ATE425972T1 - Verfahren zur herstellung substituierter imidazolderivate und in dem verfahren verwendete zwischenprodukte - Google Patents

Verfahren zur herstellung substituierter imidazolderivate und in dem verfahren verwendete zwischenprodukte

Info

Publication number
ATE425972T1
ATE425972T1 AT04700707T AT04700707T ATE425972T1 AT E425972 T1 ATE425972 T1 AT E425972T1 AT 04700707 T AT04700707 T AT 04700707T AT 04700707 T AT04700707 T AT 04700707T AT E425972 T1 ATE425972 T1 AT E425972T1
Authority
AT
Austria
Prior art keywords
sub
imidazole derivatives
substituted imidazole
intermediate products
products used
Prior art date
Application number
AT04700707T
Other languages
English (en)
Inventor
Rvi P Ivi Juuj
Seppo Parhi
Jaana Karjalainen
Original Assignee
Juvantia Pharma Ltd Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Juvantia Pharma Ltd Oy filed Critical Juvantia Pharma Ltd Oy
Application granted granted Critical
Publication of ATE425972T1 publication Critical patent/ATE425972T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
AT04700707T 2003-01-08 2004-01-08 Verfahren zur herstellung substituierter imidazolderivate und in dem verfahren verwendete zwischenprodukte ATE425972T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20030026A FI116292B (fi) 2003-01-08 2003-01-08 Menetelmä substituoitujen imidatsolijohdannaisten valmistamiseksi ja menetelmässä käytettäviä välituotteita

Publications (1)

Publication Number Publication Date
ATE425972T1 true ATE425972T1 (de) 2009-04-15

Family

ID=8565279

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04700707T ATE425972T1 (de) 2003-01-08 2004-01-08 Verfahren zur herstellung substituierter imidazolderivate und in dem verfahren verwendete zwischenprodukte

Country Status (21)

Country Link
US (1) US7223871B2 (de)
EP (1) EP1581504B1 (de)
JP (1) JP4592680B2 (de)
KR (1) KR101079065B1 (de)
CN (1) CN100339368C (de)
AT (1) ATE425972T1 (de)
AU (1) AU2004203941B2 (de)
BR (1) BRPI0406676A (de)
CA (1) CA2511969C (de)
DE (1) DE602004020050D1 (de)
DK (1) DK1581504T3 (de)
ES (1) ES2322463T3 (de)
FI (1) FI116292B (de)
IL (1) IL168452A (de)
MX (1) MXPA05007217A (de)
NO (1) NO330965B1 (de)
NZ (1) NZ539831A (de)
PL (1) PL213564B1 (de)
PT (1) PT1581504E (de)
RU (1) RU2329253C2 (de)
WO (1) WO2004063168A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2008003553A1 (es) * 2007-12-05 2009-11-27 Grindeks Jsc Proceso para preparar atipamezol o clorhidrato de 5-(2-etil-2,3-dihidro-1h-inden-2-il)-1h-imidazol: y loa compuestos intermediarios considerados en el proceso
US8563766B2 (en) 2009-07-24 2013-10-22 Dsm Pharma Chemicals Indane derivatives for use as intermediates
JP2013500983A (ja) * 2009-07-31 2013-01-10 ドクター・レディーズ・ラボラトリーズ・リミテッド フィパメゾールの調製
EP2502917A1 (de) * 2011-03-17 2012-09-26 Santhera Pharmaceuticals (Schweiz) AG Im Festzustand kristalline Formen von 4-(2-Ethyl-5-fluor-2,3-dihydro-1H-inden-2-yl)-1H-imidazol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI833794A0 (fi) 1983-10-18 1983-10-18 Farmos Oy Substituerade 2-merkapto-imidazoler
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use
CN1372551A (zh) 1999-09-06 2002-10-02 株式会社Lgci 制备1－取代的5－羟甲基咪唑的方法
US7091232B2 (en) * 2002-05-21 2006-08-15 Allergan, Inc. 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds

Also Published As

Publication number Publication date
RU2005125044A (ru) 2006-01-20
FI116292B (fi) 2005-10-31
DE602004020050D1 (de) 2009-04-30
MXPA05007217A (es) 2005-09-12
RU2329253C2 (ru) 2008-07-20
EP1581504A1 (de) 2005-10-05
CA2511969C (en) 2011-10-11
PL213564B1 (pl) 2013-03-29
AU2004203941A1 (en) 2004-07-29
US20060025465A1 (en) 2006-02-02
JP4592680B2 (ja) 2010-12-01
IL168452A (en) 2009-07-20
KR101079065B1 (ko) 2011-11-02
PL378179A1 (pl) 2006-03-06
US7223871B2 (en) 2007-05-29
WO2004063168A1 (en) 2004-07-29
AU2004203941B2 (en) 2009-08-06
FI20030026A0 (fi) 2003-01-08
ES2322463T3 (es) 2009-06-22
CN1723202A (zh) 2006-01-18
PT1581504E (pt) 2009-05-26
NZ539831A (en) 2007-11-30
FI20030026A (fi) 2004-07-09
EP1581504B1 (de) 2009-03-18
NO20053712L (no) 2005-08-01
NO330965B1 (no) 2011-08-29
KR20050091065A (ko) 2005-09-14
CN100339368C (zh) 2007-09-26
BRPI0406676A (pt) 2005-12-20
CA2511969A1 (en) 2004-07-29
JP2006515349A (ja) 2006-05-25
DK1581504T3 (da) 2009-06-29

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