BRPI0406676A - Processo para preparar derivados de imidazol substituìdo, para preparar um composto e composto resultante - Google Patents
Processo para preparar derivados de imidazol substituìdo, para preparar um composto e composto resultanteInfo
- Publication number
- BRPI0406676A BRPI0406676A BR0406676-6A BRPI0406676A BRPI0406676A BR PI0406676 A BRPI0406676 A BR PI0406676A BR PI0406676 A BRPI0406676 A BR PI0406676A BR PI0406676 A BRPI0406676 A BR PI0406676A
- Authority
- BR
- Brazil
- Prior art keywords
- sub
- compound
- imidazole derivatives
- prepare
- substituted imidazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
"PROCESSO PARA PREPARAR DERIVADOS DE IMIDAZOL SUBSTITUìDO, PARA PREPARAR UM COMPOSTO E COMPOSTO RESULTANTE". A invenção refere-se a um processo para preparar derivados de imidazol substituído da fórmula e seus sais de adição ácida (I), fórmula essa em que Y é -CH~ 2~ ou -CO-, R~ 1~ é H, halo ou hidroxila, R~ 2~ é H ou halo e R~ 3~ é H ou alquila inferior, partindo-se de um composto da fórmula (II) em que Y, R~ 1~, R~ 2~ e R~ 3~ são tais como definidos anteriormente. A invenção também se refere a intermediários e à sua preparação.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20030026A FI116292B (fi) | 2003-01-08 | 2003-01-08 | Menetelmä substituoitujen imidatsolijohdannaisten valmistamiseksi ja menetelmässä käytettäviä välituotteita |
| PCT/FI2004/000004 WO2004063168A1 (en) | 2003-01-08 | 2004-01-08 | Process for preparing substituted imidazole derivatives and intermediates used in the process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0406676A true BRPI0406676A (pt) | 2005-12-20 |
Family
ID=8565279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0406676-6A BRPI0406676A (pt) | 2003-01-08 | 2004-01-08 | Processo para preparar derivados de imidazol substituìdo, para preparar um composto e composto resultante |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7223871B2 (pt) |
| EP (1) | EP1581504B1 (pt) |
| JP (1) | JP4592680B2 (pt) |
| KR (1) | KR101079065B1 (pt) |
| CN (1) | CN100339368C (pt) |
| AT (1) | ATE425972T1 (pt) |
| AU (1) | AU2004203941B2 (pt) |
| BR (1) | BRPI0406676A (pt) |
| CA (1) | CA2511969C (pt) |
| DE (1) | DE602004020050D1 (pt) |
| DK (1) | DK1581504T3 (pt) |
| ES (1) | ES2322463T3 (pt) |
| FI (1) | FI116292B (pt) |
| IL (1) | IL168452A (pt) |
| MX (1) | MXPA05007217A (pt) |
| NO (1) | NO330965B1 (pt) |
| NZ (1) | NZ539831A (pt) |
| PL (1) | PL213564B1 (pt) |
| PT (1) | PT1581504E (pt) |
| RU (1) | RU2329253C2 (pt) |
| WO (1) | WO2004063168A1 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CL2008003553A1 (es) * | 2007-12-05 | 2009-11-27 | Grindeks Jsc | Proceso para preparar atipamezol o clorhidrato de 5-(2-etil-2,3-dihidro-1h-inden-2-il)-1h-imidazol: y loa compuestos intermediarios considerados en el proceso |
| EP2456749B1 (en) * | 2009-07-24 | 2016-03-30 | DSM Pharma Chemicals Regensburg GmbH | Indane derivatives for use as intermediates |
| EP2459540A4 (en) * | 2009-07-31 | 2012-12-19 | Reddys Lab Ltd Dr | PREPARATION OF FIPAMEZOLE |
| EP2502917A1 (en) * | 2011-03-17 | 2012-09-26 | Santhera Pharmaceuticals (Schweiz) AG | Solid state crystalline forms of 4-(2-ethyl-5-fluoro-2,3-dihydro-1H-inden-2-yl)-1H-imidazole |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI833794A0 (fi) * | 1983-10-18 | 1983-10-18 | Farmos Oy | Substituerade 2-merkapto-imidazoler |
