DK1235832T3 - Precursorer for vitamin D, fremgangsmåde til fremstilling heraf og mellemforbindelser - Google Patents
Precursorer for vitamin D, fremgangsmåde til fremstilling heraf og mellemforbindelserInfo
- Publication number
- DK1235832T3 DK1235832T3 DK00983224T DK00983224T DK1235832T3 DK 1235832 T3 DK1235832 T3 DK 1235832T3 DK 00983224 T DK00983224 T DK 00983224T DK 00983224 T DK00983224 T DK 00983224T DK 1235832 T3 DK1235832 T3 DK 1235832T3
- Authority
- DK
- Denmark
- Prior art keywords
- intermediates
- precursors
- vitamin
- preparation
- processes
- Prior art date
Links
- 229930003316 Vitamin D Natural products 0.000 title abstract 2
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title abstract 2
- 239000002243 precursor Substances 0.000 title abstract 2
- 235000019166 vitamin D Nutrition 0.000 title abstract 2
- 239000011710 vitamin D Substances 0.000 title abstract 2
- 150000003710 vitamin D derivatives Chemical class 0.000 title abstract 2
- 229940046008 vitamin d Drugs 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- UYEMGAFJOZZIFP-UHFFFAOYSA-N 3,5-dihydroxybenzoic acid Chemical class OC(=O)C1=CC(O)=CC(O)=C1 UYEMGAFJOZZIFP-UHFFFAOYSA-N 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
- C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/78—Benzoic acid esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/40—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing six carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99403065A EP1106618A1 (en) | 1999-12-08 | 1999-12-08 | Precursors of the A-ring of vitamin D, and method and intermediates for the preparation thereof |
| US09/456,509 US6191292B1 (en) | 1999-12-08 | 1999-12-08 | Precursors of the A-ring of vitamin D and method and intermediates for the preparation thereof |
| PCT/EP2000/012225 WO2001042251A1 (en) | 1999-12-08 | 2000-12-04 | Vitamin d precursors, method and intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1235832T3 true DK1235832T3 (da) | 2004-03-22 |
Family
ID=26153704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00983224T DK1235832T3 (da) | 1999-12-08 | 2000-12-04 | Precursorer for vitamin D, fremgangsmåde til fremstilling heraf og mellemforbindelser |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6191292B1 (pt) |
| EP (2) | EP1106618A1 (pt) |
| CN (1) | CN1210282C (pt) |
| AT (1) | ATE254623T1 (pt) |
| AU (1) | AU782089B2 (pt) |
| BR (1) | BRPI0016184B8 (pt) |
| CA (1) | CA2393617C (pt) |
| CZ (1) | CZ303421B6 (pt) |
| DE (1) | DE60006714T2 (pt) |
| DK (1) | DK1235832T3 (pt) |
| EE (1) | EE05326B1 (pt) |
| ES (1) | ES2210022T3 (pt) |
| HU (1) | HU229508B1 (pt) |
| IL (1) | IL150089A0 (pt) |
| MX (1) | MXPA01012904A (pt) |
| NO (1) | NO327848B1 (pt) |
| NZ (1) | NZ519391A (pt) |
| PL (1) | PL201691B1 (pt) |
| PT (1) | PT1235832E (pt) |
| RU (1) | RU2247710C2 (pt) |
| TW (1) | TWI290928B (pt) |
| WO (1) | WO2001042251A1 (pt) |
| ZA (1) | ZA200204594B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2360145E (pt) | 2010-01-26 | 2012-06-27 | Hybrigenics Sa | Novo processo para isomerização de estruturas bicíclicas condensadas e preparação de análogos de vitamina d que as contêm |
| EP2793622B1 (de) | 2011-12-21 | 2019-02-27 | Merck Patent GmbH | Verwendung von cyclohexanolderivaten als antimikrobielle wirkstoffe |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2147238T3 (es) * | 1993-07-09 | 2000-09-01 | Theramex | Nuevos analogos estructurales de la vitamina d. |
-
1999
- 1999-12-08 US US09/456,509 patent/US6191292B1/en not_active Expired - Lifetime
- 1999-12-08 EP EP99403065A patent/EP1106618A1/en not_active Withdrawn
-
2000
- 2000-10-30 TW TW089122845A patent/TWI290928B/zh not_active IP Right Cessation
- 2000-12-04 CZ CZ20021977A patent/CZ303421B6/cs not_active IP Right Cessation
- 2000-12-04 PL PL356389A patent/PL201691B1/pl unknown
- 2000-12-04 MX MXPA01012904A patent/MXPA01012904A/es active IP Right Grant
- 2000-12-04 IL IL15008900A patent/IL150089A0/xx active IP Right Grant
- 2000-12-04 BR BRPI0016184A patent/BRPI0016184B8/pt not_active IP Right Cessation
- 2000-12-04 DE DE60006714T patent/DE60006714T2/de not_active Expired - Lifetime
- 2000-12-04 CA CA2393617A patent/CA2393617C/en not_active Expired - Lifetime
- 2000-12-04 AU AU20051/01A patent/AU782089B2/en not_active Expired
- 2000-12-04 EE EEP200200294A patent/EE05326B1/xx unknown
- 2000-12-04 RU RU2002118103/04A patent/RU2247710C2/ru active
- 2000-12-04 WO PCT/EP2000/012225 patent/WO2001042251A1/en active IP Right Grant
- 2000-12-04 CN CNB008184984A patent/CN1210282C/zh not_active Expired - Lifetime
- 2000-12-04 DK DK00983224T patent/DK1235832T3/da active
- 2000-12-04 PT PT00983224T patent/PT1235832E/pt unknown
- 2000-12-04 HU HU0204521A patent/HU229508B1/hu unknown
- 2000-12-04 AT AT00983224T patent/ATE254623T1/de active
- 2000-12-04 EP EP00983224A patent/EP1235832B1/en not_active Expired - Lifetime
- 2000-12-04 ES ES00983224T patent/ES2210022T3/es not_active Expired - Lifetime
- 2000-12-04 NZ NZ519391A patent/NZ519391A/en not_active IP Right Cessation
-
2002
- 2002-06-06 NO NO20022690A patent/NO327848B1/no not_active IP Right Cessation
- 2002-06-07 ZA ZA200204594A patent/ZA200204594B/xx unknown
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