531173 A DK 531173A DK 142289 B DK142289 B DK 142289B
Authority
DK
Denmark
Prior art keywords
hydroxy
homosteroid
general formula
dione
homopregn
Prior art date
Application number
DK531173AA
Other languages
Danish (da)
English (en)
Other versions
DK142289C (pl
DK531173A (pl
Inventor
Marcel Mueller
Leo Alig
Andor Fuerst
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK170673AA external-priority patent/DK135722B/da
Priority to CH167679A priority Critical patent/CH616950A5/de
Priority claimed from CH1376473A external-priority patent/CH596237A5/xx
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to DK531173AA priority patent/DK142289B/da
Priority to SE7313269A priority patent/SE418402B/xx
Priority to NO3800/73A priority patent/NO140672C/no
Priority to ZA00745316A priority patent/ZA745316B/xx
Priority to IL45516A priority patent/IL45516A/xx
Priority to AU72633/74A priority patent/AU480546B2/en
Priority to US05/501,558 priority patent/US3939193A/en
Priority to YU2430/74A priority patent/YU36745B/xx
Priority to CA209,719A priority patent/CA1031323A/en
Priority to IE1963/74A priority patent/IE40178B1/xx
Priority to FI2767/74A priority patent/FI54604C/fi
Priority to PH16322A priority patent/PH11410A/en
Priority to NL7412590A priority patent/NL7412590A/xx
Priority to DD181284A priority patent/DD115354A5/xx
Priority to EG423/74A priority patent/EG11212A/xx
Priority to FR7432164A priority patent/FR2244474B1/fr
Priority to JP49108925A priority patent/JPS595600B2/ja
Priority to LU70979A priority patent/LU70979A1/xx
Priority to CS7600005074A priority patent/CS179948B2/cs
Priority to PL1974174320A priority patent/PL95291B1/pl
Priority to CS7600005076A priority patent/CS179950B2/cs
Priority to GB4170774A priority patent/GB1445945A/en
Priority to PL1974182346A priority patent/PL95272B1/pl
Priority to PL1974172345D priority patent/PL95273B1/pl
Priority to HU74HO00001726A priority patent/HU172657B/hu
Priority to AT771974A priority patent/AT335087B/de
Priority to PL1974182348A priority patent/PL95270B1/pl
Priority to ES430370A priority patent/ES430370A1/es
Priority to PL1974182344A priority patent/PL95271B1/pl
Priority to DE2445817A priority patent/DE2445817C2/de
Priority to CS7400006584A priority patent/CS179927B2/cs
Priority to BE148858A priority patent/BE820304A/xx
Priority to CS7600005075A priority patent/CS179949B2/cs
Priority to SU752145928A priority patent/SU683630A3/ru
Priority to SU752145930A priority patent/SU634676A3/ru
Priority to SU752145940A priority patent/SU635875A3/ru
Priority to SU752145938A priority patent/SU867316A3/ru
Priority to SU752145939A priority patent/SU612638A3/ru
Priority to SU7502145936A priority patent/SU564814A3/ru
Publication of DK531173A publication Critical patent/DK531173A/da
Priority to AR259890A priority patent/AR211000A1/es
Priority to US05/629,439 priority patent/US4026923A/en
Priority to AT561376A priority patent/AT348165B/de
Priority to AT561476A priority patent/AT346507B/de
Priority to ES455100A priority patent/ES455100A1/es
Priority to ES455101A priority patent/ES455101A1/es
Priority to ES455105A priority patent/ES455105A1/es
Priority to ES455103A priority patent/ES455103A1/es
Priority to ES455106A priority patent/ES455106A1/es
Priority to ES455107A priority patent/ES455107A1/es
Priority to ES455104A priority patent/ES455104A1/es
Priority to ES455102A priority patent/ES455102A1/es
Publication of DK142289B publication Critical patent/DK142289B/da
Priority to YU2966/80A priority patent/YU36979B/xx
Priority to YU2967/80A priority patent/YU36980B/xx
Application granted granted Critical
Publication of DK142289C publication Critical patent/DK142289C/da
Priority to JP57147864A priority patent/JPS596880B2/ja
Priority to JP57147865A priority patent/JPS5928560B2/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK531173AA 1973-03-28 1973-09-28 Analogifremgangsmåde til fremstilling af D-homopregn-4-en-3,20-dioner. DK142289B (da)

