DK1155034T3 - Dannelse og anionbytning af indre krystallinske echinocandin B-ammoniumsalte - Google Patents

Dannelse og anionbytning af indre krystallinske echinocandin B-ammoniumsalte

Info

Publication number
DK1155034T3
DK1155034T3 DK00916011T DK00916011T DK1155034T3 DK 1155034 T3 DK1155034 T3 DK 1155034T3 DK 00916011 T DK00916011 T DK 00916011T DK 00916011 T DK00916011 T DK 00916011T DK 1155034 T3 DK1155034 T3 DK 1155034T3
Authority
DK
Denmark
Prior art keywords
formation
ammonium salts
anion exchange
salt
echinocandin
Prior art date
Application number
DK00916011T
Other languages
Danish (da)
English (en)
Inventor
Brian Weston Dalder
Jeffrey Thomas Vicenzi
Michael Anthony Dotlich
Neil John Kallman
Samuel Dean Larsen
Den Berghe Snorek Sharon Van
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK1155034T3 publication Critical patent/DK1155034T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/895—Manufacture, treatment, or detection of nanostructure having step or means utilizing chemical property
    • Y10S977/896—Chemical synthesis, e.g. chemical bonding or breaking
    • Y10S977/898—Enzymatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK00916011T 1999-03-03 2000-03-02 Dannelse og anionbytning af indre krystallinske echinocandin B-ammoniumsalte DK1155034T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12307399P 1999-03-03 1999-03-03

Publications (1)

Publication Number Publication Date
DK1155034T3 true DK1155034T3 (da) 2007-01-08

Family

ID=22406562

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00916011T DK1155034T3 (da) 1999-03-03 2000-03-02 Dannelse og anionbytning af indre krystallinske echinocandin B-ammoniumsalte

Country Status (18)

Country Link
US (1) US6590073B2 (https=)
EP (1) EP1155034B1 (https=)
JP (1) JP4063497B2 (https=)
KR (1) KR20020002476A (https=)
CN (1) CN1351610A (https=)
AT (1) ATE338060T1 (https=)
AU (1) AU767956B2 (https=)
BR (1) BR0009248A (https=)
CA (1) CA2362826A1 (https=)
CY (1) CY1105777T1 (https=)
DE (1) DE60030415T2 (https=)
DK (1) DK1155034T3 (https=)
ES (1) ES2270819T3 (https=)
HK (1) HK1040087A1 (https=)
IL (1) IL145186A0 (https=)
PT (1) PT1155034E (https=)
WO (1) WO2000052036A1 (https=)
ZA (1) ZA200107999B (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
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US6743777B1 (en) * 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
DE69933046T2 (de) 1998-12-09 2007-09-13 Eli Lilly And Co., Indianapolis Reinigung von echinocandin cyclopeptiden
KR20020003864A (ko) 1999-03-03 2002-01-15 피터 지. 스트링거 에키노칸딘/탄수화물 착물
EP1582204B1 (en) 1999-03-03 2013-09-25 Eli Lilly & Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
AU767956B2 (en) 1999-03-03 2003-11-27 Eli Lilly And Company Formation and anion-exchange of crystalline echinocandin ammonium salts
WO2000051567A1 (en) 1999-03-03 2000-09-08 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
TW200826957A (en) 2006-10-16 2008-07-01 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Purification processes for echinocandin-type compounds
EP2062909A1 (en) * 2007-11-21 2009-05-27 SOLVAY (Société Anonyme) Peptide production and purification process
US9394340B2 (en) 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides
WO2010108637A1 (en) * 2009-03-27 2010-09-30 Axellia Pharmaceuticals Aps Crystalline compound
CN102464704B (zh) * 2010-11-05 2013-12-11 上海医药工业研究院 一种化合物及其制备方法和用途
CN102485879A (zh) * 2010-12-03 2012-06-06 上海医药工业研究院 一种用于生产wf11899a的发酵培养基
CN102295686A (zh) * 2011-09-09 2011-12-28 杭州华东医药集团生物工程研究所有限公司 一种纽莫康定b0的提取纯化方法
CN102627688B (zh) * 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN102659930B (zh) * 2012-03-30 2014-04-23 上海天伟生物制药有限公司 一种高纯度环肽类物质的晶体及其制备方法和用途
CN105669840B (zh) * 2014-12-05 2019-06-04 重庆乾泰生物医药有限公司 一种高纯度棘白菌素b母核盐酸盐的晶体及其制备方法
CN110128507A (zh) * 2014-12-05 2019-08-16 重庆乾泰生物医药有限公司 一种棘白菌素b母核或其盐的水合物及制备方法和用途
WO2020086931A1 (en) * 2018-10-25 2020-04-30 Cidara Therapeutics, Inc. Polymorph of echinocandin antifungal agent

