ATE254623T1 - Vitamin-d-vorlaüferverbindungen, verfahren und intermediären zu deren herstellung - Google Patents

Vitamin-d-vorlaüferverbindungen, verfahren und intermediären zu deren herstellung

Info

Publication number
ATE254623T1
ATE254623T1 AT00983224T AT00983224T ATE254623T1 AT E254623 T1 ATE254623 T1 AT E254623T1 AT 00983224 T AT00983224 T AT 00983224T AT 00983224 T AT00983224 T AT 00983224T AT E254623 T1 ATE254623 T1 AT E254623T1
Authority
AT
Austria
Prior art keywords
vitamin
intermediaries
production
methods
precursor compounds
Prior art date
Application number
AT00983224T
Other languages
English (en)
Inventor
Jean-Claude Pascal
Maurits Vandewalle
Philippe Maillos
Clercq Pierre De
Original Assignee
Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theramex filed Critical Theramex
Application granted granted Critical
Publication of ATE254623T1 publication Critical patent/ATE254623T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/78—Benzoic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/40—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing six carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cephalosporin Compounds (AREA)
AT00983224T 1999-12-08 2000-12-04 Vitamin-d-vorlaüferverbindungen, verfahren und intermediären zu deren herstellung ATE254623T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99403065A EP1106618A1 (de) 1999-12-08 1999-12-08 Vorläuferverbindungen für den A-Ring von Vitamin-D, Verfahren zur Herstellung und Zwischenprodukte dazu
US09/456,509 US6191292B1 (en) 1999-12-08 1999-12-08 Precursors of the A-ring of vitamin D and method and intermediates for the preparation thereof
PCT/EP2000/012225 WO2001042251A1 (en) 1999-12-08 2000-12-04 Vitamin d precursors, method and intermediates

Publications (1)

Publication Number Publication Date
ATE254623T1 true ATE254623T1 (de) 2003-12-15

Family

ID=26153704

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00983224T ATE254623T1 (de) 1999-12-08 2000-12-04 Vitamin-d-vorlaüferverbindungen, verfahren und intermediären zu deren herstellung

Country Status (23)

Country Link
US (1) US6191292B1 (de)
EP (2) EP1106618A1 (de)
CN (1) CN1210282C (de)
AT (1) ATE254623T1 (de)
AU (1) AU782089B2 (de)
BR (1) BRPI0016184B8 (de)
CA (1) CA2393617C (de)
CZ (1) CZ303421B6 (de)
DE (1) DE60006714T2 (de)
DK (1) DK1235832T3 (de)
EE (1) EE05326B1 (de)
ES (1) ES2210022T3 (de)
HU (1) HU229508B1 (de)
IL (1) IL150089A0 (de)
MX (1) MXPA01012904A (de)
NO (1) NO327848B1 (de)
NZ (1) NZ519391A (de)
PL (1) PL201691B1 (de)
PT (1) PT1235832E (de)
RU (1) RU2247710C2 (de)
TW (1) TWI290928B (de)
WO (1) WO2001042251A1 (de)
ZA (1) ZA200204594B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2360145T3 (pl) 2010-01-26 2012-08-31 Hybrigenics Sa Nowy sposób izomeryzacji skondensowanych struktur bicyklicznych oraz wytwarzania zawierających te struktury analogów witaminy D
RU2642987C2 (ru) 2011-12-21 2018-01-29 Мерк Патент Гмбх Применение производных циклогексанола в качестве антимикробных активных соединений

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2166898C (en) 1993-07-09 2004-09-07 Roger Bouillon Novel structural analogues of vitamin d

Also Published As

Publication number Publication date
WO2001042251A1 (en) 2001-06-14
EE05326B1 (et) 2010-08-16
US6191292B1 (en) 2001-02-20
EP1235832B1 (de) 2003-11-19
AU2005101A (en) 2001-06-18
EP1235832A1 (de) 2002-09-04
BRPI0016184B8 (pt) 2021-05-25
HUP0204521A3 (en) 2005-03-29
CZ20021977A3 (cs) 2002-10-16
DE60006714D1 (de) 2003-12-24
CA2393617C (en) 2010-03-23
PL201691B1 (pl) 2009-04-30
CN1210282C (zh) 2005-07-13
DK1235832T3 (da) 2004-03-22
RU2247710C2 (ru) 2005-03-10
NZ519391A (en) 2003-08-29
TWI290928B (en) 2007-12-11
NO20022690D0 (no) 2002-06-06
DE60006714T2 (de) 2004-12-02
CZ303421B6 (cs) 2012-09-05
CN1425019A (zh) 2003-06-18
NO327848B1 (no) 2009-10-05
NO20022690L (no) 2002-06-06
ES2210022T3 (es) 2004-07-01
EE200200294A (et) 2003-08-15
BR0016184A (pt) 2002-08-20
ZA200204594B (en) 2003-10-29
IL150089A0 (en) 2002-12-01
EP1106618A1 (de) 2001-06-13
PL356389A1 (en) 2004-06-28
CA2393617A1 (en) 2001-06-14
MXPA01012904A (es) 2002-11-07
BRPI0016184B1 (pt) 2015-07-14
HU229508B1 (en) 2014-01-28
HUP0204521A2 (en) 2003-05-28
AU782089B2 (en) 2005-06-30
PT1235832E (pt) 2004-04-30

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