Priority Applications (56)

Application Number Priority Date Filing Date Title
CH167679A CH616950A5 (en) 1973-03-28 1973-09-26 Process for the preparation of D-homosteroids.
DK531173AA DK142289B (da) 1973-03-28 1973-09-28 Analogifremgangsmåde til fremstilling af D-homopregn-4-en-3,20-dioner.
SE7313269A SE418402B (sv) 1973-03-28 1973-09-28 Vidareutveckling av forfaranden enligt patentet 404 530 for framstellning av d-homosteroider av pregnanserien
NO3800/73A NO140672C (no) 1973-03-28 1973-09-28 Analogifremgangsmaate ved fremstilling av nye anti-inflammatorisk virksomme steroider
ZA00745316A ZA745316B (en) 1973-03-28 1974-08-19 Novel steroids
IL45516A IL45516A (en) 1973-03-28 1974-08-22 3,20-dioxo-17aalpha-hydroxy-d-homopregn-4-enes their manufacture and pharmaceutical compositions containing them
AU72633/74A AU480546B2 (en) 1973-09-26 1974-08-23 Novel steroids
US05/501,558 US3939193A (en) 1973-03-28 1974-08-29 D-Homosteroids
YU2430/74A YU36745B (en) 1973-03-28 1974-09-09 Process for obtaining new d-homosteroids
CA209,719A CA1031323A (en) 1973-03-28 1974-09-20 D-homo-steroids
IE1963/74A IE40178B1 (en) 1973-03-28 1974-09-23 Steroids of the d-homopregnange series
FI2767/74A FI54604C (fi) 1973-03-28 1974-09-23 Foerfarande foer framstaellning av endokrint verksamma nya d-homosteroider
PH16322A PH11410A (en) 1973-03-28 1974-09-23 Novel steroids
NL7412590A NL7412590A (nl) 1973-03-28 1974-09-24 Werkwijze voor het bereiden van nieuwe osteroiden.
DD181284A DD115354A5 (pl) 1973-03-28 1974-09-24
EG423/74A EG11212A (en) 1973-03-28 1974-09-24 Method for preparation of new d homo steroids
FR7432164A FR2244474B1 (pl) 1973-03-28 1974-09-24
JP49108925A JPS595600B2 (ja) 1973-03-28 1974-09-24 Ｄ − ホモステロイド ノ セイゾウホウホウ
LU70979A LU70979A1 (pl) 1973-03-28 1974-09-24
PL1974182348A PL95270B1 (pl) 1973-03-28 1974-09-25
PL1974174320A PL95291B1 (pl) 1973-03-28 1974-09-25 Sposob wytwarzania nowych d-homosteroidow
CS7600005076A CS179950B2 (en) 1973-03-28 1974-09-25 Method for production of novel d-homopregn-4-ene 3,20-diones
GB4170774A GB1445945A (en) 1973-03-28 1974-09-25 Steroids of the d-homo-pregnane series
PL1974182346A PL95272B1 (pl) 1973-03-28 1974-09-25 Sposob wytwarzania nowych d-homosteroidow
PL1974172345D PL95273B1 (pl) 1973-03-28 1974-09-25 Sposob wytwarzania nowych d-homosteroidow
HU74HO00001726A HU172657B (hu) 1973-03-28 1974-09-25 Sposob poluchenija novykh d-gomo-steroidov
AT771974A AT335087B (de) 1973-03-28 1974-09-25 Verfahren zur herstellung von neuen d-homosteroiden
CS7600005074A CS179948B2 (en) 1973-03-28 1974-09-25 Method for production of novel d-homopregn-4-ene3,20-diones
ES430370A ES430370A1 (es) 1973-03-28 1974-09-25 Un procedimiento para la preparacion de de-homoesteroides.
PL1974182344A PL95271B1 (pl) 1973-03-28 1974-09-25 Sposob wytwarzania nowych d-homosteroidow
DE2445817A DE2445817C2 (de) 1973-03-28 1974-09-25 D-Homosteroide und diese enthaltende Präparate