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JPS5134916B2 (https=) 1974-03-06 1976-09-29
CA1170598A (en) * 1979-12-13 1984-07-10 Bernard J. Abbott Process for the preparation of cyclic peptide nuclei
US4320052A (en) 1979-12-13 1982-03-16 Eli Lilly And Company Derivatives of A-30912A nucleus
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US4299763A (en) 1979-12-13 1981-11-10 Eli Lilly And Company A-30912B Nucleus
US4293483A (en) 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
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US5166135A (en) 1988-09-12 1992-11-24 Merck & Company, Inc. Method for the control of pneumocystis carinii
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US5310726A (en) 1990-03-19 1994-05-10 Merck & Co., Inc. Lipopeptide compounds
ES2089133T3 (es) 1990-06-07 1996-10-01 Lilly Co Eli Desacilasa de lipopeptidos.
IE990233A1 (en) 1990-06-18 2000-11-15 Fujisawa Pharmaceutical Co New Polypeptide Compound and a Process for Preparation thereof
US5198421A (en) 1991-04-26 1993-03-30 Merck & Co., Inc. Phosphorylated cyclic lipopeptide
US5965525A (en) 1992-03-19 1999-10-12 Eli Lilly And Company Cyclic peptide antifungal agents
NZ247149A (en) 1992-03-19 1996-10-28 Lilly Co Eli Cyclic peptide antifungal agents and compositions thereof
US5541160A (en) 1994-04-04 1996-07-30 Merck & Co., Inc. Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use
US5646111A (en) 1995-04-07 1997-07-08 Eli Lilly And Company Cyclic peptide antifungal Agents
US5618787A (en) 1995-05-26 1997-04-08 Eli Lilly And Company Cyclic peptide antifungal agents
US5786325A (en) 1995-05-26 1998-07-28 Eli Lilly And Company Cyclic peptide antifungal agents and methods of making and using
US5652213A (en) 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
US5629290A (en) 1995-05-26 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5629289A (en) 1995-07-25 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
WO1997027864A1 (en) * 1996-02-01 1997-08-07 Eli Lilly And Company Cyclic peptide antifungal agents
JPH1036284A (ja) * 1996-07-24 1998-02-10 Sumitomo Pharmaceut Co Ltd プロテアソーム阻害剤
WO1999006062A1 (en) 1997-08-04 1999-02-11 Eli Lilly And Company Cyclic peptide antifungal agents
JP3561917B2 (ja) * 1998-02-09 2004-09-08 藤沢薬品工業株式会社 新規化合物
US6323176B1 (en) 1998-02-25 2001-11-27 Eli Lilly And Company Cyclic peptide antifungal agents
ES2233070T3 (es) 1998-08-20 2005-06-01 ELI LILLY & COMPANY Sintesis de analogos peptidicos ciclicos modificados en el anillo.
WO2000012540A1 (en) 1998-08-28 2000-03-09 Eli Lilly And Company Reversible boronate complexes of 1,2-cis-diol cyclic-peptides
DE69933046T2 (de) 1998-12-09 2007-09-13 Eli Lilly And Co., Indianapolis Reinigung von echinocandin cyclopeptiden
JP2002532513A (ja) 1998-12-16 2002-10-02 イーライ リリー アンド カンパニー 糖置換基を有する環式ペプチド抗真菌剤
AU767357B2 (en) 1998-12-16 2003-11-06 Eli Lilly And Company Cyclic peptide antifungal agents
KR20020003864A (ko) 1999-03-03 2002-01-15 피터 지. 스트링거 에키노칸딘/탄수화물 착물
AU767956B2 (en) 1999-03-03 2003-11-27 Eli Lilly And Company Formation and anion-exchange of crystalline echinocandin ammonium salts
WO2000051567A1 (en) 1999-03-03 2000-09-08 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions
EP1582204B1 (en) 1999-03-03 2013-09-25 Eli Lilly & Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants

Also Published As

Publication number Publication date
AU3718200A (en) 2000-09-21
DE60030415D1 (de) 2006-10-12
BR0009248A (pt) 2001-11-20
JP4063497B2 (ja) 2008-03-19
AU767956B2 (en) 2003-11-27
EP1155034A1 (en) 2001-11-21
US6590073B2 (en) 2003-07-08
CY1105777T1 (el) 2011-02-02
ATE338060T1 (de) 2006-09-15
KR20020002476A (ko) 2002-01-09
HK1040087A1 (zh) 2002-05-24
ZA200107999B (en) 2003-06-25
IL145186A0 (en) 2002-06-30
PT1155034E (pt) 2007-01-31
CN1351610A (zh) 2002-05-29
JP2002538165A (ja) 2002-11-12
WO2000052036A8 (en) 2001-06-21
US20020161176A1 (en) 2002-10-31
WO2000052036A1 (en) 2000-09-08
ES2270819T3 (es) 2007-04-16
EP1155034B1 (en) 2006-08-30
DE60030415T2 (de) 2007-08-30
CA2362826A1 (en) 2000-09-08

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