PT1581504E - Processo de preparação de derivados de imidazole substituídos e intermediários utilizados no processo - Google Patents

Processo de preparação de derivados de imidazole substituídos e intermediários utilizados no processo Download PDF

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Publication number
PT1581504E
PT1581504E PT04700707T PT04700707T PT1581504E PT 1581504 E PT1581504 E PT 1581504E PT 04700707 T PT04700707 T PT 04700707T PT 04700707 T PT04700707 T PT 04700707T PT 1581504 E PT1581504 E PT 1581504E
Authority
PT
Portugal
Prior art keywords
sub
imidazole derivatives
substituted imidazole
preparing substituted
intermediates used
Prior art date
Application number
PT04700707T
Other languages
English (en)
Inventor
Paeivi Juujaervi
Seppo Parhi
Jaana Karjalainen
Original Assignee
Juvantia Pharma Ltd Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Juvantia Pharma Ltd Oy filed Critical Juvantia Pharma Ltd Oy
Publication of PT1581504E publication Critical patent/PT1581504E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PT04700707T 2003-01-08 2004-01-08 Processo de preparação de derivados de imidazole substituídos e intermediários utilizados no processo PT1581504E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20030026A FI116292B (fi) 2003-01-08 2003-01-08 Menetelmä substituoitujen imidatsolijohdannaisten valmistamiseksi ja menetelmässä käytettäviä välituotteita

Publications (1)

Publication Number Publication Date
PT1581504E true PT1581504E (pt) 2009-05-26

Family

ID=8565279

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04700707T PT1581504E (pt) 2003-01-08 2004-01-08 Processo de preparação de derivados de imidazole substituídos e intermediários utilizados no processo

Country Status (21)

Country Link
US (1) US7223871B2 (pt)
EP (1) EP1581504B1 (pt)
JP (1) JP4592680B2 (pt)
KR (1) KR101079065B1 (pt)
CN (1) CN100339368C (pt)
AT (1) ATE425972T1 (pt)
AU (1) AU2004203941B2 (pt)
BR (1) BRPI0406676A (pt)
CA (1) CA2511969C (pt)
DE (1) DE602004020050D1 (pt)
DK (1) DK1581504T3 (pt)
ES (1) ES2322463T3 (pt)
FI (1) FI116292B (pt)
IL (1) IL168452A (pt)
MX (1) MXPA05007217A (pt)
NO (1) NO330965B1 (pt)
NZ (1) NZ539831A (pt)
PL (1) PL213564B1 (pt)
PT (1) PT1581504E (pt)
RU (1) RU2329253C2 (pt)
WO (1) WO2004063168A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2008003553A1 (es) * 2007-12-05 2009-11-27 Grindeks Jsc Proceso para preparar atipamezol o clorhidrato de 5-(2-etil-2,3-dihidro-1h-inden-2-il)-1h-imidazol: y loa compuestos intermediarios considerados en el proceso
EP2456749B1 (en) 2009-07-24 2016-03-30 DSM Pharma Chemicals Regensburg GmbH Indane derivatives for use as intermediates
WO2011014613A2 (en) * 2009-07-31 2011-02-03 Dr. Reddy's Laboratories Ltd. Preparation of fipamezole
EP2502917A1 (en) * 2011-03-17 2012-09-26 Santhera Pharmaceuticals (Schweiz) AG Solid state crystalline forms of 4-(2-ethyl-5-fluoro-2,3-dihydro-1H-inden-2-yl)-1H-imidazole

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI833794A0 (fi) 1983-10-18 1983-10-18 Farmos Oy Substituerade 2-merkapto-imidazoler
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use
JP2003508521A (ja) 1999-09-06 2003-03-04 エルジー シーアイ リミテッド １位で置換された５−ヒドロキシメチルイミダゾールの製造方法
US7091232B2 (en) * 2002-05-21 2006-08-15 Allergan, Inc. 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds

Also Published As

Publication number Publication date
AU2004203941A1 (en) 2004-07-29
BRPI0406676A (pt) 2005-12-20
EP1581504B1 (en) 2009-03-18
US7223871B2 (en) 2007-05-29
ES2322463T3 (es) 2009-06-22
RU2329253C2 (ru) 2008-07-20
CA2511969C (en) 2011-10-11
DE602004020050D1 (de) 2009-04-30
CA2511969A1 (en) 2004-07-29
US20060025465A1 (en) 2006-02-02
JP4592680B2 (ja) 2010-12-01
NZ539831A (en) 2007-11-30
NO20053712L (no) 2005-08-01
RU2005125044A (ru) 2006-01-20
CN1723202A (zh) 2006-01-18
CN100339368C (zh) 2007-09-26
FI116292B (fi) 2005-10-31
EP1581504A1 (en) 2005-10-05
KR101079065B1 (ko) 2011-11-02
AU2004203941B2 (en) 2009-08-06
IL168452A (en) 2009-07-20
JP2006515349A (ja) 2006-05-25
KR20050091065A (ko) 2005-09-14
PL378179A1 (pl) 2006-03-06
MXPA05007217A (es) 2005-09-12
WO2004063168A1 (en) 2004-07-29
PL213564B1 (pl) 2013-03-29
ATE425972T1 (de) 2009-04-15
DK1581504T3 (da) 2009-06-29
NO330965B1 (no) 2011-08-29
FI20030026A0 (fi) 2003-01-08
FI20030026A (fi) 2004-07-09

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