CS7400006584A CS179927B2 (en) 1973-03-28 1974-09-25 Method for production of novel d-homopregn-4ene-3,20-diones
BE148858A BE820304A (fr) 1973-03-28 1974-09-25 Nouveaux steroides
CS7600005075A CS179949B2 (en) 1973-03-28 1974-09-25 Method for production of novel d-homopregn-4-ene 3,20-diones
SU752145928A SU683630A3 (ru) 1973-03-28 1975-06-20 Способ получени -гомостероидов
SU752145930A SU634676A3 (ru) 1973-03-28 1975-06-20 Способ получени -гомостероидов
SU752145940A SU635875A3 (ru) 1973-03-28 1975-06-20 Способ получени -гомостероидов
SU752145938A SU867316A3 (ru) 1973-03-28 1975-06-20 Способ получени д-гомостероидов
SU752145939A SU612638A3 (ru) 1973-03-28 1975-06-20 Способ получени -гомостероидов
SU7502145936A SU564814A3 (ru) 1973-03-28 1975-06-20 Способ получени -гомостероидов
AR259890A AR211000A1 (es) 1973-03-28 1975-08-04 Procedimiento para la preparacion de derivados de d-homo-pregn -4-en -3, 20 dionas que tienen util actividad endocrina, especialmente anti-inflamatoria.
US05/629,439 US4026923A (en) 1973-03-28 1975-11-06 D-Homosteroids
AT561376A AT348165B (de) 1973-03-28 1976-07-29 Verfahren zur herstellung von neuen d- homosteroiden
AT561476A AT346507B (de) 1973-03-28 1976-07-29 Verfahren zur herstellung von neuen d- homosteroiden
ES455100A ES455100A1 (es) 1973-03-28 1977-01-17 Un procedimiento para la preparacion de d-homoesteroides.
ES455101A ES455101A1 (es) 1973-03-28 1977-01-17 Un procedimiento para la preparacion de d-homoesteroides.
ES455105A ES455105A1 (es) 1973-03-28 1977-01-17 Un procedimiento para la preparacion de d-homoesteroides.
ES455103A ES455103A1 (es) 1973-03-28 1977-01-17 Un procedimiento para la preparacion de d-homoesteroides.
ES455106A ES455106A1 (es) 1973-03-28 1977-01-17 Un procedimiento para la preparacion de d-homoesteroides.
ES455107A ES455107A1 (es) 1973-03-28 1977-01-17 Un procedimiento para la preparacion de d-homoesteroides.
ES455104A ES455104A1 (es) 1973-03-28 1977-01-17 Un procedimiento para la preparacion de d-homoesteroides.
ES455102A ES455102A1 (es) 1973-03-28 1977-01-17 Un procedimiento para la preparacion e d-homoesteroides.
YU2966/80A YU36979B (en) 1973-03-28 1980-11-21 Process for obtaining new d-homosteroids
YU2967/80A YU36980B (en) 1973-03-28 1980-11-21 Process for obtaining new d-homosteroids
JP57147864A JPS596880B2 (ja) 1973-03-28 1982-08-27 Ｄ−ホモステロイドの製造方法
JP57147865A JPS5928560B2 (ja) 1973-03-28 1982-08-27 Ｄ−ホモステロイドの製造方法

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DK170673 1973-03-28
DK170673AA DK135722B (da) 1972-03-29 1973-03-28 Analogifremgangsmåde til fremstilling af 11beta,17aalfa,21-trihydroxy-D-homopregn-4-en-3,20-dioner.
CH1376473A CH596237A5 (en) 1973-09-26 1973-09-26 9-Alpha-11-beta-dihalo-D-homo-pregn-4-en-3,20-diones
CH1376473 1973-09-26
DK531173 1973-09-28
DK531173AA DK142289B (da) 1973-03-28 1973-09-28 Analogifremgangsmåde til fremstilling af D-homopregn-4-en-3,20-dioner.