| GB2167408B (en) * | 1984-11-23 | 1988-05-25 | Farmos Oy | Substituted imidazole derivatives and their preparation and use |
| AU7040500A (en) | 1999-09-06 | 2001-04-10 | Lg Chem Investment Ltd. | Process for preparing a 1-substituted 5-hydroxymethyl imidazole |
| US7091232B2 (en) | 2002-05-21 | 2006-08-15 | Allergan, Inc. | 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds |
-
2003
- 2003-01-08 FI FI20030026A patent/FI116292B/fi not_active IP Right Cessation
-
2004
- 2004-01-08 RU RU2005125044/04A patent/RU2329253C2/ru not_active IP Right Cessation
- 2004-01-08 ES ES04700707T patent/ES2322463T3/es not_active Expired - Lifetime
- 2004-01-08 BR BR0406676-6A patent/BRPI0406676A/pt not_active IP Right Cessation
- 2004-01-08 DE DE602004020050T patent/DE602004020050D1/de not_active Expired - Lifetime
- 2004-01-08 JP JP2006500148A patent/JP4592680B2/ja not_active Expired - Fee Related
- 2004-01-08 KR KR1020057012682A patent/KR101079065B1/ko not_active IP Right Cessation
- 2004-01-08 PT PT04700707T patent/PT1581504E/pt unknown
- 2004-01-08 PL PL378179A patent/PL213564B1/pl not_active IP Right Cessation
- 2004-01-08 US US10/537,177 patent/US7223871B2/en not_active Expired - Fee Related
- 2004-01-08 CN CNB2004800019799A patent/CN100339368C/zh not_active Expired - Fee Related
- 2004-01-08 EP EP04700707A patent/EP1581504B1/en not_active Expired - Lifetime
- 2004-01-08 MX MXPA05007217A patent/MXPA05007217A/es active IP Right Grant
- 2004-01-08 WO PCT/FI2004/000004 patent/WO2004063168A1/en active Application Filing
- 2004-01-08 AT AT04700707T patent/ATE425972T1/de active
- 2004-01-08 DK DK04700707T patent/DK1581504T3/da active
- 2004-01-08 AU AU2004203941A patent/AU2004203941B2/en not_active Ceased
- 2004-01-08 CA CA2511969A patent/CA2511969C/en not_active Expired - Fee Related
- 2004-01-08 NZ NZ539831A patent/NZ539831A/en not_active IP Right Cessation
-
2005
- 2005-05-05 IL IL168452A patent/IL168452A/en not_active IP Right Cessation
- 2005-08-01 NO NO20053712A patent/NO330965B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004203941A1 (en) | 2004-07-29 |
| KR101079065B1 (ko) | 2011-11-02 |
| EP1581504B1 (en) | 2009-03-18 |
| US20060025465A1 (en) | 2006-02-02 |
| RU2005125044A (ru) | 2006-01-20 |
| NO20053712L (no) | 2005-08-01 |
| PL378179A1 (pl) | 2006-03-06 |
| DK1581504T3 (da) | 2009-06-29 |
| JP4592680B2 (ja) | 2010-12-01 |
| FI20030026A (fi) | 2004-07-09 |
| JP2006515349A (ja) | 2006-05-25 |
| CA2511969C (en) | 2011-10-11 |
| CN100339368C (zh) | 2007-09-26 |
| FI116292B (fi) | 2005-10-31 |
| PT1581504E (pt) | 2009-05-26 |
| MXPA05007217A (es) | 2005-09-12 |
| CA2511969A1 (en) | 2004-07-29 |
| EP1581504A1 (en) | 2005-10-05 |
| AU2004203941B2 (en) | 2009-08-06 |
| US7223871B2 (en) | 2007-05-29 |
| ATE425972T1 (de) | 2009-04-15 |
| IL168452A (en) | 2009-07-20 |
| PL213564B1 (pl) | 2013-03-29 |
| RU2329253C2 (ru) | 2008-07-20 |
| FI20030026A0 (fi) | 2003-01-08 |
| CN1723202A (zh) | 2006-01-18 |
| KR20050091065A (ko) | 2005-09-14 |
| NZ539831A (en) | 2007-11-30 |
| WO2004063168A1 (en) | 2004-07-29 |
| DE602004020050D1 (de) | 2009-04-30 |
| ES2322463T3 (es) | 2009-06-22 |
| NO330965B1 (no) | 2011-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: PARA INT.CL: C07D 233/54, A61P 25/00 Ipc: C07D 233/54 (2011.01) |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 10A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014. |