ATE475653T1 - Verfahren zur herstellung von valsartan - Google Patents

Verfahren zur herstellung von valsartan

Info

Publication number
ATE475653T1
ATE475653T1 AT05815283T AT05815283T ATE475653T1 AT E475653 T1 ATE475653 T1 AT E475653T1 AT 05815283 T AT05815283 T AT 05815283T AT 05815283 T AT05815283 T AT 05815283T AT E475653 T1 ATE475653 T1 AT E475653T1
Authority
AT
Austria
Prior art keywords
formula
compound
valsartan
salt
pharmaceutically acceptable
Prior art date
Application number
AT05815283T
Other languages
English (en)
Inventor
Silvo Zupancic
Anica Pecavar
Rok Zupet
Original Assignee
Krka D D Novo Mesto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krka D D Novo Mesto filed Critical Krka D D Novo Mesto
Application granted granted Critical
Publication of ATE475653T1 publication Critical patent/ATE475653T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT05815283T 2004-11-30 2005-11-29 Verfahren zur herstellung von valsartan ATE475653T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04028356A EP1661891A1 (de) 2004-11-30 2004-11-30 Verfahren zur Herstellung von Valsartan
PCT/EP2005/012736 WO2006058701A1 (en) 2004-11-30 2005-11-29 A process for the synthesis of valsartan

Publications (1)

Publication Number Publication Date
ATE475653T1 true ATE475653T1 (de) 2010-08-15

Family

ID=34927585

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05815283T ATE475653T1 (de) 2004-11-30 2005-11-29 Verfahren zur herstellung von valsartan

Country Status (5)

Country Link
EP (2) EP1661891A1 (de)
AT (1) ATE475653T1 (de)
DE (1) DE602005022619D1 (de)
SI (1) SI1831186T1 (de)
WO (1) WO2006058701A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008035364A2 (en) * 2006-06-23 2008-03-27 Usv Limited Process for the preparation of micronized valsartan
EP2057132A2 (de) * 2006-07-03 2009-05-13 Aurobindo Pharma Limited Verfahren zur herstellung des angiotensin-ii-antagonisten valsartan
WO2008007391A2 (en) * 2006-07-10 2008-01-17 Manne Satyanarayana Reddy An improved process for the preparation of valsartan
CN100522953C (zh) * 2007-04-03 2009-08-05 浙江天宇药业有限公司 一种缬沙坦的新合成方法
JP2010526126A (ja) * 2007-05-07 2010-07-29 シプラ・リミテッド バルサルタンの製造方法
NZ580955A (en) 2007-05-07 2012-05-25 Cipla Ltd Process for preparing valsartan
CN101481374B (zh) * 2008-01-09 2013-01-09 浙江华海药业股份有限公司 1-三苯甲基-5-(1，1｀-联苯基-2基)-1h-四唑类化合物脱去三苯甲基的方法
US8492577B2 (en) 2008-04-07 2013-07-23 Hetero Research Foundation Process for preparation of valsartan intermediate
JP2010077077A (ja) * 2008-09-26 2010-04-08 Tokuyama Corp Ｎ−ペンタノイル−ｎ−［２’−（１ｈ−テトラゾール−５−イル）ビフェニル−４−イルメチル］−ｌ−バリンの製造方法
JPWO2012002189A1 (ja) * 2010-06-30 2013-08-22 株式会社トクヤマ バルサルタンの製造方法
WO2013072924A1 (en) * 2011-09-27 2013-05-23 Alkem Laboratories Ltd. An improved process for the preparation of angiotensin ii antagonists and intermediates thereof.
CN102617498B (zh) * 2012-03-16 2013-06-12 张家港市华昌药业有限公司 一种缬沙坦的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1600297A (en) * 1996-02-15 1997-09-02 Novartis Ag Aryl derivatives
WO2003089417A1 (en) * 2002-04-15 2003-10-30 Dr. Reddy's Laboratories Limited Novel crystalline forms of (s)-n-(1-carboxy-2-methyl-prop-1-yl) -n-pentanoyl-n- [2’-(1h-tetrazol-5-yl-)- biphenyl-4-yl methyl] amine (valsartan)
GB0222056D0 (en) * 2002-09-23 2002-10-30 Novartis Ag Process for the manufacture of organic compounds
EP1511739B1 (de) * 2003-03-17 2008-04-30 Teva Pharmaceutical Industries Ltd. Polymorphe formen von valsartan
EP1556363A2 (de) * 2003-04-21 2005-07-27 Teva Pharmaceutical Industries Limited Verfahren zur herstellung von valsartan und zwischenprodukte davon
EP1618097A1 (de) * 2003-04-21 2006-01-25 Teva Pharmaceutical Industries Ltd Verfahren zur herstellung von valsartan
CZ298685B6 (cs) * 2003-05-15 2007-12-19 Zentiva, A.S. Zpusob výroby N-(1-oxopentyl)-N-[[2´-(1H-tetrazol-5-yl)[1,1´-bifenyl]-4-yl]methyl]-L-valinu (valsartanu)
GB0316546D0 (en) * 2003-07-15 2003-08-20 Novartis Ag Process for the manufacture of organic compounds
EA011507B1 (ru) * 2003-08-27 2009-04-28 Зентива А.С. Способ получения калиевой соли лосартана

Also Published As

Publication number Publication date
EP1661891A1 (de) 2006-05-31
EP1831186A1 (de) 2007-09-12
DE602005022619D1 (de) 2010-09-09
SI1831186T1 (sl) 2010-10-29
EP1831186B1 (de) 2010-07-28
WO2006058701A1 (en) 2006-06-08

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