Publications (3)

Publication Number Publication Date
DK531173A DK531173A (pl) 1975-06-23
DK142289B true DK142289B (da) 1980-10-06
DK142289C DK142289C (pl) 1981-02-23

Family

ID=27177053

Family Applications (1)

Application Number Title Priority Date Filing Date
DK531173AA DK142289B (da) 1973-03-28 1973-09-28 Analogifremgangsmåde til fremstilling af D-homopregn-4-en-3,20-dioner.

Country Status (26)

Country Link
US (1) US3939193A (pl)
JP (3) JPS595600B2 (pl)
AR (1) AR211000A1 (pl)
AT (1) AT335087B (pl)
BE (1) BE820304A (pl)
CA (1) CA1031323A (pl)
CS (4) CS179950B2 (pl)
DD (1) DD115354A5 (pl)
DE (1) DE2445817C2 (pl)
DK (1) DK142289B (pl)
EG (1) EG11212A (pl)
ES (9) ES430370A1 (pl)
FI (1) FI54604C (pl)
FR (1) FR2244474B1 (pl)
GB (1) GB1445945A (pl)
HU (1) HU172657B (pl)
IE (1) IE40178B1 (pl)
IL (1) IL45516A (pl)
LU (1) LU70979A1 (pl)
NO (1) NO140672C (pl)
PH (1) PH11410A (pl)
PL (5) PL95273B1 (pl)
SE (1) SE418402B (pl)
SU (6) SU867316A3 (pl)
YU (3) YU36745B (pl)
ZA (1) ZA745316B (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4036874A (en) * 1972-03-29 1977-07-19 Hoffmann-La Roche Inc. D-homopregnanes
US4026923A (en) * 1973-03-28 1977-05-31 Hoffmann-La Roche Inc. D-Homosteroids
DE2349022A1 (de) * 1973-09-26 1975-04-10 Schering Ag Neue d-homo-steroide
DE2349023A1 (de) * 1973-09-26 1975-04-10 Schering Ag Neue d-homo-steroide
SE427276B (sv) * 1975-04-03 1983-03-21 Hoffmann La Roche Forfarande for framstellning av d-homosteroider
US4139716A (en) * 1975-04-09 1979-02-13 Hoffmann-La Roche Inc. 19-Nor-D-homopregnanes
DE2526372C2 (de) * 1975-06-11 1983-12-08 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von Δ↑9↑↑(↑↑1↑↑1↑↑)↑-5α-D-Homo-20-ketosteroiden
NL7611162A (nl) * 1975-10-22 1977-04-26 Hoffmann La Roche Nieuwe d-homosteroiden.
AT356301B (de) * 1976-09-03 1980-04-25 Hoffmann La Roche Verfahren zur herstellung von neuen d-homo- steroiden
NL7802905A (nl) * 1977-04-21 1978-10-24 Hoffmann La Roche Werkwijze voor het bereiden van d-homosteroiden.
US4202841A (en) * 1977-08-25 1980-05-13 Hoffmann-La Roche Inc. D-Homopregnanes
DE3038855A1 (de) * 1980-10-10 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue d-homo-kortikoide, ihre herstellung und verwendung
JPS59181878U (ja) * 1983-05-24 1984-12-04 東芝機械株式会社 半導体結晶引上機用シ−ドホルダ連結金具
DE3409554A1 (de) * 1984-03-13 1985-09-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6(alpha)-methyl-d-homo-kortikoide
JPS61115907U (pl) * 1984-12-30 1986-07-22
CN106831920B (zh) * 2016-12-03 2019-03-05 丽江映华生物药业有限公司 一种合成6-亚甲基-17α-羟基-19-去甲孕甾-4-烯-3,20-二酮的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2860158A (en) * 1954-10-18 1958-11-11 Sterling Drug Inc Compounds of the perhydrochrysene series and preparation thereof
US3686223A (en) * 1968-12-26 1972-08-22 Sterling Drug Inc D-homoestratrienes
US3833621A (en) * 1972-03-20 1974-09-03 Richardson Merrell Inc 3-keto-7(alpha,beta)-loweralkyl-delta5 steroids and process for preparing same
CH571018A5 (pl) * 1972-03-29 1975-12-31 Hoffmann La Roche

Also Published As

Publication number Publication date
JPS5928560B2 (ja) 1984-07-13
JPS5058052A (pl) 1975-05-20
SE7313269L (pl) 1975-03-27
ES455104A1 (es) 1977-12-16
PL95291B1 (pl) 1977-10-31
YU243074A (en) 1982-06-18
IE40178B1 (en) 1979-03-28
ZA745316B (en) 1975-08-27
FI54604B (fi) 1978-09-29
SE418402B (sv) 1981-05-25
CA1031323A (en) 1978-05-16
FR2244474A1 (pl) 1975-04-18
YU296680A (en) 1982-06-18
ATA771974A (de) 1976-06-15
LU70979A1 (pl) 1976-08-19
IE40178L (en) 1975-03-26
SU683630A3 (ru) 1979-08-30
ES455106A1 (es) 1978-01-01
NO140672C (no) 1979-10-17
SU634676A3 (ru) 1978-11-25
DE2445817C2 (de) 1985-09-05
NO140672B (no) 1979-07-09
DD115354A5 (pl) 1975-09-20
JPS5844000A (ja) 1983-03-14
DK142289C (pl) 1981-02-23
CS179950B2 (en) 1977-12-30
YU36745B (en) 1984-08-31
FI54604C (fi) 1979-01-10
ES430370A1 (es) 1977-06-01
SU612638A3 (ru) 1978-06-25
PL95273B1 (pl) 1977-10-31
AT335087B (de) 1977-02-25
PL95272B1 (pl) 1977-10-31
AR211000A1 (es) 1977-10-14
DK531173A (pl) 1975-06-23
ES455100A1 (es) 1977-12-16
ES455107A1 (es) 1977-12-16
CS179948B2 (en) 1977-12-30
ES455105A1 (es) 1977-12-16
IL45516A0 (en) 1974-12-31
BE820304A (fr) 1975-03-25
CS179949B2 (en) 1977-12-30
FI276774A (pl) 1975-03-27
EG11212A (en) 1977-01-31
NO380073L (pl) 1975-04-28
ES455103A1 (es) 1977-12-16
PL95270B1 (pl) 1977-10-31
FR2244474B1 (pl) 1978-06-30
PL95271B1 (pl) 1977-10-31
YU36979B (en) 1984-08-31
JPS5843999A (ja) 1983-03-14
SU635875A3 (ru) 1978-11-30
CS179927B2 (en) 1977-12-30
JPS595600B2 (ja) 1984-02-06
AU7263374A (en) 1976-02-26
IL45516A (en) 1978-03-10
PH11410A (en) 1977-12-27
ES455102A1 (es) 1978-01-01
DE2445817A1 (de) 1975-04-03
HU172657B (hu) 1978-11-28
SU867316A3 (ru) 1981-09-23
GB1445945A (en) 1976-08-11
YU36980B (en) 1984-08-31
ES455101A1 (es) 1977-12-16
SU564814A3 (ru) 1977-07-05
US3939193A (en) 1976-02-17
JPS596880B2 (ja) 1984-02-15
YU296780A (en) 1982-06-18

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